Latest & greatest articles for magnesium

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Top results for magnesium

121. The use of magnesium sulfate to prevent seizures in the pre-eclamptic gravida: a cost-effectiveness analysis

The use of magnesium sulfate to prevent seizures in the pre-eclamptic gravida: a cost-effectiveness analysis The use of magnesium sulfate to prevent seizures in the pre-eclamptic gravida: a cost-effectiveness analysis The use of magnesium sulfate to prevent seizures in the pre-eclamptic gravida: a cost-effectiveness analysis Blackwell S C, Tomlinson M W, Berman S, Redman M E, Hassan S S, Berry S M, Hallak M, Sorokin Y, Cotton D B Record Status This is a critical abstract of an economic (...) evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of magnesium sulphate (MgSO4) seizure prophylaxis for pre-eclamptic women. MgSO4 therapy was given as a 6.g bolus followed by a 2 g/hour continuous infusion. Type of intervention Treatment. Economic study type Cost-effectiveness analysis

NHS Economic Evaluation Database.2001

122. Magnesium sulphate versus lytic cocktail for eclampsia.

Magnesium sulphate versus lytic cocktail for eclampsia. BACKGROUND: Eclampsia, the occurrence of a seizure in association with pre-eclampsia, is a rare but serious complication of pregnancy. A number of different anticonvulsants are used to control eclamptic fits and to prevent further seizures. OBJECTIVES: The aim of this review was to compare the effects of magnesium sulphate with those of lytic cocktail when used for the care of women with eclampsia. SEARCH STRATEGY: The register of trials (...) held by the Cochrane Pregnancy and Childbirth Group was searched for relevant trials. The Cochrane Controlled Trials Register in The Cochrane Library Issue 2, 2000 was also searched. SELECTION CRITERIA: Randomised trials recruiting women with eclampsia, and comparing any use of magnesium sulphate with any use of lytic cocktail. DATA COLLECTION AND ANALYSIS: Data were extracted from each report without any blinding of the results or of the treatments which women received. MAIN RESULTS: Two trials

Cochrane2001

123. Magnesium supplementation in pregnancy.

Magnesium supplementation in pregnancy. BACKGROUND: Many women, especially those from disadvantaged backgrounds, have intakes of magnesium below recommended levels. Magnesium supplementation during pregnancy may be able to reduce fetal growth retardation and pre-eclampsia, and increase birth weight. OBJECTIVES: The objective of this review was to assess the effects of magnesium supplementation during pregnancy on maternal, neonatal and paediatric outcomes. SEARCH STRATEGY: We searched (...) the Cochrane Cochrane Controlled Trials Register. The date of the last search was June 2001. SELECTION CRITERIA: Randomised and quasi-randomised trials of dietary magnesium supplementation during pregnancy. DATA COLLECTION AND ANALYSIS: Suitability for inclusion and methodological quality were separately assessed by each reviewer. Data were independently extracted by the two reviewers. MAIN RESULTS: Seven trials involving 2689 women were included. Six of these trials randomly allocated women to either

Cochrane2001

124. Nexium (Esomeprazole Magnesium) Delayed-Release Capsules

Nexium (Esomeprazole Magnesium) Delayed-Release Capsules Drug Approval Package: Nexium (Esomeprazole Magnesium) NDA #21-153 & 21-154 Drug Approval Package U.S. Food & Drug Administration Enter Search terms Drug Approval Package - Nexium (Esomeprazole Magnesium) Delayed-Release Capsules Company: AstraZeneca LP Application No.: 21-153 & 21-154 Approval Date: 2/20/2001 (PDF) (PDF) Medical Review(s) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) (PDF) Clinical Pharmacology

FDA - Drug Approval Package2001

125. Intravenous magnesium as an adjuvant in acute bronchospasm: a meta-analysis

Intravenous magnesium as an adjuvant in acute bronchospasm: a meta-analysis Intravenous magnesium as an adjuvant in acute bronchospasm: a meta-analysis Intravenous magnesium as an adjuvant in acute bronchospasm: a meta-analysis Alter H J, Koepsell T D, Hilty W M Authors' objectives To evaluate intravenous magnesium sulphate as treatment for acute bronchospasm. Searching One author searched MEDLINE (from 1966 to 1998) and EMBASE (from 1990 to 1998) with no language restriction using two search (...) algorithms. Additional material was obtained by searching the bibliographies of selected articles, contacting authors of relevant clinical studies, and reviewing the abstracts of four scientific societies. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs). Case reports, case series, studies not specifying the clinical condition (i.e. acute versus stable asthma), and those in which magnesium was not delivered intravenously, were excluded from

DARE.2000

126. The effects of magnesium supplementation on exercise performance

The effects of magnesium supplementation on exercise performance The effects of magnesium supplementation on exercise performance The effects of magnesium supplementation on exercise performance Newhouse I J, Finstad E W Authors' objectives To critique research that has addressed the effects of magnesium (Mg) supplements on exercise performance in athletes. Searching MEDLINE was searched from 1966 to June 1999. Other electronic sources searched were CINAHL, International Bibliographic (...) Information on Dietary Supplements, and SPORTDiscus. The reference lists of recent articles were checked. Study selection Study designs of evaluations included in the review The studies included were experimental studies using magnesium supplements with performance as a dependent variable. Specific interventions included in the review Studies of Mg supplements as a treatment were eligible. The doses used in the included studies ranged from 116 to 500 mg/day for 1 day to 3 months. Multivitamins or minerals

DARE.2000

127. Efficacy of magnesium sulfate in acute adult asthma: a meta-analysis of randomized trials

Efficacy of magnesium sulfate in acute adult asthma: a meta-analysis of randomized trials Efficacy of magnesium sulfate in acute adult asthma: a meta-analysis of randomized trials Efficacy of magnesium sulfate in acute adult asthma: a meta-analysis of randomized trials Rodrigo G, Rodrigo C, Burschtin O Authors' objectives To determine whether magnesium sulfate (MgSO4) provides an additive improvement in adults with acute asthma presenting to the emergency department (ED). The specific questions (...) . The search was restricted to English language publications. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs) were included. Specific interventions included in the review Magnesium in the form of MgSO4, administered parenterally or by nebuliser. Participants included in the review Adult patients aged greater than 16 years, with acute asthma treated in the ED, were included. The mean age of participants was 38.3 years (plus or minus 13.4 years); 30

DARE.2000

128. Higher-Dose Intravenous Magnesium Therapy for Children With Moderate to Severe Acute Asthma

Higher-Dose Intravenous Magnesium Therapy for Children With Moderate to Severe Acute Asthma PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2000

129. Magnesium sulphate versus diazepam for eclampsia.

Magnesium sulphate versus diazepam for eclampsia. BACKGROUND: A number of different anticonvulsants are used to control eclamptic fits and to prevent future seizures. OBJECTIVES: The objective of this review was to assess the effects of magnesium sulphate compared with diazepam when used for the care of women with eclampsia. Magnesium sulphate is compared with phenytoin and with lytic cocktail (in preparation) in other Cochrane reviews. SEARCH STRATEGY: We searched the Cochrane Pregnancy (...) and Childbirth trials register and the Cochrane Controlled Trials Register, 1999 Issue 3. SELECTION CRITERIA: Randomised trials comparing magnesium sulphate (intravenous or intramuscular administration) with diazepam for women with a clinical diagnosis of eclampsia. DATA COLLECTION AND ANALYSIS: Trial quality was assessed and data extraction was done by the two reviewers. MAIN RESULTS: Five trials involving 1236 women were included. Most of these trials were of good quality. Magnesium sulphate was associated

Cochrane2000

130. Magnesium sulphate versus phenytoin for eclampsia.

Magnesium sulphate versus phenytoin for eclampsia. BACKGROUND: A number of different anticonvulsants are used to control eclamptic fits and to prevent further seizures. OBJECTIVES: The objective of this review was to assess the effects of magnesium sulphate compared with phenytoin when used for the care of women with eclampsia. Magnesium sulphate is compared with diazepam and with lytic cocktail (in preparation) in other Cochrane reviews. SEARCH STRATEGY: We searched the Cochrane Pregnancy (...) and Childbirth trials register and the Cochrane Controlled Trials Register, Issue 3 1999. SELECTION CRITERIA: Randomised trials comparing magnesium sulphate (intravenous or intramuscular administration) with phenytoin for women with a clinical diagnosis of eclampsia. DATA COLLECTION AND ANALYSIS: Trial quality was assessed and data extraction was done by two reviewers. MAIN RESULTS: Four trials involving 823 women were included. The trials were of good quality. Magnesium sulphate was associated

Cochrane2000

131. Magnesium supplementation in pregnancy.

Magnesium supplementation in pregnancy. BACKGROUND: Many women, especially those from disadvantaged backgrounds, have intakes of magnesium below recommended levels. Magnesium supplementation during pregnancy may be able to reduce fetal growth retardation and pre-eclampsia, and increase birthweight. OBJECTIVES: The objective of this review was to assess the effects of magnesium supplementation during pregnancy on maternal, neonatal and paediatric outcomes. SEARCH STRATEGY: We searched (...) the Cochrane Pregnancy and Childbirth Group trials register. SELECTION CRITERIA: Randomised and quasi-randomised trials of dietary magnesium supplementation during pregnancy. DATA COLLECTION AND ANALYSIS: Suitability for inclusion and methodological quality were separately assessed by each reviewer. Data were independently extracted by two reviewers. MAIN RESULTS: Six trials involving 2637 women were included. Only one of these trials was judged to be of high quality. Compared with placebo, oral magnesium

Cochrane2000

132. Magnesium for preventing preterm birth after threatened preterm labour.

Magnesium for preventing preterm birth after threatened preterm labour. BACKGROUND: Magnesium therapy is sometimes continued after an episode of threatened preterm labour in an attempt to prevent the onset of further preterm contractions. OBJECTIVES: The objective of this review was to assess the effects of magnesium maintenance therapy on preventing preterm birth after threatened preterm labour. SEARCH STRATEGY: We searched the Cochrane Pregnancy and Childbirth Group trials register. SELECTION (...) CRITERIA: Randomised controlled trials of magnesium therapy given to women after threatened preterm labour. DATA COLLECTION AND ANALYSIS: Trial quality assessment and data extraction were done independently by two reviewers. MAIN RESULTS: Two trials were included. Both were of poor quality and neither study included any long-term follow up of infants. The incidence of preterm birth or perinatal mortality was not reduced by magnesium maintenance therapy compared to alternative therapy or no treatment

Cochrane2000

133. Magnesium sulfate for treating exacerbations of acute asthma in the emergency department.

Magnesium sulfate for treating exacerbations of acute asthma in the emergency department. BACKGROUND: Treatment of acute asthma is based on rapid reversal of bronchospasm and arresting airway inflammation. There is some evidence that intravenous magnesium can provide additional bronchodilation when given in conjunction with standard bronchodilating agents and corticosteroids. No systematic review of this literature has been completed on this topic. OBJECTIVES: To examine the effect (...) of additional intravenous magnesium sulfate in patients with acute asthma managed in the emergency department. SEARCH STRATEGY: Randomised controlled trials were identified from the Cochrane Airways Review Group register. Bibliographies from included studies, known reviews and texts were searched. Primary authors and content experts were contacted. SELECTION CRITERIA: Randomised controlled trials or quasi-randomised trials were eligible for inclusion. Studies were included if patients presented with acute

Cochrane2000

134. Magnesium sulfate therapy in preeclampsia and eclampsia

Magnesium sulfate therapy in preeclampsia and eclampsia Magnesium sulfate therapy in preeclampsia and eclampsia Magnesium sulfate therapy in preeclampsia and eclampsia Witlin A G, Sibai B M Authors' objectives To review the available evidence regarding efficacy, benefits and risks of magnesium sulphate seizure prophylaxis in women with pre-eclampsia or eclampsia. Searching MEDLINE (1966 to February, 1998). The search terms are given. Bibliographies of retrieved articles were scanned and experts (...) were consulted to provide additional references. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs), non-randomised controlled trials of "historical interest", "classic" observational studies and recent retrospective studies. Specific interventions included in the review Magnesium sulphate therapy. Control therapies included phenytoin, diazepam, lytic cocktail, dihydralazine, methyl dopa, nifedipine, nimodipine, labetalol and placebo Participants

DARE.1998

135. Dietary magnesium intake and blood pressure: a qualitative overview of the observational studies

Dietary magnesium intake and blood pressure: a qualitative overview of the observational studies Dietary magnesium intake and blood pressure: a qualitative overview of the observational studies Dietary magnesium intake and blood pressure: a qualitative overview of the observational studies Mizushima S, Cappuccio FP, Nichols R, Elliott P Authors' objectives To re-assess the evidence from observational studies relating dietary magnesium intake to blood pressure (BP) in the light of recent reports (...) on this question. Searching MEDLINE (January 1966 to December 1995), BIDS-EMBASE (January 1980 to December 1995). Keywords searched for: magnesium, blood pressure and hypertension. Bibliographies of identified studies searched for further references and experts in the field contacted for further references. Papers in all languages were included. Study selection Study designs of evaluations included in the review Observational studies relating dietary intake of magnesium to BP. Specific interventions included

DARE.1998

136. Evidence for magnesium sulfate as a tocolytic agent

Evidence for magnesium sulfate as a tocolytic agent Evidence for magnesium sulfate as a tocolytic agent Evidence for magnesium sulfate as a tocolytic agent Macones G A, Sehdev H M, Berlin M, Morgan M A, Berlin J A Authors' objectives To assess the efficacy and side-effects of magnesium sulfate for acute tocolysis, compared with both placebo and beta-agonists. Searching Two authors independently searched MEDLINE from 1966 to 1996 for RCTs published in the English language, using the keywords (...) 'magnesium sulfate', 'premature labor' and 'tocolysis'. The bibliographies of the retrieved articles and obstetrical texts were also examined for additional studies. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs), which compared the use of magnesium sulfate with placebo, ritodrine or ritodrine plus other beta-agonists, to prevent pre-term birth. Specific interventions included in the review Magnesium sulfate (4 g loading dose, followed by 3 to 5 g

DARE.1997

137. Randomised trial of magnesium in in-hospital cardiac arrest. Duke Internal Medicine Housestaff.

Randomised trial of magnesium in in-hospital cardiac arrest. Duke Internal Medicine Housestaff. 9357406 1997 11 26 1997 11 26 2015 06 16 0140-6736 350 9087 1997 Nov 01 Lancet (London, England) Lancet Randomised trial of magnesium in in-hospital cardiac arrest. Duke Internal Medicine Housestaff. 1272-6 The apparent benefit of magnesium in acute myocardial infarction, and the persistently poor outcome after cardiac arrest, have led to use of magnesium in cardiopulmonary resuscitation. Because few (...) data on its use in cardiac arrest were available, we undertook a randomised placebo-controlled trial (MAGIC trial). Patients treated for cardiac arrest by the Duke Hospital code team were randomly assigned intravenous magnesium (2 g [8 mmoles] bolus, followed by 8 g [32 mmoles] over 24 h; 76 patients) or placebo (80 patients). Only patients in intensive care or general wards were eligible; those whose cardiac arrest occurred in emergency, operating, or recovery rooms were excluded. The primary

Lancet1997

138. Magnesium sulphate in the treatment of eclampsia and pre-eclampsia: an overview of the evidence from randomised trials

Magnesium sulphate in the treatment of eclampsia and pre-eclampsia: an overview of the evidence from randomised trials Magnesium sulphate in the treatment of eclampsia and pre-eclampsia: an overview of the evidence from randomised trials Magnesium sulphate in the treatment of eclampsia and pre-eclampsia: an overview of the evidence from randomised trials Chien P F, Khan K S, Arnott N Authors' objectives To evaluate the effectiveness of magnesium sulphate in the treatment of eclampsia (...) and pre-eclampsia by a systematic overview of controlled clinical trials. Searching MEDLINE was searched from 1966 to 1995 using a combination of the keywords 'magnesium sulphate' and 'pregnancy', the search being limited to 'humans'. Reference lists of all known primary research and review articles were examined and additional relevant citations were identified. Articles frequently cited were subsequently used (in the Science Citation Index) to identify additional studies that had cited these articles. Study

DARE.1996

139. Intravenous magnesium therapy for moderate to severe pediatric asthma: Results of a randomized, placebo-controlled trial.

Intravenous magnesium therapy for moderate to severe pediatric asthma: Results of a randomized, placebo-controlled trial. PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club1996

140. Efficacy of vitamin B6 and magnesium in the treatment of autism: a methodology review and summary of outcomes

Efficacy of vitamin B6 and magnesium in the treatment of autism: a methodology review and summary of outcomes Efficacy of vitamin B6 and magnesium in the treatment of autism: a methodology review and summary of outcomes Efficacy of vitamin B6 and magnesium in the treatment of autism: a methodology review and summary of outcomes Pfeiffer S I, Norton J, Nelson L, Shott S Authors' objectives To assess the effectiveness of vitamin B6 and magnesium in the treatment of autism, and to review (...) the methodology of studies in this area. Searching MEDLARS, PsycINFO and Mental Health Abstracts were searched, and the references of all studies published from 1975 were cross-checked. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs), non-randomised controlled trials and uncontrolled studies were included. Specific interventions included in the review Vitamin B6 with magnesium. Participants included in the review Persons with autism were included

DARE.1995