Latest & greatest articles for lithium

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Top results for lithium

41. Review: lithium reduces relapse rates in people with bipolar disorder

Review: lithium reduces relapse rates in people with bipolar disorder Review: lithium reduces relapse rates in people with bipolar disorder | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: lithium reduces relapse rates in people with bipolar disorder Article Text Therapeutics Review: lithium reduces relapse rates in people with bipolar disorder Free Michael Bauer , MD, PhD Statistics from Altmetric.com No Altmetric data available for this article. Geddes JR, Burgess S, Hawton K, et al . Long-term lithium therapy for bipolar disorder

Evidence-Based Mental Health2005

42. Lamotrigine and lithium are effective maintenance treatments in recently depressed people with bipolar I disorder

Lamotrigine and lithium are effective maintenance treatments in recently depressed people with bipolar I disorder Lamotrigine and lithium are effective maintenance treatments in recently depressed people with bipolar I disorder | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name (...) or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Lamotrigine and lithium are effective maintenance treatments in recently depressed people with bipolar I disorder Article Text Therapeutics Lamotrigine and lithium are effective maintenance treatments in recently depressed people with bipolar I disorder Free Federico Soldani

Evidence-Based Mental Health2005

43. Effectiveness and medical costs of divalproex versus lithium in the treatment of bipolar disorder: results of a naturalistic clinical trial

Effectiveness and medical costs of divalproex versus lithium in the treatment of bipolar disorder: results of a naturalistic clinical trial Effectiveness and medical costs of divalproex versus lithium in the treatment of bipolar disorder: results of a naturalistic clinical trial Effectiveness and medical costs of divalproex versus lithium in the treatment of bipolar disorder: results of a naturalistic clinical trial Revicki D A, Hirschfeld R M, Ahearn E P, Weisler R H, Palmer C, Keck P E Record (...) was lithium (Eskalith; GlaxoSmithKline) at a dose of up to 1,800 mg/day during acute mania treatment and between 900 and 1,200 mg/day for maintenance therapy. It was reported that the patients continued to receive their usual psychiatric care and that during the patients' hospitalisation the drug dose was titrated in order to achieve better clinical outcomes. In addition, investigators were allowed to prescribe other medications as clinically necessary to treat bipolar disorder. Type of intervention

NHS Economic Evaluation Database.2005

44. Long-term lithium therapy for bipolar disorder: systematic review and meta-analysis of randomized controlled trials

Long-term lithium therapy for bipolar disorder: systematic review and meta-analysis of randomized controlled trials Long-term lithium therapy for bipolar disorder: systematic review and meta-analysis of randomized controlled trials Long-term lithium therapy for bipolar disorder: systematic review and meta-analysis of randomized controlled trials Geddes J R, Burgess S, Hawton K, Jamison K, Goodwin G M CRD summary This review evaluated the efficacy and acceptability of lithium for relapse (...) prevention in bipolar disorder. It concluded that lithium reduces the risk of relapse in bipolar disorder, and that the preventive effect is clear for manic episodes but not for depressive episodes. Given some uncertainty in the review methodology, the validity of the authors' conclusions is unclear. Authors' objectives To determine the efficacy and acceptability of lithium for relapse prevention in bipolar disorder. Searching The Cochrane Controlled Trials Register and the Cochrane Depression, Anxiety

DARE.2004

45. Suicide risk in bipolar disorder during treatment with lithium and divalproex.

Suicide risk in bipolar disorder during treatment with lithium and divalproex. CONTEXT: Several studies have suggested that lithium treatment reduces risk of suicide in bipolar disorder, but no research has examined suicide risk during treatment with divalproex, the most commonly prescribed mood-stabilizing drug in the United States. OBJECTIVE: To compare risk of suicide attempt and suicide death during treatment with lithium with that during treatment with divalproex. DESIGN AND SETTING (...) : Retrospective cohort study conducted at 2 large integrated health plans in California and Washington. PATIENTS: Population-based sample of 20 638 health plan members aged 14 years or older who had at least 1 outpatient diagnosis of bipolar disorder and at least 1 filled prescription for lithium, divalproex, or carbamazepine between January 1, 1994, and December 31, 2001. Follow-up for each individual began with first qualifying prescription and ended with death, disenrollment from the health plan, or end

JAMA2003

46. Lithium treatment and suicide risk in major affective disorders: update and new findings

Lithium treatment and suicide risk in major affective disorders: update and new findings Lithium treatment and suicide risk in major affective disorders: update and new findings Lithium treatment and suicide risk in major affective disorders: update and new findings Baldessarini R J, Tondo L, Hennen J CRD summary This poorly reported review assessed suicidal risk reduction with long-term lithium maintenance. The authors' concluded that long-term maintenance with lithium is associated with major (...) reductions in risks of suicides and attempts in bipolar I disorder and other recurrent major affective illnesses. The review has several methodological weaknesses. The results from included studies and their subsequent synthesis may not be reliable. Authors' objectives To update and extend analyses of published data pertaining to suicidal behaviour in patients treated with and without lithium therapy (see Other Publications of Related Interest nos.1-3). Searching MEDLINE (from 1970 to mid-2002

DARE.2003

47. Lithium for schizophrenia.

Lithium for schizophrenia. BACKGROUND: Many people with schizophrenia do not achieve a satisfactory treatment response with ordinary antipsychotic drug treatment. In these cases, various add-on medications are used, among them lithium. OBJECTIVES: To review the effects of lithium for the treatment of schizophrenia and schizophrenia-like psychoses. SEARCH STRATEGY: The reviewers searched the Cochrane Schizophrenia Group's register (March 2002). This register is compiled by methodical searches (...) of BIOSIS, CINAHL, Dissertation abstracts, EMBASE, LILACS, MEDLINE, PSYNDEX, PsycINFO, RUSSMED, Sociofile, supplemented with hand searching of relevant journals and numerous conference proceedings. We also contacted pharmaceutical companies and authors of relevant studies to identify further trials and to obtain original patient data. SELECTION CRITERIA: All randomised controlled trials comparing lithium to antipsychotics or to placebo (or no intervention), whether as sole treatment or as an adjunct

Cochrane2003

48. Lower suicide risk with long-term lithium treatment in major affective illness: a meta-analysis

Lower suicide risk with long-term lithium treatment in major affective illness: a meta-analysis Lower suicide risk with long-term lithium treatment in major affective illness: a meta-analysis Lower suicide risk with long-term lithium treatment in major affective illness: a meta-analysis Tondo L, Hennen J, Baldessarini R J Authors' objectives To compare suicide rates with versus without long-term lithium treatment in major affective disorders. Searching An open-ended search of Current Contents (...) , MEDLINE, PsycLIT and PubMed was performed; no search terms or dates were reported. The authors also cross-referenced the results with publications on the topic dating from 1949 to December 2000. In addition, the indices and contents tables of leading international psychiatric research journals for the year 2000 were searched. Colleagues who had conducted studies of lithium treatment were contacted for unpublished data. The authors did not state whether any language restrictions were applied. Study

DARE.2001

49. Lithium for maintenance treatment of mood disorders.

Lithium for maintenance treatment of mood disorders. BACKGROUND: Mood disorders are common, disabling and tend to be recurrent. They carry a high risk of suicide. Maintenance treatment, aimed at the prevention of relapse, is therefore of vital importance. Lithium has been used for some years as the mainstay of maintenance treatment in bipolar affective disorder, and to a lesser extent in unipolar disorder. However, the efficacy and effectiveness of prophylactic lithium therapy has been disputed (...) . Low suicide rates in lithium-treated patients have led to claims that lithium has a specific anti-suicidal effect. If so, this is of considerable importance as treatments for mental disorders in general have not been shown convincingly to be effective in suicide prevention. OBJECTIVES: 1. To investigate the efficacy of lithium treatment in the prevention of relapse in recurrent mood disorders. 2. To examine the effect of lithium treatment on consumers' general health and social functioning, its

Cochrane2001

50. Lithium for maintenance treatment of mood disorders.

Lithium for maintenance treatment of mood disorders. BACKGROUND: Mood disorders are common, disabling and tend to be recurrent. They carry a high risk of suicide. Maintenance treatment, aimed at the prevention of relapse, is therefore of vital importance. Lithium has been used for some years as the mainstay of maintenance treatment in bipolar affective disorder, and to a lesser extent in unipolar disorder. However, the efficacy and effectiveness of prophylactic lithium therapy has been disputed (...) . Low suicide rates in lithium-treated patients have led to claims that lithium has a specific anti-suicidal effect. If so, this is of considerable importance as treatments for mental disorders in general have not been shown convincingly to be effective in suicide prevention. OBJECTIVES: 1. To investigate the efficacy of lithium treatment in the prevention of relapse in recurrent mood disorders. 2. To examine the effect of lithium treatment on consumers' general health and social functioning, its

Cochrane2001

51. Sex differences in response to lithium treatment

Sex differences in response to lithium treatment Sex differences in response to lithium treatment Sex differences in response to lithium treatment Viguera A C, Tondo L, Baldessarini R J Authors' objectives To investigate whether there are differences between the sexes in clinical response to lithium. Searching MEDLINE and Current Contents were searched (no dates or keywords were reported), and the reference lists of the identified reports were examined. The authors added data from their own (...) study. Study selection Study designs of evaluations included in the review The authors did not specify inclusion criteria relating to the study design, other than 'clinical trials'. They did, however, report whether the included studies were of a blinded or open design. Specific interventions included in the review Studies that used lithium as the primary treatment (of any duration) or permitted separate analysis of lithium-treated participants were eligible for inclusion in the review. The duration

DARE.2000

52. Systematic overview of lithium treatment in acute mania

Systematic overview of lithium treatment in acute mania Systematic overview of lithium treatment in acute mania Systematic overview of lithium treatment in acute mania Poolsup N, Li Wan Po A, de Oliveira I R Authors' objectives To evaluate the efficacy of lithium in the treatment of acute mania. Searching MEDLINE, EMBASE and Science Citation Index were searched from 1966 to the end of June 1999 were searched in addition to the Cochrane Library (Issue 1, 1999). MeSH terms were: 'lithium (...) ', 'bipolar disorder' and 'clinical trial'. This was followed by a textword search using 'mania' and 'acute treatment'. Reference lists of RCTs, narrative and systematic reviews were also searched. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs). The included studies were double blind, parallel group design; either single or double blind crossover; or open trials. Specific interventions included in the review Lithium (dosage not stated). The control

DARE.2000

53. Lithium induced cognitive side-effects in bipolar disorder: a qualitative analysis and implications for daily practice

Lithium induced cognitive side-effects in bipolar disorder: a qualitative analysis and implications for daily practice Lithium induced cognitive side-effects in bipolar disorder: a qualitative analysis and implications for daily practice Lithium induced cognitive side-effects in bipolar disorder: a qualitative analysis and implications for daily practice Honig A, Arts B M, Ponds R W, Riedel W J Authors' objectives To investigate whether lithium gives rise to cognitive side-effects and affects (...) the ability to drive a car. Searching MEDLINE and PsycLIT were searched from 1977 onwards using the key terms "cognition", "bipolar disorder" and "lithium". Study selection Study designs of evaluations included in the review Articles that scored more than 70 on the quality assessment were included in the review. Controlled and uncontrolled studies were included. Specific interventions included in the review Lithium taken for between 2 weeks and 9 years. Participants included in the review Patients

DARE.1999

54. Lithium augmentation in treatment-resistant-depression: meta-analysis of placebo-controlled studies

Lithium augmentation in treatment-resistant-depression: meta-analysis of placebo-controlled studies Lithium augmentation in treatment-resistant-depression: meta-analysis of placebo-controlled studies Lithium augmentation in treatment-resistant-depression: meta-analysis of placebo-controlled studies Bauer M, Dopfmer S Authors' objectives To determine whether evidence exists to support the clinical efficacy of lithium augmentation in refractory depression. Searching MEDLINE (1980 to June 1997 (...) ) was searched using the keywords 'lithium augmentation', 'lithium addition', 'lithium with augmentation', and 'lithium with depression'. The Cochrane Library (no dates given) was searched using the keywords 'lithium augmentation' and 'lithium addition'. An intensive search by hand using the references of published reviews on lithium augmentation and standard textbooks on refractory depression was undertaken. No language constraints were applied. Study selection Study designs of evaluations included

DARE.1999

55. [Prophylactic treatment of mood disorders: a cost-effectiveness analysis comparing lithium and carbamazepine]

[Prophylactic treatment of mood disorders: a cost-effectiveness analysis comparing lithium and carbamazepine] Traitement preventif des troubles de l'humeur: comparaison cout-efficacite du lithium et de la carbamazepine [Prophylactic treatment of mood disorders: a cost-effectiveness analysis comparing lithium and carbamazepine] Traitement preventif des troubles de l'humeur: comparaison cout-efficacite du lithium et de la carbamazepine [Prophylactic treatment of mood disorders: a cost (...) -effectiveness analysis comparing lithium and carbamazepine] Dardennes R, Lafuma A, Watkins S Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of carbamazepine or lithium for the prevention of mood disorder recurrences (unipolar

NHS Economic Evaluation Database.1999

56. Lithium compared to valproic acid and carbamazepine in the treatment of mania: a statistical meta-analysis

Lithium compared to valproic acid and carbamazepine in the treatment of mania: a statistical meta-analysis Lithium compared to valproic acid and carbamazepine in the treatment of mania: a statistical meta-analysis Lithium compared to valproic acid and carbamazepine in the treatment of mania: a statistical meta-analysis Emilien G, Maloteaux J M, Seghers A, Charles G Authors' objectives To determine the efficacy of lithium versus valproic acid and carbamazepine as a pharmacologic treatment (...) of manic-depressive illness. Searching The authors searched the MEDLINE database (dates of search and keywords used were not reported). The authors also made an informal search through Index Medicus. References from published studies were checked for additional relevant studies. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs) with double-blind evaluation of treatment outcome where the dose of lithium was within an acceptable therapeutic range

DARE.1996

57. A pharmacoeconomic model of divalproex vs lithium in the acute and prophylactic treatment of bipolar I disorder

A pharmacoeconomic model of divalproex vs lithium in the acute and prophylactic treatment of bipolar I disorder A pharmacoeconomic model of divalproex vs lithium in the acute and prophylactic treatment of bipolar I disorder A pharmacoeconomic model of divalproex vs lithium in the acute and prophylactic treatment of bipolar I disorder Keck P E, Nabulsi A A, Taylor J L, Henke C J, Chmiel J J, Stanton S P, Bennett J A Record Status This is a critical abstract of an economic evaluation that meets (...) the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Lithium vs divalproex for patients with acute mania in bipolar I disorders. Type of intervention Treatment and secondary prevention. Economic study type Cost effectiveness analysis. Study population Male and female patients with bipolar I disorders who had been

NHS Economic Evaluation Database.1996

58. Comparison of carbamazepine and lithium in the prophylaxis of bipolar disorders: a meta-analysis

Comparison of carbamazepine and lithium in the prophylaxis of bipolar disorders: a meta-analysis Comparison of carbamazepine and lithium in the prophylaxis of bipolar disorders: a meta-analysis Comparison of carbamazepine and lithium in the prophylaxis of bipolar disorders: a meta-analysis Dardennes R, Even C, Bange F, Heim A Authors' objectives To assess whether carbamazepine is as effective as lithium in the prophylaxis of bipolar disorders. Searching A manual and computerised bibliographic (...) search from 1970 to 1993 was undertaken. No search terms were stated. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs) with double blinding, which compared carbamazepine with lithium and allowed statistical treatment, were included. Specific interventions included in the review Lithium and carbamazepine. Participants included in the review Patients with bipolar disorders on American Psychiatric Association DSM-III criteria. Some primary studies

DARE.1995

59. Efficacy of divalproex vs lithium and placebo in the treatment of mania. The Depakote Mania Study Group.

Efficacy of divalproex vs lithium and placebo in the treatment of mania. The Depakote Mania Study Group. 8120960 1994 04 06 1994 04 06 2016 10 17 0098-7484 271 12 1994 Mar 23-30 JAMA JAMA Efficacy of divalproex vs lithium and placebo in the treatment of mania. The Depakote Mania Study Group. 918-24 To compare the effectiveness of divalproex sodium with that of lithium and placebo in patients with acute mania. Randomized, double-blind, parallel-group study of treatment outcomes in patients (...) with manic-depressive illness. A total of 179 hospitalized, acutely manic patients meeting the Research Diagnostic Criteria for manic disorder, approximately half of whom had been nonresponsive to lithium previously, were studied at nine university-affiliated hospitals. After a minimum 3-day washout period, random assignment for 21 days to divalproex, lithium, or placebo in a 2:1:2 ratio. Dosage of divalproex and lithium was increased if tolerated to a target concentration of 1041 mumol/L (150 micrograms

JAMA1994

60. Lithium treatment of depressed and nondepressed alcoholics.

Lithium treatment of depressed and nondepressed alcoholics. 2504944 1989 10 05 1989 10 05 2016 10 17 0098-7484 262 12 1989 Sep 22-29 JAMA JAMA Lithium treatment of depressed and nondepressed alcoholics. 1646-52 We assessed the efficacy of lithium carbonate in the treatment of 457 male alcoholics in a double-blind, placebo-controlled Department of Veterans Affairs Cooperative Study. Alcoholics either without depression or with a history of major depression, current major depression, or dysthymic (...) disorder were studied. Two hundred eighty-six alcoholics without depression and 171 alcoholics with depression began the 52-week outpatient study; 172 alcoholics (60.1%) without depression and 108 alcoholics (63.2%) with depression completed the study. Among both all alcoholics who began the study and a subgroup who completed the study, no significant differences between alcoholics who took lithium and those who took placebo were found for the following outcome measures:number of alcoholics abstinent

JAMA1989