Latest & greatest articles for lithium

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Top results for lithium

21. Efficacy and safety of long-term fluoxetine versus lithium monotherapy of bipolar II disorder: a randomized, double-blind, placebo-substitution study

Efficacy and safety of long-term fluoxetine versus lithium monotherapy of bipolar II disorder: a randomized, double-blind, placebo-substitution study 20360317 2010 07 02 2010 07 22 2016 12 15 1535-7228 167 7 2010 Jul The American journal of psychiatry Am J Psychiatry Efficacy and safety of long-term fluoxetine versus lithium monotherapy of bipolar II disorder: a randomized, double-blind, placebo-substitution study. 792-800 10.1176/appi.ajp.2009.09020284 The authors examined the safety (...) and efficacy of long-term fluoxetine monotherapy, lithium monotherapy, and placebo therapy in preventing relapse and recurrence of bipolar type II major depressive episode. The authors hypothesized that fluoxetine monotherapy would be superior to lithium monotherapy with a similar hypomanic mood conversion rate. Patients at least 18 years old who recovered from their major depressive episode during initial open-label fluoxetine monotherapy were randomly assigned to receive 50 weeks of double-blind

EvidenceUpdates2010 Full Text: Link to full Text with Trip Pro

22. Lithium carbonate in amyotrophic lateral sclerosis: Lack of efficacy in a dose-finding trial

Lithium carbonate in amyotrophic lateral sclerosis: Lack of efficacy in a dose-finding trial 20702794 2010 08 17 2010 09 13 2014 07 30 1526-632X 75 7 2010 Aug 17 Neurology Neurology Lithium carbonate in amyotrophic lateral sclerosis: lack of efficacy in a dose-finding trial. 619-25 10.1212/WNL.0b013e3181ed9e7c A neuroprotective effect of lithium in amyotrophic lateral sclerosis (ALS) has been recently reported. We performed a multicenter trial with lithium carbonate to assess its tolerability (...) of 171 patients had been enrolled, 87 randomized to the TG and 84 to the STG. The interim data analysis, performed per protocol, showed that 117 patients (68.4%) discontinued the study because of death/tracheotomy/severe disability, adverse events (AEs)/serious AEs (SAEs), or lack of efficacy. The Data Monitoring Committee recommended stopping the trial on November 2, 2009. Lithium was not well-tolerated in this cohort of patients with ALS, even at subtherapeutic doses. The 2 doses were equivalent

EvidenceUpdates2010

23. Lithium: still a cornerstone in the long-term treatment in bipolar disorder?

Lithium: still a cornerstone in the long-term treatment in bipolar disorder? Lithium: still a cornerstone in the long-term treatment in bipolar disorder? Lithium: still a cornerstone in the long-term treatment in bipolar disorder? Nivoli AM, Murru A, Vieta E CRD summary This review assessed the evidence from randomised controlled trials of long-term effects and effectiveness of lithium treatment for bipolar disorder. It concluded that data supports the effectiveness of lithium as a prophylactic (...) agent against mania, but not so much against bipolar depression. Due to limited synthesis and lack of study quality reporting, the results should be interpreted with caution. Authors' objectives To review the evidence from randomised controlled trials concerning the long-term effects and effectiveness of lithium treatment for bipolar disorder. Searching The authors searched MEDLINE and Cochrane Central Register of Controlled Trials (CENTRAL) for relevant studies published in English between January

DARE.2010

24. Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder (BALANCE): a randomised open-label trial.

Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder (BALANCE): a randomised open-label trial. 20092882 2010 02 01 2010 02 18 2016 11 22 1474-547X 375 9712 2010 Jan 30 Lancet (London, England) Lancet Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder (BALANCE): a randomised open-label trial. 385-95 10.1016/S0140-6736(09)61828-6 Lithium carbonate and valproate semisodium are both (...) recommended as monotherapy for prevention of relapse in bipolar disorder, but are not individually fully effective in many patients. If combination therapy with both agents is better than monotherapy, many relapses and consequent disability could be avoided. We aimed to establish whether lithium plus valproate was better than monotherapy with either drug alone for relapse prevention in bipolar I disorder. 330 patients aged 16 years and older with bipolar I disorder from 41 sites in the UK, France, USA

Lancet2010

25. Effects of lithium on cognitive performance: a meta-analysis

Effects of lithium on cognitive performance: a meta-analysis Effects of lithium on cognitive performance: a meta-analysis Effects of lithium on cognitive performance: a meta-analysis Wingo AP, Wingo TS, Harvey PD, Baldessarini RJ CRD summary This review found lithium carbonate had mild negative effects on cognitive performance in immediate verbal learning and memory and creativity. Some methodological flaws and the lack of information about the quality of the included studies means (...) that the reliability of the results is unclear and the authors' conclusions should be interpreted with caution. Authors' objectives To assess the effects of lithium on cognitive performance in the treatment of recurrent affective disorders. Searching MEDLINE, EMBASE and PsycINFO were searched from inception to December 2008 for relevant English-language studies; search terms were reported. Bibliographies of the included studies were also cross-referenced by hand. Study selection Comparative studies that evaluated

DARE.2009

26. Comparison of carbamazepine and lithium in treatment of bipolar disorder: a systematic review of randomized controlled trials

Comparison of carbamazepine and lithium in treatment of bipolar disorder: a systematic review of randomized controlled trials Comparison of carbamazepine and lithium in treatment of bipolar disorder: a systematic review of randomized controlled trials Comparison of carbamazepine and lithium in treatment of bipolar disorder: a systematic review of randomized controlled trials Ceron-Litvoc D, Soares BG, Geddes J, Litvoc J, de Lima MS CRD summary This review concluded that carbamazepine might (...) be comparable to lithium in terms of efficacy and safety in the treatment of acute manic and maintenance phase of bipolar disorder. The conclusions are appropriate for the evidence presented. Authors' objectives To assess the comparative efficacy of carbamazepine and lithium in the treatment of acute manic and maintenance phase of bipolar disorder. Searching MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), PsycLIT and LILACS were searched with no date restriction until December

DARE.2009

27. Suicidal risks during treatment of bipolar disorder patients with lithium versus anticonvulsants

Suicidal risks during treatment of bipolar disorder patients with lithium versus anticonvulsants Suicidal risks during treatment of bipolar disorder patients with lithium versus anticonvulsants Suicidal risks during treatment of bipolar disorder patients with lithium versus anticonvulsants Baldessarini RJ, Tondo L CRD summary The authors concluded that the few studies that compared suicide risks during long-term lithium treatment with anticonvulsant treatment in patients with bipolar disorder (...) were methodologically limited, but favoured lithium. The limited search, absence of a validity assessment and pooling of data from diverse studies, mean that the authors’ conclusions may not be reliable. Authors' objectives To compare suicide risks during long-term lithium treatment with anticonvulsants in patients with bipolar disorder. Searching MEDLINE was searched. Search terms were reported but search dates were not. In addition, reference lists of identified reports were screened. Study

DARE.2009

28. No difference in depression relapse rates between maintenance electroconvulsive therapy and lithium plus nortriptyline

No difference in depression relapse rates between maintenance electroconvulsive therapy and lithium plus nortriptyline No difference in depression relapse rates between maintenance electroconvulsive therapy and lithium plus nortriptyline | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user (...) name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here No difference in depression relapse rates between maintenance electroconvulsive therapy and lithium plus nortriptyline Article Text Therapeutics No difference in depression relapse rates between maintenance electroconvulsive therapy and lithium plus nortriptyline

Evidence-Based Mental Health2008

29. Comparison of short-term venlafaxine versus lithium monotherapy for bipolar II major depressive episode: a randomized open-label study

Comparison of short-term venlafaxine versus lithium monotherapy for bipolar II major depressive episode: a randomized open-label study 18344727 2008 03 17 2008 05 27 2015 11 19 0271-0749 28 2 2008 Apr Journal of clinical psychopharmacology J Clin Psychopharmacol Comparison of short-term venlafaxine versus lithium monotherapy for bipolar II major depressive episode: a randomized open-label study. 171-81 10.1097/JCP.0b013e318166c4e6 Practice guidelines for the initial treatment of bipolar II (BP (...) II) major depressive episode (MDE) recommend mood stabilizer (MS) monotherapy or combined MS plus antidepressant drug (AD) therapy. We hypothesized that initial AD monotherapy would be superior to MS monotherapy for BP II MDE with a low hypomanic switch rate. Bipolar II MDE patients were randomized to a 12-week open-label treatment with either venlafaxine monotherapy (n = 43) or lithium carbonate monotherapy (n = 40). The primary outcome measure was the 28-item Hamilton Depression Rating Scale

EvidenceUpdates2008

30. Lithium for schizophrenia.

Lithium for schizophrenia. BACKGROUND: Many people with schizophrenia do not achieve a satisfactory treatment response with ordinary antipsychotic drug treatment. In these cases, various add-on medications are used, among them lithium. OBJECTIVES: To review the effects of lithium for the treatment of schizophrenia and schizophrenia-like psychoses. SEARCH STRATEGY: We searched the Cochrane Schizophrenia Group's register (November 2006). This register is compiled by methodical searches of BIOSIS (...) , CINAHL, Dissertation abstracts, EMBASE, LILACS, MEDLINE, PSYNDEX, PsycINFO, RUSSMED, Sociofile, supplemented with hand searching of relevant journals and numerous conference proceedings. We also contacted pharmaceutical companies and authors of relevant studies to identify further trials and to obtain original patient data. SELECTION CRITERIA: We included all randomised controlled trials comparing lithium to antipsychotics or to placebo (or no intervention), whether as sole treatment or as an adjunct

Cochrane2007

31. Divalproex and lithium are similarly cost effective for adults with bipolar disorder

Divalproex and lithium are similarly cost effective for adults with bipolar disorder Divalproex and lithium are similarly cost effective for adults with bipolar disorder | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword (...) Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Divalproex and lithium are similarly cost effective for adults with bipolar disorder Article Text Therapeutics Divalproex and lithium are similarly cost effective for adults with bipolar disorder Statistics from Altmetric.com No Altmetric data available for this article. Request permissions If you wish to reuse any or all

Evidence-Based Mental Health2007

32. Lithium treatment reduces suicide risk in recurrent major depressive disorder

Lithium treatment reduces suicide risk in recurrent major depressive disorder Lithium treatment reduces suicide risk in recurrent major depressive disorder Lithium treatment reduces suicide risk in recurrent major depressive disorder Guzzetta F, Tondo L, Centorrino F, Baldessarini R J CRD summary This review evaluated the effect of lithium on the incidence of suicide and suicide attempts in patients with recurrent major depressive disorders. The authors concluded that treatment with lithium (...) might reduce the rate of suicide and suicide attempts. These conclusions have to be considered with caution given the limitations of the review in terms of the literature search, potential for bias, and failure to assess study quality. Authors' objectives To assess the effects of treatment with lithium on suicide and suicide attempts in patients with recurrent major depressive disorder (MDD). Searching MEDLINE was searched from January 1966 up to April 2006; the search terms were reported. One

DARE.2007

33. Acceleration and augmentation of antidepressants with lithium for depressive disorders: two meta-analyses of randomized, placebo-controlled trials

Acceleration and augmentation of antidepressants with lithium for depressive disorders: two meta-analyses of randomized, placebo-controlled trials Acceleration and augmentation of antidepressants with lithium for depressive disorders: two meta-analyses of randomized, placebo-controlled trials Acceleration and augmentation of antidepressants with lithium for depressive disorders: two meta-analyses of randomized, placebo-controlled trials Crossley N A, Bauer M CRD summary This review evaluated (...) the efficacy of lithium in accelerating and augmenting the clinical response of patients with depression. The authors concluded that lithium was an effective augmentation strategy. However, their conclusion may be strong given the small sample sizes of the included studies, lack of a validity assessment and poor reporting of review methodology. Authors' objectives To evaluate the efficacy of lithium in accelerating and in augmenting the clinical response of patients with depression. Searching MEDLINE (1966

DARE.2007

34. Magnitude of effect of lithium in short-term efficacy studies of moderate to severe manic episode

Magnitude of effect of lithium in short-term efficacy studies of moderate to severe manic episode Magnitude of effect of lithium in short-term efficacy studies of moderate to severe manic episode Magnitude of effect of lithium in short-term efficacy studies of moderate to severe manic episode Storosum J G, Wohlfarth T, Schene A, Elferink A, van Zweiten B J, van den Brink W CRD summary This review assessed the effect size of lithium in short-term efficacy studies of moderate to severe manic (...) episodes and concluded that lithium was effective. The reliability of the conclusion was unclear given the limitations of the review in terms of the literature search, reporting and possible methodological weaknesses. Authors' objectives To evaluate the effectiveness of lithium in the short-term treatment of people with moderate to severe manic episode. Searching MEDLINE and Embase were searched to March 2006 to identify relevant studies. Search terms were reported. Registration files submitted

DARE.2007

35. The incidence of delirium in older people with a mood disorder is similar with lithium and valproate

The incidence of delirium in older people with a mood disorder is similar with lithium and valproate The incidence of delirium in older people with a mood disorder is similar with lithium and valproate | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search (...) for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here The incidence of delirium in older people with a mood disorder is similar with lithium and valproate Article Text Prognosis The incidence of delirium in older people with a mood disorder is similar with lithium and valproate Free James A Bourgeois , OD MD Statistics from Altmetric.com No Altmetric

Evidence-Based Mental Health2006

36. Bipolar disorder in young people: divalproex sodium no more effective than lithium for maintenance

Bipolar disorder in young people: divalproex sodium no more effective than lithium for maintenance Bipolar disorder in young people: divalproex sodium no more effective than lithium for maintenance | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword (...) Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Bipolar disorder in young people: divalproex sodium no more effective than lithium for maintenance Article Text Therapeutics Bipolar disorder in young people: divalproex sodium no more effective than lithium for maintenance Free Gabrielle A Carlson , MD Statistics from Altmetric.com No Altmetric data

Evidence-Based Mental Health2006

37. Lithium may reduce gambling severity in pathological gamblers with bipolar disorder

Lithium may reduce gambling severity in pathological gamblers with bipolar disorder Lithium may reduce gambling severity in pathological gamblers with bipolar disorder | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main (...) menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Lithium may reduce gambling severity in pathological gamblers with bipolar disorder Article Text Therapeutics Lithium may reduce gambling severity in pathological gamblers with bipolar disorder Free Dr Robert Rogers , Professor Guy Goodwin Statistics from Altmetric.com No Altmetric data available for this article. Hollander E

Evidence-Based Mental Health2006

38. Loop diuretics and angiotensin converting enzyme inhibitors increased risk of hospital admission for lithium toxicity

Loop diuretics and angiotensin converting enzyme inhibitors increased risk of hospital admission for lithium toxicity Loop diuretics and angiotensin converting enzyme inhibitors increased risk of hospital admission for lithium toxicity | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name (...) or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Loop diuretics and angiotensin converting enzyme inhibitors increased risk of hospital admission for lithium toxicity Article Text Aetiology Loop diuretics and angiotensin converting enzyme inhibitors increased risk of hospital admission for lithium toxicity Free Maurice

Evidence-Based Medicine (Requires free registration)2006

39. Review: in people with schizophrenia, lithium is ineffective as sole therapy, while evidence on augmenting antipsychotics with lithium is inconclusive

Review: in people with schizophrenia, lithium is ineffective as sole therapy, while evidence on augmenting antipsychotics with lithium is inconclusive Review: in people with schizophrenia, lithium is ineffective as sole therapy, while evidence on augmenting antipsychotics with lithium is inconclusive | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: in people with schizophrenia, lithium is ineffective as sole therapy, while evidence on augmenting antipsychotics with lithium is inconclusive Article Text Therapeutics Review: in people

Evidence-Based Mental Health2005

40. Concomitant loop diuretics and ACE inhibitors increase risk of lithium toxicity in elderly people

Concomitant loop diuretics and ACE inhibitors increase risk of lithium toxicity in elderly people Concomitant loop diuretics and ACE inhibitors increase risk of lithium toxicity in elderly people | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword (...) Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Concomitant loop diuretics and ACE inhibitors increase risk of lithium toxicity in elderly people Article Text Aetiology Concomitant loop diuretics and ACE inhibitors increase risk of lithium toxicity in elderly people Free Robin Jacoby , DM, FRCP Statistics from Altmetric.com No Altmetric data available

Evidence-Based Mental Health2005