Latest & greatest articles for knee replacement

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Top results for knee replacement

1. Patient relevant outcomes of unicompartmental versus total knee replacement: systematic review and meta-analysis. (PubMed)

Patient relevant outcomes of unicompartmental versus total knee replacement: systematic review and meta-analysis. OBJECTIVE: To present a clear and comprehensive summary of the published data on unicompartmental knee replacement (UKA) or total knee replacement (TKA), comparing domains of outcome that have been shown to be important to patients and clinicians to allow informed decision making. DESIGN: Systematic review using data from randomised controlled trials, nationwide databases or joint

2019 BMJ

2. How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up. (PubMed)

How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up. BACKGROUND: Knee replacements are the mainstay of treatment for end-stage osteoarthritis and are effective. Given time, all knee replacements will fail and knowing when this failure might happen is important. We aimed to establish how long a knee replacement lasts. METHODS: In this systematic review and meta-analysis, we searched MEDLINE (...) and Embase for case series and cohort studies published from database inception until July 21, 2018. Articles reporting 15 year or greater survival of primary total knee replacement (TKR), unicondylar knee replacement (UKR), and patellofemoral replacements in patients with osteoarthritis were included. Articles that reviewed specifically complex primary surgeries or revisions were excluded. Survival and implant data were extracted, with all-cause survival of the knee replacement construct being

2019 Lancet

3. Partial knee replacements may save costs compared with total knee replacements

Partial knee replacements may save costs compared with total knee replacements Partial and total knee replacement costs compared Dissemination Centre Discover Portal NIHR DC Discover Partial knee replacements may save costs compared with total knee replacements Published on 27 November 2018 doi: Partial knee replacements, when performed by experienced surgeons, can save costs and improve quality of life compared with total knee replacements. Partial replacements for selected patients improve (...) quality of life and save between £600 and £2,000 over the patient’s lifetime, depending on age and gender. Knee replacements are commonly performed for people with ongoing pain and poor function. If the damage is limited to one side of the knee, it may be suitable to replace just the affected side (unicompartmental replacement) rather than replacing the entire knee joint. This study compared costs and quality of life associated with both procedures using the National Joint Registry for England

2019 NIHR Dissemination Centre

4. One-stage, instead of two-stage, surgery may be almost as safe for infected knee replacements

One-stage, instead of two-stage, surgery may be almost as safe for infected knee replacements Signal - One-stage, instead of two-stage, surgery may be almost as safe for infected knee replacements Dissemination Centre Discover Portal NIHR DC Discover One-stage, instead of two-stage, surgery may be almost as safe for infected knee replacements Published on 30 August 2016 A one-stage knee replacement procedure to treat an infected prosthetic knee may offer similar outcomes for most people (...) complications of knee replacement surgery. Using one-stage revision surgery to treat suitable patients would reduce hospital time and improve patient experience. Patient selection will remain important and patient registries could be used to monitor outcomes. Share your views on the research. Why was this study needed? Knee replacement surgery (arthroplasty) replaces a damaged or diseased knee with an artificial joint. More than 70,000 knee replacements are carried out in England and Wales each year

2019 NIHR Dissemination Centre

5. Nexgen found to be best value for total knee replacement

Nexgen found to be best value for total knee replacement Signal - Nexgen found to be best value for total knee replacement Dissemination Centre Discover Portal NIHR DC Discover Nexgen found to be best value for total knee replacement Published on 28 June 2016 This economic analysis, using routinely collected National Joint Registry data from 2003 to 2012, found that Nexgen was the most cost-effective brand of prosthesis for total knee replacement. The cheapest brand was AGC Biomet, but Nexgen (...) gave greater quality of life improvement, and the additional cost for the benefit - £2,300 per quality-adjusted life-year - was well within usual willingness to pay thresholds. Nexgen also had the lowest rates of revision surgery. The study is the first to compare commonly-used prostheses for patient outcomes, costs and revision rates (how soon the replacement knee needed replacing). The comparisons relied on non-randomised, routinely collected data, and although the authors made every effort

2019 NIHR Dissemination Centre

6. Two types of anaesthesia are safe for hip and knee replacements but one may reduce the time spent in hospital by a few hours

Two types of anaesthesia are safe for hip and knee replacements but one may reduce the time spent in hospital by a few hours Signal - Two types of anaesthesia are safe for hip and knee replacements but one may reduce the time spent in hospital by a few hours Dissemination Centre Discover Portal NIHR DC Discover Two types of anaesthesia are safe for hip and knee replacements but one may reduce the time spent in hospital by a few hours Published on 15 March 2016 Neuraxial anaesthesia (...) , administered around the nerves in the spine, was found to be as safe as general anaesthesia for people undergoing total hip or knee replacements. This review found a similar risk of dying, infection, nerve damage and blood clots in people regardless of the type of anaesthesia. Hospital stay was reduced on average by 0.4 days in the neuraxial anaesthesia group, though the significance to patients or impact on costs was not explored. Using neuraxial anaesthesia took no longer to perform than general

2019 NIHR Dissemination Centre

7. Knee replacement. (PubMed)

Knee replacement. Knee replacement surgery is one of the most commonly done and cost-effective musculoskeletal surgical procedures. The numbers of cases done continue to grow worldwide, with substantial variation in utilisation rates across regions and countries. The main indication for surgery remains painful knee osteoarthritis with reduced function and quality of life. The threshold for intervention is not well defined, and is influenced by many factors including patient and surgeon (...) preference. Most patients have a very good clinical outcome after knee replacement, but multiple studies have reported that 20% or more of patients do not. So despite excellent long-term survivorship, more work is required to enhance this procedure and development is rightly focused on increasing the proportion of patients who have successful pain relief after surgery. Changing implant design has historically been a target for improving outcome, but there is greater recognition that improvements can

2018 Lancet

8. Low molecular weight heparin versus other anti-thrombotic agents for prevention of venous thromboembolic events after total hip or total knee replacement surgery: a systematic review and meta-analysis (PubMed)

Low molecular weight heparin versus other anti-thrombotic agents for prevention of venous thromboembolic events after total hip or total knee replacement surgery: a systematic review and meta-analysis 30193575 2018 09 11 1471-2474 19 1 2018 Sep 08 BMC musculoskeletal disorders BMC Musculoskelet Disord Low molecular weight heparin versus other anti-thrombotic agents for prevention of venous thromboembolic events after total hip or total knee replacement surgery: a systematic review and meta (...) -analysis. 322 10.1186/s12891-018-2215-3 Venous thromboembolism (VTE) is an important complication following total hip replacement (THR) and total knee replacement (TKR) surgeries. Aim of this study was to comprehensively compare the clinical outcomes of low-molecular-weight heparin (LMWH) with other anticoagulants in patients who underwent TKR or THR surgery. Medline, Cochrane, EMBASE, and Google Scholar databases were searched for eligible randomized controlled studies (RCTs) published before June 30

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2018 EvidenceUpdates

9. Computer-Assisted Compared with Conventional Total Knee Replacement: A Multicenter Parallel-Group Randomized Controlled Trial

Computer-Assisted Compared with Conventional Total Knee Replacement: A Multicenter Parallel-Group Randomized Controlled Trial 30063588 2018 07 31 1535-1386 100 15 2018 Aug 01 The Journal of bone and joint surgery. American volume J Bone Joint Surg Am Computer-Assisted Compared with Conventional Total Knee Replacement: A Multicenter Parallel-Group Randomized Controlled Trial. 1265-1274 10.2106/JBJS.17.01338 We previously reported the short-term radiographic and functional results of a randomized (...) controlled trial (RCT) comparing computer-assisted and conventionally performed total knee replacement. We currently report the 2-year clinical results from this trial. One hundred and ninety patients were randomly allocated to undergo either computer-assisted or conventional total knee replacement. One hundred and seventy-two patients were available for clinical evaluation at 2 years, and 167 (97%) of those answered all patient-reported outcome measures (PROMs), including the Knee Injury

2018 EvidenceUpdates

10. Knee replacement

Knee replacement Top results for knee replacement - Trip Database or use your Google+ account Turning Research Into Practice My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box (...) and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for knee replacement The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical

2018 Trip Latest and Greatest

11. Early self-managed focal sensorimotor rehabilitative training enhances functional mobility and sensorimotor function in patients following total knee replacement: a controlled clinical trial

Early self-managed focal sensorimotor rehabilitative training enhances functional mobility and sensorimotor function in patients following total knee replacement: a controlled clinical trial 29473481 2018 02 23 1477-0873 2018 Feb 01 Clinical rehabilitation Clin Rehabil Early self-managed focal sensorimotor rehabilitative training enhances functional mobility and sensorimotor function in patients following total knee replacement: a controlled clinical trial. 269215518757291 10.1177 (...) /0269215518757291 To assess the effects of early self-managed focal sensorimotor training compared to functional exercise training after total knee replacement on functional mobility and sensorimotor function. A single-blind controlled clinical trial. University Hospital of Rion, Greece. A total of 52 participants following total knee replacement. The primary outcome was the Timed Up and Go Test and the secondary outcomes were balance, joint position error, the Knee Outcome Survey Activities of Daily Living

2018 EvidenceUpdates

12. Day-case surgery for total hip and knee replacement: How safe and effective is it? (PubMed)

Day-case surgery for total hip and knee replacement: How safe and effective is it? 29780620 2018 11 14 2058-5241 3 4 2018 Apr EFORT open reviews EFORT Open Rev Day-case surgery for total hip and knee replacement: How safe and effective is it? 130-135 10.1302/2058-5241.3.170031 Multimodal protocols for pain control, blood loss management and thromboprophylaxis have been shown to benefit patients by being more effective and as safe (fewer iatrogenic complications) as conventional protocols.Proper (...) , UK. Kellett Catherine F CF South West London Elective Orthopaedic Centre, UK. Kader Deiary F DF South West London Elective Orthopaedic Centre, UK. Villet Loïc L Centre de l'arthrose - Clinique du sport, Mérignac, France. Rivière Charles C South West London Elective Orthopaedic Centre, UK. MSK Lab, Imperial College London, UK. eng Journal Article 2018 04 27 England EFORT Open Rev 101695674 2058-5241 day case surgery hip arthroplasty knee arthroplasty ICMJE Conflict of interest statement: C

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2018 EFORT open reviews

13. Two types of anaesthesia are safe for hip and knee replacements but one may reduce the time spent in hospital by a few hours

Two types of anaesthesia are safe for hip and knee replacements but one may reduce the time spent in hospital by a few hours NIHR DC | Signal - Two types of anaesthesia are safe for hip and knee replacements but one may reduce the time spent in hospital by a few hours Dissemination Centre Discover Portal NIHR DC Discover NIHR Signal Two types of anaesthesia are safe for hip and knee replacements but one may reduce the time spent in hospital by a few hours Published on 15 March 2016 Neuraxial (...) anaesthesia, administered around the nerves in the spine, was found to be as safe as general anaesthesia for people undergoing total hip or knee replacements. This review found a similar risk of dying, infection, nerve damage and blood clots in people regardless of the type of anaesthesia. Hospital stay was reduced on average by 0.4 days in the neuraxial anaesthesia group, though the significance to patients or impact on costs was not explored. Using neuraxial anaesthesia took no longer to perform than

2018 NIHR Dissemination Centre

14. One-stage, instead of two-stage, surgery may be almost as safe for infected knee replacements

One-stage, instead of two-stage, surgery may be almost as safe for infected knee replacements NIHR DC | Signal - One-stage, instead of two-stage, surgery may be almost as safe for infected knee replacements Dissemination Centre Discover Portal NIHR DC Discover NIHR Signal One-stage, instead of two-stage, surgery may be almost as safe for infected knee replacements Published on 30 August 2016 A one-stage knee replacement procedure to treat an infected prosthetic knee may offer similar outcomes (...) of the most serious complications of knee replacement surgery. Using one-stage revision surgery to treat suitable patients would reduce hospital time and improve patient experience. Patient selection will remain important and patient registries could be used to monitor outcomes. Why was this study needed? Knee replacement surgery (arthroplasty) replaces a damaged or diseased knee with an artificial joint. More than 70,000 knee replacements are carried out in England and Wales each year, and the number

2018 NIHR Dissemination Centre

15. Nexgen found to be best value for total knee replacement

Nexgen found to be best value for total knee replacement NIHR DC | Signal - Nexgen found to be best value for total knee replacement Dissemination Centre Discover Portal NIHR DC Discover NIHR Signal Nexgen found to be best value for total knee replacement Published on 28 June 2016 This economic analysis, using routinely collected National Joint Registry data from 2003 to 2012, found that Nexgen was the most cost-effective brand of prosthesis for total knee replacement. The cheapest brand (...) was AGC Biomet, but Nexgen gave greater quality of life improvement, and the additional cost for the benefit - £2,300 per quality-adjusted life-year - was well within usual willingness to pay thresholds. Nexgen also had the lowest rates of revision surgery. The study is the first to compare commonly-used prostheses for patient outcomes, costs and revision rates (how soon the replacement knee needed replacing). The comparisons relied on non-randomised, routinely collected data, and although the authors

2018 NIHR Dissemination Centre

16. Medial subvastus versus the medial parapatellar approach for total knee replacement: A systematic review and meta-analysis of randomized controlled trials (PubMed)

Medial subvastus versus the medial parapatellar approach for total knee replacement: A systematic review and meta-analysis of randomized controlled trials Bone & Joint Login to your account Email Password Keep me logged in Change Password Old Password New Password Too Short Weak Medium Strong Very Strong Too Long Congrats! Your password has been changed Create a new account Email Can't sign in? Forgot your password? Enter your email address below and we will send you the reset instructions

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2018 EFORT open reviews

17. Sublingual sufentanil tablet system Zalviso® for postoperative analgesia after knee replacement in fast track surgery: a pilot observational study (PubMed)

Sublingual sufentanil tablet system Zalviso® for postoperative analgesia after knee replacement in fast track surgery: a pilot observational study 29557999 2018 11 14 2197-1153 5 1 2018 Mar 20 Journal of experimental orthopaedics J Exp Orthop Sublingual sufentanil tablet system Zalviso® for postoperative analgesia after knee replacement in fast track surgery: a pilot observational study. 8 10.1186/s40634-018-0123-y Currently many TKA protocols rely on multimodal analgesic protocols (...) Center for functional and biologic reconstruction of the Knee, Humanitas Clinical and Research Institute, Via Manzoni 113, 20089, Rozzano, Italy. eng Journal Article 2018 03 20 Germany J Exp Orthop 101653750 2197-1153 Continuous femoral nerve block Fast track Sublingual sufentanil tablet system Total knee arthroplasty Zalviso® 2017 10 18 2018 03 08 2018 3 21 6 0 2018 3 21 6 0 2018 3 21 6 1 epublish 29557999 10.1186/s40634-018-0123-y 10.1186/s40634-018-0123-y PMC5861254 Minerva Anestesiol. 2016 Apr;82

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2018 Journal of experimental orthopaedics

18. No Effect of Acupuncture as Adjunctive Therapy for Patients with Total Knee Replacement: A Randomized Controlled Trial

No Effect of Acupuncture as Adjunctive Therapy for Patients with Total Knee Replacement: A Randomized Controlled Trial 29294078 2018 01 02 1526-4637 2017 Dec 27 Pain medicine (Malden, Mass.) Pain Med No Effect of Acupuncture as Adjunctive Therapy for Patients with Total Knee Replacement: A Randomized Controlled Trial. 10.1093/pm/pnx317 Acupuncture is a low risk option in pain management following total knee replacement as an alternative to opioid analgesics. Therefore, the benefit (...) Rehabilitation, Health Centre Nørrebro, Copenhagen N, Denmark. Duus Benn B Department of Orthopaedic Surgery, Bispebjerg University Hospital, Copenhagen NV, Denmark. Juhl Carsten C Department of Rehabilitation, University Hospital of Copenhagen, Herlev and Gentofte, Hellerup, Denmark. eng Journal Article 2017 12 27 England Pain Med 100894201 1526-2375 Acupuncture Exercises Knee Arthroplasty Postoperative Pain Total Knee Replacement 2018 1 3 6 0 2018 1 3 6 0 2018 1 3 6 0 aheadofprint 29294078 4780338 10.1093

2018 EvidenceUpdates

19. No radiological and clinical advantages with patient-specific positioning guides in total knee replacement

No radiological and clinical advantages with patient-specific positioning guides in total knee replacement 29161930 2017 11 22 1745-3682 2017 Nov 22 Acta orthopaedica Acta Orthop No radiological and clinical advantages with patient-specific positioning guides in total knee replacement. 1-6 10.1080/17453674.2017.1393732 Background and purpose - Although the use of patient-specific positioning guides (PSPGs) in total knee replacement (TKR) in theory is promising, the technique has not yet proven (...) measured for both the femoral and tibial components in the frontal, sagit- tal, and axial plane. The Knee injury and Osteoarthritis Outcome Score (KOOS), the Eurocol-5D-3L (Eq5D) descriptive system and visual analogue scale (VAS), a pain score (NRS), and range of motion (ROM) were recorded preoperatively, and at 3 months, 1, and 2 years. The operation time and length of hospital stay were recorded. Results - 90 patients were available for postoperative CT mea- surements. A statistically significant

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2018 EvidenceUpdates

20. Effect of bisphosphonates on knee replacement surgery

Effect of bisphosphonates on knee replacement surgery 28988204 2017 10 08 2017 10 08 1468-2060 2017 Oct 07 Annals of the rheumatic diseases Ann. Rheum. Dis. Effect of bisphosphonates on knee replacement surgery. annrheumdis-2017-211811 10.1136/annrheumdis-2017-211811 Bone remodelling as a therapeutic target in knee osteoarthritis (OA) has gained much interest, but the effects of antiresorptive agents on knee OA have been conflicting, with no studies to date examining the effects (...) of bisphosphonate use on the clinically relevant endpoint of knee replacement (KR) surgery. We used data from The Health Improvement Network (THIN), a general practitioner electronic medical records representative of the general UK population. We identified older women who had initiated bisphosphonate use after their incident knee OA diagnosis. Each bisphosphonate initiator was propensity score-matched with a non-initiator within each 1-year cohort accrual block. The effect of bisphosphonates on the risk of KR

2017 EvidenceUpdates