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Latest & greatest articles for knee replacement
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on knee replacement or other clinical topics then use Trip today.
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Partial kneereplacement could be first choice for some patients with osteoarthritis. The studyBeard D, Davies L, Cook J, et al. The clinical and cost-effectiveness of total versus partial kneereplacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial. Lancet 2019;394:746-56.The study was funded by the NIHR Health Technology Assessment Programme (project number 08/14/08).To read the full NIHR Signal, go to https (...) ://discover.dc.nihr.ac.uk/content/signal-000824/partial-knee-replacement-could-be-first-choice-in-some-patients.Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
Consensus statement for perioperative care in total hip replacement and total kneereplacement surgery: Enhanced Recovery After Surgery (ERAS) Society recommendations Consensus statement for perioperative care in total hip replacement and total kneereplacement surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations: Acta Orthopaedica: Vol 0, No 0 | Search in: Journal 6,974 Views 0 CrossRef citations to date Altmetric Articles Consensus statement for perioperative care in total (...) hip replacement and total kneereplacement surgery: Enhanced Recovery After Surgery (ERAS ® ) Society recommendations , , , , , , & Published online: 30 Oct 2019 In this article Articles Consensus statement for perioperative care in total hip replacement and total kneereplacement surgery: Enhanced Recovery After Surgery (ERAS ® ) Society recommendations Ljungqvist O , Scott M , Fearon K C . Enhanced Recovery After Surgery: a review . JAMA Surg 2017 ; 152(3): 292 – 8 . , , , ). For total hip (THR
The effects of preoperative balance training on balance and functional outcome after total kneereplacement: a randomized controlled trial To assess the effects of preoperative balance training on the early postoperative balance and functional outcomes after total kneereplacement surgery and to test whether an outpatient intervention may be as effective as a domiciliary intervention.This is a three-arm randomized controlled trial.University hospital.Eighty-six individuals were recruited (...) showed no between-group differences and a small effect size (d < 0.5; P = 0.937). Secondary assessments suggested non-significant between-group differences.Preoperative balance training, conducted either as domiciliary or as an outpatient, is an effective approach to enhance early postoperative balance outcome but not the perceived functionality of individuals undergoing total kneereplacement.
Comparison of Topical and Intravenous Tranexamic Acid for Total KneeReplacement: A Randomized Double-Blinded Controlled Study of Effects on Tranexamic Acid Levels and Thrombogenic and Inflammatory Marker Levels Tranexamic acid (TXA) is an antifibrinolytic drug. Topical administration of TXA during total knee arthroplasty (TKA) is favored for certain patients because of concerns about thrombotic complications, despite a lack of supporting literature. We compared local and systemic levels
Self-Warming Blanket Versus Forced-Air Warming in Primary Knee or Hip Replacement: A Randomized Controlled Non-Inferiority Study. After primary total knee/hip replacement (TKR or THR respectively) a prosthetic joint infection (PJI) could develop. Hypothermia could raise the risk of infection. Heating by forced-air can disrupt laminar airfl ow in the operation room (OR), potentially raising the risk of infection. We aimed to study non-inferiority of an active self-heating blanket (SHB) compared
The clinical and cost-effectiveness of total versus partial kneereplacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial. Late-stage isolated medial knee osteoarthritis can be treated with total kneereplacement (TKR) or partial kneereplacement (PKR). There is high variation in treatment choice and little robust evidence to guide selection. The Total or Partial Knee Arthroplasty Trial (TOPKAT) therefore aims to assess (...) the clinical effectiveness and cost-effectiveness of TKR versus PKR in patients with medial compartment osteoarthritis of the knee, and this represents an analysis of the main endpoints at 5 years.Our multicentre, pragmatic randomised controlled trial was done at 27 UK sites. We used a combined expertise-based and equipoise-based approach, in which patients with isolated osteoarthritis of the medial compartment of the knee and who satisfied general requirements for a medial PKR were randomly assigned (1:1
2019LancetControlled trial quality: predicted high
Addition of Adductor Canal Block to Periarticular Injection for Total KneeReplacement: A Randomized Trial Periarticular injection is a popular method to control postoperative pain after total kneereplacement. An adductor canal block is a sensory block that can also help to alleviate pain after total kneereplacement. We hypothesized that the combination of adductor canal block and periarticular injection would allow patients to reach discharge criteria 0.5 day faster than with periarticular
Radiofrequency ablation of genicular nerves prior to total kneereplacement has no effect on postoperative pain outcomes: a prospective randomized sham-controlled trial with 6-month follow-up Refractory chronic knee pain from osteoarthritis (OA) is commonly treated with total knee arthroplasty (TKA). TKA can be associated with severe postoperative pain and persistent postsurgical knee pain. Poorly controlled postoperative pain can negatively effect functional outcomes following TKA (...) , and effective opioid-sparing analgesia is key to the ideal recovery. Genicular nerve radiofrequency ablation (GN-RFA) has been shown in several trials to be clinically effective in patients with severe refractory knee pain from OA. We aimed to assess if preoperative GN-RFA would improve postoperative pain outcomes following TKA.This was a sham-control prospective clinical trial in which blinded participants were randomized to image-guided GN-RFA or a simulated sham procedure 2-6 weeks prior to elective TKA
Perioperative Dietary Restriction of Carbohydrates in the Management of Blood Glucose Levels in Patients Undergoing Total KneeReplacement Approximately 75% of the US population over 65 years has prediabetes or diabetes. Despite current evidence for the efficacy of carbohydrate restriction in managing blood glucose, this practice has not been implemented as part of routine perioperative blood sugar management. We hypothesize that a carbohydrate reduced hospital diet (CRD) of 135 g/d may improve (...) blood sugar levels following total knee arthroplasty (TKA) compared to a non-carbohydrate reduced hospital diet (NCRD).We randomized non-insulin-dependent prediabetic and diabetic patients undergoing TKA to either an NCRD or a CRD. Sixty-four patients were enrolled in the study and 2 were excluded, leading to 62 patients in the final analysis. The NCRD group included 14 females (47%) and 16 males (53%), with mean age of 68.5 years (±6.3 years). The CRD group included 16 females (50%) and 16 males
Effectiveness of Later-Stage Exercise Programs vs Usual Medical Care on Physical Function and Activity After Total KneeReplacement: A Randomized Clinical Trial Several functional limitations persist after total kneereplacement (TKR). Intensive exercise programs could resolve these limitations but are not well tolerated by many patients until a later stage (>2 months) after surgery. Evidence for exercise at a later stage after TKR is limited.To compare the effectiveness of later-stage exercise (...) germane to kneereplacement and additional surveys of physical function. Data were analyzed by linear mixed models and responder analysis.A total of 240 participants (mean [SD] age, 70  years; 61.7% female) were allocated to physical therapy (n = 96), community exercise (n = 96), or control (n = 48). All 3 arms demonstrated clinically important improvement. At 3 months, between-arm analyses for the WOMAC-PF demonstrated no differences between physical therapy and community (-2.2; 98.3% CI, -4.5
The Effect of Prosthetic Design and Polyethylene Type on the Risk of Revision for Infection in Total KneeReplacement: An Analysis of 336,997 Prostheses from the Australian Orthopaedic Association National Joint Replacement Registry Periprosthetic infection following total kneereplacement remains alarmingly frequent, is devastating for patients, and is an increasingly substantial public health burden. While both the prosthetic design elements and type of polyethylene used in total knee (...) replacement can independently affect survivorship of the prosthesis, their influence on the risk of revision for infection is unknown. Therefore, we examined the effects of total knee prosthetic design and type of polyethylene bearing on the long-term revision risk for nonacute infection following total kneereplacement by comparing 4 different cohorts: patients who had minimally stabilized total knee prostheses with crosslinked polyethylene (XLPE) bearing surfaces, minimally stabilized total knee
Kneereplacement. Kneereplacement surgery is one of the most commonly done and cost-effective musculoskeletal surgical procedures. The numbers of cases done continue to grow worldwide, with substantial variation in utilisation rates across regions and countries. The main indication for surgery remains painful knee osteoarthritis with reduced function and quality of life. The threshold for intervention is not well defined, and is influenced by many factors including patient and surgeon (...) preference. Most patients have a very good clinical outcome after kneereplacement, but multiple studies have reported that 20% or more of patients do not. So despite excellent long-term survivorship, more work is required to enhance this procedure and development is rightly focused on increasing the proportion of patients who have successful pain relief after surgery. Changing implant design has historically been a target for improving outcome, but there is greater recognition that improvements can
Computer-Assisted Compared with Conventional Total KneeReplacement: A Multicenter Parallel-Group Randomized Controlled Trial We previously reported the short-term radiographic and functional results of a randomized controlled trial (RCT) comparing computer-assisted and conventionally performed total kneereplacement. We currently report the 2-year clinical results from this trial.One hundred and ninety patients were randomly allocated to undergo either computer-assisted or conventional total (...) kneereplacement. One hundred and seventy-two patients were available for clinical evaluation at 2 years, and 167 (97%) of those answered all patient-reported outcome measures (PROMs), including the Knee Injury and Osteoarthritis Outcome Score (KOOS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Knee Society Score (KSS), visual analog scale (VAS), and EuroQol-5 Dimensions (EQ-5D). Patients and clinical evaluators were blinded to the method of surgery. Surgical outcome
Kneereplacement Top results for kneereplacement - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 (...) or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for kneereplacement The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other
Early self-managed focal sensorimotor rehabilitative training enhances functional mobility and sensorimotor function in patients following total kneereplacement: a controlled clinical trial To assess the effects of early self-managed focal sensorimotor training compared to functional exercise training after total kneereplacement on functional mobility and sensorimotor function.A single-blind controlled clinical trial.University Hospital of Rion, Greece.A total of 52 participants following (...) for the experimental group over time were represented by a relative effect size range of 1.3-6.5.Overall, the magnitude of improvements in functional mobility and sensorimotor function endorses using focal sensorimotor training as an effective mode of rehabilitation following kneereplacement.
Day-case surgery for total hip and kneereplacement: How safe and effective is it? Multimodal protocols for pain control, blood loss management and thromboprophylaxis have been shown to benefit patients by being more effective and as safe (fewer iatrogenic complications) as conventional protocols.Proper patient selection and education, multimodal protocols and a well-defined clinical pathway are all key for successful day-case arthroplasty.By potentially being more effective, cheaper than
Sublingual sufentanil tablet system ZalvisoÂ® for postoperative analgesia after kneereplacement in fast track surgery: a pilot observational study Currently many TKA protocols rely on multimodal analgesic protocols with patient-controlled analgesia systems that administer opioids through a patient controlled IV infusion pump, in addition to concomitant peripheral nerve blocks and local anesthetics. Although effective, PCA IV opioids do not provide optimal results with fast track rehabilitation