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Latest & greatest articles for knee osteoarthritis
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on knee osteoarthritis or other clinical topics then use Trip today.
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Intra-articular use of hyaluronic acid in the treatment of kneeosteoarthritis Acido hialurónico intra-articular para artrosis de rodilla [Intra-articular use of hyaluronic acid in the treatment of kneeosteoarthritis] Acido hialurónico intra-articular para artrosis de rodilla [Intra-articular use of hyaluronic acid in the treatment of kneeosteoarthritis] Pichon Riviere A, Augustovski F, Garcia Marti S, Alcaraz A, Glujovsky D, Lopez A, Rey-Ares L, Bardach A, Ciapponi A Record Status (...) This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Pichon Riviere A, Augustovski F, Garcia Marti S, Alcaraz A, Glujovsky D, Lopez A, Rey-Ares L, Bardach A, Ciapponi A. Acido hialurónico intra-articular para artrosis de rodilla. [Intra-articular use of hyaluronic acid in the treatment of kneeosteoarthritis] Buenos Aires: Institute for Clinical Effectiveness and Health Policy
Worsening of pain and function over 5 years in individuals with 'early' OA is related to structural damage: data from the Osteoarthritis Initiative and CHECK (Cohort Hip & Cohort Knee) study 24243926 2015 01 08 2015 03 16 2016 11 25 1468-2060 74 2 2015 Feb Annals of the rheumatic diseases Ann. Rheum. Dis. Worsening of pain and function over 5 years in individuals with 'early' OA is related to structural damage: data from the Osteoarthritis Initiative and CHECK (Cohort Hip & Cohort Knee) study (...) . 347-53 10.1136/annrheumdis-2013-203829 To analyse the relation of joint damage on evolution of pain and physical functioning in two different cohorts of early phase of osteoarthritis (OA): Osteoarthritis Initiative (OAI) and Cohort Hip & Cohort Knee study (CHECK). Longitudinal data of 4-5 years follow-up (= medium term) of CHECK study and OAI were used. The Western Ontario and McMaster Universities of Osteoarthritis Index (WOMAC) was used to measure pain and physical functioning. For comparison
No Difference Between Intra-Articular Injection of Hyaluronic Acid and Placebo for Mild to Moderate KneeOsteoarthritis: A Randomized, Controlled, Double-Blind Trial 25548079 2015 05 08 2016 02 04 2015 05 08 1532-8406 30 5 2015 May The Journal of arthroplasty J Arthroplasty No difference between intra-articular injection of hyaluronic acid and placebo for mild to moderate kneeosteoarthritis: a randomized, controlled, double-blind trial. 754-7 10.1016/j.arth.2014.12.012 S0883-5403(14)00943-7 (...) The main goal of our study was to examine the effectiveness and safety of Fermathron plus, a specific brand of hyaluronic acid (HA), in patients with mild to moderate kneeosteoarthritis. In a randomized, controlled, double-blind trial, 196 patients with symptomatic kneeosteoarthritis (mean age ± SD, 59.4 ± 9.9 years, Kellgren-Lawrence grade 1-3) were given either 3 weekly intra-articular injections of HA or saline (placebo). Although pain and functional scores (WOMAC scale) improved significantly
Platelet-rich plasma injections for osteoarthritis of the knee (IPG491) Platelet-rich plasma injections for osteoarthritis of the knee | Guidance and guidelines | NICE Platelet-rich plasma injections for osteoarthritis of the knee Interventional procedures guidance [IPG491] Published date: May 2014 Share Save Guidance W90.3 Injection of therapeutic substance into joint Y53.2 Approach to organ under ultrasonic control Z84.6 Knee joint X36.8 Other specified blood withdrawal In addition a code (...) from the ICD-10 category M17 Gonarthrosis [arthrosis of knee] would be recorded. Your responsibility This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, healthcare professionals are expected to take this guidance fully into account. However, the guidance does not override the individual responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient
The Non-Surgical Management of Hip & KneeOsteoarthritis (OA) VA/DoD CLINICAL PRACTICE GUIDELINE FOR THE NON-SURGICAL MANAGEMENT OF HIP & KNEEOSTEOARTHRITIS Department of Veterans Affairs Department of Defense QUALIFYING STATEMENTS The Department of Veterans Affairs and the Department of Defense guidelines are based upon the best information available at the time of publication. They are designed to provide information and assist decision-making. They are not intended to define a standard (...) and/or therapeutic interventions within these guidelines does not guarantee coverage of civilian sector care. Additional information on current TRICARE benefits may be found at www.tricare.mil or by contacting your regional TRICARE Managed Care Support Contractor. Version 1.0 – 2014 Prepared by: THE NON-SURGICAL MANAGEMENT OF HIP & KNEEOSTEOARTHRITIS Working Group With support from: The Office of Quality and Performance, VA, Washington, DC & Office of Evidence Based Practice, US Army Medical Command Version 1.0
Preoperative physical therapy for severe osteoarthritis of the knee Preoperative physical therapy for severe osteoarthritis of the knee Preoperative physical therapy for severe osteoarthritis of the knee Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Preoperative physical therapy for severe osteoarthritis of the knee. Lansdale: HAYES, Inc.. Directory (...) Status Subject indexing assigned by CRD MeSH Activities of Daily Living; Adults; Arthroplasty, Replacement, Knee; Exercise Therapy; Knee Joint; Osteoarthritis, Knee; Pain; Physical Therapy Modalities; Preoperative Care; Range of Motion, Articular; Recovery of Function; Treatment Outcome Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence HAYES, Inc., 157 S. Broad Street, Suite 200, Lansdale, PA 19446
US-approved intra-articular hyaluronic acid injections are safe and effective in patients with kneeosteoarthritis: systematic review and meta-analysis of randomized, saline-controlled trials US-approved intra-articular hyaluronic acid injections are safe and effective in patients with kneeosteoarthritis: systematic review and meta-analysis of randomized, saline-controlled trials US-approved intra-articular hyaluronic acid injections are safe and effective in patients with kneeosteoarthritis (...) : systematic review and meta-analysis of randomized, saline-controlled trials Miller LE, Block JE CRD summary This review concludes that intra-articular hyaluronic acid injections for symptomatic kneeosteoarthritis were safe and effective. The former conclusion may have confused the absence of evidence with the evidence of absence; the latter conclusion did not sufficiently consider variability in effectiveness or potential biases in the evidence-base. Thus, these conclusions cannot be considered reliable
Does Running Cause KneeOsteoarthritis? Does Running Cause KneeOsteoarthritis? | Clinical Correlations Does Running Cause KneeOsteoarthritis? September 14, 2013 By Karin Katz, MD Faculty Peer Reviewed Post-summer is here. Despite the heat and what feels like 100% humidity, the East River Path is packed with runners. No amount of car fumes pouring onto the path could stop those in training. Others are circling the 6-mile-loop around Central Park. Or, if you are bored of running the typical (...) of kneeosteoarthritis. Felson et al. published a longitudinal study of the Framinghmam Offspring cohort to evaluate the long-term A total of 1,279 subjects were included with a mean age at baseline of 53 years. Most reported walking for exercise. Subjects were asked about their knee pain and anteroposterior and lateral knee radiographs were obtained. Nine years later, subjects were reexamined for osteoarthritis. The primary outcomes of the study included incident radiographic OA, symptomatic OA, and
Efficacy and safety of tanezumab added on to diclofenac sustained release in patients with knee or hip osteoarthritis: a double-blind, placebo-controlled, parallel-group, multicentre phase III randomised clinical trial 23852695 2014 08 02 2014 10 16 2017 02 03 1468-2060 73 9 2014 Sep Annals of the rheumatic diseases Ann. Rheum. Dis. Efficacy and safety of tanezumab added on to diclofenac sustained release in patients with knee or hip osteoarthritis: a double-blind, placebo-controlled, parallel (...) -group, multicentre phase III randomised clinical trial. 1665-72 10.1136/annrheumdis-2012-203164 Tanezumab, a monoclonal antibody, inhibits nerve growth factor and reduces chronic pain. This randomised, double-blind, controlled multicentre study was conducted to evaluate the efficacy and safety of tanezumab added to oral diclofenac sustained release (DSR) in patients with hip or kneeosteoarthritis (OA) pain. Patients (N=604) with moderate to severe knee or hip OA tolerating stable DSR were
Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with kneeosteoarthritis: the IDEA randomized clinical trial. IMPORTANCE: Kneeosteoarthritis (OA), a common cause of chronic pain and disability, has biomechanical and inflammatory origins and is exacerbated by obesity. OBJECTIVE: To determine whether a ≥10% reduction in body weight induced by diet, with or without exercise, would improve mechanistic and clinical (...) outcomes more than exercise alone. DESIGN, SETTING, AND PARTICIPANTS: Single-blind, 18-month, randomized clinical trial at Wake Forest University between July 2006 and April 2011. The diet and exercise interventions were center-based with options for the exercise groups to transition to a home-based program. Participants were 454 overweight and obese older community-dwelling adults (age ≥55 years with body mass index of 27-41) with pain and radiographic kneeOA. INTERVENTIONS: Intensive diet-induced
Efficacy and safety of strontium ranelate in the treatment of kneeosteoarthritis: results of a double-blind, randomised placebo-controlled trial 23117245 2013 01 07 2013 03 12 2016 11 25 1468-2060 72 2 2013 Feb Annals of the rheumatic diseases Ann. Rheum. Dis. Efficacy and safety of strontium ranelate in the treatment of kneeosteoarthritis: results of a double-blind, randomised placebo-controlled trial. 179-86 10.1136/annrheumdis-2012-202231 Strontium ranelate is currently used (...) for osteoporosis. The international, double-blind, randomised, placebo-controlled Strontium ranelate Efficacy in KneeOsteoarthrItis triAl evaluated its effect on radiological progression of kneeosteoarthritis. Patients with kneeosteoarthritis (Kellgren and Lawrence grade 2 or 3, and joint space width (JSW) 2.5-5 mm) were randomly allocated to strontium ranelate 1 g/day (n=558), 2 g/day (n=566) or placebo (n=559). The primary endpoint was radiographical change in JSW (medial tibiofemoral compartment) over 3
A randomized controlled trial on the efficacy of intermittent and continuous traction for patients with kneeosteoarthritis 22960239 2013 03 29 2013 09 13 2013 03 29 1477-0873 27 4 2013 Apr Clinical rehabilitation Clin Rehabil A randomized controlled trial on the efficacy of intermittent and continuous traction for patients with kneeosteoarthritis. 347-54 10.1177/0269215512459062 To investigate the efficacy of intermittent and continuous traction in the treatment of kneeosteoarthritis. A (...) randomized, controlled, observer-blind seven-week trial. Hospital-based outpatient practice. Ninety-eight patients with stage 3 kneeosteoarthritis according to Kellgren-Lawrence radiological rating scale. All 98 patients were randomly assigned to three treatment groups, for three weeks (weekends excluded). The control group (n=30, mean age: 59.30±8.16) received hot pack and short wave diathermy; the intermittent group (n=30, mean age: 58.20±7.78) received hot pack, short wave diathermy and intermittent
Meta-analysis: acupuncture for osteoarthritis of the knee. Meta-analysis: acupuncture for os... preview & related info | Mendeley E-mail address Password ( ) Remember me …or sign in with Search Main Navigation › Short URL Annals of Internal Medicine ( 2007 ) Volume: 146 , Issue: 12 , Pages: 868-877 PubMed: Available from or Find this paper at: Abstract BACKGROUND: Kneeosteoarthritis is a major cause of pain and functional limitation. PURPOSE: To evaluate the effects of acupuncture for treating (...) kneeosteoarthritis. DATA SOURCES: Cochrane Central Register of Controlled Trials, MEDLINE, and EMBASE databases to January 2007. No language restrictions were applied. STUDY SELECTION: Randomized trials longer than 6 weeks in duration that compared needle acupuncture with a sham, usual care, or waiting list control group for patients with kneeosteoarthritis. DATA EXTRACTION: Two authors independently agreed on eligibility, assessed methodological quality and acupuncture adequacy, and extracted
Published trials of nonmedicinal and noninvasive therapies for hip and kneeosteoarthritis. Published trials of nonmedicinal ... preview & related info | Mendeley E-mail address Password ( ) Remember me …or sign in with Search Main Navigation › Short URL Annals of Internal Medicine ( 1994 ) Volume: 121 , Issue: 2 , Publisher: Vanderbilt University, Nashville, Tennessee. , Pages: 133-140 PubMed: Available from or Find this paper at: Abstract PURPOSE: To review the efficacy of nonmedicinal (...) , noninvasive therapies in hip and kneeosteoarthritis. DATA SOURCES: Search of English-language literature from 1966 through 1993 using MEDLINE by cross-referencing "osteoarthritis" (therapy subheadings) with "controlled trial," "comparative study," or "trial(s)." STUDY SELECTION: Fifteen controlled trials of diathermy (deep heat), exercise, acupuncture, transcutaneous electrical nerve stimulation, topically applied capsaicin, low-energy laser, and pulsed electromagnetic fields were found. No experimental