Latest & greatest articles for knee osteoarthritis

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Top results for knee osteoarthritis

61. Clinical efficacy of intra-articular injections in knee osteoarthritis: a prospective randomized study comparing hyaluronic acid and betamethasone.

Clinical efficacy of intra-articular injections in knee osteoarthritis: a prospective randomized study comparing hyaluronic acid and betamethasone. 27790040 2016 10 28 2017 02 20 7 2015 Open access rheumatology : research and reviews Open Access Rheumatol Clinical efficacy of intra-articular injections in knee osteoarthritis: a prospective randomized study comparing hyaluronic acid and betamethasone. 9-18 Osteoarthritis (OA) is the most common joint disease and leading cause of disability (...) . Intra-articular (IA) administration of hyaluronic acid (HA) or corticosteroids (CS) have been previously studied, though using insufficient number of patients or short follow-up periods. We evaluate HA and CS in patients with knee OA in terms of clinical efficacy over 12 months. We used a prospective, randomized study with parallel groups. Randomized patients received IA injections of HA or betamethasone (BM). The primary outcomes were improvement in pain using Visual Analog Scale and function

Open access rheumatology : research and reviews2016 Full Text: Link to full Text with Trip Pro

62. Efficacy of a natural mineral complex in North American adults with osteoarthritis of the knee: a randomized double-blind placebo-controlled study.

Efficacy of a natural mineral complex in North American adults with osteoarthritis of the knee: a randomized double-blind placebo-controlled study. 27790038 2016 10 28 2017 02 20 6 2014 Open access rheumatology : research and reviews Open Access Rheumatol Efficacy of a natural mineral complex in North American adults with osteoarthritis of the knee: a randomized double-blind placebo-controlled study. 91-103 This study evaluated the efficacy of a hydrothermal mineral complex (HMC) supplement (...) in participants with knee osteoarthritis. This was a double-blind, placebo-controlled, 12-week crossover study with 150 participants receiving either placebo or HMC for 4 weeks, with a 4-week washout period. The primary endpoint was WOMAC™ pain, and secondary endpoints were WOMAC™ physical function and stiffness, the 36-Item Short Form Health Survey (SF-36), high-sensitivity C-reactive protein, tumor necrosis factor α, interleukin 6, and safety. There were no significant differences in WOMAC™ pain, stiffness

Open access rheumatology : research and reviews2016 Full Text: Link to full Text with Trip Pro

63. Unique aspects of pain reduction in osteoarthritis of the knee with LMWF-5A.

Unique aspects of pain reduction in osteoarthritis of the knee with LMWF-5A. 27790041 2016 10 28 2017 02 20 7 2015 Open access rheumatology : research and reviews Open Access Rheumatol Unique aspects of pain reduction in osteoarthritis of the knee with LMWF-5A. 19-22 Osteoarthritis of the knee (OAK) is a common form of arthritis that can lead to substantial pain and disability. This commentary highlights key aspects of the recently published phase 3 A Efficacy and Safety Study of Two Doses (...) of Intra-Articular Injection of Ampion™ in Adults With Pain Due to Osteoarthritis of the Knee (SPRING) study. SPRING (NCT01839331) was a multicenter, randomized, vehicle-controlled, double-blind trial that evaluated the safety and efficacy of the low-molecular-weight fraction of 5% human serum albumin (LMWF-5A) for treatment of pain, measured by the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) pain scale, in patients with symptomatic OAK (N=329). Patients in this study reflected

Open access rheumatology : research and reviews2016 Full Text: Link to full Text with Trip Pro

64. Gait analysis of patients with knee osteoarthritis highlights a pathological mechanical pathway and provides a basis for therapeutic interventions

Gait analysis of patients with knee osteoarthritis highlights a pathological mechanical pathway and provides a basis for therapeutic interventions 28461915 2018 11 13 2058-5241 1 10 2016 Oct EFORT open reviews EFORT Open Rev Gait analysis of patients with knee osteoarthritis highlights a pathological mechanical pathway and provides a basis for therapeutic interventions. 368-374 10.1302/2058-5241.1.000051 Knee osteoarthritis (OA) is a painful and incapacitating disease affecting a large portion (...) of the elderly population, for which no cure exists. There is a critical need to enhance our understanding of OA pathogenesis, as a means to improve therapeutic options.Knee OA is a complex disease influenced by many factors, including the loading environment. Analysing knee biomechanics during walking - the primary cyclic load-bearing activity - is therefore particularly relevant.There is evidence of meaningful differences in the knee adduction moment, flexion moment and flexion angle during walking between

EFORT open reviews2016 Full Text: Link to full Text with Trip Pro

65. Simultaneous anterior cruciate ligament reconstruction and dome-shaped high tibial osteotomy for severe medial compartment osteoarthritis of the knee

Simultaneous anterior cruciate ligament reconstruction and dome-shaped high tibial osteotomy for severe medial compartment osteoarthritis of the knee 29264266 2018 11 13 2214-6873 6 2016 Oct Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology Asia Pac J Sports Med Arthrosc Rehabil Technol Simultaneous anterior cruciate ligament reconstruction and dome-shaped high tibial osteotomy for severe medial compartment osteoarthritis of the knee. 7-12 10.1016/j.asmart (...) .2016.08.001 The optimal surgical procedure to address both anterior cruciate ligament (ACL) deficiency and medial compartment osteoarthritis (OA) has been controversial. A 49-year-old woman with a 30-year history of chronic anterior cruciate ligament (ACL) deficiency, medial compartment osteoarthritis, and varus deformity presented with medial knee pain and apprehension with walking and playing soccer. Her preoperative range of motion was from 0° of extension to 135° of flexion. The anterior drawer sign

Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology2016 Full Text: Link to full Text with Trip Pro

66. Economic Impact of Ketorolac vs Corticosteroid Intra-Articular Knee Injections for Osteoarthritis: A Randomized, Double-Blind, Prospective Study

Economic Impact of Ketorolac vs Corticosteroid Intra-Articular Knee Injections for Osteoarthritis: A Randomized, Double-Blind, Prospective Study 27402605 2016 08 24 2016 08 24 1532-8406 31 9 Suppl 2016 Sep The Journal of arthroplasty J Arthroplasty Economic Impact of Ketorolac vs Corticosteroid Intra-Articular Knee Injections for Osteoarthritis: A Randomized, Double-Blind, Prospective Study. 293-7 10.1016/j.arth.2016.05.015 S0883-5403(16)30153-X Knee osteoarthritis is a disabling disease (...) that costs billions of dollars to treat. Corticosteroid gives varying pain relief and costs $12 per injection, whereas ketorolac costs $2 per injection, per institutional costs. The aim of this study was to compare ketorolac with corticosteroid based on pain relief using patient outcome measures and cost data. A total of 35 patients were randomized to ketorolac or corticosteroid intra-articular knee injection in a double-blind, prospective study. Follow-up was 24 weeks. Osteoarthritis was evaluated using

EvidenceUpdates2016

67. Unloading Shoes for Self-Management of Knee Osteoarthritis: A Randomized Trial.

Unloading Shoes for Self-Management of Knee Osteoarthritis: A Randomized Trial. BACKGROUND: Appropriate footwear is recommended for self-management of knee osteoarthritis. Shoes that reduce harmful knee loads are available, but symptomatic effects are uncertain. OBJECTIVE: To evaluate the efficacy of unloading shoes in alleviating knee osteoarthritis symptoms. DESIGN: Participant- and assessor-blinded comparative effectiveness randomized, controlled trial. (Australian New Zealand Clinical (...) Trials Registry: ACTRN12613000851763). SETTING: Community. PARTICIPANTS: 164 persons with medial knee osteoarthritis. INTERVENTION: Walking shoes with triple-density, variable-stiffness midsoles and mild lateral-wedge insoles designed to unload the medial knee and worn daily (intervention) versus conventional walking shoes (comparator). MEASUREMENTS: Primary outcomes were pain with walking (assessed on a numerical rating scale [NRS]) and physical function (Western Ontario and McMaster Universities

Annals of Internal Medicine2016

68. Exploring Fatigue Trajectories in Early Symptomatic Knee and Hip Osteoarthritis: 6-year Results from the CHECK Study

Exploring Fatigue Trajectories in Early Symptomatic Knee and Hip Osteoarthritis: 6-year Results from the CHECK Study 27182065 2016 07 02 2016 07 02 0315-162X 43 7 2016 Jul The Journal of rheumatology J. Rheumatol. Exploring Fatigue Trajectories in Early Symptomatic Knee and Hip Osteoarthritis: 6-year Results from the CHECK Study. 1413-20 10.3899/jrheum.150820 To examine whether different groups of fatigue trajectories can be identified among patients with early symptomatic osteoarthritis (OA (...) ) of the knee or hip, to describe the level of fatigue severity within each of these fatigue groups, and to investigate the involvement of age, sex, use of medication, comorbidity, and OA severity in relation to group membership. Six years of followup data on fatigue (Medical Outcomes Study Short Form-36 Vitality scale) came from the Cohort Hip and Cohort Knee (CHECK) cohort. Growth mixture modeling was applied to identify distinct fatigue trajectories as well as to take into account the effects

EvidenceUpdates2016

69. Efficacy of Elaeagnus Angustifolia extract in the treatment of knee osteoarthritis: a randomized controlled trial.

Efficacy of Elaeagnus Angustifolia extract in the treatment of knee osteoarthritis: a randomized controlled trial. 27330526 2016 06 22 2016 06 22 2017 02 20 15 2016 EXCLI journal EXCLI J Efficacy of Elaeagnus Angustifolia extract in the treatment of knee osteoarthritis: a randomized controlled trial. 203-10 10.17179/excli2015-639 Osteoarthritis (OA) is one of the most common musculoskeletal disorders all over the world. Available anti-arthritic medications have only partial efficacy (...) and their long-term use is associated with adverse events. Elaeagnus Angustifolia (EA) is a medicinal plant with analgesic and anti-inflammatory properties. The present study evaluated the impact of two doses of EA extract compared with ibuprofen on the severity of disease in patients with knee OA. This study was designed as a randomized, double blind, active-controlled and parallel group trial. Patients with OA were randomized to receive 300 mg/day (n=33) or 600 mg/day (n=32) of EA aqueous extract, or 800

EXCLI journal2016 Full Text: Link to full Text with Trip Pro

70. Physical Therapist-Delivered Pain Coping Skills Training and Exercise for Knee Osteoarthritis: Randomized Controlled Trial

Physical Therapist-Delivered Pain Coping Skills Training and Exercise for Knee Osteoarthritis: Randomized Controlled Trial 26417720 2016 04 27 2016 04 27 2151-4658 68 5 2016 May Arthritis care & research Arthritis Care Res (Hoboken) Physical Therapist-Delivered Pain Coping Skills Training and Exercise for Knee Osteoarthritis: Randomized Controlled Trial. 590-602 10.1002/acr.22744 To investigate whether a 12-week physical therapist-delivered combined pain coping skills training (PCST (...) ) and exercise (PCST/exercise) is more efficacious and cost effective than either treatment alone for knee osteoarthritis (OA). This was an assessor-blinded, 3-arm randomized controlled trial in 222 people (73 PCST/exercise, 75 exercise, and 74 PCST) ages ≥50 years with knee OA. All participants received 10 treatments over 12 weeks plus a home program. PCST covered pain education and training in cognitive and behavioral pain coping skills, exercise comprised strengthening exercises, and PCST/exercise

EvidenceUpdates2016

71. Comparative Effectiveness of Tai Chi Versus Physical Therapy for Knee Osteoarthritis: A Randomized Trial.

Comparative Effectiveness of Tai Chi Versus Physical Therapy for Knee Osteoarthritis: A Randomized Trial. 27183035 2016 07 19 2017 05 01 2017 05 01 1539-3704 165 2 2016 Jul 19 Annals of internal medicine Ann. Intern. Med. Comparative Effectiveness of Tai Chi Versus Physical Therapy for Knee Osteoarthritis: A Randomized Trial. 77-86 10.7326/M15-2143 Few remedies effectively treat long-term pain and disability from knee osteoarthritis. Studies suggest that Tai Chi alleviates symptoms (...) , but no trials have directly compared Tai Chi with standard therapies for osteoarthritis. To compare Tai Chi with standard physical therapy for patients with knee osteoarthritis. Randomized, 52-week, single-blind comparative effectiveness trial. (ClinicalTrials.gov: NCT01258985). An urban tertiary care academic hospital. 204 participants with symptomatic knee osteoarthritis (mean age, 60 years; 70% women; 53% white). Tai Chi (2 times per week for 12 weeks) or standard physical therapy (2 times per week for 6

Annals of Internal Medicine2016

72. Low-dose Spironolactone: Treatment for Osteoarthritis-related Knee Effusion. A Prospective Clinical and Sonographic-based Study

Low-dose Spironolactone: Treatment for Osteoarthritis-related Knee Effusion. A Prospective Clinical and Sonographic-based Study 27036390 2016 06 02 2016 06 02 0315-162X 43 6 2016 Jun The Journal of rheumatology J. Rheumatol. Low-dose Spironolactone: Treatment for Osteoarthritis-related Knee Effusion. A Prospective Clinical and Sonographic-based Study. 1114-20 10.3899/jrheum.151200 To evaluate the effectiveness of spironolactone as a treatment for osteoarthritis (OA)-related knee effusion (...) in comparison to ibuprofen, cold compresses, and placebo. This study was carried out on 200 patients, aged 40 years or older, attending the outpatient clinic of the Rheumatology Department of Sohag University Hospital with unilateral knee effusion related to OA based on clinical examination, musculoskeletal ultrasonography (US), and synovial fluid analysis. In group 1, 50 patients received spironolactone 25 mg daily for 2 weeks; in group 2, 50 patients took ibuprofen 1200 mg daily for 2 weeks; in group 3

EvidenceUpdates2016

73. DMI-9523 (Ampion) for moderate to severe osteoarthritis of the knee

DMI-9523 (Ampion) for moderate to severe osteoarthritis of the knee DMI-9523 (Ampion) for moderate to severe osteoarthritis of the knee DMI-9523 (Ampion) for moderate to severe osteoarthritis of the knee NIHR HSRIC Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation NIHR HSRIC. DMI-9523 (Ampion) for moderate to severe osteoarthritis of the knee. Birmingham: NIHR (...) Horizon Scanning Research&Intelligence Centre. Horizon Scanning Review. 2016 Authors' conclusions Osteoarthritis is the most common type of arthritis in the UK and leads to painful and stiff joints. Osteoarthritis can affect any joint, but commonly affects knee joints. Daily routine activities can become difficult for patients with osteoarthritis of the knee. There is no cure for osteoarthritis of the knee but there are treatments which help to reduce the pain. In cases where treatment does not work

Health Technology Assessment (HTA) Database.2016

74. Feasibility of a Randomized Controlled Trial of Self-Administered Acupressure for Symptom Management in Older Adults with Knee Osteoarthritis.

Feasibility of a Randomized Controlled Trial of Self-Administered Acupressure for Symptom Management in Older Adults with Knee Osteoarthritis. 27031862 2016 05 04 2017 02 06 2017 02 06 1557-7708 22 5 2016 May Journal of alternative and complementary medicine (New York, N.Y.) J Altern Complement Med Feasibility of a Randomized Controlled Trial of Self-Administered Acupressure for Symptom Management in Older Adults with Knee Osteoarthritis. 396-403 10.1089/acm.2015.0231 To assess the feasibility (...) of a study to evaluate the efficacy of self-administered acupressure in pain and related symptom management for older people with symptomatic knee osteoarthritis. Feasibility with regard to (1) sample recruitment and retention, (2) treatment fidelity and adherence, and (3) tolerability and adverse events was examined. The study was a randomized controlled trial. Community-living older adults were recruited and randomly assigned to one of three groups: verum acupressure, sham acupressure, and usual care

Journal of alternative and complementary medicine (New York, N.Y.)2016

75. Effect of Vitamin D Supplementation on Tibial Cartilage Volume and Knee Pain Among Patients With Symptomatic Knee Osteoarthritis: A Randomized Clinical Trial.

Effect of Vitamin D Supplementation on Tibial Cartilage Volume and Knee Pain Among Patients With Symptomatic Knee Osteoarthritis: A Randomized Clinical Trial. 26954409 2016 03 09 2016 03 14 2016 10 17 1538-3598 315 10 2016 Mar 08 JAMA JAMA Effect of Vitamin D Supplementation on Tibial Cartilage Volume and Knee Pain Among Patients With Symptomatic Knee Osteoarthritis: A Randomized Clinical Trial. 1005-13 10.1001/jama.2016.1961 Observational studies suggest that vitamin D supplementation (...) is associated with benefits for knee osteoarthritis, but current trial evidence is contradictory. To compare the effects of vitamin D supplementation vs placebo on knee pain and knee cartilage volume in patients with symptomatic knee osteoarthritis and low vitamin D levels. A multicenter randomized, double-blind, placebo-controlled clinical trial in Tasmania and Victoria, Australia. Participants with symptomatic knee osteoarthritis and low 25-hydroxyvitamin D (12.5-60 nmol/L) were enrolled from June 2010

JAMA2016

76. Randomised controlled trial: NSAIDs or paracetamol for short-term treatment of mild to moderate knee pain in early osteoarthritis: are they equivalent?

Randomised controlled trial: NSAIDs or paracetamol for short-term treatment of mild to moderate knee pain in early osteoarthritis: are they equivalent? NSAIDs or paracetamol for short-term treatment of mild to moderate knee pain in early osteoarthritis: are they equivalent? | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts (...) Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here NSAIDs or paracetamol for short-term treatment of mild to moderate knee pain in early osteoarthritis: are they equivalent? Article Text Therapeutics/Prevention Randomised controlled trial NSAIDs or paracetamol for short-term treatment

Evidence-Based Medicine (Requires free registration)2016

77. Application of an Unloader Knee Brace in the Treatment of Osteoarthritis

Application of an Unloader Knee Brace in the Treatment of Osteoarthritis "Application of an Unloader Knee Brace in the Treatment of Osteoarthrit" by Alexander J. Friedman < > > > > > Title Author Date of Award Summer 8-13-2016 Degree Type Thesis Degree Name Master of Science in Physician Assistant Studies First Advisor AJ Sommers Rights . Abstract BACKGROUND Osteoarthritis (OA) is a debilitating condition that affects a large and diverse cross-section of American society. Historically (...) , treatments for OA have focused on providing symptomatic relief and improving ability to complete activities of daily living (ADLs). These treatments range from NSAID use and physical therapy, to total knee arthroplasty, an invasive and expensive procedure. Although firm data is lacking, many OA patients report subjective symptomatic improvement in symptoms by wearing a knee brace on the affected joint. Recently, several manufacturers have developed a new knee brace designed to reposition the knee

Pacific University EBM Capstone Project2016

78. Nonsurgical Management of Osteoarthritis of the Knee

Nonsurgical Management of Osteoarthritis of the Knee Nonsurgical Management of Osteoarthritis of the Knee | National Guideline Clearinghouse success fail JUL Aug 12 2018 2019 30 Sep 2016 - 13 Jul 2018 COLLECTED BY Organization: Formed in 2009, the Archive Team (not to be confused with the archive.org Archive-It Team) is a rogue archivist collective dedicated to saving copies of rapidly dying or deleted websites for the sake of history and digital heritage. The group is 100% composed (...) In Username or Email * Password * Remember Me Don't have an account? The AHRQ National Guideline Clearinghouse (NGC, guideline.gov) Web site will not be available after July 16, 2018 because federal funding through AHRQ will no longer be available to support the NGC as of that date. For additional information, read our . Guideline Synthesis Nonsurgical Management of Osteoarthritis of the Knee Guidelines Being Compared: American Academy of Orthopaedic Surgeons (AAOS) American Academy of Orthopaedic

National Guideline Clearinghouse (partial archive)2016

79. Taping: knee osteoarthritis

Taping: knee osteoarthritis RACGP - Knee taping for osteoarthritis Username Password Password security changes or call 1800 284 789 Search the RACGP website Your browser has 'Cookies' disabled, alert boxes will continue to appear without this feature. / / / / / Taping: knee osteoarthritis HANDI Making non-drug interventions easier to find and use Taping: knee osteoarthritis Knee OA is the most common cause of knee pain in people older than 50. Intervention Application of strong, adhesive tape (...) or strapping aiming to unload painful soft tissues. Indication Chronic pain related to knee osteoarthritis (OA). Malalignment of the patella, with abnormal distribution of force on the lateral facet, is thought to contribute to pain in knee osteoarthritis. Taping increases patellofemoral contact area, decreasing joint stress and thereby reducing pain. Taping is a very effective pain-relieving strategy and can assist participation in other strongly recommended therapies for knee osteoarthritis, such as

Handbook of Non-Drug interventions (HANDI)2016

80. Walking cane: knee osteoarthritis

Walking cane: knee osteoarthritis RACGP - Walking cane for knee osteoarthritis Username Password Password security changes or call 1800 284 789 Search the RACGP website Your browser has 'Cookies' disabled, alert boxes will continue to appear without this feature. / / / / / Walking cane: knee osteoarthritis HANDI Making non-drug interventions easier to find and use Walking cane: knee osteoarthritis Use of a cane is one of a number of non-drug treatments for knee OA, which include weight (...) reduction, exercise and taping. Intervention Daily use of a walking cane or stick to decrease the load transmitted through the affected knee(s) and improve pain and function. Indication People with knee osteoarthritis (OA) who have pain and difficulty with walking. Precautions recommend that people with bilateral disease should use frames or wheeled walkers rather than canes . A cane is not recommended if people have pre-existing wrist, elbow or shoulder pain on the contralateral side. Canes have

Handbook of Non-Drug interventions (HANDI)2016