Latest & greatest articles for knee osteoarthritis

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This page lists the very latest high quality evidence on knee osteoarthritis and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Top results for knee osteoarthritis

1. Paracetamol versus placebo for knee and hip osteoarthritis. (PubMed)

Paracetamol versus placebo for knee and hip osteoarthritis. BACKGROUND: Paracetamol (acetaminophen) is vastly recommended as the first-line analgesic for osteoarthritis of the hip or knee. However, there has been controversy about this recommendation given recent studies have revealed small effects of paracetamol when compared with placebo. Nonetheless, past studies have not systematically reviewed and appraised the literature to investigate the effects of this drug on specific osteoarthritis (...) sites, that is, hip or knee, or on the dose used. OBJECTIVES: To assess the benefits and harms of paracetamol compared with placebo in the treatment of osteoarthritis of the hip or knee. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials, MEDLINE, Embase, AMED, CINAHL, Web of Science, LILACS, and International Pharmaceutical Abstracts to 3 October 2017, and ClinicalTrials.gov and the World Health Organization International Clinical Trials Registry Platform (ICTRP) portal

2019 Cochrane

2. Could Activity Modifications Indicate Physical Decline Among Adults With Symptomatic Knee Osteoarthritis? (PubMed)

Could Activity Modifications Indicate Physical Decline Among Adults With Symptomatic Knee Osteoarthritis? 28763325 2019 02 14 2019 02 15 1537-7385 97 2 2018 02 American journal of physical medicine & rehabilitation Am J Phys Med Rehabil Could Activity Modifications Indicate Physical Decline Among Adults With Symptomatic Knee Osteoarthritis? 96-103 10.1097/PHM.0000000000000802 Mobility activity modifications indicate early functional losses that act as precursors to future declines among (...) community-dwelling older adults. However, there is scarce evidence on whether activity modifications indicate poorer physical health among adults with symptomatic osteoarthritis, a major cause of disability. Our purpose was to investigate whether patient-reported mobility activity modifications indicated poorer physical health among adults with symptomatic knee osteoarthritis. Secondary cross-sectional analysis of randomized trial data was performed. Preclinical Disability Questionnaire was used

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2019 American journal of physical medicine & rehabilitation

3. Effects of Platelet-Rich Plasma on Pain and Muscle Strength in Patients With Knee Osteoarthritis. (PubMed)

Effects of Platelet-Rich Plasma on Pain and Muscle Strength in Patients With Knee Osteoarthritis. 29210705 2019 02 13 2019 02 15 1537-7385 97 4 2018 04 American journal of physical medicine & rehabilitation Am J Phys Med Rehabil Effects of Platelet-Rich Plasma on Pain and Muscle Strength in Patients With Knee Osteoarthritis. 248-254 10.1097/PHM.0000000000000874 No studies comparing the effects of platelet-rich plasma (PRP) injection and placebo injection in bilateral knee osteoarthritis in the (...) same patient, or discussing muscle strength after PRP injection, have been published. Twenty patients with bilateral knee osteoarthritis were eligible, and 40 knees were randomized into two groups: PRP (knees [right or left by a coin toss] receiving a single intra-articular PRP injection) and saline group (the contralateral knee of the same patient, into which single 4-mL intra-articular injection of normal saline was administered). The primary outcome measure was Western Ontario and McMaster's

2019 American journal of physical medicine & rehabilitation

4. Exercise for osteoarthritis of the knee and risk of subsequent osteoporotic vertebral fractures

Exercise for osteoarthritis of the knee and risk of subsequent osteoporotic vertebral fractures Exercise for osteoarthritis of the knee and subsequent vertebral fracture: An Evidence Snapshot 1 Exercise for osteoarthritis of the knee and risk of subsequent osteoporotic vertebral fractures Citation Garrubba M & Melder A. 2018. Exercise for Osteoarthritis of the knee and risk of subsequent osteoporotic vertebral fractures. Centre for Clinical Effectiveness, Monash Health, Victoria. Contact CCE (...) @monashhealth.org Background The evidence provided in this review aims to support decision-making for the clinical review panel currently investigating a related incident. The review provides evidence about low intensity rehabilitation exercise programs for patients with osteoarthritis of the knee and whether or not participating in exercise increases risk to patients with history of osteoporotic vertebral fractures. Question Does participation in a low intensity rehabilitation exercise program

2019 Monash Health Evidence Reviews

5. Platelet-rich plasma injections for knee osteoarthritis

Platelet-rich plasma injections for knee osteoarthritis Platelet-rich plasma injections for knee Platelet-rich plasma injections for knee osteoarthritis osteoarthritis Interventional procedures guidance Published: 23 January 2019 nice.org.uk/guidance/ipg637 Y Y our responsibility our responsibility This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, healthcare professionals are expected to take (...) #notice-of-rights). Page 1 of 41 1 Recommendations Recommendations 1.1 Current evidence on platelet-rich plasma injections for knee osteoarthritis raises no major safety concerns. However, the evidence on efficacy is limited in quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. 1.2 Clinicians wishing to give platelet-rich plasma injections for knee osteoarthritis should: Inform the clinical governance leads

2019 National Institute for Health and Clinical Excellence - Interventional Procedures

6. Intra-articular Injection of Platelet-Rich Plasma Is Superior to Hyaluronic Acid or Saline Solution in the Treatment of Mild to Moderate Knee Osteoarthritis: A Randomized, Double-Blind, Triple-Parallel, Placebo-Controlled Clinical Trial

Intra-articular Injection of Platelet-Rich Plasma Is Superior to Hyaluronic Acid or Saline Solution in the Treatment of Mild to Moderate Knee Osteoarthritis: A Randomized, Double-Blind, Triple-Parallel, Placebo-Controlled Clinical Trial 30611335 2019 01 06 1526-3231 35 1 2019 Jan Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association Arthroscopy Intra-articular Injection (...) of Platelet-Rich Plasma Is Superior to Hyaluronic Acid or Saline Solution in the Treatment of Mild to Moderate Knee Osteoarthritis: A Randomized, Double-Blind, Triple-Parallel, Placebo-Controlled Clinical Trial. 106-117 S0749-8063(18)30523-1 10.1016/j.arthro.2018.06.035 To prospectively compare the efficacy of intra-articular injections of platelet-rich plasma (PRP) and hyaluronic acid (HA) with a sham control group (normal saline solution [NS]) for knee osteoarthritis in a randomized, dose-controlled

2019 EvidenceUpdates

7. Platelet-Rich Plasma Versus Hyaluronic Acid Injections for the Treatment of Knee Osteoarthritis: Results at 5 Years of a Double-Blind, Randomized Controlled Trial

Platelet-Rich Plasma Versus Hyaluronic Acid Injections for the Treatment of Knee Osteoarthritis: Results at 5 Years of a Double-Blind, Randomized Controlled Trial 30545242 2018 12 14 1552-3365 2018 Dec 13 The American journal of sports medicine Am J Sports Med Platelet-Rich Plasma Versus Hyaluronic Acid Injections for the Treatment of Knee Osteoarthritis: Results at 5 Years of a Double-Blind, Randomized Controlled Trial. 363546518814532 10.1177/0363546518814532 Platelet-rich plasma (PRP (...) controlled trial; Level of evidence, 1. Patients with a history of chronic symptomatic knee degenerative changes and osteoarthritis (Kellgren-Lawrence grade 0-3) were enrolled: 192 patients were randomized to undergo 3 blinded weekly intra-articular injections of either PRP or HA. Patients were prospectively evaluated before the injection and then at 2, 6, 12, and 24 months and a mean of 64.3 months (SD, 7.8 months) of follow-up. Evaluation was based on International Knee Documentation Committee (IKDC

2019 EvidenceUpdates

8. Short-term effects of neuromuscular electrical stimulation and ultrasound therapies on muscle architecture and functional capacity in knee osteoarthritis: a randomized study

Short-term effects of neuromuscular electrical stimulation and ultrasound therapies on muscle architecture and functional capacity in knee osteoarthritis: a randomized study 30514113 2018 12 05 1477-0873 2018 Dec 04 Clinical rehabilitation Clin Rehabil Short-term effects of neuromuscular electrical stimulation and ultrasound therapies on muscle architecture and functional capacity in knee osteoarthritis: a randomized study. 269215518817807 10.1177/0269215518817807 To determine the effects (...) of ultrasound therapy and neuromuscular electrical stimulation (NMES) application on the muscle architecture and functional capacity in patients with knee osteoarthritis. A randomized study. A total of 60 patients with knee osteoarthritis. Participants were randomized into one of the following two intervention groups, five days a week, for three weeks: the combination of NMES application, hot pack, and exercise therapy was applied to the NMES group. The combination of therapeutic ultrasound, hot pack

2019 EvidenceUpdates

9. The efficacy of electromyographic biofeedback on pain, function, and maximal thickness of vastus medialis oblique muscle in patients with knee osteoarthritis: a randomized clinical trial

The efficacy of electromyographic biofeedback on pain, function, and maximal thickness of vastus medialis oblique muscle in patients with knee osteoarthritis: a randomized clinical trial 30519081 2018 12 17 1178-7090 11 2018 Journal of pain research J Pain Res The efficacy of electromyographic biofeedback on pain, function, and maximal thickness of vastus medialis oblique muscle in patients with knee osteoarthritis: a randomized clinical trial. 2781-2789 10.2147/JPR.S169613 The aim (...) of this survey was to examine the effect of adding electromyographic biofeedback (EMGBF) to isometric exercise, on pain, function, thickness, and maximal electrical activity in isometric contraction of the vastus medialis oblique (VMO) muscle in patients with knee osteoarthritis (OA). In this clinical trial, 46 patients with a diagnosis of knee OA were recruited and assigned to two groups. The case group consisted of 23 patients with EMGBF-associated exercise, and the control group was made up of 23 patients

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2019 EvidenceUpdates

10. Association of Pharmacological Treatments With Long-term Pain Control in Patients With Knee Osteoarthritis: A Systematic Review and Meta-analysis. (PubMed)

Association of Pharmacological Treatments With Long-term Pain Control in Patients With Knee Osteoarthritis: A Systematic Review and Meta-analysis. Importance: Even though osteoarthritis is a chronic and progressive disease, pharmacological agents are mainly studied over short-term periods, resulting in unclear recommendations for long-term disease management. Objective: To search, review, and analyze long-term (≥12 months) outcomes (symptoms, joint structure) from randomized clinical trials (...) (RCTs) of medications for knee osteoarthritis. Data Sources and Study Selection: The databases of MEDLINE, Scopus, EMBASE, Web of Science, and the Cochrane Central Register of Controlled Trials were searched until June 30, 2018 (MEDLINE alerts through August 31, 2018) for RCTs of patients with knee osteoarthritis that had treatment and follow-up lasting 1 year or longer. Data Extraction and Synthesis: Data at baseline and at the longest available treatment and follow-up of 12 months' duration

2018 JAMA

11. Intra-articular Mesenchymal Stem Cells in Osteoarthritis of the Knee: A Systematic Review of Clinical Outcomes and Evidence of Cartilage Repair

Intra-articular Mesenchymal Stem Cells in Osteoarthritis of the Knee: A Systematic Review of Clinical Outcomes and Evidence of Cartilage Repair 30455086 2018 11 20 1526-3231 2018 Nov 16 Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association Arthroscopy Intra-articular Mesenchymal Stem Cells in Osteoarthritis of the Knee: A Systematic Review of Clinical Outcomes and Evidence (...) of Cartilage Repair. S0749-8063(18)30616-9 10.1016/j.arthro.2018.07.028 To provide a systematic review of the clinical literature reporting the efficacy of mesenchymal stem cells (MSCs) in terms of clinical outcomes including pain and function and cartilage repair in patients with osteoarthritis. We systematically reviewed any studies investigating clinical outcomes and cartilage repair after the clinical application of cell populations containing MSCs in human subjects with knee osteoarthritis through

2018 EvidenceUpdates

12. Periosteal Electrical Dry Needling as an Adjunct to Exercise and Manual Therapy for Knee Osteoarthritis: A Multicenter Randomized Clinical Trial

Periosteal Electrical Dry Needling as an Adjunct to Exercise and Manual Therapy for Knee Osteoarthritis: A Multicenter Randomized Clinical Trial 29864043 2018 12 11 1536-5409 34 12 2018 Dec The Clinical journal of pain Clin J Pain Periosteal Electrical Dry Needling as an Adjunct to Exercise and Manual Therapy for Knee Osteoarthritis: A Multicenter Randomized Clinical Trial. 1149-1158 10.1097/AJP.0000000000000634 To compare the effects of adding electrical dry needling into a manual therapy (MT (...) ) and exercise program on pain, stiffness, function, and disability in individuals with painful knee osteoarthritis (OA). In total, 242 participants (n=242) with painful knee OA were randomized to receive 6 weeks of electrical dry needling, MT, and exercise (n=121) or MT and exercise (n=121). The primary outcome was related-disability as assessed by the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index at 3 months. Individuals receiving the combination of electrical dry needling, MT

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2018 EvidenceUpdates

13. Clinic-Based Patellar Mobilization Therapy for Knee Osteoarthritis: A Randomized Clinical Trial

Clinic-Based Patellar Mobilization Therapy for Knee Osteoarthritis: A Randomized Clinical Trial 30420367 2018 12 07 1544-1717 16 6 2018 Nov Annals of family medicine Ann Fam Med Clinic-Based Patellar Mobilization Therapy for Knee Osteoarthritis: A Randomized Clinical Trial. 521-529 10.1370/afm.2320 We performed a phase 2 randomized clinical trial to evaluate the preliminary effectiveness of a clinic-based patellar mobilization therapy (PMT) in patients with knee osteoarthritis. We recruited 208 (...) patients with knee osteoarthritis at primary care clinics in Hong Kong. Patients were randomly assigned (1:1) to the intervention group or the control group. The intervention group received 3 PMT treatment sessions from primary care physicians at 2-month intervals, with concomitant prescription of a home-based vastus medialis oblique muscle exercise. The control group received PMT after the study period. The primary outcome was the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC

2018 EvidenceUpdates

14. Structured Education and Neuromuscular Exercise Program for Hip and/or Knee Osteoarthritis

Structured Education and Neuromuscular Exercise Program for Hip and/or Knee Osteoarthritis Public Comment: Held July 19 to August 9, 2018. Structured Education and Neuromuscular Exercise Program for Hip and/or Knee Osteoarthritis: Health Quality Ontario Recommendation FINAL RECOMMENDATION • Health Quality Ontario, under the guidance of the Ontario Health Technology Advisory Committee, recommends publicly funding a structured education and neuromuscular exercise program for the management (...) of people with osteoarthritis of the hip and/or knee RATIONALE FOR THE RECOMMENDATION The Ontario Health Technology Advisory Committee has reviewed the findings of the health technology assessment 1 and concluded that a structured education and neuromuscular exercise program provides clinical benefit in the management of hip and/or knee osteoarthritis and is consistent with patient values and preferences. The Ontario Health Technology Advisory Committee supported data collection and outcome monitoring

2018 Health Quality Ontario

15. Effectiveness of low-dose radiation therapy on symptoms in patients with knee osteoarthritis: a randomised, double-blinded, sham-controlled trial

Effectiveness of low-dose radiation therapy on symptoms in patients with knee osteoarthritis: a randomised, double-blinded, sham-controlled trial 30366945 2018 10 27 1468-2060 2018 Oct 26 Annals of the rheumatic diseases Ann. Rheum. Dis. Effectiveness of low-dose radiation therapy on symptoms in patients with knee osteoarthritis: a randomised, double-blinded, sham-controlled trial. annrheumdis-2018-214104 10.1136/annrheumdis-2018-214104 Low-dose radiation therapy (LDRT) for benign disorders (...) such as knee osteoarthritis (OA) is widely used in some parts of the world, despite absence of controlled studies. We evaluated the effect of LDRT on symptoms and inflammation in patients with knee OA. In this randomised, double-blinded, sham-controlled clinical trial (RCT), we recruited patients with knee OA (clinical ACR criteria) in the Netherlands, aged ≥50 years, pain score ≥5/10 and non-responding to analgesics and exercise therapy. Patients were randomised 1:1 to receive LDRT (1 Gray per fraction

2018 EvidenceUpdates

16. Smoothness of the knee joint movement during the stance phase in patients with severe knee osteoarthritis (PubMed)

Smoothness of the knee joint movement during the stance phase in patients with severe knee osteoarthritis 30202737 2018 11 14 2214-6873 14 2018 Oct Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology Asia Pac J Sports Med Arthrosc Rehabil Technol Smoothness of the knee joint movement during the stance phase in patients with severe knee osteoarthritis. 1-5 10.1016/j.asmart.2018.08.002 Patients with knee osteoarthritis can significantly affect the function (...) jerk value is linked with a decrease in smoothness. However few have reported to evaluate the smoothness of the knee joint movement during walking in patients with knee osteoarthritis. The purpose of the present study was to quantify the smoothness of the knee joint movement during walking in people with knee osteoarthritis. Patients were classified as having early or severe knee osteoarthritis. There were eight patients in each group (16 knees; three males, five females). The normalized angular

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2018 Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology

17. Guideline for the management of knee and hip osteoarthritis

Guideline for the management of knee and hip osteoarthritis racgp.org.au Healthy Profession. Healthy Australia. Guideline for the management of knee and hip osteoarthritis Second editionGuideline for the management of knee and hip osteoarthritis. Second edition Disclaimer The information set out in this publication is current at the date of first publication and is intended for use as a guide of a general nature only and may or may not be relevant to particular patients or circumstances. Nor (...) Practitioners. Guideline for the management of knee and hip osteoarthritis. 2nd edn. East Melbourne, Vic: RACGP , 2018. The Royal Australian College of General Practitioners Ltd 100 Wellington Parade East Melbourne, Victoria 3002 Tel 03 8699 0414 Fax 03 8699 0400 www.racgp.org.au ABN: 34 000 223 807 ISBN: 978-0-86906-500-6 First edition (Guidelines for the non-surgical management of hip and knee osteoarthritis) published 2009 Second edition published July 2018 © The Royal Australian College of General

2018 Clinical Practice Guidelines Portal

18. Is four-week underwater treadmill exercise regimen compared to home exercise efficacious for pain relief and functional improvement in obese patients with knee osteoarthritis? A randomized controlled trial

Is four-week underwater treadmill exercise regimen compared to home exercise efficacious for pain relief and functional improvement in obese patients with knee osteoarthritis? A randomized controlled trial 30064262 2018 08 01 1477-0873 2018 Aug 01 Clinical rehabilitation Clin Rehabil Is four-week underwater treadmill exercise regimen compared to home exercise efficacious for pain relief and functional improvement in obese patients with knee osteoarthritis? A randomized controlled trial (...) . 269215518792041 10.1177/0269215518792041 To investigate the efficacy of a four-week underwater treadmill exercise regimen compared to a home exercise regimen relative to pain relief and functional improvement in obese patients with knee osteoarthritis. Single-blind randomized controlled trial. Outpatient. Eighty primary knee osteoarthritis with pain ⩾5/10 and body mass index ⩾25 kg/m 2 . Daily quadriceps exercise at home for 30 minutes (control group) or underwater treadmill exercise (study group) for 30

2018 EvidenceUpdates

19. Effectiveness and feasibility of acupuncture for knee osteoarthritis: a pilot randomized controlled trial

Effectiveness and feasibility of acupuncture for knee osteoarthritis: a pilot randomized controlled trial 30037276 2018 07 24 1477-0873 2018 Jul 01 Clinical rehabilitation Clin Rehabil Effectiveness and feasibility of acupuncture for knee osteoarthritis: a pilot randomized controlled trial. 269215518790632 10.1177/0269215518790632 To evaluate the effectiveness of acupuncture for pain relief and function improvement in patients with knee osteoarthritis and to determine the feasibility (...) of an eight-week acupuncture intervention. Pilot randomized controlled trial. Three teaching hospitals in China. Patients with knee osteoarthritis (Kellgren grade II or III). Patients were randomly assigned to an eight-week (three sessions per week) intervention of either traditional Chinese acupuncture or sham acupuncture. The primary outcome was response rate-the proportion of patients achieving score ⩾36% decrease in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain

2018 EvidenceUpdates

20. Knee osteoarthritis

Knee osteoarthritis Top results for knee osteoarthritis - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box (...) and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for knee osteoarthritis The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical

2018 Trip Latest and Greatest