Newer hypnotic drugs for the short-term management of insomnia: a systematic review and economic evaluation Newer hypnotic drugs for the short-term management of insomnia: a systematic review and economic evaluation Newer hypnotic drugs for the short-term management of insomnia: a systematic review and economic evaluation Dundar Y, Boland A, Strobl J, Dodd S, Haycox A, Bagust A, Bogg J, Dickson R, Walley T CRD summary This review compared zaleplon, zolpidem and zopiclone with benzodiazepines (...) (licensed and used in the UK) for the short-term management of insomnia. The authors concluded that short-acting drugs (Z-drugs) seemed equally effective and safe, but that there was a clear need for further research in this area. The authors suggested interpreting the findings with considerable caution, and their recommendation for further research seems appropriate. Authors' objectives To compare the clinical and cost-effectiveness of zaleplon, zolpidem and zopiclone with benzodiazepines for the short

Guidance on the use of zaleplon, zolpidem and zopiclone for the short-term management of insomnia (TA77) Overview | Guidance on the use of zaleplon, zolpidem and zopiclone for the short-term management of insomnia | Guidance | NICE Guidance on the use of zaleplon, zolpidem and zopiclone for the short-term management of insomnia Technology appraisal guidance [TA77] Published date: 28 April 2004 Share Save Guidance on zolpidem and zopiclone for treating insomnia in adults. The recommendations

Psychological treatment for insomnia in the regulation of long-term hypnotic drug use Psychological treatment for insomnia in the regulation of long-term hypnotic drug use Journals Library An error has occurred in processing the XML document An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information

Effects of acupuncture therapy on insomnia Effects of acupuncture therapy on insomnia Effects of acupuncture therapy on insomnia Sok S R, Erlen J A, Kim K B CRD summary This review assessed the effects of acupuncture therapy on insomnia. The authors concluded that acupuncture may be an effective intervention for insomnia. A number of methodological problems, both in the included studies and in the review, mean that this conclusion may not be reliable. Authors' objectives To assess the trends (...) across acupuncture studies for insomnia, to examine dependent variables, and to evaluate the effects of acupuncture therapy on insomnia in older people. Only the latter objective is discussed in this abstract. Searching MEDLINE, AMED, all EBM reviews (i.e. Cochrane Database of Systematic Reviews, ACP Journal Club, DARE and the Cochrane Controlled Trials Register), MANTIS, CINAHL, AIDSLINE, PsycINFO, International Pharmaceutical Abstracts, BIOETHICSLINE, Cancerlit, HealthSTAR and SPORTDiscus were

Psychological treatment for insomnia in the management of long-term hypnotic drug use: a pragmatic randomised controlled trial Psychological treatment for insomnia in the management of long-term hypnotic drug use: a pragmatic randomised controlled trial Psychological treatment for insomnia in the management of long-term hypnotic drug use: a pragmatic randomised controlled trial Morgan K, Dixon S, Mathers N, Thompson J, Tomeny M Record Status This is a critical abstract of an economic evaluation (...) that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Patients with chronic sleep problems, who had been using hypnotic drugs for at least 1 month, were given a course of cognitive-behaviour therapy (CBT) to help with their insomnia. The CBT consisted of 6 sessions with a practice counsellor specially trained

Comparative meta-analysis of pharmacotherapy and behavior therapy for persistent insomnia Comparative meta-analysis of pharmacotherapy and behavior therapy for persistent insomnia Comparative meta-analysis of pharmacotherapy and behavior therapy for persistent insomnia Smith M T, Perlis M L, Park A, Smith M S, Pennington J, Giles D E, Buysse D J Authors' objectives To conduct a quantitative review of the literature to compare the short-term efficacy of pharmacotherapy and behavioural therapy (...) in primary insomnia. Searching MEDLINE and PsycINFO were searched from 1966 to 2000 for publications in the English language, using the keywords 'insomnia' and 'treatment'. Published studies were also identified from the bibliographies provided by the authors of two meta-analyses of insomnia (see Other Publications of Related Interest nos.1-2). Study selection Study designs of evaluations included in the review Only studies in which within-subject measurements were obtained before and after treatment

Melatonin in elderly patients with insomnia: a systematic review Melatonin in elderly patients with insomnia: a systematic review Melatonin in elderly patients with insomnia: a systematic review Olde Rikkert M G, Rigaud A S Authors' objectives To determine the efficacy of melatonin in elderly insomniacs. Searching The Cochrane Controlled Trials Register and MEDLINE were searched from 1990 to 2000 using the terms 'melatonin', 'geriatrics' and '(frail)-elderly'. The references from identified (...) in selected elderly insomniacs. However, there was insufficient evidence to warrant regular prescription of melatonin in elderly insomniacs, especially in the case of co-morbidity. CRD commentary The aims were stated and the inclusion criteria were defined in terms of the study design, intervention and participants. The inclusion criteria were not defined a priori in terms of the outcome, and no predetermined criteria were used to define insomnia. Two relevant literature sources were searched

Cognitive behavioral therapy for treatment of chronic primary insomnia: a randomized controlled trial. Use of nonpharmacological behavioral therapy has been suggested for treatment of chronic primary insomnia, but well-blinded, placebo-controlled trials demonstrating effective behavioral therapy for sleep-maintenance insomnia are lacking.To test the efficacy of a hybrid cognitive behavioral therapy (CBT) compared with both a first-generation behavioral treatment and a placebo therapy (...) for treating primary sleep-maintenance insomnia.Randomized, double-blind, placebo-controlled clinical trial conducted at a single academic medical center, with recruitment from January 1995 to July 1997.Seventy-five adults (n = 35 women; mean age, 55.3 years) with chronic primary sleep-maintenance insomnia (mean duration of symptoms, 13.6 years).Patients were randomly assigned to receive CBT (sleep education, stimulus control, and time-in-bed restrictions; n = 25), progressive muscle relaxation training

Valerian for insomnia: a systematic review of randomized clinical trials Valerian for insomnia: a systematic review of randomized clinical trials Valerian for insomnia: a systematic review of randomized clinical trials Stevinson C, Ernst E Authors' objectives To review the evidence for the effects of the herb valerian on insomnia. Searching A range of electronic databases was searched from their inception to May 1999, and the reference lists of retrieved papers were checked for further (...) effects of valerian administered over consecutive days, whilst six measured acute responses to single doses. The doses ranged from 60 to 1,215 mg/day. Participants included in the review No inclusion criteria were stated in terms of the participants. The participants included chronically ill patients in geriatric hospitals for whom difficulty in sleeping was one of a number of complaints, elderly female poor sleepers, patients with non-organic insomnia who were not suffering from depression, mild

Meta-analysis of benzodiazepine use in the treatment of insomnia Meta-analysis of benzodiazepine use in the treatment of insomnia Meta-analysis of benzodiazepine use in the treatment of insomnia Holbrook A M, Crowther R, Lotter A, Cheng C, King D Authors' objectives To systematically review the benefits and risks associated with the use of benzodiazepines to treat insomnia in adults. Searching MEDLINE was searched from 1966 to December 1998 using the MeSH terms 'bezodiazepine' (exploded (...) . The comparator active treatments included zopiclone, diphenhydramine, glutethimide and promethazine as well as one non-pharmacological intervention (behavioural therapy). Participants included in the review Patients suffering from insomnia. Various patient exclusion criteria were applied within individual studies (not all applied in all studies). These exclusion criteria were: those who were receiving or had recently undergone treatment for insomnia; those who had ever been diagnosed with a psychiatric

Nonpharmacologic treatment of chronic insomnia Nonpharmacologic treatment of chronic insomnia Nonpharmacologic treatment of chronic insomnia Morin C M, Hauri P J, Espie C A, Spielman A J, Buysse D J, Bootzin R R Authors' objectives To assess the efficacy of non-pharmacological treatments for primary chronic insomnia. Searching PsycLIT and MEDLINE were searched from 1970 to 1997 using the following keywords: insomnia, nonpharmacological-nondrug, behavior-cognitive-psychological and treatment (...) and female) whose primary diagnosis was insomnia were included. Studies composed predominately of college students were excluded. Insomnia may involve problems falling asleep, problems staying asleep, or early morning wakening with an inability to resume sleep. Outcomes assessed in the review Sleep onset latency, number and/or duration of awakening, total sleep time, and sleep quality were assessed. How were decisions on the relevance of primary studies made? The authors do not state how the papers were

Tolerance and rebound insomnia with rapidly eliminated hypnotics: a meta-analysis of sleep laboratory studies Tolerance and rebound insomnia with rapidly eliminated hypnotics: a meta-analysis of sleep laboratory studies Tolerance and rebound insomnia with rapidly eliminated hypnotics: a meta-analysis of sleep laboratory studies Soldatos C R, Dikeos D G, Whitehead A Authors' objectives To determine whether there are differences in initial efficacy, development of tolerance and occurrence (...) of rebound insomnia between rapidly eliminated hypnotics (brotizolam, midazolam, triazolam, zolpidem and zopiclone). Searching MEDLINE was searched from 1966 to April 1997 using the generic names of the drugs as keywords, i.e. 'brotizolam', 'midazolam', 'triazolam', 'zolpidem' and 'zopiclone'. Additional references were obtained by examining the bibliographies of retrieved papers, and by contacting pharmaceutical manufacturers. Abstracts of all available publications were scanned visually to identify

Behavioral and pharmacological therapies for late-life insomnia: a randomized controlled trial. Insomnia is a prevalent health complaint in older adults. Behavioral and pharmacological treatments have their benefits and limitations, but no placebo-controlled study has compared their separate and combined effects for late-life insomnia.To evaluate the clinical efficacy of behavioral and pharmacological therapies, singly and combined, for late-life insomnia.Randomized, placebo-controlled clinical (...) for the short-term management of insomnia in late life; sleep improvements are better sustained over time with behavioral treatment.

Benzodiazepines and zolpidem for chronic insomnia: a meta-analysis of treatment efficacy. To evaluate the efficacy of benzodiazepines and zolpidem tartrate in chronic insomnia based on a quantitative review of literature.Articles from 1966 to 1996 were identified using MEDLINE, by a manual review of relevant journals, and from bibliographies of identified articles.Studies using randomized, double-blind, placebo-controlled, parallel or crossover designs with benzodiazepines or zolpidem in adults (...) younger than 65 years with chronic insomnia (modified Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for primary insomnia) were selected for review. Self-report and polysomnographic measures of sleep-onset latency, total sleep time, number of awakenings, and sleep quality were selected as outcomes.Twenty-two studies met the selection criteria. A combined test of Pvalues was performed, pooling broadly from the 22 studies to determine whether medication was superior

Nonpharmacological interventions for insomnia in older adults: a meta-analysis of treatment efficacy Nonpharmacological interventions for insomnia in older adults: a meta-analysis of treatment efficacy Nonpharmacological interventions for insomnia in older adults: a meta-analysis of treatment efficacy Pallesen S, Nordhus I H, Kvale G Authors' objectives To examine the effects of non-pharmacological interventions for insomnia in the elderly. Searching Computer searches were conducted of PsycLIT (...) in the review Participants whose target problem was sleep onset, maintenance or mixed insomnia and who had a minimum age of 50 years with study mean age exceeding 60 years were included. Outcomes assessed in the review Outcome measures included at minimum self reports of sleep onset latency (SOL) awakening after sleep onset (WASO), and number of awakenings or total sleep time (TST). Both immediate posttreatment effects and long term effects taken on average 6 months following treatment were evaluated. Self

Benzodiazepines and zolpidem for chronic insomnia: a meta-analysis of treatment efficacy Benzodiazepines and zolpidem for chronic insomnia: a meta-analysis of treatment efficacy Benzodiazepines and zolpidem for chronic insomnia: a meta-analysis of treatment efficacy Nowell P D, Mazumdar S, Buysse D J, Dew M A, Reynolds C F, Kupfer D J Authors' objectives To assess the efficacy of benzodiazepines and zolpidem for chronic insomnia. Searching MEDLINE was searched from 1966 to 1996. Current (...) Contents was also searched and references cited in reports were obtained. The search strategy used the subject heading 'insomnia' with the subheading 'drug therapy' combined with 'placebos'. The Journal of Sleep Research was handsearched up to 1995. Only published studies were included. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs) that included placebo groups and double-blinded assessment of the outcomes. Crossover designs were included

Identifying effective psychological treatments for insomnia: a meta-analysis Identifying effective psychological treatments for insomnia: a meta-analysis Identifying effective psychological treatments for insomnia: a meta-analysis Murtagh D R, Greenwood K M Authors' objectives To provide practical direction for the treatment of insomnia by investigating the following: the effectiveness of psychological treatments compared with each other and with a placebo, to determine the most effective (...) treatments for the various symptoms of insomnia over short- and long-term periods, to assess the patient and treatment variables that have most influence on outcome, and to determine how effect sizes are related to systematic differences in study methodology. Searching PsycLIT and MEDLINE were searched from 1973 to 1993 for articles published in the English language using the keyword 'insomnia', and the reference lists of relevant review articles and books were examined. Unpublished studies were

Integration of Behavioral and Relaxation Approaches Into the Treatment of Chronic Pain and Insomnia 37 Integration of Behavioral and Relaxation Approaches into the Treatment of Chronic Pain and Insomnia National Institutes of Health Technology Assessment Conference Statement October 16–18, 1995 NATIONAL INSTITUTES OF HEALTH Office of the Director 35 About the NIH Technology Assessment Program NIH Technology Assessment Conferences and Workshops are convened to evaluate available scientific (...) bibliographic reference to this technology assessment statement, it is recommended that the following format be used, with or without source abbreviations, but without authorship attribution: Integration of Behavioral and Relaxation Approaches into the Treatment of Chronic Pain and Insomnia. NIH Technol Assess Statement 1995 Oct 16–18; 1-34. Publications Ordering Information NIH Consensus Statements, NIH Technology Assessment Statements, and related materials are available by writing to the NIH Consensus

Nonpharmacological interventions for insomnia: a meta-analysis of treatment efficacy Nonpharmacological interventions for insomnia: a meta-analysis of treatment efficacy Nonpharmacological interventions for insomnia: a meta-analysis of treatment efficacy Morin C M, Culbert J P, Schwartz S M Authors' objectives To examine the efficacy and durability of psychological treatments for the clinical management of chronic insomnia. Searching A computer search was carried out (database not specified (...) in bed to the actual amount of sleep); relaxation therapies (e.g. muscle relaxation, biofeedback, meditation to alleviate somatic or cognitive arousal); paradoxical intention (persuasion of patient to engage in their most feared behaviour - staying awake -to induce sleep); and sleep hygiene education (regulation of health and environmental factors that may be detrimental or beneficial to sleep). Participants included in the review Patients with either sleep-onset, maintenance or mixed insomnia