Latest & greatest articles for insomnia

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on insomnia or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on insomnia and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for insomnia

81. A retrospective analysis on patients at high‐risk for obstructive sleep apnea undergoing ear, nose, and throat surgeries Full Text available with Trip Pro

A retrospective analysis on patients at high‐risk for obstructive sleep apnea undergoing ear, nose, and throat surgeries Obstructive sleep apnea (OSA) may be related to episodes of oxygen de-saturation, hypercapnia, cardiovascular dysfunction, cor-pulmonale, and pulmonary hypertension. STOP-BANG is an acronym for eight specific questions used to assess the likelihood of OSA. If the individual exhibits three or more of these indicators, he/she should be considered to be at high risk for OSA

2017 Laryngoscope investigative otolaryngology

82. Conventional Polysomnography Is Not Necessary for the Management of Most Patients with Suspected Obstructive Sleep Apnea. Noninferiority, Randomized Controlled Trial (Abstract)

Conventional Polysomnography Is Not Necessary for the Management of Most Patients with Suspected Obstructive Sleep Apnea. Noninferiority, Randomized Controlled Trial Home respiratory polygraphy may be a simpler alternative to in-laboratory polysomnography for the management of more symptomatic patients with obstructive sleep apnea, but its effectiveness has not been evaluated across a broad clinical spectrum.To compare the long-term effectiveness (6 mo) of home respiratory polygraphy (...) and polysomnography management protocols in patients with intermediate-to-high sleep apnea suspicion (most patients requiring a sleep study).A multicentric, noninferiority, randomized controlled trial with two open parallel arms and a cost-effectiveness analysis was performed in 12 tertiary hospitals in Spain. Sequentially screened patients with sleep apnea suspicion were randomized to respiratory polygraphy or polysomnography protocols. Moreover, both arms received standardized therapeutic decision-making

2017 EvidenceUpdates

83. Hypoglossal nerve stimulation for moderate to severe obstructive sleep apnoea

Hypoglossal nerve stimulation for moderate to severe obstructive sleep apnoea Hypoglossal nerv Hypoglossal nerve stimulation for moder e stimulation for moderate to ate to se sev vere obstructiv ere obstructive sleep apnoea e sleep apnoea Interventional procedures guidance Published: 22 November 2017 nice.org.uk/guidance/ipg598 Y Y our responsibility our responsibility This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising (...) of hypoglossal nerve stimulation for moderate to severe obstructive sleep apnoea is limited in quantity and quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent and audit or research. © NICE 2018. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 1 of 81.2 Clinicians wishing to do hypoglossal nerve stimulation for moderate to severe obstructive sleep apnoea should: Inform

2017 National Institute for Health and Clinical Excellence - Interventional Procedures

84. Autoadjusted versus fixed CPAP for obstructive sleep apnoea: a multicentre, randomised equivalence trial (Abstract)

Autoadjusted versus fixed CPAP for obstructive sleep apnoea: a multicentre, randomised equivalence trial The obstructive sleep apnoea syndrome (OSAS) is conventionally treated by continuous positive airway pressure set at a fixed level (fCPAP). Automatic mask pressure adjustment (autoCPAP) is increasingly used during home therapy. We investigated whether autoCPAP is equivalent to fCPAP in improving sleepiness in patients with OSAS in the long-term.In this multicentre equivalence trial, 208 (...) patients with OSAS, with median Epworth sleepiness score (ESS) 13, apnoea/hypopnoea index 48.4/hour, were randomised to treatment with autoCPAP (5-15 mbar) or fCPAP (pressure set at the 90th percentile applied by autoCPAP during 2-4 weeks adaptation). Coprimary outcomes were changes in subjective and objective sleepiness from baseline to 2 years after treatment. Equivalence ranges were ±2 points in ESS and ±3 min sleep resistance time evaluated by recording responses to light signals.At 2 years

2017 EvidenceUpdates

85. Effect of continuous positive airway pressure on blood pressure and metabolic profile in women with sleep apnoea Full Text available with Trip Pro

Effect of continuous positive airway pressure on blood pressure and metabolic profile in women with sleep apnoea Continuous positive airway pressure (CPAP) reduces blood pressure levels in hypertensive patients with obstructive sleep apnoea (OSA). However, the role of CPAP in blood pressure and the metabolic profile in women has not yet been assessed. In this study we investigated the effect of CPAP on blood pressure levels and the glucose and lipid profile in women with moderate-to-severe (...) OSA.A multicentre, open-label, randomised controlled trial was conducted in 307 women diagnosed with moderate-to-severe OSA (apnoea-hypopnoea index ≥15 events·h-1) in 19 Spanish Sleep Units. Women were randomised to CPAP (n=151) or conservative treatment (n=156) for 12 weeks. Changes in office blood pressure measures as well as in the glucose and lipid profile were assessed in both groups.Compared with the control group, the CPAP group achieved a significantly greater decrease in diastolic blood

2017 EvidenceUpdates

86. Uncertainty of screening tools for obstructive sleep apnea in asymptomatic adults with treatments varying in effects

* Associated Topics Uncertainty of screening tools for obstructive sleep apnea in asymptomatic adults with treatments varying in effects Linda L. Cheng, DDS, FAGD, ABGD . Overview Systematic Review Conclusion Limited, inconclusive evidence exists on the accuracy or clinical utility of screening tools for obstructive sleep apnea (OSA) in adults who are asymptomatic or who may have unrecognized signs of OSA. Various OSA treatments may reduce apnea-hypopnea index (AHI), Epworth Sleepiness Scale (ESS) scores (...) Uncertainty of screening tools for obstructive sleep apnea in asymptomatic adults with treatments varying in effects Uncertainty of screening tools for obstructive sleep apnea in asymptomatic adults with treatments varying in effects ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all

2017 ADA Center for Evidence-Based Dentistry

87. Uncertainty of screening tools for obstructive sleep apnea in asymptomatic adults with treatments varying in effects

* Associated Topics Uncertainty of screening tools for obstructive sleep apnea in asymptomatic adults with treatments varying in effects Linda L. Cheng, DDS, FAGD, ABGD . Overview Systematic Review Conclusion Limited, inconclusive evidence exists on the accuracy or clinical utility of screening tools for obstructive sleep apnea (OSA) in adults who are asymptomatic or who may have unrecognized signs of OSA. Various OSA treatments may reduce apnea-hypopnea index (AHI), Epworth Sleepiness Scale (ESS) scores (...) Uncertainty of screening tools for obstructive sleep apnea in asymptomatic adults with treatments varying in effects Uncertainty of screening tools for obstructive sleep apnea in asymptomatic adults with treatments varying in effects ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all

2017 ADA Center for Evidence-Based Dentistry

88. Uncertainty of screening tools for obstructive sleep apnea in asymptomatic adults with treatments varying in effects

* Associated Topics Uncertainty of screening tools for obstructive sleep apnea in asymptomatic adults with treatments varying in effects Linda L. Cheng, DDS, FAGD, ABGD . Overview Systematic Review Conclusion Limited, inconclusive evidence exists on the accuracy or clinical utility of screening tools for obstructive sleep apnea (OSA) in adults who are asymptomatic or who may have unrecognized signs of OSA. Various OSA treatments may reduce apnea-hypopnea index (AHI), Epworth Sleepiness Scale (ESS) scores (...) Uncertainty of screening tools for obstructive sleep apnea in asymptomatic adults with treatments varying in effects Uncertainty of screening tools for obstructive sleep apnea in asymptomatic adults with treatments varying in effects ADA Websites Access news, member benefits and ADA policy Attend ADA's premier event Access cutting-edge continuing education courses Find evidence to support your clinical decisions Access member-only practice content Investing in better oral health for all

2017 ADA Center for Evidence-Based Dentistry

89. Treatments for Insomnia: A Review of Patient and Experiences and Perspectives

care, patients, sleep initiation and maintenance disorders, Caregiver, caregivers, patient, families, insomniac, insomniacs, Qualitative, patient centered care Files Rapid Response Peer-Reviewed Summary with Critical Appraisal Published : September 27, 2017 Related Content Follow us: © 2019 Canadian Agency for Drugs and Technologies in Health Get our newsletter: (...) of medical sleeping aids. While the duration and intensity of insomnia also plays a role, this review was unable to identify any consistent timeframes or severity levels that could serve as indicators. Rather, the use of pharmacotherapy tends to be informed by a certain level of pragmatism balancing need with desired outcomes. For instance, while several individuals perceived pharmacotherapy as the better choice due to its rapid relief, others were concerned with daytime side-effects and issues of long

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

90. Trajectories of change and long-term outcomes in a randomised controlled trial of internet-based insomnia treatment to prevent depression Full Text available with Trip Pro

of CBT-I emerged; evidence for distinct trajectories of change in depressive symptoms; and predictors of these trajectories.A randomised controlled trial compared the 6-week Sleep Healthy Using the Internet (SHUTi) CBT-I program to an attention control program. Adults (N=1149) with clinical insomnia and subclinical depression symptoms were recruited online from the Australian community.Depression, anxiety and insomnia decreased significantly by week 4 of the intervention period and remained (...) Trajectories of change and long-term outcomes in a randomised controlled trial of internet-based insomnia treatment to prevent depression Insomnia treatment using an internet-based cognitive-behavioural therapy for insomnia (CBT-I) program reduces depression symptoms, anxiety symptoms and suicidal ideation. However, the speed, longevity and consistency of these effects are unknown.To test the following: whether the efficacy of online CBT-I was sustained over 18 months; how rapidly the effects

2017 BJPsych open Controlled trial quality: uncertain

91. Risk of Obstructive Sleep Apnea and Its Association with Cardiovascular and Noncardiac Vascular Risk in Patients with Rheumatoid Arthritis: A Population-based Study Full Text available with Trip Pro

Risk of Obstructive Sleep Apnea and Its Association with Cardiovascular and Noncardiac Vascular Risk in Patients with Rheumatoid Arthritis: A Population-based Study To define the incidence of obstructive sleep apnea (OSA) in patients with rheumatoid arthritis (RA) and determine whether OSA diagnosis predicts future cardiovascular disease (CVD) and noncardiac vascular events.Medical information pertaining to RA, OSA, CVD, and vascular diagnoses was extracted from a comprehensive medical record

2017 EvidenceUpdates

92. SA-237 for neuromyelitis optica and neuromyelitis optica spectrum disorders

SA-237 for neuromyelitis optica and neuromyelitis optica spectrum disorders SA-237 for neuromyelitis optica and neuromyelitis optica spectrum disorders | Innovation Observatory toggle menu Menu Search View All Filter by Speciality Filter by Year Filter by Category This search function provides links to outputs produced by NIHR Innovation Observatory. These are briefing notes or reports on new or repurposed technologies. This search will not return all technologies currently in development (...) as these outputs are produced as required for our stakeholders. > > > SA-237 for neuromyelitis optica and neuromyelitis optica spectrum disorders SA-237 for neuromyelitis optica and neuromyelitis optica spectrum disorders August 2017 Neuromyelitis optica (Devic’s disease) is a rare autoimmune disorder (a condition where the immune system attacks itself). It is characterised by the inflammation of the nerve that leads from the eye to the brain, and the spinal cord. Symptoms consist of vision loss, loss

2017 NIHR Innovation Observatory

93. Friedman tongue position and cone beam computed tomography in patients with obstructive sleep apnea Full Text available with Trip Pro

Friedman tongue position and cone beam computed tomography in patients with obstructive sleep apnea Evaluate the correlation between Friedman Tongue Position (FTP) and airway cephalometrics in patients with obstructive sleep apnea (OSA).Retrospective review of adult patients with OSA undergoing Cone Beam Computed Tomography (CBCT).Collected data included age, sex, body mass index, apnea hypopnea index, FTP, and airway cephalometric parameters. Data analyses were performed using ANOVA

2017 Laryngoscope investigative otolaryngology

94. Management of Insomnia Disorder in Adults: Current State of the Evidence

use. These include nonbenzodiazepine hypnotics (zaleplon, zolpidem, eszopiclone), an orexin receptor antagonist (suvorexant), a melatonin agonist (ramelteon), some benzodiazepines (e.g., triazolam, temazepam), and an antidepressant (doxepin). The systematic review assessed the efficacy , comparative effectiveness, and adverse effects of a broad range of management strategies for insomnia disorder in adults. 1. American Psychiatric Association. Sleep-wake disorders. In: Diagnostic and Statistical (...) through January 2015. The full report, listing all studies, is available at www.effectivehealthcare.ahrq.gov/insomnia/. This summary is provided to assist in informed clinical decisionmaking. However, reviews of evidence should not be construed to represent clinical recommendations or guidelines. Background Insomnia involves dissatisfaction with sleep quantity or quality and is associated with difficulty initiating sleep, maintaining sleep, returning to sleep after early morning waking

2017 Effective Health Care Program (AHRQ)

95. Cognitive behavioral therapy for insomnia in Parkinson’s disease: a case series Full Text available with Trip Pro

). Parkinson's disease patients who had undergone a baseline and at least one follow-up CBTi session were identified. Electronic medical records and pre-treatment and post-treatment patient sleep diaries were reviewed. Sleep measures of interest included wake time after sleep onset, sleep efficiency, sleep onset latency, and total sleep time. Pre-treatment and post-treatment values were compared within subjects using paired t-test. Five patients were included. Patients attended an average of eight sessions (...) of CBTi (range 5-12). Significant increases in sleep efficiency (p = 0.02) and decreases in number of awakenings per night (p = 0.02) were found. Our data provide preliminary evidence that cognitive behavioral therapy is an effective treatment for insomnia in Parkinson's disease, and is well tolerated and well received by patients. Given the limited data supporting use of medications to treat chronic insomnia in Parkinson's disease, combined with their risks, randomized trials to demonstrate

2017 NPJ Parkinson's disease

96. Tai Chi Chih Compared With Cognitive Behavioral Therapy for the Treatment of Insomnia in Survivors of Breast Cancer: A Randomized, Partially Blinded, Noninferiority Trial Full Text available with Trip Pro

trial that involved survivors of breast cancer with insomnia who were recruited from the Los Angeles community from April 2008 to July 2012. After a 2-month phase-in period with repeated baseline assessment, participants were randomly assigned to 3 months of CBT-I or TCC and evaluated at months 2, 3 (post-treatment), 6, and 15 (follow-up). Primary outcome was insomnia treatment response-that is, marked clinical improvement of symptoms by the Pittsburgh Sleep Quality Index-at 15 months. Secondary (...) outcomes were clinician-assessed remission of insomnia; sleep quality; total sleep time, sleep onset latency, sleep efficiency, and awake after sleep onset, derived from sleep diaries; polysomnography; and symptoms of fatigue, sleepiness, and depression. Results Of 145 participants who were screened, 90 were randomly assigned (CBT-I: n = 45; TCC: n = 45). The proportion of participants who showed insomnia treatment response at 15 months was 43.7% and 46.7% in CBT-I and TCC, respectively. Tests

2017 EvidenceUpdates

97. Medical Cannabis or Cannabinoids for the Treatment of Insomnia Disorder in Adults: Clinical Effectiveness and Guidelines

study were identified regarding the use of medical cannabis or cannabinoids in the treatment of insomnia disorder in adults. Tags cannabidiol, cannabinoids, cannabis, insomnia, marihuana, marijuana, mental health, sleep disorders, sleep initiation and maintenance disorders, sleeplessness, Cannabinoid, insomniac, insomniacs, sleep dysfunction Files Rapid Response Summary of Abstracts Published : June 26, 2017 Related Content Follow us: © 2019 Canadian Agency for Drugs and Technologies in Health Get (...) Medical Cannabis or Cannabinoids for the Treatment of Insomnia Disorder in Adults: Clinical Effectiveness and Guidelines Medical Cannabis or Cannabinoids for the Treatment of Insomnia Disorder in Adults: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Medical Cannabis or Cannabinoids for the Treatment of Insomnia Disorder in Adults: Clinical Effectiveness and Guidelines Medical Cannabis or Cannabinoids for the Treatment of Insomnia Disorder in Adults: Clinical

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

98. Current Practice Analysis: Interventions for Insomnia Disorder

sleep hygiene, sleep consolidation, stimulus control, and relaxation therapies. Cognitive techniques include cognitive behavioural therapy for insomnia (CBT-I). 1,7 Psychotherapies may be used in combination with pharmacotherapy for enhanced effectiveness. 8 Objective The objective of this study was to explore current trends across Canada in the use of interventions for the treatment of insomnia disorder. We surveyed primary care providers for their opinions and prescribing preferences when treating (...) for patients with insomnia disorder (Table 8). All FPs surveyed (100%) indicated that they would prescribe behavioural therapies for their patients. Of these behavioural therapies, sleep hygiene (98%) and relaxation training (73%) were the most popular choices. Mindfulness (43%), CBT-I (29%), and sleep restriction were also cited. Drug therapies were the second most popular intervention overall for patients with insomnia among 99% of FPs surveyed. FPs indicated that they had experience prescribing

2017 CADTH - Optimal Use

99. Transoral robotic surgery vs. endoscopic partial midline glossectomy for obstructive sleep apnea Full Text available with Trip Pro

Transoral robotic surgery vs. endoscopic partial midline glossectomy for obstructive sleep apnea To compare sleep-related outcomes in obstructive sleep apnea hypopnea syndrome (OSAHS) patients following base of tongue resection via robotic surgery and endoscopic midline glossectomy.This was a retrospective study. A total of 114 robotic and 37 endoscopic midline glossectomy surgeries were performed between July 2010 and April 2015 as part of single or multilevel surgery. Patients were excluded (...) for indications other than sleep apnea or if complete sleep studies were not obtained. Thus, 45 robotic and 16 endoscopic surgeries were included in the analysis.In the robotic surgery group there were statistically significant improvements in AHI [(44.4 ± 22.6) events/h-(14.0 ± 3.0) events/h, P < 0.001] Epworth Sleepiness Scale (12.3 ± 4.6 to 4.5 ± 2.9, P < 0.001), and O2 nadir (82.0% ± 6.1% to 85.0% ± 5.4%, P < 0.001). In the endoscopic group there were also improvements in AHI (48.7 ± 30.2 to 27.4 ± 31.9

2017 World journal of otorhinolaryngology - head and neck surgery

100. Current Practice Analysis: Interventions for Insomnia Disorder

sleep hygiene, sleep consolidation, stimulus control, and relaxation therapies. Cognitive techniques include cognitive behavioural therapy for insomnia (CBT-I). 1,7 Psychotherapies may be used in combination with pharmacotherapy for enhanced effectiveness. 8 Objective The objective of this study was to explore current trends across Canada in the use of interventions for the treatment of insomnia disorder. We surveyed primary care providers for their opinions and prescribing preferences when treating (...) for patients with insomnia disorder (Table 8). All FPs surveyed (100%) indicated that they would prescribe behavioural therapies for their patients. Of these behavioural therapies, sleep hygiene (98%) and relaxation training (73%) were the most popular choices. Mindfulness (43%), CBT-I (29%), and sleep restriction were also cited. Drug therapies were the second most popular intervention overall for patients with insomnia among 99% of FPs surveyed. FPs indicated that they had experience prescribing

2017 CADTH - Optimal Use