Latest & greatest articles for influenza

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Top results for influenza

181. Pandemic Influenza Viruses - Hoping for the Road Not Taken.

Pandemic Influenza Viruses - Hoping for the Road Not Taken. Pandemic influenza viruses--hoping for the road not taken. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 23738514 Format MeSH and Other Data E-mail (...) Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2013 Jun 20;368(25):2345-8. doi: 10.1056/NEJMp1307009. Epub 2013 Jun 5. Pandemic influenza viruses--hoping for the road not taken. 1 , , . 1 Office of the Director, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. PMID: 23738514 PMCID: DOI: [Indexed for MEDLINE

NEJM2013 Full Text: Link to full Text with Trip Pro

182. Effect of double dose oseltamivir on clinical and virological outcomes in children and adults admitted to hospital with severe influenza: double blind randomised controlled trial.

Effect of double dose oseltamivir on clinical and virological outcomes in children and adults admitted to hospital with severe influenza: double blind randomised controlled trial. OBJECTIVE: To investigate the validity of recommendations in treatment guidelines to use higher than approved doses of oseltamivir in patients with severe influenza. DESIGN: Double blind randomised trial. SETTING: Thirteen hospitals in Indonesia, Singapore, Thailand, and Vietnam. PARTICIPANTS: Patients aged ≥ 1 year (...) admitted to hospital with confirmed severe influenza. INTERVENTIONS: Oral oseltamivir at double dose (150 mg twice a day/paediatric equivalent) versus standard dose (75 mg twice a day/paediatric equivalent). MAIN OUTCOME MEASURE: Viral status according to reverse transcriptase polymerase chain reaction (RT-PCR) for influenza RNA in nasal and throat swabs on day five. RESULTS: Of 326 patients (including 246 (75.5%) children aged <15), 165 and 161 were randomised to double or standard dose oseltamivir

BMJ2013 Full Text: Link to full Text with Trip Pro

183. Serologic Study for Influenza A (H7N9) among High-Risk Groups in China.

Serologic Study for Influenza A (H7N9) among High-Risk Groups in China. Serologic study for influenza A (H7N9) among high-risk groups in China. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 23718151 Format (...) MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2013 Jun 13;368(24):2339-40. doi: 10.1056/NEJMc1305865. Epub 2013 May 29. Serologic study for influenza A (H7N9) among high-risk groups in China. , , . PMID: 23718151 DOI: [Indexed for MEDLINE] Free full text Publication types MeSH terms Substance Full Text Sources Medical PubMed Commons 0

NEJM2013

184. Live-Animal Markets and Influenza A (H7N9) Virus Infection.

Live-Animal Markets and Influenza A (H7N9) Virus Infection. Live-animal markets and influenza A (H7N9) virus infection. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 23697471 Format MeSH and Other Data E-mail (...) Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2013 Jun 13;368(24):2337-9. doi: 10.1056/NEJMc1306100. Epub 2013 May 22. Live-animal markets and influenza A (H7N9) virus infection. , , , , , . PMID: 23697471 DOI: [Indexed for MEDLINE] Free full text Publication types MeSH terms Full Text Sources Medical PubMed Commons 0 comments How to cite this comment: Supplemental

NEJM2013

185. Clinical Findings in 111 Cases of Influenza A (H7N9) Virus Infection.

Clinical Findings in 111 Cases of Influenza A (H7N9) Virus Infection. BACKGROUND: During the spring of 2013, a novel avian-origin influenza A (H7N9) virus emerged and spread among humans in China. Data were lacking on the clinical characteristics of the infections caused by this virus. METHODS: Using medical charts, we collected data on 111 patients with laboratory-confirmed avian-origin influenza A (H7N9) infection through May 10, 2013. RESULTS: Of the 111 patients we studied, 76.6% were

NEJM2013

186. Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses.

Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses. BACKGROUND: On March 30, 2013, a novel avian influenza A H7N9 virus that infects human beings was identified. This virus had been detected in six provinces and municipal cities in China as of April 18, 2013. We correlated genomic sequences from avian influenza viruses with ecological information and did phylogenetic and coalescent analyses to extrapolate (...) the potential origins of the virus and possible routes of reassortment events. METHODS: We downloaded H7N9 virus genome sequences from the Global Initiative on Sharing Avian Influenza Data (GISAID) database and public sequences used from the Influenza Virus Resource. We constructed phylogenetic trees and did 1000 bootstrap replicates for each tree. Two rounds of phylogenetic analyses were done. We used at least 100 closely related sequences for each gene to infer the overall topology, removed suspicious

Lancet2013

187. Preliminary Report: Epidemiology of the Avian Influenza A (H7N9) Outbreak in China.

Preliminary Report: Epidemiology of the Avian Influenza A (H7N9) Outbreak in China. BACKGROUND: The first identified cases of avian influenza A(H7N9) virus infection in humans occurred in China during February and March 2013. We analyzed data obtained from field investigations to describe the epidemiologic characteristics of H7N9 cases in China identified as of December 1, 2013. METHODS: Field investigations were conducted for each confirmed case of H7N9 virus infection. A patient

NEJM2013

188. Global Concerns Regarding Novel Influenza A (H7N9) Virus Infections.

Global Concerns Regarding Novel Influenza A (H7N9) Virus Infections. Global concerns regarding novel influenza A (H7N9) virus infections. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 23577629 Format MeSH (...) and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2013 May 16;368(20):1862-4. doi: 10.1056/NEJMp1304661. Epub 2013 Apr 11. Global concerns regarding novel influenza A (H7N9) virus infections. 1 , . 1 Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, USA. Comment on [N

NEJM2013

189. Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus.

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus. BACKGROUND: Infection of poultry with influenza A subtype H7 viruses occurs worldwide, but the introduction of this subtype to humans in Asia has not been observed previously. In March 2013, three urban residents of Shanghai or Anhui, China, presented with rapidly progressing lower respiratory tract infections and were found to be infected with a novel reassortant avian-origin influenza A (H7N9) virus. METHODS: We obtained (...) and analyzed clinical, epidemiologic, and virologic data from these patients. Respiratory specimens were tested for influenza and other respiratory viruses by means of real-time reverse-transcriptase-polymerase-chain-reaction assays, viral culturing, and sequence analyses. RESULTS: A novel reassortant avian-origin influenza A (H7N9) virus was isolated from respiratory specimens obtained from all three patients and was identified as H7N9. Sequencing analyses revealed that all the genes from these three

NEJM2013

190. Chinese medicinal herbs for influenza.

Chinese medicinal herbs for influenza. BACKGROUND: Influenza is a communicable acute respiratory infection which, during epidemics, can cause high morbidity and mortality rates. Traditional Chinese medicinal herbs, often administered following a particular Chinese medical theory, may be a potential treatment of choice. OBJECTIVES: To assess the effect of Chinese medicinal herbs used to prevent and treat influenza and to estimate the frequency of adverse effects. SEARCH METHODS: We searched (...) CENTRAL (2012, Issue 11), MEDLINE (January 1966 to November week 2, 2012), EMBASE (January 1988 to November 2012) and CNKI (January 1988 to 29 March 2012). We also searched reference lists of articles and the WHO ICTRP search portal (November 2012). SELECTION CRITERIA: Randomised controlled trials (RCTs) comparing traditional Chinese medicinal herbs with placebo, no treatment or conventional medicine normally used in preventing and treating uncomplicated influenza. DATA COLLECTION AND ANALYSIS: Two

Cochrane2013

191. The use of antiviral drugs for influenza: Guidance for practitioners, 2012/2013; Paediatric summary

The use of antiviral drugs for influenza: Guidance for practitioners, 2012/2013; Paediatric summary The use of antiviral drugs for influenza: Guidance for practitioners, 2012/2013; Paediatric summary | Position statements and practice points | The use of antiviral drugs for influenza: Guidance for practitioners, 2012/2013; Paediatric summary | Canadian Paediatric Society Protecting and promoting the health and well-being of children and youth CPS Member Login | Who We Are What We Do Get (...) Involved Education/CPD Publications Careers > Share PRACTICE POINT The use of antiviral drugs for influenza: Guidance for practitioners, 2012/2013; Paediatric summary Posted: Mar 1 2013 Reaffirmed: Feb 1 2016 The Canadian Paediatric Society gives permission to print single copies of this document from our website. For permission to reprint or reproduce multiple copies, please see our . Principal author(s) Upton D Allen; Canadian Paediatric Society , Paediatr Child Health 2013;18(3):155-8 Abstract

Canadian Paediatric Society2013

192. Amantadine effect on peripheral airways abnormalities in influenza. A study in 15 students with natural influenza A infection.

Amantadine effect on peripheral airways abnormalities in influenza. A study in 15 students with natural influenza A infection. Amantadine effect on peripheral a... preview & related info | Mendeley E-mail address Password ( ) Remember me …or sign in with Search Main Navigation › Short URL Annals of Internal Medicine ( 1976 ) Volume: 85 , Issue: 2 , Pages: 177-182 PubMed: Available from or Find this paper at: Abstract Amantadine HCl administration has resulted in accelerated resolution (...) of influenza A illness. Prolonged abnormalities in pulmonary function have been described in uncomplicated influenza A. To study the effect of amantadine on these changes, we evaluated young adults with documented natural influenza A with clear chest examinations and X rays. Subjects received placebo or amantadine in random, double-blind fashion. Physiologic studies included maximal expiratory flow volume curves with air and helium-oxygen mixtures. Air flow rates were unchanged in all subjects throughout

Annals of Internal Medicine2013

193. ACP Journal Club. Review: Neuraminidase inhibitors relieve influenza symptoms and reduce laboratory-confirmed influenza in healthy adults.

ACP Journal Club. Review: Neuraminidase inhibitors relieve influenza symptoms and reduce laboratory-confirmed influenza in healthy adults. ACP Journal Club. Review: Neurami... preview & related info | Mendeley E-mail address Password ( ) Remember me …or sign in with Search Main Navigation › Short URL Annals of Internal Medicine ( 2010 ) Volume: 152 , Issue: 4 , Pages: JC-211 PubMed: Available from or Find this paper at: Abstract Questions: Are neuraminidase inhibitors effective for preventing (...) or treating influenza in healthy adults? What are the adverse effects? Review scope: Included studies compared neuraminidase inhibitors (oseltamivir or zanamivir) with placebo, antiviral controls, or no treatment in otherwise-healthy persons who were exposed to naturally occurring influenza. Studies had to include 75% of persons 14 to 60 years of age. Outcomes were influenza, influenza-like illness, influenza symptoms and complications (pneumonia, bronchitis, sinusitis, and otitis media requiring

Annals of Internal Medicine2013

194. Protective efficacy of combined live intranasal and inactivated influenza A virus vaccines in the elderly.

Protective efficacy of combined live intranasal and inactivated influenza A virus vaccines in the elderly. Protective efficacy of combined l... preview & related info | Mendeley E-mail address Password ( ) Remember me …or sign in with Search Main Navigation › Short URL Annals of Internal Medicine ( 1992 ) Volume: 117 , Issue: 8 , Publisher: Am Coll Physicians , Pages: 625-633 PubMed: Available from or Find this paper at: Abstract OBJECTIVE: To evaluate the efficacy of adding intranasal live (...) attenuated cold-adapted influenza A vaccine to inactivated influenza vaccine to prevent influenza A in elderly residents of long-term-care institutions. DESIGN: Randomized, double-blind, placebo-controlled study conducted over 3 years. SETTING: Three large nursing homes. PARTICIPANTS: A total of 523 residents of nursing homes (mean age, 84.2 years). INTERVENTIONS: All participants received trivalent inactivated influenza vaccine parenterally and were randomly assigned to receive either live attenuated

Annals of Internal Medicine2013

195. ACP Journal Club. Review: Extended-duration chemoprophylaxis with neuraminidase inhibitors prevents symptomatic influenza.

ACP Journal Club. Review: Extended-duration chemoprophylaxis with neuraminidase inhibitors prevents symptomatic influenza. ACP Journal Club. Review: Extende... preview & related info | Mendeley E-mail address Password ( ) Remember me …or sign in with Search Main Navigation › Short URL Annals of Internal Medicine ( 2010 ) Volume: 152 , Issue: 6 , Pages: JC3-C3 PubMed: Available from or Find this paper at: Abstract Question Is extended-duration chemoprophylaxis with neuraminidase inhibitors (NAIs (...) ) effective in preventing influenza? Review scope Included studies compared an NAI with placebo or another NAI, given for 4 weeks, for prevention of naturally occurring influenza A virus infection. Outcomes were laboratory-confirmed symptomatic or asymptomatic influenza virus infection and adverse events. Review methods MEDLINE, EMBASE/Excerpta Medica, BIOSIS, Cochrane Library, National Health Service Economic Evaluation, Health Technology Assessment, ACP Journal Club, Database of Abstracts of Reviews

Annals of Internal Medicine2013

196. Risk of narcolepsy in children and young people receiving AS03 adjuvanted pandemic A/H1N1 2009 influenza vaccine: retrospective analysis.

Risk of narcolepsy in children and young people receiving AS03 adjuvanted pandemic A/H1N1 2009 influenza vaccine: retrospective analysis. OBJECTIVE: To evaluate the risk of narcolepsy in children and adolescents in England targeted for vaccination with ASO3 adjuvanted pandemic A/H1N1 2009 vaccine (Pandemrix) from October 2009. DESIGN: Retrospective analysis. Clinical information and results of sleep tests were extracted from hospital notes between August 2011 and February 2012 and reviewed

BMJ2013

197. Influenza A/H1N1 MF59 adjuvanted vaccine in pregnant women and adverse perinatal outcomes: multicentre study.

Influenza A/H1N1 MF59 adjuvanted vaccine in pregnant women and adverse perinatal outcomes: multicentre study. OBJECTIVE: To assess the risk of adverse perinatal events of vaccination of pregnant women with an MF59 adjuvanted vaccine. DESIGN: Cross sectional multicentre study. SETTING: 49 public hospitals in major cities in Argentina, from September 2010 to May 2011. PARTICIPANTS: 30,448 mothers (7293 vaccinated) and their 30,769 newborns. MAIN OUTCOME MEASURE: Primary composite outcome of low (...) . These findings were consistent in further subgroup analysis. No significant differences in maternal outcomes were found. CONCLUSION: This large study using primary data collection found that MF59 adjuvanted A/H1N1 influenza vaccine did not result in an increased risk of adverse perinatal events and suggested a lower risk among vaccinated women. These findings should contribute to inform stakeholders and decision makers on the prescription of vaccination against influenza A/H1N1 in pregnant women.

BMJ2013 Full Text: Link to full Text with Trip Pro

198. Cost effectiveness of vaccination against pandemic influenza in European countries: mathematical modelling analysis

Cost effectiveness of vaccination against pandemic influenza in European countries: mathematical modelling analysis Cost effectiveness of vaccination against pandemic influenza in European countries: mathematical modelling analysis Cost effectiveness of vaccination against pandemic influenza in European countries: mathematical modelling analysis Lugner AK, van Boven M, de Vries R, Postma MJ, Wallinga J Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study examined the cost-effectiveness of having one strategy, for three countries, for vaccination against influenza during a pandemic. The authors concluded that the most cost-effective strategy depended on vaccine availability and the country. In most scenarios, vaccinating young

NHS Economic Evaluation Database.2013

199. Health and economic impact of the seasonal influenza vaccination programme in England

Health and economic impact of the seasonal influenza vaccination programme in England Health and economic impact of the seasonal influenza vaccination programme in England Health and economic impact of the seasonal influenza vaccination programme in England Baguelin M, Jit M, Miller E, Edmunds WJ Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions (...) followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The objective was to assess the cost-effectiveness of the existing seasonal influenza vaccination programme, in England. The authors concluded that the seasonal influenza vaccination programme appeared to reduce the disease burden and be good value for money. The results were not fully reported, but the methods were generally good, and the results are likely to be valid. Given the scope

NHS Economic Evaluation Database.2013

200. Risk of fetal death after pandemic influenza virus infection or vaccination.

Risk of fetal death after pandemic influenza virus infection or vaccination. BACKGROUND: During the 2009 influenza A (H1N1) pandemic, pregnant women were at risk for severe influenza illness. This concern was complicated by questions about vaccine safety in pregnant women that were raised by anecdotal reports of fetal deaths after vaccination. METHODS: We explored the safety of influenza vaccination of pregnant women by linking Norwegian national registries and medical consultation data (...) to determine influenza diagnosis, vaccination status, birth outcomes, and background information for pregnant women before, during, and after the pandemic. We used Cox regression models to estimate hazard ratios for fetal death, with the gestational day as the time metric and vaccination and pandemic exposure as time-dependent exposure variables. RESULTS: There were 117,347 eligible pregnancies in Norway from 2009 through 2010. Fetal mortality was 4.9 deaths per 1000 births. During the pandemic, 54

NEJM2013 Full Text: Link to full Text with Trip Pro