Latest & greatest articles for infection

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This page lists the very latest high quality evidence on infection and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Top results for infection

121. HIV Viral Suppression Trends Over Time Among HIV-Infected Patients Receiving Care in the United States, 1997 to 2015: A Cohort Study.

HIV Viral Suppression Trends Over Time Among HIV-Infected Patients Receiving Care in the United States, 1997 to 2015: A Cohort Study. Background: Because HIV viral suppression is essential for optimal outcomes and prevention efforts, understanding trends and predictors is imperative to inform public health policy. Objective: To evaluate viral suppression trends in people living with HIV (PLWH), including the relationship of associated factors, such as demographic characteristics and integrase

Annals of Internal Medicine2018

122. Clearance of Type-Specific, Low-Risk, and High-Risk Cervical Human Papillomavirus Infections in HIV-Negative and HIV-Positive Women

Clearance of Type-Specific, Low-Risk, and High-Risk Cervical Human Papillomavirus Infections in HIV-Negative and HIV-Positive Women 30125130 2018 12 07 2378-9506 4 2018 Jul Journal of global oncology J Glob Oncol Clearance of Type-Specific, Low-Risk, and High-Risk Cervical Human Papillomavirus Infections in HIV-Negative and HIV-Positive Women. 1-12 10.1200/JGO.17.00129 Purpose There is a dearth of data on clearance of cervical human papillomavirus (HPV) infection among women in West Africa. We (...) examined the clearance of low-risk (lr) and high-risk (hr) cervical HPV infections, and the factors associated with these measures in HIV-negative and HIV-positive women. Methods We studied 630 Nigerian women involved in a study of HPV infection using short polymerase chain reaction fragment-10 assay and line probe assay-25. Research nurses used a cervical brush to collect samples of exfoliated cervical cells from all the study participants. Cox proportional hazards models were used to estimate

Journal of global oncology2018 Full Text: Link to full Text with Trip Pro

123. Incidence of Plasmodium infections and determinant factors among febrile children in a district of Northwest Ethiopia; a cross-sectional study

Incidence of Plasmodium infections and determinant factors among febrile children in a district of Northwest Ethiopia; a cross-sectional study 30116548 2018 11 14 2055-0936 4 2018 Tropical diseases, travel medicine and vaccines Trop Dis Travel Med Vaccines Incidence of Plasmodium infections and determinant factors among febrile children in a district of Northwest Ethiopia; a cross-sectional study. 8 10.1186/s40794-018-0069-1 According to the Ethiopian national malaria indicator survey of 2015 (...) , the highest burden of Plasmodia infection resided among the school-age children. Even though several studies revealed various determinant factors of childhood malaria, consistent findings are not reported across the nation and elsewhere. This in turn creates obstacles in implementing exactprevention and control measures in the study area in particular and the country at large. The aim of this study is to determine the incidence of Plasmodium and determinant factors among febrile children in Northwest

Tropical diseases, travel medicine and vaccines2018 Full Text: Link to full Text with Trip Pro

124. Twelve-Month Outcomes After Transplant of Hepatitis C-Infected Kidneys Into Uninfected Recipients: A Single-Group Trial.

Twelve-Month Outcomes After Transplant of Hepatitis C-Infected Kidneys Into Uninfected Recipients: A Single-Group Trial. Background: Organs from hepatitis C virus (HCV)-infected deceased donors are often discarded. Preliminary data from 2 small trials, including THINKER-1 (Transplanting Hepatitis C kidneys Into Negative KidnEy Recipients), suggested that HCV-infected kidneys could be safely transplanted into HCV-negative patients. However, intermediate-term data on quality of life and renal (...) function are needed to counsel patients about risk. Objective: To describe 12-month HCV treatment outcomes, estimated glomerular filtration rate (eGFR), and quality of life for the 10 kidney recipients in THINKER-1 and 6-month data on 10 additional recipients. Design: Open-label, nonrandomized trial. (ClinicalTrials.gov: NCT02743897 ). Setting: Single center. Participants: 20 HCV-negative transplant candidates. Intervention: Participants underwent transplant with kidneys infected with genotype 1 HCV

Annals of Internal Medicine2018

125. Urinary tract infection

Urinary tract infection Top results for urinary tract infection - Trip Database or use your Google+ account Liberating the literature My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top (...) search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for urinary tract infection The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection

Trip Latest and Greatest2018

126. Does BCG Vaccination Protect Against Non-Tuberculous Mycobacterial Infection? A Systematic Review and Meta-Analysis

Does BCG Vaccination Protect Against Non-Tuberculous Mycobacterial Infection? A Systematic Review and Meta-Analysis 29635431 2018 07 30 1537-6613 218 5 2018 Jul 24 The Journal of infectious diseases J. Infect. Dis. Does BCG Vaccination Protect Against Nontuberculous Mycobacterial Infection? A Systematic Review and Meta-Analysis. 679-687 10.1093/infdis/jiy207 The incidence of nontuberculous mycobacterial (NTM) infections is increasing worldwide, particularly NTM lymphadenitis and skin infections (...) ]). No studies have compared different BCG vaccine strains or the effect of revaccination in this setting. The protective effect of BCG vaccination against NTM should be taken into consideration when deciding on recommendations for discontinuation of universal BCG vaccination programs and in assessing new vaccines designed to replace BCG. Zimmermann Petra P Department of Paediatrics, The University of Melbourne, Parkville, Australia. Infectious Diseases Unit, Royal Children's Hospital Melbourne, Parkville

EvidenceUpdates2018

127. Infection

Infection Top results for infection - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search (...) button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for infection The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory

Trip Latest and Greatest2018

128. Pegfilgrastim (LAPELGA) - is indicated to decrease the incidence of infection, as manifested by febrile neutropenia, in patients with non-myeloid malignancies receiving myelosuppressive antineoplastic drugs

Pegfilgrastim (LAPELGA) - is indicated to decrease the incidence of infection, as manifested by febrile neutropenia, in patients with non-myeloid malignancies receiving myelosuppressive antineoplastic drugs Search Page - Drug and Health Product Register Language selection Search and menus Search Search website Search Topics menu You are here: Summary Basis of Decision - - Health Canada Summary Basis of Decision (SBD) for Contact: Summary basis of decision (SBD) documents provide information

Health Canada - Drug and Health Product Register2018

129. Diagnosis and management of acute osteoarticular infections in children

Diagnosis and management of acute osteoarticular infections in children Acute hematogenous osteomyelitis and septic arthritis are not uncommon infections in children and should be considered as part of the differential diagnosis of limb pain and pseudoparalysis. Most bone infections in children arise secondary to hematogenous seeding of bacteria into bone. The most common pathogens are Staphylococcus aureus and Kingella kingae . Children with septic arthritis should be evaluated promptly (...) osteomyelitis; C-reactive protein test; Methicillin-resistant Staphylococcus aureus ; Methicillin-susceptible Staphylococcus aureus ; Septic arthritis

Canadian Paediatric Society2018

130. The value of quantitative histology in the diagnosis of fracture-related infection

The value of quantitative histology in the diagnosis of fracture-related infection 29954215 2018 07 10 2018 07 10 2049-4408 100-B 7 2018 07 The bone & joint journal Bone Joint J The value of quantitative histology in the diagnosis of fracture-related infection. 966-972 10.1302/0301-620X.100B7.BJJ-2018-0052.R1 This study aimed to investigate the role of quantitative histological analysis in the diagnosis of fracture-related infection (FRI). The clinical features, microbiology culture results (...) , and histological analysis in 156 surgically treated nonunions were used to stratify the likelihood of associated infection. There were 64 confirmed infected nonunions (one or more confirmatory criteria: pus, sinus, and bacterial growth in two or more samples), 66 aseptic nonunions (no confirmatory criteria), and 26 possibly infected nonunions (pathogen identified from a single specimen and no confirmatory criteria). The histological inflammatory response was assessed by average neutrophil polymorph (NPs

EvidenceUpdates2018

131. Risk of Infective Endocarditis After Invasive Dental Treatments: A Case-Only Study

Risk of Infective Endocarditis After Invasive Dental Treatments: A Case-Only Study 29674326 2018 04 20 1524-4539 2018 Apr 19 Circulation Circulation Risk of Infective Endocarditis After Invasive Dental Treatments: A Case-Only Study. CIRCULATIONAHA.117.033131 10.1161/CIRCULATIONAHA.117.033131 Background -Invasive dental treatments (IDTs) can yield temporary bacteremia and has therefore been considered a potential risk factor of infective endocarditis (IE). It is hypothesized that, through (...) University, Taipei, Taiwan. Tu Yu-Kang YK Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan & Department of Dentistry, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan yukangtu@ntu.edu.tw. eng Journal Article 2018 04 19 United States Circulation 0147763 0009-7322 case-crossover design infective endocarditis invasive dental treatments self-controlled case series design 2018 04 09 2017 12 07 2018 03 12 2018 4

EvidenceUpdates2018

132. The Society for Vascular Surgery Wound, Ischemia, and foot Infection (WIfI) classification system predicts wound healing better than direct angiosome perfusion in diabetic foot wounds

The Society for Vascular Surgery Wound, Ischemia, and foot Infection (WIfI) classification system predicts wound healing better than direct angiosome perfusion in diabetic foot wounds 29803684 2018 05 27 1097-6809 2018 May 23 Journal of vascular surgery J. Vasc. Surg. The Society for Vascular Surgery Wound, Ischemia, and foot Infection (WIfI) classification system predicts wound healing better than direct angiosome perfusion in diabetic foot wounds. S0741-5214(18)30418-X 10.1016/j.jvs (...) .2018.01.060 Previous studies show conflicting results in wound healing outcomes based on angiosome direct perfusion (DP), but few have adjusted for wound characteristics in their analyses. We have previously shown that the Society for Vascular Surgery Wound, Ischemia, and foot Infection (WIfI) classification correlates with wound healing in diabetic foot ulcers (DFUs) treated by a multidisciplinary team. The aim of this study was to compare WIfI classification vs DP and pedal arch patency as predictors

EvidenceUpdates2018

133. Bictegravir / emtricitabine / tenofovir alafenamide / fumarate (Biktarvy) - HIV Infections

Bictegravir / emtricitabine / tenofovir alafenamide / fumarate (Biktarvy) - HIV Infections 30 Churchill Place ? Canary Wharf ? London E14 5EU ? United Kingdom An agency of the European Union Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5555 Send a question via our website www.ema.europa.eu/contact © European Medicines Agency, 2018. Reproduction is authorised provided the source is acknowledged. 26 April 2018 EMA/293559/2018 Committee for Medicinal Products for Human Use (CHMP (...) substance: Bictegravir / Emtricitabine / Tenofovir Alafenamide International Non-proprietary Name/Common Name: Bictegravir / Emtricitabine / Tenofovir Alafenamide Pharmaco-therapeutic group (ATC Code): Direct acting antivirals, antivirals for treatment of HIV infections, combinations (J05AR) Therapeutic indication(s): Biktarvy is indicated for the treatment of adults infected with human immunodeficiency virus 1 (HIV 1) without present or past evidence of viral resistance to the integrase inhibitor class

European Medicines Agency - EPARs2018

134. Dalbavancin (Xydalba) - treatment of acute bacterial skin and skin structure infections (ABSSSI) in adults

Dalbavancin (Xydalba) - treatment of acute bacterial skin and skin structure infections (ABSSSI) in adults Final Appraisal Recommendation Advice No: 1118 – July 2018 Dalbavancin (Xydalba ® ) 500 mg powder for concentrate for solution for infusion Submission by Cardiome UK Ltd In reaching the above recommendation AWMSG has taken account of the appraisal documentation prepared by the AWMSG Secretariat (reference number 2001), which includes the AWMSG Secretariat Assessment Report (ASAR (...) in the following circumstances within its licensed indication for the treatment of acute bacterial skin and skin structure infections (ABSSSI) in adults: • as a second-line treatment of ABSSSI; or • when methicillin-resistant Staphylococcus aureus (MRSA) infection is suspected; or • on the advice of local microbiologists or infectious disease specialists; and • the patient is at first hospitalised due to ABSSSI and needs intravenous antibiotics but is allowed early discharge as they don’t need further

All Wales Medicines Strategy Group2018

135. A survey on infection control in emergency departments in Japan

A survey on infection control in emergency departments in Japan 30338085 2018 11 14 2052-8817 5 4 2018 Oct Acute medicine & surgery Acute Med Surg A survey on infection control in emergency departments in Japan. 374-379 10.1002/ams2.360 Infection control in the emergency department is important for hospital risk management; however, few clinical guidelines have been established. This study aimed to determine whether hospitals in Japan have infection control manuals, and investigate the contents (...) of manuals, consulting systems, and isolation facilities for emergency departments. A total of 517 hospitals certified as educational institutions for board-certified acute care physicians in Japan were requested between March and May 2015 to provide a written evaluation of the infection control in the emergency department. A total of 51 of 303 (16.8%) hospitals had no manuals regarding infection control in the emergency department. Among 250 hospitals having emergency department manuals, 115 (46.0%) did

Acute medicine & surgery2018 Full Text: Link to full Text with Trip Pro

136. Treatment for chronic methicillin-sensitive Staphylococcus aureus pulmonary infection in people with cystic fibrosis.

Treatment for chronic methicillin-sensitive Staphylococcus aureus pulmonary infection in people with cystic fibrosis. BACKGROUND: Cystic fibrosis is an inherited life-threatening multisystem disorder with lung disease characterized by abnormally thick airway secretions and persistent bacterial infection. Chronic, progressive lung disease is the most important cause of morbidity and mortality in the condition and is therefore the main focus of clinical care and research. Staphylococcus aureus (...) is a major cause of chest infection in people with cystic fibrosis. Early onset, as well as chronic, lung infection with this organism in young children and adults results in worsening lung function, poorer nutrition and increases the airway inflammatory response, thus leading to a poor overall clinical outcome. There are currently no evidence-based guidelines for chronic suppressive therapy for Staphylococcus aureus infection in cystic fibrosis such as those used for Pseudomonas aeruginosa infection

Cochrane2018

137. Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2018 Recommendations of the International Antiviral Society-USA Panel.

Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2018 Recommendations of the International Antiviral Society-USA Panel. Importance: Antiretroviral therapy (ART) is the cornerstone of prevention and management of HIV infection. Objective: To evaluate new data and treatments and incorporate this information into updated recommendations for initiating therapy, monitoring individuals starting therapy, changing regimens, and preventing HIV infection for individuals (...) at risk. Evidence Review: New evidence collected since the International Antiviral Society-USA 2016 recommendations via monthly PubMed and EMBASE literature searches up to April 2018; data presented at peer-reviewed scientific conferences. A volunteer panel of experts in HIV research and patient care considered these data and updated previous recommendations. Findings: ART is recommended for virtually all HIV-infected individuals, as soon as possible after HIV diagnosis. Immediate initiation (eg

JAMA2018

138. Probiotics to Prevent Clostridium difficile Infection in Patients Receiving Antibiotics.

Probiotics to Prevent Clostridium difficile Infection in Patients Receiving Antibiotics. Clinical Question: In adults and children prescribed antibiotics, is co-administration of a probiotic associated with a lower risk of symptomatic Clostridium difficile infection without an increase in adverse events? Bottom Line: Moderate-quality evidence suggests that probiotics are associated with a lower risk of C difficile infection and very low-quality evidence suggests that probiotics are associated

JAMA2018

139. State-of-the-art diagnosis and surgical treatment of acute peri-prosthetic joint infection following primary total hip arthroplasty

State-of-the-art diagnosis and surgical treatment of acute peri-prosthetic joint infection following primary total hip arthroplasty 30233819 2018 11 14 2058-5241 3 7 2018 Jul EFORT open reviews EFORT Open Rev State-of-the-art diagnosis and surgical treatment of acute peri-prosthetic joint infection following primary total hip arthroplasty. 434-441 10.1302/2058-5241.3.170032 Acute peri-prosthetic joint infection (PJI) following total hip arthroplasty (THA) is a potentially devastating (...) and undesired complication, with a prevalence of 0.3% to 2.9%. Its suspicion begins with a meticulous physical examination and anamnesis. Diagnosis should be made on the basis of the Musculoskeletal Infection Society criteria. Serum and synovial biomarkers are very useful tools when major criteria are absent.Although sometimes not possible due to medical conditions, surgery is usually the first line of treatment. Although its outcome is highly correlated with the isolated microorganism, irrigation

EFORT open reviews2018 Full Text: Link to full Text with Trip Pro

140. Vaginal preparation with antiseptic solution before cesarean section for preventing postoperative infections.

Vaginal preparation with antiseptic solution before cesarean section for preventing postoperative infections. BACKGROUND: Cesarean delivery is one of the most common surgical procedures performed by obstetricians. Infectious morbidity after cesarean delivery can have a tremendous impact on the postpartum woman's return to normal function and her ability to care for her baby. Despite the widespread use of prophylactic antibiotics, postoperative infectious morbidity still complicates cesarean (...) deliveries. This is an update of a Cochrane review first published in 2010 and subsequently updated in 2012, and twice in 2014. OBJECTIVES: To determine if cleansing the vagina with an antiseptic solution before a cesarean delivery decreases the risk of maternal infectious morbidities, including endometritis and wound complications. We also assessed the side effects of vaginal cleansing solutions to determine adverse events associated with the intervention. SEARCH METHODS: We searched Cochrane Pregnancy

Cochrane2018