Latest & greatest articles for infection

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on infection or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on infection and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for infection

1. Masks for Prevention of Respiratory Virus Infections, Including SARS-CoV-2, in Health Care and Community Settings: A Living Rapid Review. (Abstract)

Masks for Prevention of Respiratory Virus Infections, Including SARS-CoV-2, in Health Care and Community Settings: A Living Rapid Review. Recommendations on masks for preventing coronavirus disease 2019 (COVID-19) vary.To examine the effectiveness of N95, surgical, and cloth masks in community and health care settings for preventing respiratory virus infections, and effects of reuse or extended use of N95 masks.Multiple electronic databases, including the World Health Organization COVID-19 (...) database and medRxiv preprint server (2003 through 14 April 2020; surveillance through 2 June 2020), and reference lists.Randomized trials of masks and risk for respiratory virus infection, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and observational studies of mask use and coronavirus infection risk were included. New evidence will be incorporated by using living review methods.One reviewer abstracted data and assessed methodological limitations; a second reviewer provided

2020 Annals of Internal Medicine

2. Use of Anticoagulation in Patients with COVID-19 Infection (Full text)

Use of Anticoagulation in Patients with COVID-19 Infection Use of Anticoagulation in Patients with COVID-19 Infection - CanadiEM Use of Anticoagulation in Patients with COVID-19 Infection In by Johnny Huang June 18, 2020 Introduction The novel coronavirus, known as COVID-19, was originally reported in a cluster of pneumonia cases in Wuhan (China) near the end of 2019 ​1​ . Over the next 6 months, COVID-19 has emerged as the world’s newest pandemic disease with over 7 million cases worldwide ​1 (...) ​ . The clinical presentation of COVID-19 is broad and classically involves fever, cough, dyspnea, malaise, and bilateral infiltrates on chest imaging. Less typical symptoms including diarrhea, myalgia, confusion, anosmia, and ageusia were also reported in the literature ​2​ . In terms of investigations, patients with COVID-19 infection may have lymphopenia, elevated lactate dehydrogenase level, and elevated inflammatory markers such as ferritin or C-reactive protein ​3​ . There has been increasing evidence

2020 CandiEM PubMed abstract

3. Systematic or Test-Guided Treatment for Tuberculosis in HIV-Infected Adults. (Abstract)

Systematic or Test-Guided Treatment for Tuberculosis in HIV-Infected Adults. In regions with high burdens of tuberculosis and human immunodeficiency virus (HIV), many HIV-infected adults begin antiretroviral therapy (ART) when they are already severely immunocompromised. Mortality after ART initiation is high in these patients, and tuberculosis and invasive bacterial diseases are common causes of death.We conducted a 48-week trial of empirical treatment for tuberculosis as compared (...) with treatment guided by testing in HIV-infected adults who had not previously received ART and had CD4+ T-cell counts below 100 cells per cubic millimeter. Patients recruited in Ivory Coast, Uganda, Cambodia, and Vietnam were randomly assigned in a 1:1 ratio to undergo screening (Xpert MTB/RIF test, urinary lipoarabinomannan test, and chest radiography) to determine whether treatment for tuberculosis should be started or to receive systematic empirical treatment with rifampin, isoniazid, ethambutol

2020 NEJM

4. Health System Costs of Treating Latent Tuberculosis Infection With Four Months of Rifampin Versus Nine Months of Isoniazid in Different Settings. (Abstract)

Health System Costs of Treating Latent Tuberculosis Infection With Four Months of Rifampin Versus Nine Months of Isoniazid in Different Settings. Four months of rifampin treatment for latent tuberculosis infection is safer, has superior treatment completion rates, and is as effective as 9 months of isoniazid. However, daily medication costs are higher for a 4-month rifampin regimen than a 9-month isoniazid regimen.To compare health care use and associated costs of 4 months of rifampin and 9

2020 Annals of Internal Medicine

5. Meningococcal disease and sexual transmission: urogenital and anorectal infections and invasive disease due to Neisseria meningitidis. (Abstract)

Meningococcal disease and sexual transmission: urogenital and anorectal infections and invasive disease due to Neisseria meningitidis. Neisseria meningitidis is an obligate human commensal bacterium that frequently colonises the upper respiratory tract. Person-to-person transmission occurs via direct contact or through dispersion of respiratory droplets from a carrier of the bacteria, and can lead to invasive meningococcal disease. Rare sporadic cases of meningococcal urogenital and anorectal (...) infections, including urethritis, proctitis, and cervicitis, have been reported, typically following orogenital contact with an oropharyngeal meningococcal carrier. The resulting infections were clinically indistinguishable from infections caused by Neisseria gonorrhoeae. Over the past two decades, there have also been multiple outbreaks across North America and Europe of invasive meningococcal disease among men who have sex with men (MSM). The responsible meningococci belong to a highly virulent

2020 Lancet

6. Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study. (Full text)

Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study. To describe a national cohort of pregnant women admitted to hospital with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the UK, identify factors associated with infection, and describe outcomes, including transmission of infection, for mothers and infants.Prospective national population based cohort study using the UK (...) Obstetric Surveillance System (UKOSS).All 194 obstetric units in the UK.427 pregnant women admitted to hospital with confirmed SARS-CoV-2 infection between 1 March 2020 and 14 April 2020.Incidence of maternal hospital admission and infant infection. Rates of maternal death, level 3 critical care unit admission, fetal loss, caesarean birth, preterm birth, stillbirth, early neonatal death, and neonatal unit admission.The estimated incidence of admission to hospital with confirmed SARS-CoV-2 infection

2020 BMJ PubMed abstract

7. Prevalence of Asymptomatic SARS-CoV-2 Infection: A Narrative Review. (Full text)

Prevalence of Asymptomatic SARS-CoV-2 Infection: A Narrative Review. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly throughout the world since the first cases of coronavirus disease 2019 (COVID-19) were observed in December 2019 in Wuhan, China. It has been suspected that infected persons who remain asymptomatic play a significant role in the ongoing pandemic, but their relative number and effect have been uncertain. The authors sought to review and synthesize (...) the available evidence on asymptomatic SARS-CoV-2 infection. Asymptomatic persons seem to account for approximately 40% to 45% of SARS-CoV-2 infections, and they can transmit the virus to others for an extended period, perhaps longer than 14 days. Asymptomatic infection may be associated with subclinical lung abnormalities, as detected by computed tomography. Because of the high risk for silent spread by asymptomatic persons, it is imperative that testing programs include those without symptoms

2020 Annals of Internal Medicine PubMed abstract

8. Breastfeeding Guidance Post Hospital Discharge for Mothers or Infants with Suspected or Confirmed SARS-Co V-2 Infection

Breastfeeding Guidance Post Hospital Discharge for Mothers or Infants with Suspected or Confirmed SARS-Co V-2 Infection Breastfeeding Guidance Post Hospital Discharge for Mothers or Infants with Suspected or Confirmed SARS-Co V-2 Infection Internet Explorer Alert It appears you are using Internet Explorer as your web browser. Please note, Internet Explorer is no longer up-to-date and can cause problems in how this website functions This site functions best using the latest versions of any (...) of the following browsers: Edge, Firefox, Chrome, Opera, or Safari . You can find the latest versions of these browsers at More Breastfeeding Guidance Post Hospital Discharge for Mothers or Infants with Suspected or Confirmed SARS-Co V-2 Infection / / Breastfeeding Guidance Post Hospital Discharge for Mothers or Infants with Suspected or Confirmed SARS-Co V-2 Infection This guidance was developed to support pediatricians providing direct care for breastfeeding families after discharge from the newborn hospital

2020 American Academy of Pediatrics

9. Transmission of Respiratory Infection via Showers, Annotated Bibliography

reservoirs of infectious diseases may delineate whether surface decontamination is an effective target of hygiene interventions in this population. CEP Annotated Bibliography: Transmission of viral diseases in showers 4 539. Haxall K., Cohen B., Miko B.A., Conway L., Kelly N., Stare D., et al. Personal and household hygiene, microbial contamination, and health status in undergraduate residence halls in New York City. Am J Infect Control. 2012;40(5):e93-5 http://dx.doi.org.proxy.library.upenn.edu/10.1016 (...) Transmission of Respiratory Infection via Showers, Annotated Bibliography TRANSMISSION OF RESPIRATORY INFECTIONS VIA SHOWERS An Annotated Bibliography from the Penn Medicine Center for Evidence-based Practice May 2020 Project director: S. Ryan Greysen, MD, MHS, MA (CEP) Lead analyst: Matthew D. Mitchell, PhD (CEP) Internal review: Patrick J. Brennan, M.D. (CMO) Keywords: COVID-19, respiratory infection, infection control, shower, dormitory Summary We found no articles specifically referring

2020 Centre for Evidence-Based Practice, Penn Medicine

10. COVID-19: Infectivity of patients who have recovered from disease

societies CEP Rapid Guidance Summary: Infectivity of recovered COVID-19 patients June 8, 2020 2 Public health agency and professional society guidelines on lifting isolation and other precautions (not specific to medical care settings) Source Recommendations PHE May 20 Infection prevention and control (IPC) measures should continue for COVID-19 patients until 14 days have elapsed since their first positive SARS-CoV-2 test. This is due to uncertainties about the duration of infectiousness for patients (...) COVID-19 patients June 8, 2020 3 Evidence reviews on viral shedding Reviewer Findings FLARE May 22 Antibody testing cannot speak to infectivity and contagiousness. Individuals with SARS-CoV-2 seropositivity may nevertheless shed contagious virus and, conversely, seronegativity does not rule out acute infection. ECDC April 8 Incubation period: The median incubation period is considered to be five to six days for COVID-19, with a range from one to 14 days. According to modelling data it remains

2020 Centre for Evidence-Based Practice, Penn Medicine

11. Efficacy and safety of convalescent plasma for severe COVID-19 based on evidence in other severe respiratory viral infections: a systematic review and meta-analysis (Full text)

Efficacy and safety of convalescent plasma for severe COVID-19 based on evidence in other severe respiratory viral infections: a systematic review and meta-analysis Efficacy and Safety of Convalescent Plasma for Severe COVID-19 Based on Evidence in Other Severe Respiratory Viral Infections: A Systematic Review and Meta-Analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other (...) for external citation management software Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation CMAJ Actions . 2020 May 22;cmaj.200642. doi: 10.1503/cmaj.200642. Online ahead of print. Efficacy and Safety of Convalescent Plasma for Severe COVID-19 Based on Evidence in Other Severe Respiratory Viral Infections: A Systematic Review and Meta-Analysis , , , , , , , , Affiliations Expand Affiliation 1

2020 EvidenceUpdates PubMed abstract

12. Evolocumab in HIV-Infected Patients With Dyslipidemia: Primary Results of the Randomized, Double-Blind BEIJERINCK Study (Full text)

Evolocumab in HIV-Infected Patients With Dyslipidemia: Primary Results of the Randomized, Double-Blind BEIJERINCK Study Evolocumab in HIV-Infected Patients With Dyslipidemia: Primary Results of the Randomized, Double-Blind BEIJERINCK Study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes of Health National (...) : Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation J Am Coll Cardiol Actions . 2020 May 26;75(20):2570-2584. doi: 10.1016/j.jacc.2020.03.025. Epub 2020 Mar 28. Evolocumab in HIV-Infected Patients With Dyslipidemia: Primary Results of the Randomized, Double-Blind BEIJERINCK Study , , , , , , , , Collaborators, Affiliations Expand Collaborators BEIJERINCK Investigators

2020 EvidenceUpdates PubMed abstract

13. Efficacy and safety of corticosteroids in COVID-19 based on evidence for COVID-19, other coronavirus infections, influenza, community-acquired pneumonia and acute respiratory distress syndrome: a systematic review and meta-analysis (Full text)

Efficacy and safety of corticosteroids in COVID-19 based on evidence for COVID-19, other coronavirus infections, influenza, community-acquired pneumonia and acute respiratory distress syndrome: a systematic review and meta-analysis Efficacy and Safety of Corticosteroids in COVID-19 Based on Evidence for COVID-19, Other Coronavirus Infections, Influenza, Community-Acquired Pneumonia and Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis - PubMed This site needs JavaScript (...) Coronavirus Infections, Influenza, Community-Acquired Pneumonia and Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis , , , , , , , , , , , , , , Affiliations Expand Affiliation 1 Department of Health Research Methods, Evidence and Impact (Ye, Tangamornsuksan, Rochwerg, Guyatt, Colunga-Lozano, Yao, Motaghi, Fang, Xiao), McMaster University, Hamilton, Ont.; Department of Pharmacy (Wang), Beijing Chaoyang Hospital, Capital Medical University, Beijing, China; Department of Clinical

2020 EvidenceUpdates PubMed abstract

14. Impact of corticosteroid therapy on outcomes of persons with SARS-CoV-2, SARS-CoV, or MERS-CoV infection: a systematic review and meta-analysis (Full text)

Impact of corticosteroid therapy on outcomes of persons with SARS-CoV-2, SARS-CoV, or MERS-CoV infection: a systematic review and meta-analysis Impact of Corticosteroid Therapy on Outcomes of Persons With SARS-CoV-2, SARS-CoV, or MERS-CoV Infection: A Systematic Review and Meta-Analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily (...) Create file Cancel Your RSS Feed Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Share Permalink Copy Page navigation Meta-Analysis Leukemia Actions . 2020 Jun;34(6):1503-1511. doi: 10.1038/s41375-020-0848-3. Epub 2020 May 5. Impact of Corticosteroid Therapy on Outcomes of Persons With SARS-CoV-2, SARS-CoV, or MERS-CoV Infection: A Systematic Review and Meta-Analysis , , , , , , Affiliations Expand Affiliations 1 Department of Hematologic Oncology, State Key

2020 EvidenceUpdates PubMed abstract

15. High consequence infectious diseases (HCID)

High consequence infectious diseases (HCID) High consequence infectious diseases (HCID) - GOV.UK GOV.UK uses cookies to make the site simpler. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance High consequence infectious diseases (HCID) Guidance and information about high consequence infectious diseases and their management in England. Published 22 October 2018 Last updated 13 May 2019 — From: Contents Definition of Monthly summaries of global . Infection (...) prevention and control in healthcare settings Specific infection prevention and control ( . Specialist advice for healthcare professionals The provides 24-hour, 7-days a week telephone access to expert clinical and microbiological advice. Hospital doctors across the UK can contact the before discussing transfer. Travel health advice for . Published 22 October 2018 Last updated 13 May 2019 13 May 2019 Amended the definitions for HCID. 17 April 2019 Added explanation for inclusion of avian influenza H5N6

2020 Public Health England

16. COVID-19: guidance for stepdown of infection control precautions within hospitals and discharging COVID-19 patients from hospital to home settings

COVID-19: guidance for stepdown of infection control precautions within hospitals and discharging COVID-19 patients from hospital to home settings COVID-19: guidance for stepdown of infection control precautions within hospitals and discharging COVID-19 patients from hospital to home settings - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve (...) accepted all cookies. You can at any time. Hide Search Stay at home Only go outside for food, health reasons or work (but only if you cannot work from home) If you go out, stay 2 metres (6ft) away from other people at all times Wash your hands as soon as you get home Do not meet others, even friends or family. You can spread the virus even if you don’t have symptoms. Guidance COVID-19: guidance for stepdown of infection control precautions within hospitals and discharging COVID-19 patients from

2020 Public Health England

17. Infection prevention and control for COVID-19: interim guidance for long term care homes

are on Droplet and Contact precautions. If the visitor is unable to adhere to appropriate precautions, the visitor must be excluded from visiting. Resident care and infection control measures Point-of-care risk assessment (PCRA) Prior to any resident interaction, all staff have a responsibility to assess the infectious risks posed to themselves, other staff, other residents and visitors from a resident, situation or procedure. The PCRA is a routine practice that should be applied before every clinical (...) encounter regardless of COVID-19 status and is based on the staff professional judgment (i.e. knowledge, skills, reasoning and education) made regarding the likelihood of exposing themselves and/or others to infectious agents (e.g., COVID- 19), for a specific interaction, a specific task, with a specific resident, and in a specific environment, under available conditions. The PCRA helps staff to select the appropriate actions and/or PPE to minimize the risk of exposure to known and unknown infections

2020 CPG Infobase

18. Hepatitis C Virus Infection in Adolescents and Adults: Screening

by the USPSTF are independent of the U.S. government. They should not be construed as an official position of the Agency for Healthcare Research and Quality or the U.S. Department of Health and Human Services. Collapse All Hepatitis C virus (HCV) is the most common chronic blood-borne pathogen in the US and a leading cause of complications from chronic liver disease. Hepatitis C virus infection is associated with more deaths than the top 60 other reportable infectious diseases combined, including HIV (...) Med . Published online December 3, 2019. 14. Tran TT, Ahn J, Reau NS. ACG clinical guideline: liver disease and pregnancy. Am J Gastroenterol . 2016;111(2):176-194. 15. American Association for the Study of Liver Diseases, Infectious Diseases Society of America. HCV testing and linkage to care. Accessed January 23, 2020. . 16. Centers for Disease Control and Prevention. Testing recommendations for hepatitis C virus infection. Accessed January 23, 2020. . 17. Owens DK, Davidson KW, Krist AH, et al

2020 U.S. Preventive Services Task Force

19. Guidance on infection prevention and control of COVID-19 in migrant and refugee reception and detention centres in the EU/EEA and the UK

Guidance on infection prevention and control of COVID-19 in migrant and refugee reception and detention centres in the EU/EEA and the UK Guidance on infection prevention and control of COVID-19 in migrant and refugee reception and detention centres in the EU/EEA and the UK Global Navigation Other sites: European Centre for Disease Prevention and Control An agency of the European Union Main Navigation Secondary Navigation Search Search Search Search Guidance on infection prevention and control (...) of COVID-19 in migrant and refugee reception and detention centres in the EU/EEA and the UK Guidance on infection prevention and control of COVID-19 in migrant and refugee reception and detention centres in the EU/EEA and the UK Technical report 15 Jun 2020 Cite: European Centre for Disease Prevention and Control. Guidance on infection prevention and control of coronavirus disease (COVID-19) in migrant and refugee reception and detention centres in the EU/EEA and the United Kingdom – June 2020. ECDC

2020 European Centre for Disease Prevention and Control - Technical Guidance

20. Rapid risk assessment: Paediatric inflammatory multisystem syndrome and SARS -CoV-2 infection in children

Rapid risk assessment: Paediatric inflammatory multisystem syndrome and SARS -CoV-2 infection in children Rapid risk assessment: Paediatric inflammatory multisystem syndrome and SARS -CoV-2 infection in children Global Navigation Other sites: European Centre for Disease Prevention and Control An agency of the European Union Main Navigation Secondary Navigation Search Search Search Search Rapid risk assessment: Paediatric inflammatory multisystem syndrome and SARS -CoV-2 infection in children (...) Rapid risk assessment: Paediatric inflammatory multisystem syndrome and SARS -CoV-2 infection in children Risk assessment 15 May 2020 Cite: European Centre for Disease Prevention and Control. Paediatric inflammatory multisystem syndrome and SARS-CoV-2 infection in children – 15 May 2020. ECDC: Stockholm; 2020. Several countries affected by the coronavirus disease (COVID-19) pandemic recently reported cases of children that were hospitalised in intensive care due to a rare paediatric inflammatory

2020 European Centre for Disease Prevention and Control - Technical Guidance