Latest & greatest articles for infants

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Top results for infants

141. A Randomized Double Blind Trial of Needle-free Injected Lidocaine Versus Topical Anesthesia for Infant Lumbar Puncture

A Randomized Double Blind Trial of Needle-free Injected Lidocaine Versus Topical Anesthesia for Infant Lumbar Puncture 29160002 2017 12 26 1553-2712 2017 Nov 20 Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Acad Emerg Med A Randomized Double Blind Trial of Needle-free Injected Lidocaine Versus Topical Anesthesia for Infant Lumbar Puncture. 10.1111/acem.13351 Lumbar punctures (LPs) are commonly performed in febrile infants to evaluate (...) for meningitis, and local anesthesia increases the likelihood of LP success. Traditional methods of local anesthesia require injection that may be painful or topical application that is not effective immediately. Recent advances in needle-free jet injection may offer a rapid alternative to these modalities. We compared a needle-free jet-injection system (J-Tip) with 1% buffered lidocaine to topical anesthetic (TA) cream for local anesthesia in infant LPs. This was a single-center randomized double-blind

EvidenceUpdates2018

142. A Randomized Trial of Conditioned or Unconditioned Gases for Stabilizing Preterm Infants at Birth

A Randomized Trial of Conditioned or Unconditioned Gases for Stabilizing Preterm Infants at Birth 29106924 2017 11 06 1097-6833 2017 Oct 26 The Journal of pediatrics J. Pediatr. A Randomized Trial of Conditioned or Unconditioned Gases for Stabilizing Preterm Infants at Birth. S0022-3476(17)31167-8 10.1016/j.jpeds.2017.09.006 To determine whether the use of heated-humidified gases for respiratory support during the stabilization of infants <30 weeks of gestational age (GA) in the delivery room (...) reduces rates of hypothermia on admission to the neonatal intensive care unit (NICU). A multicenter, unblinded, randomized trial was conducted in Melbourne, Australia, between February 2013 and June 2015. Infants <30 weeks of GA were randomly assigned to receive either heated-humidified gases or unconditioned gases during stabilization in the delivery room and during transport to NICU. Infants born to mothers with pyrexia >38°C were excluded. Primary outcome was rate of hypothermia on NICU admission

EvidenceUpdates2018

143. Effectiveness of Text Messaging Interventions Designed to Influence Parents? Infant Feeding Practices: A Focused Practice Question

Effectiveness of Text Messaging Interventions Designed to Influence Parents? Infant Feeding Practices: A Focused Practice Question Effectiveness of Text Messaging Interventions Designed to Influence Parents’ Infant Feeding Practices A Focused Practice Question Sarah Lamontagne, Public Health Nutritionist Nicole Labrie, Supervisor February 2017 i Table of Contents Key Messages 1 Issue & Context 2 Literature Review Question 3 Literature Search 4 Relevance Assessment 4 Results of the Search 5 (...) information that results in improved health outcomes and/or changed health behaviors. 2. There is limited research on text messaging specifically to the target audience of parents with the goal of influencing their infant feeding practices. 3. Breastfeeding initiation and breastfeeding exclusivity maintenance can be improved with the use of text messaging interventions for parents. 4. The limited research available supports Peel Public Health in pursuing the development and evaluation of an intervention

Peel Health Library2018

144. Disorders of infant feeding

Disorders of infant feeding Disorders of infant feeding - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Disorders of infant feeding Last reviewed: August 2018 Last updated: March 2018 Summary Common in children under 1 year of age. Causative conditions may persist, leading to ongoing feeding difficulties during childhood. Results in the inadequate intake or intolerance of fluids or nutrients necessary to meet (...) are guided by physical findings and severity of symptoms. Feeding disorders are usually subacute to chronic in nature. A sudden change in feeding habit may be associated with other conditions, notably infections, which need to be excluded. Definition Conditions that lead to inadequate intake or intolerance of fluids and nutrients in infants under 1 year of age. Milnes SM, Piazza CC, Carroll-Hernandez TA. Assessment and treatment of pediatric feeding disorders. Encyclopedia on early childhood development

BMJ Best Practice2018

145. Abusive head trauma in infants

Abusive head trauma in infants Abusive head trauma in infants - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Abusive head trauma in infants Last reviewed: August 2018 Last updated: April 2018 Summary Abusive head trauma refers to the constellation of cranial, spinal cord, and brain injuries which result from inflicted injury in infants and young children. Diagnosis rests on the finding of unexplained injury (...) to the skull, brain, and/or spinal cord in an infant who has no other medical explanation for their clinical presentation. Frequently, there are other associated findings such as widespread retinal haemorrhaging, unexplained bruising, fractures and/or abdominal trauma. These additional findings are not necessary to make the diagnosis of abusive head trauma. The clinical presentation and degree of injury occur on a spectrum from mild to severe. Around 16% to 38% of victims die from their injuries. Most

BMJ Best Practice2018

146. Effectiveness of supplementary blended flour based on chickpea and cereals for the treatment of infants with moderate acute malnutrition in Iran: A randomized clinical trial

Effectiveness of supplementary blended flour based on chickpea and cereals for the treatment of infants with moderate acute malnutrition in Iran: A randomized clinical trial Electronic Physician (ISSN: 2008-5842) http://www.ephysician.ir December 2017, Volume: 9, Issue: 12, Pages: 6078-6086, DOI: http://dx.doi.org/10.19082/6078 Corresponding author: Assistant Professor Dr. Mahdi Yousefi, Department of Persian Medicine, Faculty of Persian and Complementary Medicine, Mashhad University of Medical (...) in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. Page 6078 Effectiveness of supplementary blended flour based on chickpea and cereals for the treatment of infants with moderate acute malnutrition in Iran: A randomized clinical trial Roghayeh Javan 1, 2 , Akram Kooshki 3 , Monavvar Afzalaghaee 4 , Mitra Aldaghi 5 , Mahdi Yousefi 6 1 MD-PhD of Persian Medicine, Assistant Professor, Traditional and Complementary Medicine

Electronic physician2017 Full Text: Link to full Text with Trip Pro

147. Endoscopic Treatment versus Shunting for Infant Hydrocephalus in Uganda.

Endoscopic Treatment versus Shunting for Infant Hydrocephalus in Uganda. BACKGROUND: Postinfectious hydrocephalus in infants is a major health problem in sub-Saharan Africa. The conventional treatment is ventriculoperitoneal shunting, but surgeons are usually not immediately available to revise shunts when they fail. Endoscopic third ventriculostomy with choroid plexus cauterization (ETV-CPC) is an alternative treatment that is less subject to late failure but is also less likely than shunting (...) to result in a reduction in ventricular size that might facilitate better brain growth and cognitive outcomes. METHODS: We conducted a randomized trial to evaluate cognitive outcomes after ETV-CPC versus ventriculoperitoneal shunting in Ugandan infants with postinfectious hydrocephalus. The primary outcome was the Bayley Scales of Infant Development, Third Edition (BSID-3), cognitive scaled score 12 months after surgery (scores range from 1 to 19, with higher scores indicating better performance

NEJM2017 Full Text: Link to full Text with Trip Pro

148. Association of US State Implementation of Newborn Screening Policies for Critical Congenital Heart Disease With Early Infant Cardiac Deaths.

Association of US State Implementation of Newborn Screening Policies for Critical Congenital Heart Disease With Early Infant Cardiac Deaths. Importance: In 2011, critical congenital heart disease was added to the US Recommended Uniform Screening Panel for newborns, but whether state implementation of screening policies has been associated with infant death rates is unknown. Objective: To assess whether there was an association between implementation of state newborn screening policies (...) for critical congenital heart disease and infant death rates. Design, Setting, and Participants: Observational study with group-level analyses. A difference-in-differences analysis was conducted using the National Center for Health Statistics' period linked birth/infant death data set files for 2007-2013 for 26 546 503 US births through June 30, 2013, aggregated by month and state of birth. Exposures: State policies were classified as mandatory or nonmandatory (including voluntary policies and mandates

JAMA2017 Full Text: Link to full Text with Trip Pro

149. Survival of very preterm infants admitted to neonatal care in England 2008-2014: time trends and regional variation

Survival of very preterm infants admitted to neonatal care in England 2008-2014: time trends and regional variation 28883097 2017 09 08 1468-2052 2017 Sep 07 Archives of disease in childhood. Fetal and neonatal edition Arch. Dis. Child. Fetal Neonatal Ed. Survival of very preterm infants admitted to neonatal care in England 2008-2014: time trends and regional variation. fetalneonatal-2017-312748 10.1136/archdischild-2017-312748 To analyse survival trends and regional variation for very preterm (...) infants admitted to neonatal care. All neonatal units in England. Infants born at 22+0-31+6 weeks+daysgestational age (GA) over 2008-2014 and admitted to neonatal care; published data for admitted infants 22+0-25+6 weeks+days GA in 1995 and 2006, and for live births at 22+0-31+6 weeks+days GA in 2013. We obtained data from the National Neonatal Research Database. We used logistic regression to model survival probability with birth weight, GA, sex, antenatal steroid exposure and multiple birth included

EvidenceUpdates2017 Full Text: Link to full Text with Trip Pro

150. Surgical Interventions in Infants Born Preterm with Congenital Heart Defects: An Analysis of the Kids` Inpatient Database

Surgical Interventions in Infants Born Preterm with Congenital Heart Defects: An Analysis of the Kids` Inpatient Database 28964428 2017 12 11 2017 12 11 1097-6833 191 2017 Dec The Journal of pediatrics J. Pediatr. Surgical Interventions in Infants Born Preterm with Congenital Heart Defects: An Analysis of the Kids' Inpatient Database. 103-109.e4 S0022-3476(17)30949-6 10.1016/j.jpeds.2017.07.015 To evaluate short-term outcomes in infants born preterm with congenital heart defects (CHDs (...) ) and the factors associated with surgery, survival, and length of hospitalization in this population. We analyzed data from infants born preterm (gestational age <37 weeks) enrolled in the multicenter Kids' Inpatient Database of the Healthcare Cost and Utilization Project who were admitted to the hospital within 30 days after birth. Infants with atrial septal defects were excluded. Of 1 429 762 enrolled infants born preterm, 27 434 (2.0%) with CHDs were included. Overall survival to discharge was 90.5%; 74.0

EvidenceUpdates2017

151. Effect of Inhaled Nitric Oxide on Survival Without Bronchopulmonary Dysplasia in Preterm Infants: A Randomized Clinical Trial

Effect of Inhaled Nitric Oxide on Survival Without Bronchopulmonary Dysplasia in Preterm Infants: A Randomized Clinical Trial 28973344 2017 11 20 2017 12 07 2168-6211 171 11 2017 Nov 01 JAMA pediatrics JAMA Pediatr Effect of Inhaled Nitric Oxide on Survival Without Bronchopulmonary Dysplasia in Preterm Infants: A Randomized Clinical Trial. 1081-1089 10.1001/jamapediatrics.2017.2618 Bronchopulmonary dysplasia (BPD) occurs in approximately 40% of infants born at younger than 30 weeks' gestation (...) and is associated with adverse pulmonary and neurodevelopmental outcomes. To test whether administration of inhaled nitric oxide to preterm infants requiring positive pressure respiratory support on postnatal days 5 to 14 improves the rate of survival without BPD. This intent-to-treat study was a randomized clinical trial performed at 33 US and Canadian neonatal intensive care units. Participants included 451 neonates younger than 30 weeks' gestation with birth weight less than 1250 g receiving mechanical

EvidenceUpdates2017

152. Crying Time and RORgamma/FOXP3 Expression in Lactobacillus reuteri DSM17938-Treated Infants with Colic: A Randomized Trial

Crying Time and RORgamma/FOXP3 Expression in Lactobacillus reuteri DSM17938-Treated Infants with Colic: A Randomized Trial 28969887 2017 12 16 1097-6833 192 2018 Jan The Journal of pediatrics J. Pediatr. Crying Time and RORγ/FOXP3 Expression in Lactobacillus reuteri DSM17938-Treated Infants with Colic: A Randomized Trial. 171-177.e1 S0022-3476(17)31143-5 10.1016/j.jpeds.2017.08.062 To evaluate crying time, retinoid-related orphan receptor-γ (RORγ) and forkhead box P3 (FOXP3) messenger RNA (...) levels (transcription factors that can modulate T cell responses to gut microbes), and to investigate gut microbiota and fecal calprotectin in infants treated with Lactobacillus reuteri for infantile colic. A double-blind, placebo-controlled randomized trial was conducted in primary care in Torino from August 1, 2015 to September 30, 2016. Patients suffering from infantile colic were randomly assigned to receive daily oral L reuteri (1 × 108 colony forming unit) or placebo for 1 month. Daily crying

EvidenceUpdates2017 Full Text: Link to full Text with Trip Pro

153. 2% chlorhexidine-70% isopropyl alcohol versus 10% povidone-iodine for insertion site cleaning before central line insertion in preterm infants: a randomised trial

2% chlorhexidine-70% isopropyl alcohol versus 10% povidone-iodine for insertion site cleaning before central line insertion in preterm infants: a randomised trial 29074717 2017 10 27 1468-2052 2017 Oct 26 Archives of disease in childhood. Fetal and neonatal edition Arch. Dis. Child. Fetal Neonatal Ed. 2% chlorhexidine-70% isopropyl alcohol versus 10% povidone-iodine for insertion site cleaning before central line insertion in preterm infants: a randomised trial. fetalneonatal-2016-312193 (...) 10.1136/archdischild-2016-312193 To determine whether 2% chlorhexidine gluconate-70% isopropyl alcohol (CHX-IA) is superior to 10% aqueous povidone-iodine (PI) in preventing catheter-related blood stream infection (CR-BSI) when used to clean insertion sites before placing central venous catheters (CVCs) in preterm infants. Randomised controlled trial. Two neonatal intensive care units (NICUs). Infants <31 weeks' gestation who had a CVC inserted. Insertion site was cleaned with CHX-IA or PI. Caregivers

EvidenceUpdates2017

154. Effect of MRI on preterm infants and their families: a randomised trial with nested diagnostic and economic evaluation

Effect of MRI on preterm infants and their families: a randomised trial with nested diagnostic and economic evaluation 28988160 2017 12 19 2017 12 19 1468-2052 103 1 2018 Jan Archives of disease in childhood. Fetal and neonatal edition Arch. Dis. Child. Fetal Neonatal Ed. Effect of MRI on preterm infants and their families: a randomised trial with nested diagnostic and economic evaluation. F15-F21 10.1136/archdischild-2017-313102 We tested the hypothesis that routine MRI would improve the care (...) and well-being of preterm infants and their families. Parallel-group randomised trial (1.1 allocation; intention-to-treat) with nested diagnostic and cost evaluations (EudraCT 2009-011602-42). Participants from 14 London hospitals, imaged at a single centre. 511 infants born before 33 weeks gestation underwent both MRI and ultrasound around term. 255 were randomly allocated (siblings together) to receive only MRI results and 255 only ultrasound from a paediatrician unaware of unallocated results; one

EvidenceUpdates2017 Full Text: Link to full Text with Trip Pro

155. Avoidance of Cow's Milk-Based Formula for At-Risk Infants Does Not Reduce Development of Celiac Disease: A Randomized Controlled Trial

Avoidance of Cow's Milk-Based Formula for At-Risk Infants Does Not Reduce Development of Celiac Disease: A Randomized Controlled Trial 28687275 2017 10 16 2017 10 16 1528-0012 153 4 2017 Oct Gastroenterology Gastroenterology Avoidance of Cow's Milk-Based Formula for At-Risk Infants Does Not Reduce Development of Celiac Disease: A Randomized Controlled Trial. 961-970.e3 S0016-5085(17)35862-6 10.1053/j.gastro.2017.06.049 Feeding during the first months of life might affect risk for celiac disease (...) . Individuals with celiac disease or type 1 diabetes have been reported to have high titers of antibodies against cow's milk proteins. Avoidance of cow's milk-based formula for infants with genetic susceptibility for type 1 diabetes reduced the cumulative incidence of diabetes-associated autoantibodies. We performed a randomized controlled trial in the same population to study whether weaning to an extensively hydrolyzed formula reduced the risk of celiac disease autoimmunity or celiac disease. We performed

EvidenceUpdates2017

156. Delirium and Benzodiazepines Associated With Prolonged ICU Stay in Critically Ill Infants and Young Children

Delirium and Benzodiazepines Associated With Prolonged ICU Stay in Critically Ill Infants and Young Children PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2017

157. Improving postpartum care delivery and uptake by implementing context-specific interventions in four countries in Africa: a realist evaluation of the Missed Opportunities in Maternal and Infant Health (MOMI) project

Improving postpartum care delivery and uptake by implementing context-specific interventions in four countries in Africa: a realist evaluation of the Missed Opportunities in Maternal and Infant Health (MOMI) project 1 Djellouli N, et al. BMJ Glob Health 2017;2:e000408. doi:10.1136/bmjgh-2017-000408 Abstr Act Postpartum care (PPC) has remained relatively neglected in many interventions designed to improve maternal and neonatal health in sub-Saharan Africa. The Missed Opportunities in Maternal (...) and Infant Health project developed and implemented a context-specific package of health system strengthening and demand generation in four African countries, aiming to improve access and quality of PPC. A realist evaluation was conducted to enable nuanced understanding of the influence of different contextual factors on both the implementation and impacts of the interventions. Mixed methods were used to collect data and test hypothesised context–mechanism–outcome configurations: 16 case studies

BMJ global health2017 Full Text: Link to full Text with Trip Pro

158. Early erythropoiesis-stimulating agents in preterm or low birth weight infants.

Early erythropoiesis-stimulating agents in preterm or low birth weight infants. BACKGROUND: Preterm infants have low plasma levels of erythropoietin (EPO), providing a rationale for the use of erythropoiesis-stimulating agents (ESAs) to prevent or treat anaemia and to provide neuro protection and protection against necrotising enterocolitis (NEC). Darbepoetin (Darbe) and EPO are currently available ESAs. OBJECTIVES: To assess the effectiveness and safety of ESAs (erythropoietin (EPO (...) ) and/or Darbe) initiated early (before eight days after birth) compared with placebo or no intervention in reducing red blood cell (RBC) transfusions, adverse neurological outcomes, and feeding intolerance including necrotising enterocolitis (NEC) in preterm and/or low birth weight infants. Primary objective for studies that primarily investigate the effectiveness and safety of ESAs administered early in reducing red blood cell transfusions:To assess the effectiveness and safety of ESAs initiated early

Cochrane2017

159. Mesenchymal stem cells for the prevention and treatment of bronchopulmonary dysplasia in preterm infants.

Mesenchymal stem cells for the prevention and treatment of bronchopulmonary dysplasia in preterm infants. BACKGROUND: Bronchopulmonary dysplasia (BPD) remains a major complication of prematurity and currently lacks efficient treatments. Mesenchymal stem/stromal cells (MSCs) have been extensively explored as a potential therapy in several preclinical and clinical settings. Human and animal MSCs have been shown to prevent and treat lung injury in various preclinical models of lung diseases (...) , including experimental BPD. OBJECTIVES: To determine if MSCs, administered intravenously or endotracheally, are safe and effective in preventing or treating BPD, or both, in preterm infants. SEARCH METHODS: We used the standard search strategy of the Cochrane Neonatal Review Group to search the Cochrane Central Register of Controlled Trials (CENTRAL 2016, Issue 10), MEDLINE via PubMed (1966 to 6 November 2016), Embase (1980 to 6 November 2016), and CINAHL (1982 to 6 November 2016). We also searched

Cochrane2017

160. Transcatheter atrial septal defect closure in an infant (body weight 6.4 kg) using the GORE CARDIOFORM septal occluder (GCSO)

Transcatheter atrial septal defect closure in an infant (body weight 6.4 kg) using the GORE CARDIOFORM septal occluder (GCSO) 29101573 2018 11 13 2194-7791 4 1 2017 Nov 03 Molecular and cellular pediatrics Mol Cell Pediatr Transcatheter atrial septal defect closure in an infant (body weight 6.4 kg) using the GORE CARDIOFORM septal occluder (GCSO). 9 10.1186/s40348-017-0077-7 Transcatheter closure has become the treatment of choice for secundum atrial septal defects (ASD II), but particularly (...) in small children, there is concern regarding procedure-related complications. We report on a 10-month-old infant, body weight of 6.4 kg, with a large ASD who was referred for failure to thrive and dyspnea on exertion. Echocardiography showed two neighboring ASDs centrally located within an atrial septum with a length of 27 mm resulting in significant left-to-right shunting. During cardiac catheterization, hemodynamic significance of the defect as well as normal pulmonary vascular resistance

Molecular and cellular pediatrics2017 Full Text: Link to full Text with Trip Pro