Latest & greatest articles for infants

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Top results for infants

41. A modified developmental care bundle reduces pain and stress in preterm infants undergoing examinations for retinopathy of prematurity: A randomised controlled trial

A modified developmental care bundle reduces pain and stress in preterm infants undergoing examinations for retinopathy of prematurity: A randomised controlled trial 30091495 2018 09 04 1365-2702 2018 Aug 09 Journal of clinical nursing J Clin Nurs A modified developmental care bundle reduces pain and stress in preterm infants undergoing examinations for retinopathy of prematurity: A randomised controlled trial. 10.1111/jocn.14645 To determine the comparative efficacy of developmental care (...) versus standard care for reducing pain and stress in preterm infants during examinations for retinopathy of prematurity (ROP). ROP examinations are routinely performed in neonatal intensive care units to detect these lesions. Pain scores recorded during and after eye examinations have revealed physiological and behavioural manifestations of pain and stress. A randomised crossover trial was conducted. Fourteen preterm infants were evaluated. The modified developmental care bundle included

EvidenceUpdates2018

42. The Effect of Noninvasive High-Frequency Oscillatory Ventilation on Desaturations and Bradycardia in Very Preterm Infants: A Randomized Crossover Trial

The Effect of Noninvasive High-Frequency Oscillatory Ventilation on Desaturations and Bradycardia in Very Preterm Infants: A Randomized Crossover Trial 29954606 2018 06 29 1097-6833 2018 Jun 25 The Journal of pediatrics J. Pediatr. The Effect of Noninvasive High-Frequency Oscillatory Ventilation on Desaturations and Bradycardia in Very Preterm Infants: A Randomized Crossover Trial. S0022-3476(18)30742-X 10.1016/j.jpeds.2018.05.029 Noninvasive high-frequency oscillatory ventilation compared (...) with nasal continuous positive airway pressure significantly reduced the number of desaturations and bradycardia in preterm infants. However, noninvasive high-frequency oscillatory ventilation was associated with increased oxygen requirements and higher heart rates. Australian and New Zealand Clinical Trial Registry: ACTRN12616001516471. Copyright © 2018 Elsevier Inc. All rights reserved. Rüegger Christoph M CM Newborn Research Center and Neonatal Services, The Royal Women's Hospital, Melbourne, Victoria

EvidenceUpdates2018

43. Cord milking versus immediate clamping in preterm infants: a randomised controlled trial

Cord milking versus immediate clamping in preterm infants: a randomised controlled trial 29903720 2018 06 15 1468-2052 2018 Jun 14 Archives of disease in childhood. Fetal and neonatal edition Arch. Dis. Child. Fetal Neonatal Ed. Cord milking versus immediate clamping in preterm infants: a randomised controlled trial. fetalneonatal-2018-314757 10.1136/archdischild-2018-314757 To investigate whether umbilical cord milking (UCM) at birth improves systemic blood flow and short-term outcomes (...) , as compared with immediate cord clamping (ICC). Randomised clinical trial. Single tertiary care centre. Infants born to eligible women presenting in preterm labour between 24 and 31 weeks' gestation. UCM three times at birth or ICC. Primary outcome included systemic blood flow as represented by echo-derived superior vena cava(SVC) flow at 4-6 hours after birth. The echocardiographer and interpreter were blinded to the randomisation. Secondary outcomes included cardiac output, neonatal morbidities

EvidenceUpdates2018

44. Oral thyroxin supplementation in infants undergoing cardiac surgery: A double-blind placebo-controlled randomized clinical trial

Oral thyroxin supplementation in infants undergoing cardiac surgery: A double-blind placebo-controlled randomized clinical trial 30119284 2018 08 18 1097-685X 156 3 2018 Sep The Journal of thoracic and cardiovascular surgery J. Thorac. Cardiovasc. Surg. Oral thyroxin supplementation in infants undergoing cardiac surgery: A double-blind placebo-controlled randomized clinical trial. 1209-1217.e3 S0022-5223(18)31466-1 10.1016/j.jtcvs.2018.05.044 Decreases in serum total thyroxin and total (...) triiodothyronine occurs after cardiopulmonary bypass, and is reflected as poor immediate outcome. We studied effects of oral thyroxin supplementation in infants who underwent open-heart surgery. In this prospective study, 100 patients were randomized into 2 groups: 50 in the thyroxin group (TH) and 50 in the placebo group (PL). Patients in the TH group received oral thyroxin (5 μg/kg) 12 hours before surgery and once daily for the remainder of their intensive care unit (ICU) stay. Data on intraoperative

EvidenceUpdates2018

45. Association of Early Introduction of Solids With Infant Sleep: A Secondary Analysis of a Randomized Clinical Trial

Association of Early Introduction of Solids With Infant Sleep: A Secondary Analysis of a Randomized Clinical Trial 29987321 2018 08 08 2168-6211 172 8 2018 Aug 06 JAMA pediatrics JAMA Pediatr Association of Early Introduction of Solids With Infant Sleep: A Secondary Analysis of a Randomized Clinical Trial. e180739 10.1001/jamapediatrics.2018.0739 The World Health Organization recommends exclusive breastfeeding for 6 months. However, 75% of British mothers introduce solids before 5 months and 26 (...) % report infant waking at night as influencing this decision. To determine whether early introduction of solids influences infant sleep. The Enquiring About Tolerance study was a population-based randomized clinical trial conducted from January 15, 2008, to August 31, 2015, that included 1303 exclusively breastfed 3-month-old infants from England and Wales. Clinical visits took place at St Thomas' Hospital, London, England, and the trial studied the early introduction of solids into the infant diet

EvidenceUpdates2018

46. Lipid-based nutrient supplements for maternal, birth, and infant developmental outcomes.

Lipid-based nutrient supplements for maternal, birth, and infant developmental outcomes. BACKGROUND: Ready-to-use lipid-based nutrient supplements (LNS) are a highly nutrient-dense supplement, which could be a good source of macro- and micronutrients for pregnant women who need to supplement their nutrient intake. OBJECTIVES: To assess the effects of LNS for maternal, birth and infant outcomes in pregnant women. Secondary objectives were to explore the most appropriate composition, frequency (...) study (536 participants) showed a two-fold increase in the prevalence of maternal anaemia in the LNS group compared to the IFA group, but no difference between the groups as regards adverse effects. There was no difference between the two groups for maternal mortality (risk ratio (RR) 0.53, 95% CI 0.12 to 2.41; 3 studies, 5628 participants).Birth and infant outcomes: there was no difference between the LNS and IFA groups for low birth weight (LBW) (RR 0.87, 95% CI 0.72 to 1.05; 3 studies, 4826

Cochrane2018

47. Carbohydrate supplementation of human milk to promote growth in preterm infants.

Carbohydrate supplementation of human milk to promote growth in preterm infants. BACKGROUND: Preterm infants are born with low glycogen stores and require higher glucose intake to match fetal accretion rates. In spite of the myriad benefits of breast milk for preterm infants, it may not adequately meet the needs of these rapidly growing infants. Supplementing human milk with carbohydrates may help. However, there is a paucity of data on assessment of benefits or harms of carbohydrate (...) supplementation of human milk to promote growth in preterm infants. This is a 2018 update of a Cochrane Review first published in 1999. OBJECTIVES: To determine whether human milk supplemented with carbohydrate compared with unsupplemented human milk fed to preterm infants improves growth, body composition, and cardio-metabolic and neurodevelopmental outcomes without significant adverse effects. SEARCH METHODS: We used the standard search strategy of the Cochrane Neonatal Review Group to search the Cochrane

Cochrane2018

48. Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth.

Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth. Background It is unclear whether maternal vitamin D supplementation during pregnancy and lactation improves fetal and infant growth in regions where vitamin D deficiency is common. Methods We conducted a randomized, double-blind, placebo-controlled trial in Bangladesh to assess the effects of weekly prenatal vitamin D supplementation (from 17 to 24 weeks of gestation until birth) and postpartum vitamin D supplementation (...) on the primary outcome of infants' length-for-age z scores at 1 year according to World Health Organization (WHO) child growth standards. One group received neither prenatal nor postpartum vitamin D (placebo group). Three groups received prenatal supplementation only, in doses of 4200 IU (prenatal 4200 group), 16,800 IU (prenatal 16,800 group), and 28,000 IU (prenatal 28,000 group). The fifth group received prenatal supplementation as well as 26 weeks of postpartum supplementation in the amount of 28,000 IU

NEJM2018 Full Text: Link to full Text with Trip Pro

49. Updated recommendations on first-line and second-line antiretroviral regimens and post-exposure prophylaxis and recommendations on early infant diagnosis of HIV: interim guidance

Updated recommendations on first-line and second-line antiretroviral regimens and post-exposure prophylaxis and recommendations on early infant diagnosis of HIV: interim guidance UPDATED RECOMMENDATIONS ON FIRST-LINE AND SECOND-LINE ANTIRETROVIRAL REGIMENS AND POST-EXPOSURE PROPHYLAXIS AND RECOMMENDATIONS ON EARLY INFANT DIAGNOSIS OF HIV JULY 2018 POLICY BRIEF HIV TREATMENT – INTERIM GUIDANCE @WHO/SEARO Gary HamptonWHO/CDS/HIV/18.18 © World Health Organization 2018 Some rights reserved (...) the licence shall be conducted in accordance with the mediation rules of the World Intellectual Property Organization. Suggested citation. Updated recommendations on first-line and second-line antiretroviral regimens and post-exposure prophylaxis and recommendations on early infant diagnosis of HIV: interim guidance. Geneva: World Health Organization; 2018 (WHO/CDS/HIV/18.18). Licence: CC BY-NC-SA 3.0 IGO. Cataloguing-in-Publication (CIP) data. CIP data are available at http://apps.who.int/iris. Sales

World Health Organisation HIV Guidelines2018

50. Best Practices on Periodicity of Examination, Preventive Dental Services, Anticipatory Guidance/Counseling, and Oral Treatment for Infants, Children, and Adolescents

Best Practices on Periodicity of Examination, Preventive Dental Services, Anticipatory Guidance/Counseling, and Oral Treatment for Infants, Children, and Adolescents 194 RECOMMENDATIONS: BEST PRACTICES REFERENCE MANUAL V 40 / NO 6 18 / 19 Review Council Council on Clinical Affairs Latest Revision 2018 Periodicity of Examination, Preventive Dental Services, Anticipatory Guidance/Counseling, and Oral T reatment for Infants, Children, and Adolescents ABBREVIATIONS AAPD: American Academy Pediatric (...) Dentistry. ECC: Early child- hood caries. SHCN: Special health care needs. Purpose The American Academy of Pediatric Dentistry (AAPD) intends these recommendations to help practitioners make clinical decisions concerning preventive oral health inter- ventions, including anticipatory guidance and preventive counseling, for infants, children, and adolescents. Methods This document was developed by the Clinical Affairs Committee and adopted in 1991. This document is a revision of the previous version, last

American Academy of Pediatric Dentistry2018

51. Best Practices for Pain Management in Infants, Children, Adolescents, and Individuals with Special Health Care Needs

Best Practices for Pain Management in Infants, Children, Adolescents, and Individuals with Special Health Care Needs AMERICAN ACADEMY OF PEDIATRIC DENTISTRY RECOMMENDATIONS: BEST PRACTICES 321 Purpose The American Academy of Pediatric Dentistry ( AAPD) recognizes that infants, children, adolescents, and individuals with special health care needs can and do experience pain due to dental/orofacial injury, infection, and dental procedures, and that inadequate pain management may have significant (...) nervous system. FDA: Food and Drug Administration. IV: Intravenous. NSAIDs: Nonsteroidal anti-inflammatory drugs. VAS: Visual analogue scale. Pain Management in Infants, Children, Adolescents and Individuals with Special Health Care Needs322 RECOMMENDATIONS: BEST PRACTICES REFERENCE MANUAL V 40 / NO 6 18 / 19 the area of tissue damage, and allodynia, which refers to pain perception following innocuous stimuli such as light touch, are characteristics of central sensitization. 13 Pain modulation Modulation of pain

American Academy of Pediatric Dentistry2018

52. Thermal Effect of a Woolen Cap in Low Birth Weight Infants During Kangaroo Care

Thermal Effect of a Woolen Cap in Low Birth Weight Infants During Kangaroo Care 29789445 2018 06 02 1098-4275 141 6 2018 Jun Pediatrics Pediatrics Thermal Effect of a Woolen Cap in Low Birth Weight Infants During Kangaroo Care. e20173073 10.1542/peds.2017-3073 World Health Organization guidelines recommend covering the head during kangaroo mother care (KMC), but the effect of a cap on neonatal thermal control during KMC remains to be defined. Our objective was to assess the effectiveness (...) and safety of a woolen cap in maintaining low birth weight infants (LBWIs) in normal thermal range during KMC. Three hundred LBWI candidates for KMC in 3 African hospitals were randomly assigned to KMC with (CAP group) or without (NOCAP group) a woolen cap in a 1:1 ratio during the first week after birth. Axillary temperature was measured every 6 hours. Maternal and room temperature and adherence to skin-to-skin contact were registered at the same time points. A total number of 5064 measurements were

EvidenceUpdates2018

53. Efficacy of facilitated tucking combined with non-nutritive sucking on very preterm infants` pain during the heel-stick procedure: A randomized controlled trial

Efficacy of facilitated tucking combined with non-nutritive sucking on very preterm infants` pain during the heel-stick procedure: A randomized controlled trial 29960105 2018 08 17 1873-491X 86 2018 Jun 15 International journal of nursing studies Int J Nurs Stud Efficacy of facilitated tucking combined with non-nutritive sucking on very preterm infants' pain during the heel-stick procedure: A randomized controlled trial. 29-35 S0020-7489(18)30145-7 10.1016/j.ijnurstu.2018.06.007 Reducing acute (...) pain in premature infants during neonatal care improves their neurophysiological development. The use of pharmacological and non-pharmacological analgesia, such as sucrose, is limited per day, particularly for very preterm infants. Thus, the usual practice of non-nutritive sucking is often used alone. Facilitated tucking could be an additional strategy to non-nutritive sucking for reducing pain. To the best of our knowledge, no randomized trial has compared the combination of facilitated tucking

EvidenceUpdates2018

54. Association between Furosemide Exposure and Patent Ductus Arteriosus in Hospitalized Infants of Very Low Birth Weight

Association between Furosemide Exposure and Patent Ductus Arteriosus in Hospitalized Infants of Very Low Birth Weight 29752171 2018 08 01 1097-6833 199 2018 Aug The Journal of pediatrics J. Pediatr. Association between Furosemide Exposure and Patent Ductus Arteriosus in Hospitalized Infants of Very Low Birth Weight. 231-236 S0022-3476(18)30479-7 10.1016/j.jpeds.2018.03.067 To evaluate the association between furosemide exposure and patent ductus arteriosus (PDA) in a large, contemporary cohort (...) of hospitalized infants with very low birth weight (VLBW). Using the Pediatrix Medical Group Clinical Data Warehouse, we identified all inborn infants of VLBW <37 weeks of gestation discharged from the neonatal intensive care unit after the first postnatal week from 2011 to 2015. We defined PDA as any medical (ibuprofen or indomethacin) or surgical PDA therapy. We collected data up to the day of PDA treatment or postnatal day 18 for infants not diagnosed with PDA. We performed multivariable logistic

EvidenceUpdates2018

55. Infants

Infants Top results for infants - Trip Database or use your Google+ account Liberating the literature My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search (...) button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for infants The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory

Trip Latest and Greatest2018

56. Sudden vs Pressure Wean From Nasal Continuous Positive Airway Pressure in Infants Born Before 32 Weeks of Gestation: A Randomized Clinical Trial

Sudden vs Pressure Wean From Nasal Continuous Positive Airway Pressure in Infants Born Before 32 Weeks of Gestation: A Randomized Clinical Trial 30039171 2018 07 24 2168-6211 2018 Jul 23 JAMA pediatrics JAMA Pediatr Sudden vs Pressure Wean From Nasal Continuous Positive Airway Pressure in Infants Born Before 32 Weeks of Gestation: A Randomized Clinical Trial. 10.1001/jamapediatrics.2018.2074 Nasal continuous positive airway pressure (nCPAP) is a well-established treatment of respiratory (...) distress syndrome in preterm infants. Suboptimal weaning from nCPAP may be associated with lung injury, pulmonary morbidity, and infant weight gain. To our knowledge, the best weaning strategy from nCPAP is unknown. To compare the effect of sudden wean and pressure wean from nCPAP in very preterm infants. A randomized, clinical, open-label, multicenter trial was conducted at 6 neonatal intensive care units in Denmark from September 2012 to December 2016 and included infants born before 32 weeks of gestation. Sudden wean

EvidenceUpdates2018

57. Procedural Pain during Insertion of a Continuous Glucose Monitoring Device in Preterm Infants

Procedural Pain during Insertion of a Continuous Glucose Monitoring Device in Preterm Infants 29861315 2018 06 04 1097-6833 2018 May 31 The Journal of pediatrics J. Pediatr. Procedural Pain during Insertion of a Continuous Glucose Monitoring Device in Preterm Infants. S0022-3476(18)30387-1 10.1016/j.jpeds.2018.03.040 Procedural pain was compared between the insertion of a continuous glucose monitoring sensor and heel stick using the Premature Infant Pain Profile in a single-blinded controlled (...) trial in preterm infants (≤32 weeks of gestation or birth weight ≤1500 g) (ClinicalTrials.govNCT02583776). Continuous glucose monitoring insertion was associated with lower pain scores compared with the heel stick. Copyright © 2018 Elsevier Inc. All rights reserved. Galderisi Alfonso A Neonatal Intensive Care Unit, Department of Women and Children's Health, University of Padova, Padova, Italy; Department of Pediatrics, Yale University, New Haven, CT. Electronic address: alfonso.galderisi@yale.edu

EvidenceUpdates2018

58. Gastric Residual Volume in Feeding Advancement in Preterm Infants (GRIP Study): A Randomized Trial

Gastric Residual Volume in Feeding Advancement in Preterm Infants (GRIP Study): A Randomized Trial 29866595 2018 06 05 1097-6833 2018 Jun 01 The Journal of pediatrics J. Pediatr. Gastric Residual Volume in Feeding Advancement in Preterm Infants (GRIP Study): A Randomized Trial. S0022-3476(18)30626-7 10.1016/j.jpeds.2018.04.072 To evaluate the effect of not relying on prefeeding gastric residual volumes to guide feeding advancement on the time to reach full feeding volumes in preterm infants (...) , compared with routine measurement of gastric residual volumes. We hypothesized that not measuring prefeeding gastric residual volumes can shorten the time to reach full feeds. In this single-center, randomized, controlled trial, we included gavage fed preterm infants with birth weights (BW) 1500-2000 g who were enrolled within 48 hours of birth. Exclusion criteria were major congenital malformations, asphyxia, and BW below the third percentile. In the study group, the gastric residual volume

EvidenceUpdates2018

59. Metformin for women who are overweight or obese during pregnancy for improving maternal and infant outcomes.

Metformin for women who are overweight or obese during pregnancy for improving maternal and infant outcomes. BACKGROUND: There has been considerable interest in providing antenatal dietary and lifestyle advice for women with obesity or who are overweight during pregnancy, as a strategy to limit gestational weight gain and improve maternal and infant health. However, such antenatal interventions appear to have a modest effect on gestational weight gain and other clinical pregnancy and birth (...) women with obesity or who are overweight, acting to reduce glucose production in the liver and improve glucose uptake in smooth muscle cells, and therefore improve the overall metabolic health of women in pregnancy and reduce the risk of known adverse pregnancy outcomes. OBJECTIVES: To evaluate the role of metformin in pregnant women with obesity or who are overweight, on maternal and infant outcomes, including adverse effects of treatment and costs. SEARCH METHODS: We searched Cochrane Pregnancy

Cochrane2018

60. Minimally invasive perventricular versus open surgical ventricular septal defect closure in infants and children: a randomised clinical trial

Minimally invasive perventricular versus open surgical ventricular septal defect closure in infants and children: a randomised clinical trial 29941505 2018 06 29 1468-201X 2018 Jun 25 Heart (British Cardiac Society) Heart Minimally invasive perventricular versus open surgical ventricular septal defect closure in infants and children: a randomised clinical trial. heartjnl-2017-312793 10.1136/heartjnl-2017-312793 Robust evidence is lacking regarding the clinical efficacy, safety (...) and cardiopulmonary performance of perventricular closure. This study investigated the perioperative efficacy, safety and cardiorespiratory performance of perventricular closure of perimembranous ventricular septal defects (pmVSDs). Operation-naïve infants and young children aged 5-60 months with isolated pmVSDs were randomised to receive either standard open surgical or minimally invasive perventricular closure via direct entry into the ventricle with a catheter from a subxiphoid incision. The primary outcomes

EvidenceUpdates2018