Latest & greatest articles for ibuprofen

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Top results for ibuprofen

1. Efficacy and safety of ibuprofen and acetaminophen in children and adults: a meta-analysis and qualitative review

Efficacy and safety of ibuprofen and acetaminophen in children and adults: a meta-analysis and qualitative review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2010 DARE.

2. Paracetamol plus ibuprofen reduced fever in young children faster than paracetamol alone but not ibuprofen alone

Paracetamol plus ibuprofen reduced fever in young children faster than paracetamol alone but not ibuprofen alone Paracetamol plus ibuprofen reduced fever in young children faster than paracetamol alone but not ibuprofen alone | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Paracetamol plus ibuprofen reduced fever in young children faster than paracetamol alone but not ibuprofen alone Article Text Therapeutics Paracetamol plus ibuprofen

2009 Evidence-Based Medicine (Requires free registration)

3. Randomized comparative trial of efficacy of paracetamol, ibuprofen and paracetamol-ibuprofen combination for treatment of febrile children. (Full text)

Randomized comparative trial of efficacy of paracetamol, ibuprofen and paracetamol-ibuprofen combination for treatment of febrile children. Paracetamol and ibuprofen are widely used for fever in children as monotherapy and as combined therapy. None of the treatments is proven clearly superior to others. Hence, the study was planned to compare the efficacy of paracetamol, ibuprofen and paracetamol-ibuprofen combination for treatment of febrile children.This was an investigator blind, randomized (...) , comparative, parallel clinical trial conducted in 99 febrile children, 6 months to 12 years of age, allocated to three groups. First group received paracetamol 15 mg/kg, second group received ibuprofen 10 mg/kg and third group received both paracetamol and ibuprofen, all as a single dose by the oral route. Patients were followed-up at intervals of 1, 2, 3 and 4 h post dose by tympanic thermometry.Mean tympanic temperature after 4 h of drug administration was significantly lower in the combination group

2014 Perspectives in clinical research PubMed

4. Paracetamol and Ibuprofen for the treatment of fever in children: the PITCH randomised controlled trial

Paracetamol and Ibuprofen for the treatment of fever in children: the PITCH randomised controlled trial Paracetamol and Ibuprofen for the treatment of fever in children: the PITCH randomised controlled trial Journals Library An error has occurred in processing the XML document An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website (...) search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} Study found that either ibuprofen alone, or ibuprofen and paracetamol together, both lowered fever quicker in young children who were unwell with fever, than using paracetamol alone. {{author}} {{($index An error has occurred in processing the XML document An error has occurred in processing the XML document {{metadata.Journal}} Volume

2009 NIHR HTA programme

5. 400 mg Ibuprofen/1000 mg Acetaminophen (Paracetamol) Is Suggested Effective Dosage for Ibuprofen/Acetaminophen Combination Therapy in Postoperative Pain Reduction

400 mg Ibuprofen/1000 mg Acetaminophen (Paracetamol) Is Suggested Effective Dosage for Ibuprofen/Acetaminophen Combination Therapy in Postoperative Pain Reduction UTCAT2994, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title 400 mg Ibuprofen/1000 mg Acetaminophen (Paracetamol) Is Suggested Effective Dosage for Ibuprofen/Acetaminophen Combination Therapy in Postoperative Pain Reduction Clinical Question In patients (...) receiving acetaminophen (paracetamol) and ibuprofen combination therapy, what is the effective dosage to relieve postoperative pain? Clinical Bottom Line For patients with postoperative pain, 400 mg ibuprofen/1000 mg acetaminophen (paracetamol) is the suggested effective dosage for short-term pain management. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Mehlisch/2010 234 patients post extraction

2016 UTHSCSA Dental School CAT Library

6. Systematic review of studies comparing combined treatment with paracetamol and ibuprofen, with either drug alone (Full text)

Systematic review of studies comparing combined treatment with paracetamol and ibuprofen, with either drug alone Systematic review of studies comparing combined treatment with paracetamol and ibuprofen, with either drug alone Systematic review of studies comparing combined treatment with paracetamol and ibuprofen, with either drug alone Purssell E CRD summary The author concluded there was little evidence of benefit or harm from paracetamol and ibuprofen combined compared to using each alone (...) ; there was no evidence of increased toxicity. Due to the relatively small size and number of studies, imperfections in the conduct of the review, uncertain study quality and limited comparability of the studies, reliability of the conclusions is unclear. Authors' objectives To evaluate the evidence on paracetamol and ibuprofen combined to treat fever. Searching MEDLINE and EMBASE were searched up to May 2011. Guidelines from National Institute for Health and Clinical Excellence (NICE) on the treatment of fever

2011 DARE. PubMed

7. Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen

Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen Prescrire IN ENGLISH - Spotlight ''Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen'', 1 January 2016 {1} {1} {1} | | > > > Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |  (...)  |   |   |   |   |   |   |  Spotlight Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen When pain medication is required, paracetamol (alias acetaminophen) is the reference drug. Among the nonsteroidal anti-inflammatories (NSAIDs), naproxen or ibuprofen (not exceeding 1200 mg a day) are the drugs that carry the least exposure to cardiac disorders. When pain medication is needed

2016 Prescrire

8. Antipyretic Efficacy and Safety of Ibuprofen Versus Acetaminophen Suspension in Febrile Children: Results of 2 Randomized, Double-Blind, Single-Dose Studies. (PubMed)

Antipyretic Efficacy and Safety of Ibuprofen Versus Acetaminophen Suspension in Febrile Children: Results of 2 Randomized, Double-Blind, Single-Dose Studies. Two blinded single-dose studies randomized children 6 months to 11 years old with fever to receive ibuprofen (IBU) pediatric suspension 7.5 mg/kg or acetaminophen (APAP) suspension 10 to 15 mg/kg. The primary efficacy parameter was time-weighted sum of temperature differences (TWSTD) from baseline through 8 hours for each study. Secondary

2016 Clinical pediatrics

9. A comparative study of oral tramadol and ibuprofen in postoperative pain in operations of lower abdomen. (PubMed)

A comparative study of oral tramadol and ibuprofen in postoperative pain in operations of lower abdomen. The objective of this study was to assess efficacy and safety of oral tramadol in postoperative pain in operations of lower abdomen as compared to oral ibuprofen. Eighty patients undergoing operations in the lower abdomen under spinal anaesthesia were randomly assigned to two parallel groups--ibuprofen 400 mg thrice daily and tramadol 100 mg thrice daily, both orally after food. Treatment (...) was given single-blind for 5 days in the postoperative period. Patient's perception of pain scored byvisual analogue scale (VAS) and wound tenderness assessed by a 3-point ordinal scale were the primary efficacy parameters. A steady decline in VAS pain score from baseline to study end (99.7 +/- 2.75 to 54.4 +/- 9.71 in the ibuprofen group and 97.3 +/- 3.14 to 52.5 +/- 9.95 in tramadol group) indicated good analgesic efficacy in both groups. Within groups, comparisons showed highly significant difference

2011 Journal of the Indian Medical Association

10. Systematic review and meta-analysis of the clinical safety and tolerability of ibuprofen compared with paracetamol in paediatric pain and fever

Systematic review and meta-analysis of the clinical safety and tolerability of ibuprofen compared with paracetamol in paediatric pain and fever Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

11. Ibuprofen plus paracetamol versus ibuprofen in acute low back pain: a randomized open label multicenter clinical study. (PubMed)

Ibuprofen plus paracetamol versus ibuprofen in acute low back pain: a randomized open label multicenter clinical study. to estimate whether combination of ibuprofen and paracetamol is more effective than ibuprofen in monotherapy, in the treatment of acute low back pain.80 adult patients with acute low back pain were randomized into two subgroups. In the first subgroup, 40 patients were treated with ibuprofen 400mg three times a day (TID), whilst patients in the second subgroup (n=40) were (...) treated with a fixed-dose combination tablet of ibuprofen 200mg plus paracetamol 325mg TID, for three consecutive days. Patients were followed for another 7 days. Efficacy and tolerability of both treatment options was assessed.A statistically significant decrease in pain intensity, assessed using a visual analogue scale (p<0.001), as well as the 5-point Likert scale, was noticed in both subgroups of patients. However, intensity of pain on Day 4 was significantly lower in patients treated

2016 Acta reumatologica portuguesa

12. Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis. (Full text)

Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis. Despite increasing emphasis on conservative management of patent ductus arteriosus (PDA) in preterm infants, different pharmacotherapeutic interventions are used to treat those developing a hemodynamically significant PDA.To estimate the relative likelihood of hemodynamically significant PDA closure (...) with common pharmacotherapeutic interventions and to compare adverse event rates.The databases of MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials were searched from inception until August 15, 2015, and updated on December 31, 2017, along with conference proceedings up to December 2017. Randomized clinical trials that enrolled preterm infants with a gestational age younger than 37 weeks treated with intravenous or oral indomethacin, ibuprofen, or acetaminophen vs each other, placebo

2018 JAMA PubMed

13. Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis. (Full text)

Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis. The cardiovascular safety of celecoxib, as compared with nonselective nonsteroidal antiinflammatory drugs (NSAIDs), remains uncertain.Patients who required NSAIDs for osteoarthritis or rheumatoid arthritis and were at increased cardiovascular risk were randomly assigned to receive celecoxib, ibuprofen, or naproxen. The goal of the trial was to assess the noninferiority of celecoxib with regard to the primary composite (...) group (852±103 mg), or the ibuprofen group (2045±246 mg) for a mean treatment duration of 20.3±16.0 months and a mean follow-up period of 34.1±13.4 months. During the trial, 68.8% of the patients stopped taking the study drug, and 27.4% of the patients discontinued follow-up. In the intention-to-treat analyses, a primary outcome event occurred in 188 patients in the celecoxib group (2.3%), 201 patients in the naproxen group (2.5%), and 218 patients in the ibuprofen group (2.7%) (hazard ratio

2016 NEJM PubMed

14. Ketoprofen versus paracetamol (acetaminophen) or ibuprofen in the management of fever: results of two randomized, double-blind, double-dummy, parallel-group, repeated-dose, multicentre, phase III studies in children. (PubMed)

Ketoprofen versus paracetamol (acetaminophen) or ibuprofen in the management of fever: results of two randomized, double-blind, double-dummy, parallel-group, repeated-dose, multicentre, phase III studies in children. Fever is a common symptom in children and one of the major concerns of parents of younger and preschool-age children. To compare the efficacy and safety of ketoprofen with that of paracetamol (acetaminophen) and ibuprofen in the treatment of febrile conditions in children. Two (...) prospective, randomized, double-blind, double-dummy, repeated-dose, multicentre, phase III studies with two parallel groups in each study were conducted in primary-care outpatient clinics. Children aged 6 months to 6 years presenting with a febrile condition and an oral body temperature of > or =38.8 degrees C or rectal temperature of > or =39 degrees C were eligible for inclusion. Patients were randomized to receive either ketoprofen syrup 0.5 mg/kg, ibuprofen suspension 5 mg/kg or paracetamol suspension

2010 Clinical drug investigation

15. Ibuprofen, Acetaminophen and Dipyrone to Fever Control in Children

Ibuprofen, Acetaminophen and Dipyrone to Fever Control in Children Ibuprofen, Acetaminophen and Dipyrone to Fever Control in Children - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Ibuprofen, Acetaminophen (...) Farmaceutica Ltd. Study Details Study Description Go to Brief Summary: The purpose of this study was to compare the efficacy and tolerability of acetaminophen, dipyrone and ibuprofen to fever control in children. For the efficacy asses were compared: the time to start the action; the action duration; the difference between the basal temperature and the lower temperature in the study period. For the tolerability asses all adverse events were recorded, as well as your intensity and the relation

2011 Clinical Trials

16. Efficacy of celecoxib versus ibuprofen for the treatment of patients with osteoarthritis of the knee: A randomized double-blind, non-inferiority trial. (Full text)

Efficacy of celecoxib versus ibuprofen for the treatment of patients with osteoarthritis of the knee: A randomized double-blind, non-inferiority trial. Objective To compare the efficacy and tolerability of celecoxib and ibuprofen for the treatment of knee osteoarthritis symptoms. Method In this 6-week, multicentre, double-blind, non-inferiority trial, patients were randomized to 200 mg celecoxib once daily, 800 mg ibuprofen three times daily or placebo. The primary outcome was non-inferiority (...) of celecoxib to ibuprofen in Patient's Assessment of Arthritis Pain (scored 0-100). Secondary outcomes included the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index, Pain Satisfaction Scale, and upper gastrointestinal tolerability. Results A total of 388 patients were treated (celecoxib n = 153; ibuprofen n = 156; placebo n = 79). Mean difference (95% confidence interval) between celecoxib and ibuprofen in the Patient's Assessment of Arthritis Pain was 2.76 (-3.38, 8.90). As the lower

2017 The Journal of international medical research PubMed

17. Combination Therapy of Acetaminophen and Ibuprofen Is the Most Effective Treatment for Patients with Post-Endodontic Pain

Combination Therapy of Acetaminophen and Ibuprofen Is the Most Effective Treatment for Patients with Post-Endodontic Pain UTCAT3197, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Combination Therapy of Acetaminophen and Ibuprofen Is the Most Effective Treatment for Patients with Post-Endodontic Pain Clinical Question In patients with post-operative endodontic pain, does the combination of non-steroidal anti (...) -inflammatory drugs (NSAIDs) with acetaminophen provide more pain relief than individual NSAIDs or acetaminophen or placebo? Clinical Bottom Line For patients with post-operative endodontic pain, post-operative combination therapy of ibuprofen and acetaminophen provides more pain relief than acetaminophen alone or placebo. Acetaminophen alone did not provide more post-operative endodontic pain relief than placebo, suggesting that acetaminophen should only be used in combination with other NSAIDs for post

2017 UTHSCSA Dental School CAT Library

18. Ibuprofen

Ibuprofen Top results for ibuprofen - Trip Database or use your Google+ account Liberating the literature ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 (...) or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for ibuprofen The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence

2018 Trip Latest and Greatest

19. Treating fever in children: paracetamol or ibuprofen?

Treating fever in children: paracetamol or ibuprofen? Treating fever in children: paracetamol or ibuprofen? Treating fever in children: paracetamol or ibuprofen? Purssell E Authors' objectives To compare the effectiveness of paracetamol and ibuprofen as antipyretic medications for children. Searching MEDLINE, EMBASE, CINAHL and the Royal College of Nursing database were searched from 1970. The keywords used were ('children' or 'infants' or 'paediatric' or 'pediatric') and ('fever' or 'febrile (...) ' or 'pyrexia' or ' temperature') and ('paracetamol' or 'acetaminophen') and 'ibuprofen'. Textbooks and reference lists were also searched. Study selection Study designs of evaluations included in the review Studies that reported sufficient statistics to allow the calculation of effect size were eligible. The included studies were randomised controlled trials (RCTs), including double-blind RCTs, and controlled trials in which it was unclear whether they were randomised or not. Specific interventions

2002 DARE.

20. Efficacy and safety of acetaminophen vs ibuprofen for treating children's pain or fever: a meta-analysis. (Full text)

Efficacy and safety of acetaminophen vs ibuprofen for treating children's pain or fever: a meta-analysis. To summarize studies testing the efficacy and safety of single-dose acetaminophen and ibuprofen for treating children's pain or fever.Reports were gathered by searching computerized databases (from their inception through May 2002) and registries, relevant journals, and bibliographies of key articles.Seventeen blinded, randomized controlled trials with children (<18 years) receiving either (...) drug to treat fever or moderate to severe pain.Under a fixed-effects model, outcome measures for an initial single dose of ibuprofen vs acetaminophen were the risk ratio for achieving more than 50% of maximum pain relief, effect size for febrile temperature reduction, and risk ratio for minor and major harm.Ibuprofen (4-10 mg/kg) and acetaminophen (7-15 mg/kg) showed comparable efficacy (3 pain relief trials; 186 children). The risk ratio point estimates was 1.14 (95%confidence interval [CI], 0.82

2004 Archives of Pediatrics & Adolescent Medicine PubMed