Latest & greatest articles for ibuprofen

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Top results for ibuprofen

1. Ibuprofen

Ibuprofen Top results for ibuprofen - Trip Database or use your Google+ account Liberating the literature ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 (...) or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for ibuprofen The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence

2018 Trip Latest and Greatest

2. 400 mg Ibuprofen/1000 mg Acetaminophen (Paracetamol) Is Suggested Effective Dosage for Ibuprofen/Acetaminophen Combination Therapy in Postoperative Pain Reduction

400 mg Ibuprofen/1000 mg Acetaminophen (Paracetamol) Is Suggested Effective Dosage for Ibuprofen/Acetaminophen Combination Therapy in Postoperative Pain Reduction UTCAT2994, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title 400 mg Ibuprofen/1000 mg Acetaminophen (Paracetamol) Is Suggested Effective Dosage for Ibuprofen/Acetaminophen Combination Therapy in Postoperative Pain Reduction Clinical Question In patients (...) receiving acetaminophen (paracetamol) and ibuprofen combination therapy, what is the effective dosage to relieve postoperative pain? Clinical Bottom Line For patients with postoperative pain, 400 mg ibuprofen/1000 mg acetaminophen (paracetamol) is the suggested effective dosage for short-term pain management. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Mehlisch/2010 234 patients post extraction

2016 UTHSCSA Dental School CAT Library

3. Efficacy and safety of paracetamol and ibuprofen use for treatment of pain or fever in children under 2 years of age: protocol for a systematic review and meta-analysis

Efficacy and safety of paracetamol and ibuprofen use for treatment of pain or fever in children under 2 years of age: protocol for a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation

2019 PROSPERO

4. Paracetamol plus ibuprofen reduced fever in young children faster than paracetamol alone but not ibuprofen alone

Paracetamol plus ibuprofen reduced fever in young children faster than paracetamol alone but not ibuprofen alone Paracetamol plus ibuprofen reduced fever in young children faster than paracetamol alone but not ibuprofen alone | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Paracetamol plus ibuprofen reduced fever in young children faster than paracetamol alone but not ibuprofen alone Article Text Therapeutics Paracetamol plus ibuprofen

2009 Evidence-Based Medicine

5. Treating fever in children: paracetamol or ibuprofen? Full Text available with Trip Pro

Treating fever in children: paracetamol or ibuprofen? Treating fever in children: paracetamol or ibuprofen? Treating fever in children: paracetamol or ibuprofen? Purssell E Authors' objectives To compare the effectiveness of paracetamol and ibuprofen as antipyretic medications for children. Searching MEDLINE, EMBASE, CINAHL and the Royal College of Nursing database were searched from 1970. The keywords used were ('children' or 'infants' or 'paediatric' or 'pediatric') and ('fever' or 'febrile (...) ' or 'pyrexia' or ' temperature') and ('paracetamol' or 'acetaminophen') and 'ibuprofen'. Textbooks and reference lists were also searched. Study selection Study designs of evaluations included in the review Studies that reported sufficient statistics to allow the calculation of effect size were eligible. The included studies were randomised controlled trials (RCTs), including double-blind RCTs, and controlled trials in which it was unclear whether they were randomised or not. Specific interventions

2002 DARE.

6. Does Combination Treatment With Ibuprofen and Acetaminophen Improve Fever Control?

Does Combination Treatment With Ibuprofen and Acetaminophen Improve Fever Control? SystematicReviewSnapshot TAKE-HOME MESSAGE Combination treatment with ibuprofen and acetaminophen is bene?cial over either agent alone for sustained fever reduction in children older than 6 months. METHODS DATA SOURCES The author searched MEDLINE (1948 to May 2011) and EMBASE (1980 to May 2011). Additional hand searches of references from the UK National Institute for Health and Clinical Excellence guidelines (...) Standards of Re- porting Trials (CONSORT) crite- ria to score the quality of the included trials and abstract the data. Does Combination Treatment With Ibuprofen and Acetaminophen Improve Fever Control? EBEM Commentator Rohith R. Malya, MD, MSc Department of Emergency Medicine University of Texas at Houston Houston, TX Results Seventrialswereretrievedandallmet the inclusion criteria and most of the itemsontheCONSORTchecklist.Dif- ferences in dosing interval limited di- rect comparison between any 2

2013 Annals of Emergency Medicine Systematic Review Snapshots

7. Randomized comparative trial of efficacy of paracetamol, ibuprofen and paracetamol-ibuprofen combination for treatment of febrile children. Full Text available with Trip Pro

Randomized comparative trial of efficacy of paracetamol, ibuprofen and paracetamol-ibuprofen combination for treatment of febrile children. Paracetamol and ibuprofen are widely used for fever in children as monotherapy and as combined therapy. None of the treatments is proven clearly superior to others. Hence, the study was planned to compare the efficacy of paracetamol, ibuprofen and paracetamol-ibuprofen combination for treatment of febrile children.This was an investigator blind, randomized (...) , comparative, parallel clinical trial conducted in 99 febrile children, 6 months to 12 years of age, allocated to three groups. First group received paracetamol 15 mg/kg, second group received ibuprofen 10 mg/kg and third group received both paracetamol and ibuprofen, all as a single dose by the oral route. Patients were followed-up at intervals of 1, 2, 3 and 4 h post dose by tympanic thermometry.Mean tympanic temperature after 4 h of drug administration was significantly lower in the combination group

2014 Perspectives in clinical research Controlled trial quality: uncertain

8. Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis. Full Text available with Trip Pro

Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis. The cardiovascular safety of celecoxib, as compared with nonselective nonsteroidal antiinflammatory drugs (NSAIDs), remains uncertain.Patients who required NSAIDs for osteoarthritis or rheumatoid arthritis and were at increased cardiovascular risk were randomly assigned to receive celecoxib, ibuprofen, or naproxen. The goal of the trial was to assess the noninferiority of celecoxib with regard to the primary composite (...) group (852±103 mg), or the ibuprofen group (2045±246 mg) for a mean treatment duration of 20.3±16.0 months and a mean follow-up period of 34.1±13.4 months. During the trial, 68.8% of the patients stopped taking the study drug, and 27.4% of the patients discontinued follow-up. In the intention-to-treat analyses, a primary outcome event occurred in 188 patients in the celecoxib group (2.3%), 201 patients in the naproxen group (2.5%), and 218 patients in the ibuprofen group (2.7%) (hazard ratio

2016 NEJM Controlled trial quality: predicted high

9. Turmeric (Curcuma longa): Effects of Curcuma longa Extracts Compared With Ibuprofen for Reduction of Pain and Functional Improvement in Patients With Knee Osteoarthritis. (Abstract)

Turmeric (Curcuma longa): Effects of Curcuma longa Extracts Compared With Ibuprofen for Reduction of Pain and Functional Improvement in Patients With Knee Osteoarthritis. 27078813 2017 01 16 2017 01 16 1550-5138 30 3 2016 May-Jun Holistic nursing practice Holist Nurs Pract Turmeric (Curcuma longa): Effects of Curcuma longa Extracts Compared With Ibuprofen for Reduction of Pain and Functional Improvement in Patients With Knee Osteoarthritis. 183-6 10.1097/HNP.0000000000000152 Ross Stephanie (...) Maxine SM College of Nursing and Health Professions, Drexel University, Philadelphia, Pennsylvania. eng Journal Article Randomized Controlled Trial United States Holist Nurs Pract 8702105 0887-9311 0 Analgesics 0 Plant Extracts WK2XYI10QM Ibuprofen N Abdominal Pain Analgesics adverse effects pharmacology therapeutic use Arthralgia drug therapy Curcuma Female Humans Ibuprofen adverse effects therapeutic use Male Middle Aged Osteoarthritis, Knee drug therapy Patient Satisfaction Plant Extracts adverse

2017 Holistic nursing practice Controlled trial quality: uncertain

10. Alternating Acetaminophen and Ibuprofen versus Monotherapies in Improvements of Distress and Reducing Refractory Fever in Febrile Children: A Randomized Controlled Trial. (Abstract)

Alternating Acetaminophen and Ibuprofen versus Monotherapies in Improvements of Distress and Reducing Refractory Fever in Febrile Children: A Randomized Controlled Trial. No evidence can be found in the medical literature about the efficacy of alternating acetaminophen and ibuprofen treatment in children with refractory fever.Our objective was to assess the effect of alternating acetaminophen and ibuprofen therapy on distress and refractory fever compared with acetaminophen or ibuprofen (...) as monotherapy in febrile children.A total of 474 febrile children with axillary temperature ≥38.5 °C and fever history ≤3 days in a tertiary hospital were randomly assigned to receive either (1) alternating acetaminophen and ibuprofen (acetaminophen 10 mg/kg per dose with shortest interval of 4 h and ibuprofen 10 mg/kg per dose with shortest interval of 6 h and the shortest interval between acetaminophen and ibuprofen ≥2 h; n = 158), (2) acetaminophen monotherapy (10 mg/kg per dose with shortest interval

2017 Paediatric Drugs Controlled trial quality: predicted high

11. Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen

Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen Prescrire IN ENGLISH - Spotlight ''Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen'', 1 January 2016 {1} {1} {1} | | > > > Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |  (...)  |   |   |   |   |   |   |  Spotlight Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen When pain medication is required, paracetamol (alias acetaminophen) is the reference drug. Among the nonsteroidal anti-inflammatories (NSAIDs), naproxen or ibuprofen (not exceeding 1200 mg a day) are the drugs that carry the least exposure to cardiac disorders. When pain medication is needed

2016 Prescrire

12. Comparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial (Abstract)

Comparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial Nonsteroidal anti-inflammatory drugs (NSAIDs) are used extensively for the management of acute pain, with ibuprofen being one of the most frequently used oral analgesics in the emergency department (ED). We compare the analgesic efficacy of oral ibuprofen at 3 different doses for adult ED patients with acute pain.This was a randomized, double-blind trial (...) comparing analgesic efficacy of 3 doses of oral ibuprofen (400, 600, and 800 mg) in adult ED patients with acute painful conditions. Primary outcome included difference in pain scores between the 3 groups at 60 minutes.We enrolled 225 subjects (75 per group). The difference in mean pain scores at 60 minutes between the 400- and 600-mg groups was -0.14 (95% confidence interval [CI] -0.67 to 0.39); between the 400- and 800-mg groups, 0.14 (95% CI -0.65 to 0.37); and between the 600- and 800-mg groups

2019 EvidenceUpdates

13. Should Ibuprofen be Used for COVID-19?

Should Ibuprofen be Used for COVID-19? MOH-ACE COVID-19 RAPID REVIEW 21 March 2020 Page 1 of 2 Clinical evidence Recommendations from professional bodies Background Should ibuprofen be used for COVID-19? This write-up summarises a rapid evidence review of NSAIDs, particularly ibuprofen, to manage symptoms of patients with COVID-19. The information may be revised as new evidence emerges. A news article titled “COVID-19: ibuprofen should not be used for managing symptoms, say doctors (...) and scientists” was published in BMJ on 17 Mar 2020. 1 It claims that anti-inflammatory drugs (eg. ibuprofen, cortisone) could aggravate infection in patients with suspected COVID-19 and paracetamol should be used in these patients; however different views were expressed. No clinical trials were identified assessing the safety of nonsteroidal anti-inflammatory drugs (NSAIDs) in managing symptoms of COVID-19. Instead, there are studies on the potential mechanisms of inflammatory responses and some proposes

2020 Appropriate Care Guides, Agency for Care Effectiveness (Singapore)

14. Revisiting established medicines: an overview of systematic reviews about ibuprofen and paracetamol for treating pain in children. Full Text available with Trip Pro

Revisiting established medicines: an overview of systematic reviews about ibuprofen and paracetamol for treating pain in children. We explored how systematic reviews evaluated paracetamol and ibuprofen for treating pain in children, as these two nonopioid analgesics are well-established medicines included in most national essential medicines lists.We carried out an overview of systematic reviews (SRs) of randomized controlled trials (RCTs) of interventions (PROSPERO registration: 42016045367 (...) ). We searched MEDLINE, EMBASE, Cochrane Database of Systematic Reviews (CDSR) and Database of Reviews of Effects (DARE) up to August 23, 2017. We used AMSTAR checklist to analyze methodological quality of included SRs.We found 17 SRs with 72 unique RCTs; the majority of those trials included under 100 children. Positive conclusive evidence was found in only one SR, regarding safety of paracetamol. Conclusions of other SRs for efficacy and safety of ibuprofen and paracetamol were inconclusive

2019 European Journal of Pain

15. Ibuprofen, Acetaminophen and Dipyrone to Fever Control in Children

Ibuprofen, Acetaminophen and Dipyrone to Fever Control in Children Ibuprofen, Acetaminophen and Dipyrone to Fever Control in Children - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Ibuprofen, Acetaminophen (...) Farmaceutica Ltd. Study Details Study Description Go to Brief Summary: The purpose of this study was to compare the efficacy and tolerability of acetaminophen, dipyrone and ibuprofen to fever control in children. For the efficacy asses were compared: the time to start the action; the action duration; the difference between the basal temperature and the lower temperature in the study period. For the tolerability asses all adverse events were recorded, as well as your intensity and the relation

2011 Clinical Trials

16. Ibuprofen plus paracetamol versus ibuprofen in acute low back pain: a randomized open label multicenter clinical study. (Abstract)

Ibuprofen plus paracetamol versus ibuprofen in acute low back pain: a randomized open label multicenter clinical study. to estimate whether combination of ibuprofen and paracetamol is more effective than ibuprofen in monotherapy, in the treatment of acute low back pain.80 adult patients with acute low back pain were randomized into two subgroups. In the first subgroup, 40 patients were treated with ibuprofen 400mg three times a day (TID), whilst patients in the second subgroup (n=40) were (...) treated with a fixed-dose combination tablet of ibuprofen 200mg plus paracetamol 325mg TID, for three consecutive days. Patients were followed for another 7 days. Efficacy and tolerability of both treatment options was assessed.A statistically significant decrease in pain intensity, assessed using a visual analogue scale (p<0.001), as well as the 5-point Likert scale, was noticed in both subgroups of patients. However, intensity of pain on Day 4 was significantly lower in patients treated

2016 Acta reumatologica portuguesa Controlled trial quality: uncertain

17. Efficacy and safety of ibuprofen and acetaminophen in children and adults: a meta-analysis and qualitative review

Efficacy and safety of ibuprofen and acetaminophen in children and adults: a meta-analysis and qualitative review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2010 DARE.

18. Ibuprofen for the prevention of patent ductus arteriosus in preterm and/or low birth weight infants. (Abstract)

Ibuprofen for the prevention of patent ductus arteriosus in preterm and/or low birth weight infants. Patent ductus arteriosus (PDA) complicates the clinical course of preterm infants and increases the risk of adverse outcomes. Indomethacin has been the standard treatment to close a PDA but is associated with renal, gastrointestinal, and cerebral side effects. Ibuprofen has less effect on blood flow velocity to important organs.Primary objectivesTo determine the effectiveness and safety (...) of ibuprofen compared to placebo/no intervention, or other cyclo-oxygenase inhibitor drugs in the prevention of PDA in preterm infants.We used the standard search strategy of Cochrane Neonatal to search the Cochrane Central Register of Controlled Trials (CENTRAL; 2018, Issue 10), MEDLINE via PubMed (1966 to 17 October 2018), Embase (1980 to 17 October 2018), and CINAHL; 1982 to 17 October 2018). We searched clinical trials databases, conference proceedings, and the reference lists of retrieved articles

2019 Cochrane

19. Altitude Sickness Prevention with Ibuprofen Relative to Acetazolamide (Abstract)

Altitude Sickness Prevention with Ibuprofen Relative to Acetazolamide Acute mountain sickness is a common occurrence for travel to high altitudes. Although previous studies of ibuprofen have shown efficacy for the prevention of acute mountain sickness, recommendations have been limited, as ibuprofen has not been compared directly with acetazolamide until this study.Before their ascent to 3810 m on White Mountain in California, adult volunteers were randomized to ibuprofen (600 mg, 3 times daily (...) , started 4 hours before the ascent), or to acetazolamide (125 mg, twice daily, started the night before the ascent). The main outcome measure was acute mountain sickness incidence, using the Lake Louise Questionnaire (LLQ), with a score of >3 with headache. Sleep quality and headache severity were measured with the Groningen Sleep Quality Survey (GSQS). This trial was registered at ClinicalTrials.gov: NCT03154645 RESULTS: Ninety-two participants completed the study: 45 (49%) on ibuprofen and 47 (51

2019 EvidenceUpdates

20. Systematic review of the effectiveness of combination oral ibuprofen and paracetamol for pain management

Systematic review of the effectiveness of combination oral ibuprofen and paracetamol for pain management Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files

2019 PROSPERO