Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4)
Latest & greatest articles for hypothermia
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on hypothermia or other clinical topics then use Trip today.
This page lists the very latest high quality evidence on hypothermia and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.
What is Trip?
Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.
Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.
As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.
For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via firstname.lastname@example.org
Active cutaneous warming systems to prevent intraoperative hypothermia: a systematic review Active cutaneous warming systems to prevent intraoperative hypothermia: a systematic review Active cutaneous warming systems to prevent intraoperative hypothermia: a systematic review de Brito Poveda V, Martinez EZ, Galvao CM CRD summary This review concluded that, compared with forced-air warming, circulating water garments were more effective in maintaining the temperature of patients during surgery (...) ; carbon-fibre systems were as effective as forced air. The trials were generally small and of low quality and there were flaws in the search and review processes. The conclusions should be treated with caution. Authors' objectives To assess the effectiveness of different active cutaneous warming systems to prevent hypothermia during surgery. Searching MEDLINE, CINAHL, Cochrane Central Register of Controlled Trials (CENTRAL), and EMBASE were searched for articles from 2000 to August 2010. Search terms
Therapeutic hypothermia and prevention of acute kidney injury: a meta-analysis of randomized controlled trials Therapeutic hypothermia and prevention of acute kidney injury: a meta-analysis of randomized controlled trials Therapeutic hypothermia and prevention of acute kidney injury: a meta-analysis of randomized controlled trials Susantitaphong P, Alfayez M, Cohen-Bucay A, Balk EM, Jaber BL CRD summary The review found that in trials of therapeutic hypothermia that assessed kidney outcomes (...) , therapeutic hypothermia did not appear to reduce acute kidney injury or need for dialysis and was associated with lower mortality. These conclusions should be regarded with some caution due to the poor quality of included trials and the lack of trials specifically designed to measure kidney outcomes. Authors' objectives To assess the effect of therapeutic hypothermia on development of acute kidney injury and mortality. Searching MEDLINE (to February 2011) and ClinicalTrials.gov were searched
Hypothermia for newborns with hypoxic ischemic encephalopathy Hypothermia for newborns with hypoxic ischemic encephalopathy | Position statements and practice points | Hypothermia for newborns with hypoxic ischemic encephalopathy | Canadian Paediatric Society Protecting and promoting the health and well-being of children and youth CPS Member Login | Who We Are What We Do Get Involved Education/CPD Publications Careers > Share PRACTICE POINT Hypothermia for newborns with hypoxic ischemic (...) hypothermia to a rectal temperature of 34±0.5°C initiated as soon as possible within the first 6 h of life decreases mortality and severe long-term neurodevelopmental disabilities in infants with moderate HIE who are ≥36 weeks’ gestational age. There are minimal side effects, and the incidence of disability in survivors is not increased. Infants with severe encephalopathy are less likely to benefit from treatment. Cooling may be achieved by either total body or selective head cooling. As cooling is now
Childhood outcomes after hypothermia for neonatal encephalopathy. 22646631 2012 05 31 2012 06 05 2016 12 15 1533-4406 366 22 2012 May 31 The New England journal of medicine N. Engl. J. Med. Childhood outcomes after hypothermia for neonatal encephalopathy. 2085-92 10.1056/NEJMoa1112066 We previously reported early results of a randomized trial of whole-body hypothermia for neonatal hypoxic-ischemic encephalopathy showing a significant reduction in the rate of death or moderate or severe (...) disability at 18 to 22 months of age. Long-term outcomes are now available. In the original trial, we assigned infants with moderate or severe encephalopathy to usual care (the control group) or whole-body cooling to an esophageal temperature of 33.5°C for 72 hours, followed by slow rewarming (the hypothermia group). We evaluated cognitive, attention and executive, and visuospatial function; neurologic outcomes; and physical and psychosocial health among participants at 6 to 7 years of age. The primary
Systemic hypothermia to prevent radiocontrast nephropathy (from the COOL-RCN Randomized Trial) 21676368 2011 08 15 2011 10 24 2013 11 21 1879-1913 108 5 2011 Sep 01 The American journal of cardiology Am. J. Cardiol. Systemic hypothermia to prevent radiocontrast nephropathy (from the COOL-RCN Randomized Trial). 741-6 10.1016/j.amjcard.2011.04.026 Radiocontrast nephropathy (RCN) develops in a substantial proportion of patients with chronic kidney disease (CKD) after invasive cardiology procedures (...) and is strongly associated with subsequent mortality and adverse outcomes. We sought to determine whether systemic hypothermia is effective in preventing RCN in patients with CKD. Patients at risk for RCN (baseline estimated creatinine clearance 20 to 50 ml/min) undergoing cardiac catheterization with iodinated contrast ≥50 ml were randomized 1:1 to hydration (control arm) versus hydration plus establishment of systemic hypothermia (33°C to 34°C) before first contrast injection and for 3 hours after
Hypothermia for neuroprotection after cardiac arrest: systematic review and individual patient data meta-analysis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?
[Therapeutic hypothermia in patients who underwent cardiac arrest resuscitation] Hipotermia terapeutica en pacientes resucitados de un paro cardiaco [Therapeutic hypothermia in patients who underwent cardiac arrest resuscitation] Hipotermia terapeutica en pacientes resucitados de un paro cardiaco [Therapeutic hypothermia in patients who underwent cardiac arrest resuscitation] Pichon Riviere A, Augustovski F, Garcia Marti S, Glujovsky D, Lopez A, Rey-Ares L, Bardach A, Regueiro A, Alcaraz (...) A, Valanzasca P, Elorriaga N, Romano M, Rojas J Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Pichon Riviere A, Augustovski F, Garcia Marti S, Glujovsky D, Lopez A, Rey-Ares L, Bardach A, Regueiro A, Alcaraz A, Valanzasca P, Elorriaga N, Romano M, Rojas J. Hipotermia terapeutica en pacientes resucitados de un paro cardiaco. [Therapeutic hypothermia
[Therapeutic hypothermia in patients with stroke or brain trauma] Hipotermia terapeutica en pacientes con accidente cerebrovascular o traumatismo cerebral [Therapeutic hypothermia in patients with stroke or brain trauma] Hipotermia terapeutica en pacientes con accidente cerebrovascular o traumatismo cerebral [Therapeutic hypothermia in patients with stroke or brain trauma] Pichon Riviere A, Augustovski F, Garcia Marti S, Glujovsky D, Lopez A, Rey-Ares L, Bardach A, Regueiro A, Alcaraz (...) . [Therapeutic hypothermia in patients with stroke or brain trauma] Buenos Aires: Institute for Clinical Effectiveness and Health Policy (IECS). Informe de Respuesta Rapida No 230. 2011 Authors' objectives To assess the available evidence on the efficacy, safety and issues related with coverage of therapeutic hypothermia in patients with stroke or brain trauma. Authors' conclusions Based on the results of the analyzed studies, there is no evidence to support the use of therapeutic hypothermia in patients
Very early hypothermia induction in patients with severe brain injury (the National Acute Brain Injury Study: Hypothermia II): a randomised trial 21169065 2011 01 24 2011 03 01 2016 12 15 1474-4465 10 2 2011 Feb The Lancet. Neurology Lancet Neurol Very early hypothermia induction in patients with severe brain injury (the National Acute Brain Injury Study: Hypothermia II): a randomised trial. 131-9 10.1016/S1474-4422(10)70300-8 The inconsistent effect of hypothermia treatment on severe brain (...) injury in previous trials might be because hypothermia was induced too late after injury. We aimed to assess whether very early induction of hypothermia improves outcome in patients with severe brain injury. The National Acute Brain Injury Study: Hypothermia II (NABIS: H II) was a randomised, multicentre clinical trial of patients with severe brain injury who were enrolled within 2·5 h of injury at six sites in the USA and Canada. Patients with non-penetrating brain injury who were 16-45 years old
Video-EEG monitoring in newborns with hypoxic-ischemic encephalopathy treated with hypothermia 21300971 2011 02 08 2011 03 23 2016 10 19 1526-632X 76 6 2011 Feb 08 Neurology Neurology Video-EEG monitoring in newborns with hypoxic-ischemic encephalopathy treated with hypothermia. 556-62 10.1212/WNL.0b013e31820af91a Therapeutic hypothermia (TH) is becoming standard of care in newborns with hypoxic-ischemic encephalopathy (HIE). The prognostic value of the EEG and the incidence of seizures during (...) TH are uncertain. To describe evolution of EEG background and incidence of seizures during TH, and to identify EEG patterns predictive for MRI brain injury. A total of 41 newborns with HIE underwent TH. Continuous video-EEG was performed during hypothermia and rewarming. EEG background and seizures were reported in a standardized manner. Newborns underwent MRI after rewarming. Sensitivity and specificity of EEG background for moderate to severe MRI brain injury was assessed at 6-hour intervals
Hypothermia for Neuroprotection After Cardiac Arrest Hypothermia for Neuroprotection After Cardiac Arrest – TheNNTTheNNT Mild Therapeutic Hypothermia for Neuroprotection Following Cardiopulmonary Resuscitation (CPR) 6 for mortality In summary, for patients treated with mild hypothermia after CPR: Benefits in NNT 84% saw no benefit 16% were helped by having a neurologically-intact survival 1 in 6 were helped (neurologically-intact life saved) Harms in NNT 0% were harmed None were harmed View (...) As: NNT % Source: Efficacy Endpoints: Neurologic recovery (best outcome while in hospital, as measured by cerebral performance categories), survival to hospital discharge Harm Endpoints: Bleeding, pneumonia, sepsis, pulmonary edema, cardiac dysrhythmias Narrative: After the return of spontaneous circulation following cardiac arrest, neurologic injury may occur in the process of reperfusion. Past investigations have suggested that the induction of hypothermia in initially comatose survivors can help
Therapeutic hypothermia following cardiac arrest (IPG386) Therapeutic hypothermia following cardiac arrest | Guidance and guidelines | NICE Therapeutic hypothermia following cardiac arrest Interventional procedures guidance [IPG386] Published date: March 2011 Share Save Guidance and for this guidance. Your responsibility This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, healthcare professionals
Therapeutic hypothermia initiated in the pre-hospital setting: a meta-analysis Therapeutic hypothermia initiated in the pre-hospital setting: a meta-analysis Therapeutic hypothermia initiated in the pre-hospital setting: a meta-analysis Cullen D, Augenstine D, Kaper L, Tinkham S, Utz D CRD summary The review concluded that induced therapeutic hypothermia in the pre-hospital setting was safe and effective after cardiac arrest. Potential for bias and a limited evidence base of unknown quality (...) mean that the authors' conclusions cannot be considered reliable. Authors' objectives To examine the feasibility and safety of pre-hospital hypothermia after cardiac arrest. Searching CINAHL, MEDLINE, EMBASE, The Cochrane Library and Web of Science were searched from 2007 to 2010 for relevant studies published in English; search terms were not reported. Reference lists of retrieved studies were searched. Study selection Randomised controlled trials (RCTs) of patients 15 years or older who received
Systemic hypothermia after neonatal encephalopathy: outcomes of neo.nEURO.network RCT 20855387 2010 10 05 2010 10 27 2013 11 21 1098-4275 126 4 2010 Oct Pediatrics Pediatrics Systemic hypothermia after neonatal encephalopathy: outcomes of neo.nEURO.network RCT. e771-8 10.1542/peds.2009-2441 Mild hypothermia after perinatal hypoxic-ischemic encephalopathy (HIE) reduces neurologic sequelae without significant adverse effects, but studies are needed to determine the most-efficacious methods (...) . In the neo.nEURO.network trial, term neonates with clinical and electrophysiological evidence of HIE were assigned randomly to either a control group, with a rectal temperature of 37°C (range: 36.5-37.5°C), or a hypothermia group, cooled and maintained at a rectal temperature of 33.5°C (range: 33-34°C) with a cooling blanket for 72 hours, followed by slow rewarming. All infants received morphine (0.1 mg/kg) every 4 hours or an equivalent dose of fentanyl. Neurodevelopmental outcomes were assessed at the age of 18
Selective head cooling with mild systemic hypothermia after neonatal hypoxic-ischemic encephalopathy: a multicenter randomized controlled trial in China 20488453 2010 08 23 2010 09 23 2010 08 23 1097-6833 157 3 2010 Sep The Journal of pediatrics J. Pediatr. Selective head cooling with mild systemic hypothermia after neonatal hypoxic-ischemic encephalopathy: a multicenter randomized controlled trial in China. 367-72, 372.e1-3 10.1016/j.jpeds.2010.03.030 To investigate the efficacy and safety (...) of selective head cooling with mild systemic hypothermia in hypoxic-ischemic encephalopathy (HIE) in newborn infants. Infants with HIE were randomly assigned to the selective head cooling or control group. Selective head cooling was initiated within 6 hours after birth to a nasopharyngeal temperature of 34 degrees+/-0.2 degrees C and rectal temperature of 34.5 degrees to 35.0 degrees C for 72 hours. Rectal temperature was maintained at 36.0 degrees to 37.5 degrees C in the control group. Neurodevelopmental