Latest & greatest articles for hypothermia

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Top results for hypothermia

62. Effects of hypothermia for perinatal asphyxia on childhood outcomes.

Effects of hypothermia for perinatal asphyxia on childhood outcomes. BACKGROUND: In the Total Body Hypothermia for Neonatal Encephalopathy Trial (TOBY), newborns with asphyxial encephalopathy who received hypothermic therapy had improved neurologic outcomes at 18 months of age, but it is uncertain whether such therapy results in longer-term neurocognitive benefits. METHODS: We randomly assigned 325 newborns with asphyxial encephalopathy who were born at a gestational age of 36 weeks or more (...) to receive standard care alone (control) or standard care with hypothermia to a rectal temperature of 33 to 34°C for 72 hours within 6 hours after birth. We evaluated the neurocognitive function of these children at 6 to 7 years of age. The primary outcome of this analysis was the frequency of survival with an IQ score of 85 or higher. RESULTS: A total of 75 of 145 children (52%) in the hypothermia group versus 52 of 132 (39%) in the control group survived with an IQ score of 85 or more (relative risk

NEJM2014

63. Hypothermia for Neonatal Hypoxic Ischemic Encephalopathy: An Updated Systematic Review and Meta-analysis

Hypothermia for Neonatal Hypoxic Ischemic Encephalopathy: An Updated Systematic Review and Meta-analysis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2014

64. Induced Hypothermia in Severe Bacterial Meningitis: A Randomized Clinical Trial

Induced Hypothermia in Severe Bacterial Meningitis: A Randomized Clinical Trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2014

65. Induced Hypothermia in Severe Bacterial Meningitis: A Randomized Clinical Trial

Induced Hypothermia in Severe Bacterial Meningitis: A Randomized Clinical Trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2014

66. Safety and efficacy of therapeutic hypothermia for acute ischemic stroke. Systematic review and Meta-analysis

Safety and efficacy of therapeutic hypothermia for acute ischemic stroke. Systematic review and Meta-analysis Seguridad y eficacia de la terapia hipotérmica en el ictus isquémico agudo. Revisión sistemática y metaanálisis [Safety and efficacy of therapeutic hypothermia for acute ischemic stroke. Systematic review and Meta-analysis] Seguridad y eficacia de la terapia hipotérmica en el ictus isquémico agudo. Revisión sistemática y metaanálisis [Safety and efficacy of therapeutic hypothermia (...) of therapeutic hypothermia for acute ischemic stroke. Systematic review and Meta-analysis] Seville: Andalusian Agency for Health Technology Assessment (AETSA). AETSA 2013/5-2. 2013 Authors' conclusions Therapeutic Hypothermia can be achieved by different devices. Methods involve surface cooling (noninvasive), and internal cooling (non-invasive and invasive). According to the type of methods used, the therapeutic hypothermia presents different complexity and risks for patients. The neuroprotective effect

Health Technology Assessment (HTA) Database.2014

67. Hypothermia and Early Neonatal Mortality in Preterm Infants

Hypothermia and Early Neonatal Mortality in Preterm Infants 24210925 2014 01 27 2014 03 25 2014 01 27 1097-6833 164 2 2014 Feb The Journal of pediatrics J. Pediatr. Hypothermia and early neonatal mortality in preterm infants. 271-5.e1 10.1016/j.jpeds.2013.09.049 S0022-3476(13)01220-1 To evaluate intervention practices associated with hypothermia at both 5 minutes after birth and at neonatal intensive care unit (NICU) admission and to determine whether hypothermia at NICU admission is associated (...) with early neonatal death in preterm infants. This prospective cohort included 1764 inborn neonates of 22-33 weeks without malformations admitted to 9 university NICUs from August 2010 through April 2012. All centers followed neonatal International Liaison Committee on Resuscitation recommendations for the stabilization and resuscitation in the delivery room (DR). Variables associated with hypothermia (axillary temperature <36.0 °C) 5 minutes after birth and at NICU admission, as well as those associated

EvidenceUpdates2014

68. Normothermia versus therapeutic hypothermia for adult patients after cardiac arrest: clinical evidence

Normothermia versus therapeutic hypothermia for adult patients after cardiac arrest: clinical evidence Normothermia versus therapeutic hypothermia for adult patients after cardiac arrest: clinical evidence Normothermia versus therapeutic hypothermia for adult patients after cardiac arrest: clinical evidence CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made (...) for the HTA database. Citation CADTH. Normothermia versus therapeutic hypothermia for adult patients after cardiac arrest: clinical evidence. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). Rapid Response. 2014 Authors' conclusions Six systematic reviews and one randomized controlled trial were identified regarding the comparative neurological benefits and harms of maintaining normothermia versus induction of therapeutic hypothermia in adult patients following cardiac arrest. Final

Health Technology Assessment (HTA) Database.2014

69. Randomised controlled trial: Plastics bags reduce hypothermia in newly born infants in the developing world

Randomised controlled trial: Plastics bags reduce hypothermia in newly born infants in the developing world Plastics bags reduce hypothermia in newly born infants in the developing world | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search (...) for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Plastics bags reduce hypothermia in newly born infants in the developing world Article Text Therapeutics Randomised controlled trial Plastics bags reduce hypothermia in newly born infants in the developing world Colm P F O'Donnell Statistics from Altmetric.com No Altmetric data available for this article. Commentary

Evidence-Based Medicine (Requires free registration)2014

70. Effects of hypothermia for perinatal asphyxia on childhood outcomes.

Effects of hypothermia for perinatal asphyxia on childhood outcomes. 25006720 2014 07 10 2014 07 22 2016 11 22 1533-4406 371 2 2014 Jul 10 The New England journal of medicine N. Engl. J. Med. Effects of hypothermia for perinatal asphyxia on childhood outcomes. 140-9 10.1056/NEJMoa1315788 In the Total Body Hypothermia for Neonatal Encephalopathy Trial (TOBY), newborns with asphyxial encephalopathy who received hypothermic therapy had improved neurologic outcomes at 18 months of age (...) , but it is uncertain whether such therapy results in longer-term neurocognitive benefits. We randomly assigned 325 newborns with asphyxial encephalopathy who were born at a gestational age of 36 weeks or more to receive standard care alone (control) or standard care with hypothermia to a rectal temperature of 33 to 34°C for 72 hours within 6 hours after birth. We evaluated the neurocognitive function of these children at 6 to 7 years of age. The primary outcome of this analysis was the frequency of survival

NEJM2014

71. Effect of prehospital induction of mild hypothermia on survival and neurological status among adults with cardiac arrest: a randomized clinical trial.

Effect of prehospital induction of mild hypothermia on survival and neurological status among adults with cardiac arrest: a randomized clinical trial. 24240712 2014 01 01 2014 01 13 2016 10 17 1538-3598 311 1 2014 Jan 01 JAMA JAMA Effect of prehospital induction of mild hypothermia on survival and neurological status among adults with cardiac arrest: a randomized clinical trial. 45-52 10.1001/jama.2013.282173 Hospital cooling improves outcome after cardiac arrest, but prehospital cooling (...) prevention & control Emergency Medical Services Female Humans Hypothermia, Induced Male Middle Aged Out-of-Hospital Cardiac Arrest physiopathology therapy Sodium Chloride administration & dosage Survival Analysis Ventricular Fibrillation complications therapy 2013 11 19 6 0 2013 11 19 6 0 2014 1 15 6 0 ppublish 24240712 1778673 10.1001/jama.2013.282173

JAMA2014

72. Effect of prehospital induction of mild hypothermia on survival and neurological status among adults with cardiac arrest: a randomized clinical trial.

Effect of prehospital induction of mild hypothermia on survival and neurological status among adults with cardiac arrest: a randomized clinical trial. IMPORTANCE: Hospital cooling improves outcome after cardiac arrest, but prehospital cooling immediately after return of spontaneous circulation may result in better outcomes. OBJECTIVE: To determine whether prehospital cooling improves outcomes after resuscitation from cardiac arrest in patients with ventricular fibrillation (VF) and without VF

JAMA2014

73. Paediatric Traumatic Brain Injury Consortium. Comparison of hypothermia and normothermia after severe traumatic brain injury in children (Cool Kids): a phase 3, randomised controlled trial

Paediatric Traumatic Brain Injury Consortium. Comparison of hypothermia and normothermia after severe traumatic brain injury in children (Cool Kids): a phase 3, randomised controlled trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2013

74. Therapeutic hypothermia and the risk of infection: a systematic review and meta-analysis

Therapeutic hypothermia and the risk of infection: a systematic review and meta-analysis Therapeutic hypothermia and the risk of infection: a systematic review and meta-analysis Therapeutic hypothermia and the risk of infection: a systematic review and meta-analysis Geurts M, Macleod MR, Kollmar R, Kremer PH, van der Worp HB CRD summary The authors concluded that cooling increased the risk of pneumonia and sepsis but found no convincing evidence of an increased overall rate of infections (...) . This review appeared generally well conducted and despite the limitations found in the evidence the conclusions are probably reliable. Authors' objectives To evaluate whether therapeutic hypothermia in adults is associated with an increased risk of infections. Searching PUBMED, EMBASE and Cochrane Central Register of Controlled Trials (CENTRAL) were searched up to October 2012 for relevant studies in English, Dutch or German. Reference lists of included studies and Cochrane reviews were consulted. Search

DARE.2013

75. Induced Hypothermia in Severe Bacterial Meningitis: A Randomized Clinical Trial.

Induced Hypothermia in Severe Bacterial Meningitis: A Randomized Clinical Trial. IMPORTANCE: Despite advances in care, mortality and morbidity remain high in adults with acute bacterial meningitis, particularly when due to Streptococcus pneumoniae. Induced hypothermia is beneficial in other conditions with global cerebral hypoxia. OBJECTIVE: To test the hypothesis that induced hypothermia improves outcome in patients with severe bacterial meningitis. DESIGN, SETTING, AND PATIENTS: An open-label (...) , multicenter, randomized clinical trial in 49 intensive care units in France, February 2009-November 2011. In total, 130 patients were assessed for eligibility and 98 comatose adults (Glasgow Coma Scale [GCS] score of ≤8 for <12 hours) with community-acquired bacterial meningitis were randomized. INTERVENTIONS: Hypothermia group received a loading dose of 4°C cold saline and were cooled to 32°C to 34°C for 48 hours. The rewarming phase was passive. Controls received standard care. MAIN OUTCOMES

JAMA2013

76. Safety profile and outcome of mild therapeutic hypothermia in patients following cardiac arrest: systematic review and meta-analysis

Safety profile and outcome of mild therapeutic hypothermia in patients following cardiac arrest: systematic review and meta-analysis Safety profile and outcome of mild therapeutic hypothermia in patients following cardiac arrest: systematic review and meta-analysis Safety profile and outcome of mild therapeutic hypothermia in patients following cardiac arrest: systematic review and meta-analysis Xiao G, Guo Q, Shu M, Xie X, Deng J, Zhu Y, Wan C CRD summary The authors concluded that mild (...) therapeutic hypothermia was generally safe, for comatose patients, following a cardiac arrest, and it could improve their short- and long-term survival. Given the heterogeneity across studies, for mortality, and the small numbers of studies reporting adverse events, the authors' suggestion to interpret the findings cautiously should be heeded; the findings may not be reliable. Authors' objectives To assess the safety and efficacy of mild therapeutic hypothermia, for patients following a cardiac arrest

DARE.2013

77. Comparison of hypothermia and normothermia after severe traumatic brain injury in children (Cool Kids): a phase 3, randomised controlled trial

Comparison of hypothermia and normothermia after severe traumatic brain injury in children (Cool Kids): a phase 3, randomised controlled trial 23664370 2013 05 20 2013 07 22 2016 06 29 1474-4465 12 6 2013 Jun The Lancet. Neurology Lancet Neurol Comparison of hypothermia and normothermia after severe traumatic brain injury in children (Cool Kids): a phase 3, randomised controlled trial. 546-53 10.1016/S1474-4422(13)70077-2 S1474-4422(13)70077-2 On the basis of mixed results from previous trials (...) , we assessed whether therapeutic hypothermia for 48-72 h with slow rewarming improved mortality in children after brain injury. In this phase 3, multicenter, multinational, randomised controlled trial, we included patients with severe traumatic brain injury who were younger than 18 years and could be enrolled within 6 h of injury. We used a computer-generated randomisation sequence to randomly allocate patients (1:1; stratified by site and age [<6 years, 6-15 years, 16-17 years]) to either

EvidenceUpdates2013

78. Randomized Trial of Plastic Bags to Prevent Term Neonatal Hypothermia in a Resource-Poor Setting

Randomized Trial of Plastic Bags to Prevent Term Neonatal Hypothermia in a Resource-Poor Setting 23979082 2013 09 03 2013 10 30 2017 02 20 1098-4275 132 3 2013 Sep Pediatrics Pediatrics Randomized trial of plastic bags to prevent term neonatal hypothermia in a resource-poor setting. e656-61 10.1542/peds.2013-0172 Term infants in resource-poor settings frequently develop hypothermia during the first hours after birth. Plastic bags or wraps are a low-cost intervention for the prevention (...) of hypothermia in preterm and low birth weight infants that may also be effective in term infants. Our objective was to test the hypothesis that placement of term neonates in plastic bags at birth reduces hypothermia at 1 hour after birth in a resource-poor hospital. This parallel-group randomized controlled trial was conducted at University Teaching Hospital, the tertiary referral center in Zambia. Inborn neonates with both a gestational age ≥37 weeks and a birth weight ≥2500 g were randomized 1:1 to either

EvidenceUpdates2013 Full Text: Link to full Text with Trip Pro

79. Therapeutic hypothermia for cardiac arrest of asphyxial origin

Therapeutic hypothermia for cardiac arrest of asphyxial origin BestBets: Therapeutic hypothermia for cardiac arrest of asphyxial origin Therapeutic hypothermia for cardiac arrest of asphyxial origin Report By: Eric Mercier - Emergency medicine PGY-3 Search checked by Gareth Roberts - Central Manchester University Hospitals NHS Foundation Trust, UK Institution: Laval University, Quebec, Canada Date Submitted: 17th July 2012 Date Completed: 25th July 2013 Last Modified: 25th July 2013 Status (...) : Green (complete) Three Part Question In [comatose adults patients presenting to the emergency department following asphyxia] does [therapeutic hypothermia] improve [neurologic outcome]? Clinical Scenario A 34-year-old woman is discovered hanging from a noose around her neck. When a family member discovers her, she is in respiratory arrest and comatose. The paramedics provide artificial ventilation. After several minutes, the patient\'s breathing returns but she remains unconscious. On arrival

BestBETS2013

80. Plastic Bags for Prevention of Hypothermia in Preterm and Low Birth Weight Infants

Plastic Bags for Prevention of Hypothermia in Preterm and Low Birth Weight Infants 23733796 2013 07 03 2013 09 03 2017 02 20 1098-4275 132 1 2013 Jul Pediatrics Pediatrics Plastic bags for prevention of hypothermia in preterm and low birth weight infants. e128-34 10.1542/peds.2012-2030 Hypothermia contributes to neonatal mortality and morbidity, especially in preterm and low birth weight infants in developing countries. Plastic bags covering the trunk and extremities of very low birth weight (...) infants reduces hypothermia. This technique has not been studied in larger infants or in many resource-limited settings. The objective was to determine if placing preterm and low birth weight infants inside a plastic bag at birth maintains normothermia. Infants at 26 to 36 weeks' gestational age and/or with a birth weight of 1000 to 2500 g born at the University Teaching Hospital in Lusaka, Zambia, were randomized by using a 1:1 allocation and parallel design to standard thermoregulation (blanket

EvidenceUpdates2013 Full Text: Link to full Text with Trip Pro