Latest & greatest articles for hypertension

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Top results for hypertension

1121. Does drug treatment improve survival: reconciling the trials in mild-to-moderate hypertension

Does drug treatment improve survival: reconciling the trials in mild-to-moderate hypertension Does drug treatment improve survival: reconciling the trials in mild-to-moderate hypertension Does drug treatment improve survival: reconciling the trials in mild-to-moderate hypertension Hoes A W, Grobbee D E, Lubsen J Authors' objectives To evaluate whether drug treatment for mild-to-moderate hypertension in middle-aged patients improves survival. Searching The authors state that a thorough (...) literature search was carried out but do not provide details. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs) were included. Specific interventions included in the review Anti-hypertensive drug treatment (hydrochlorothiazide; hydralazine; chlorthalidone; chlorothiazide; bendrofluazide; propranolol). The control group received a placebo, no treatment or referred care. Participants included in the review Middle-aged patients with mild-to-moderate

DARE.1995

1122. Delivery of care for hypertension

Delivery of care for hypertension Delivery of care for hypertension Delivery of care for hypertension McInnes G T, McGhee S M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Hypertension care Type of intervention Secondary (...) of effectiveness data Single study. Link between effectiveness and cost data Costing was not undertaken on the same patient sample as that used in the effectiveness study. Costing was undertaken prospectively. Study sample 831 patients suffering from hypertension in 3 groups (shared care, outpatient care, nurse-practitioner clinic care), each consisting of 277 members. Those with well controlled blood pressure (BP), as determined by their consultant, were matched for age, sex and clinic attendance length (n

NHS Economic Evaluation Database.1995

1123. 'White-coat' hypertension in patients with newly diagnosed hypertension: evaluation of prevalence by ambulatory monitoring and impact on cost of health care

'White-coat' hypertension in patients with newly diagnosed hypertension: evaluation of prevalence by ambulatory monitoring and impact on cost of health care 'White-coat' hypertension in patients with newly diagnosed hypertension: evaluation of prevalence by ambulatory monitoring and impact on cost of health care 'White-coat' hypertension in patients with newly diagnosed hypertension: evaluation of prevalence by ambulatory monitoring and impact on cost of health care Pierdomenico S D, Mezzetti (...) of hypertension to be treated by drugs. Type of intervention Diagnosis. Economic study type Cost-effectiveness analysis (but the effects and costs were not brought together: effectiveness was used only in the calculation of costs). Study population 131 males and 124 females aged between 33 and 65. They all had systolic and diastolic blood pressure higher than 140 Setting A referral centre in Italy. Dates to which data relate No dates for cost and effectiveness data were reported. Source of effectiveness data

NHS Economic Evaluation Database.1995

1124. The cost-effectiveness of a cardiovascular multiple-risk-factor intervention programme in treated hypertensive men

The cost-effectiveness of a cardiovascular multiple-risk-factor intervention programme in treated hypertensive men The cost-effectiveness of a cardiovascular multiple-risk-factor intervention programme in treated hypertensive men The cost-effectiveness of a cardiovascular multiple-risk-factor intervention programme in treated hypertensive men Johannesson M, Agewall S, Hartford M, Hedner T, Fagerberg B Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology A multifactor intervention programme for hypertensive men, ie advice given to individuals, and group meetings based on nutritional advice and behavioural treatment principles, plus drug therapy if necessary. Type of intervention Primary prevention Economic study type Cost

NHS Economic Evaluation Database.1995

1125. The cost effectiveness of hypertension treatment in Sweden

The cost effectiveness of hypertension treatment in Sweden The cost effectiveness of hypertension treatment in Sweden The cost effectiveness of hypertension treatment in Sweden Johannesson M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn (...) to ensure the validity of primary studies Not stated. Methods used to judge relevance and validity, and for extracting data Not stated. Number of primary studies included Not stated. Methods of combining primary studies Not stated. Investigation of differences between primary studies Not stated. Results of the review The risk reduction associated with anti-hypertensive drug treatment was 38% for stroke and 16% for CHD. Measure of benefits used in the economic analysis Life-years gained. Direct costs

NHS Economic Evaluation Database.1995

1126. Effects of regular exercise on blood pressure and left ventricular hypertrophy in African-American men with severe hypertension.

Effects of regular exercise on blood pressure and left ventricular hypertrophy in African-American men with severe hypertension. 7477146 1995 12 01 1995 12 01 2013 11 21 0028-4793 333 22 1995 Nov 30 The New England journal of medicine N. Engl. J. Med. Effects of regular exercise on blood pressure and left ventricular hypertrophy in African-American men with severe hypertension. 1462-7 The prevalence of hypertension and its cardiovascular complications is higher in African Americans than (...) in whites. Interventions to control blood pressure in this population are particularly important. Regular exercise lowers blood pressure in patients with mild-to-moderate hypertension, but its effects in patients with severe hypertension have not been studied. We examined the effects of moderately intense exercise on blood pressure and left ventricular hypertrophy in African-American men with severe hypertension. We randomly assigned 46 men 35 to 76 years of age to exercise plus antihypertensive

NEJM1995

1127. Suppression of alcohol-induced hypertension by dexamethasone.

Suppression of alcohol-induced hypertension by dexamethasone. 7760888 1995 06 29 1995 06 29 2013 11 21 0028-4793 332 26 1995 Jun 29 The New England journal of medicine N. Engl. J. Med. Suppression of alcohol-induced hypertension by dexamethasone. 1733-7 Alcohol consumption is associated with an increased incidence of hypertension and stroke, but the triggering mechanisms are unclear. In animals, alcohol causes activation of the sympathetic nervous system and also stimulates the release (...) Dexamethasone 9015-71-8 Corticotropin-Releasing Hormone Z468598HBV Phentolamine AIM IM N Engl J Med. 1995 Jun 29;332(26):1782-3 7760897 Action Potentials Adult Blood Pressure drug effects Corticotropin-Releasing Hormone secretion Dexamethasone pharmacology Double-Blind Method Ethanol pharmacology Female Hemodynamics drug effects Humans Hypertension chemically induced physiopathology Infusions, Intravenous Male Phentolamine pharmacology Sympathetic Nervous System drug effects 1995 6 29 1995 6 29 0 1 1995 6

NEJM1995

1128. Small, blue collar work site hypertension screening: a cost effectiveness study

Small, blue collar work site hypertension screening: a cost effectiveness study Small, blue collar work site hypertension screening: a cost effectiveness study Small, blue collar work site hypertension screening: a cost effectiveness study Ellis E, Koblin W, Irvine M J, Legare J, Logan A G Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions (...) followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology One-stage versus two-stage screening for hypertension. One-stage screening consists of a single blood pressure measurement and those with a diastolic blood pressure (DBP) of 90-99 mmHg and already on medication or DBP of 100-114 mmHg were advised to contact their physician within one month. Two-stage screening consisted of two screening tests two weeks apart, with those of high DBP

NHS Economic Evaluation Database.1994

1129. Cost-minimisation analysis of initial antihypertensive therapy in patients with mild to moderate essential diastolic hypertension

Cost-minimisation analysis of initial antihypertensive therapy in patients with mild to moderate essential diastolic hypertension Cost-minimisation analysis of initial antihypertensive therapy in patients with mild to moderate essential diastolic hypertension Cost-minimisation analysis of initial antihypertensive therapy in patients with mild to moderate essential diastolic hypertension Hilleman D E, Mohiuddin S M, Lucas B D, Stading J A, Stysich A M, Ryschon K Record Status This is a critical (...) abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology 32 anti-hypertensive drugs in 6 drug categories: diuretics, beta-blockers, alpha1-blockers, centrally acting alpha2-agonists, ACE inhibitors and calcium channel blockers. Type of intervention Primary Prevention Economic

NHS Economic Evaluation Database.1994

1130. Hypertension in the elderly: implications and generalizability of randomized trials

Hypertension in the elderly: implications and generalizability of randomized trials Hypertension in the elderly: implications and generalizability of randomized trials Hypertension in the elderly: implications and generalizability of randomized trials Mulrow C D, Cornell J A, Herrera C R, Kadri A, Farnett L, Aguilar C Authors' objectives To estimate the benefits of drug therapy, in terms of morbidity and mortality, for hypertensive elderly patients; to compare these benefits with effects (...) selection Study designs of evaluations included in the review Randomised controlled trials (RCTs) lasting more than 1 year. Specific interventions included in the review Antihypertensive drug therapy (mainly diuretics, but also beta-blockers and centrally-acting hypotensives) in trials lasting more than 1 year. Participants included in the review Hypertensive elderly persons aged over 60 years. The patients in the trial were healthier than the general population of elderly hypertensives. The

DARE.1994

1131. Lacidipine: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of hypertension

Lacidipine: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of hypertension Lacidipine: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of hypertension Lacidipine: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of hypertension Lee C R, Bryson H M Authors' objectives To assess the therapeutic potential of lacidipine (...) in hypertension. Searching MEDLINE, AdisBase, drug company databases and symposia proceedings were searched for relevant studies. Study selection Study designs of evaluations included in the review Various designs including non-comparative studies, placebo-controlled studies; comparative studies with other drugs appear to be double-blind randomised controlled trials (RCTs). Specific interventions included in the review Lacidipine at 1 to 8 mg/day in dose-titration studies; comparisons with hydrochlorothiazine

DARE.1994

1132. Do non-potassium sparing diuretics increase the risk of sudden cardiac death in hypertensive patients: recent evidence

Do non-potassium sparing diuretics increase the risk of sudden cardiac death in hypertensive patients: recent evidence Do non-potassium sparing diuretics increase the risk of sudden cardiac death in hypertensive patients: recent evidence Do non-potassium sparing diuretics increase the risk of sudden cardiac death in hypertensive patients: recent evidence Hoes A W, Grobbee D E, Peet T M, Lubsen J Authors' objectives To investigate whether non-potassium-sparing diuretics (NPSD) increase the risk (...) of sudden cardiac death in hypertensive patients. Searching The authors claimed 'an extensive literature search was carried out' and 'emphasis was put on data published since 1980', but no details were provided on the sources searched or the strategy used. Study selection Study designs of evaluations included in the review Controlled trials that reported sudden cardiac death as a separate end point were included. Specific interventions included in the review NPSDs (bendroflumethiazide, chlorthalidone

DARE.1994

1133. Drug treatment of hypertension in the elderly: a meta-analysis

Drug treatment of hypertension in the elderly: a meta-analysis Drug treatment of hypertension in the elderly: a meta-analysis Drug treatment of hypertension in the elderly: a meta-analysis Insua J T, Sacks H S, Lau T S, Lau J, Reitman D, Pagano D, Chalmers T C Authors' objectives To determine the effect of antihypertensive drug treatment on mortality and morbidity in the elderly. To evaluate the effects of disease severity and the age of the trial populations on mortality and morbidity (...) to determine whether treatment should be applied to all elderly subgroups. Searching MEDLINE was searched from 1980 to February 1992 using the keywords 'hypertension', 'elderly' or 'aged' and 'randomized controlled trials'. Additional searches were made on pertinent review articles, Current Contents (Clinical Medicine) and the references of retrieved articles. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs) of any anti-hypertensive drug treatments

DARE.1994

1134. Use of nifedipine in the hypertensive diseases of pregnancy

Use of nifedipine in the hypertensive diseases of pregnancy Use of nifedipine in the hypertensive diseases of pregnancy Use of nifedipine in the hypertensive diseases of pregnancy Levin A C, Doering P L, Hatton R C Authors' objectives To review available data about the use of nifedipine to treat hypertension in pregnancy. Searching MEDLINE, Excerpta Medica and BIOSIS Previews were searched from 1984 onwards for studies published in the English language, using the headings 'nifedipine (...) ', 'hypertension in pregnancy', 'uteroplacental blood flow', 'maternal/fetal hemodynamics', 'pre-eclampsia' and 'pregnancy outcome'. Study selection Study designs of evaluations included in the review The authors do not provide any details of the designs of the included studies. Specific interventions included in the review Acute administration of nifedipine, either alone or in conjunction with other blood-pressure medications including hydralazine, methyldopa, labetalol, atenolol, or methyldopa plus atenolol

DARE.1994

1135. Coordinating and standardizing long-term care: evaluation of the West of Scotland shared-care scheme for hypertension

Coordinating and standardizing long-term care: evaluation of the West of Scotland shared-care scheme for hypertension Coordinating and standardizing long-term care: evaluation of the West of Scotland shared-care scheme for hypertension Coordinating and standardizing long-term care: evaluation of the West of Scotland shared-care scheme for hypertension McGhee S M, McInnes G T, Hedley A J, Murray T S, Reid J L Record Status This is a critical abstract of an economic evaluation that meets (...) the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Shared general practitioner-hospital care for hypertensive patients. Type of intervention Treatment Economic study type Cost-effectiveness analysis Study population Outpatient and nurse practitioner clinic attenders in an urban area who have hypertension. Setting The

NHS Economic Evaluation Database.1994

1136. Cost-benefit of treating hypertension

Cost-benefit of treating hypertension Cost-benefit of treating hypertension Cost-benefit of treating hypertension Jonsson B G Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Antihypertensive drug treatment for the prevention (...) . Methods of combining primary studies Not stated. Investigation of differences between primary studies Not stated. Results of the review Antihypertensive treatment results in a reduction of 38% in stroke and 16% in coronary heart disease. Measure of benefits used in the economic analysis Cost per life year gained. Direct costs The cost of treating hypertension was taken from another study, but no details regarding its derivation were given. Some costs and resources were reported separately. Medical

NHS Economic Evaluation Database.1994

1137. The impact of age on the cost-effectiveness of hypertension treatment: an analysis of randomized drug trials

The impact of age on the cost-effectiveness of hypertension treatment: an analysis of randomized drug trials The impact of age on the cost-effectiveness of hypertension treatment: an analysis of randomized drug trials The impact of age on the cost-effectiveness of hypertension treatment: an analysis of randomized drug trials Johannesson M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary (...) of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Drug therapies for the treatment of hypertension. Actual therapies were not specified. Type of intervention Primary prevention Economic study type Cost-effectiveness analysis Study population Men and women with hypertension, aged 38-76, with entry diastolic blood pressure (DBP) of 91-122 mmHg. Setting Primary care. The economic study was carried

NHS Economic Evaluation Database.1994

1138. Effects of low dose versus conventional dose thiazide diuretic on insulin action in essential hypertension.

Effects of low dose versus conventional dose thiazide diuretic on insulin action in essential hypertension. 7818648 1994 09 26 1994 09 26 2013 11 21 0959-8138 309 6949 1994 Jul 23 BMJ (Clinical research ed.) BMJ Effects of low dose versus conventional dose thiazide diuretic on insulin action in essential hypertension. 226-30 To see whether low dose thiazide diuretics given to patients with essential hypertension might avoid the adverse metabolic consequences seen with conventional doses. Double (...) blind randomised crossover study of two 12 week treatment periods with either low dose (1.25 mg) or conventional dose (5.0 mg) bendrofluazide given after a six week placebo run in period. Outpatient clinics serving the greater Belfast area. 16 white non-diabetic patients (9 male) under 65 with essential hypertension recruited from general practices within the greater Belfast area. Systolic and diastolic blood pressure and peripheral and hepatic insulin action. One man failed to complete the study

BMJ1994 Full Text: Link to full Text with Trip Pro

1139. Reduction in blood pressure with a low sodium, high potassium, high magnesium salt in older subjects with mild to moderate hypertension.

Reduction in blood pressure with a low sodium, high potassium, high magnesium salt in older subjects with mild to moderate hypertension. 7920126 1994 10 27 1994 10 27 2013 11 21 0959-8138 309 6952 1994 Aug 13 BMJ (Clinical research ed.) BMJ Reduction in blood pressure with a low sodium, high potassium, high magnesium salt in older subjects with mild to moderate hypertension. 436-40 To examine the effect of a reduced sodium and increased potassium and magnesium intake on blood (...) pressure. Randomised double blind placebo controlled trial. General population of a suburb of Rotterdam. 100 men and women between 55 and 75 years of age with untreated mild to moderate hypertension. During 24 weeks the intervention group received a mineral salt (sodium: potassium: magnesium 8:6:1) and foods prepared with the mineral salt. Controls received common salt and foods. Change in blood pressure. Complete follow up was achieved for 97 of the 100 randomised subjects. Systolic blood pressure (mean

BMJ1994 Full Text: Link to full Text with Trip Pro

1140. Effect of stress management on blood pressure in mild primary hypertension.

Effect of stress management on blood pressure in mild primary hypertension. 8490471 1993 06 17 1993 06 17 2016 11 23 0959-8138 306 6883 1993 Apr 10 BMJ (Clinical research ed.) BMJ Effect of stress management on blood pressure in mild primary hypertension. 963-6 To establish whether stress management had a larger effect than a control treatment on resting blood pressure, ambulatory blood pressure, and left ventricular mass. A 12 week baseline period of habituation to measurement of blood (...) pressure was followed by randomisation to either stress management or mild exercise for six months and follow up six months later. General practice, district general hospital, and medical school. Of the 184 patients aged under 60 with mild primary hypertension who entered the baseline habituation period, 88 were excluded because they failed to meet the entry criteria or they withdrew from the study. The remaining 46 men and 50 women underwent treatment. 10 clinical sessions and daily practice at home of either

BMJ1993 Full Text: Link to full Text with Trip Pro