Latest & greatest articles for hydroxyzine

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Top results for hydroxyzine

1. Hydroxyzine

Hydroxyzine Top results for hydroxyzine - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2 (...) ) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for hydroxyzine The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms

2018 Trip Latest and Greatest

2. Hydroxyzine for generalised anxiety disorder. (PubMed)

Hydroxyzine for generalised anxiety disorder. Generalised anxiety disorder (GAD) is a common chronic long-term psychiatric disorder, particularly frequent in primary care. There are several treatment options available, both non-pharmacological (i.e. cognitive behavioral therapy) and pharmacological. Among the pharmacological interventions, antidepressants, buspirone and benzodiazepines (BDZs) have been studied in GAD. Hydroxyzine is an anti-histamine medication which has been used (...) in the treatment of anxiety.1. To determine the efficacy of hydroxyzine in comparison with placebo or any other active agent in alleviating the acute symptoms of GAD. 2. To review acceptability of treatment with hydroxyzine in comparison with placebo or any other active agent. 3. To investigate the adverse effects of hydroxyzine in comparison with other active agents.The Cochrane Depression, Anxiety and Neurosis Group's controlled trial registers (CCDANCTR-Studies and CCDANCTR-References) were searched on 1

2010 Cochrane

3. Hydroxyzine may be an Acceptable Treatment Option for Children with Sleep Bruxism

Hydroxyzine may be an Acceptable Treatment Option for Children with Sleep Bruxism UTCAT2682, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Hydroxyzine may be an Acceptable Treatment Option for Children with Sleep Bruxism Clinical Question Can hydroxyzine be used as a treatment option for children suffering from sleep bruxism compared to no treatment? Clinical Bottom Line Children presenting sleep bruxism showed (...) a clinically significant decrease in reported bruxism when taking a dose of hydroxyzine nightly. In these trials hydroxyzine treatment caused no adverse side effects and can be considered a viable treatment option. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Ghanizadeh/2013 Three Children Case series Key results This study examined three children with sleep bruxism that were given 10-25mg of hydroxyzine

2014 UTHSCSA Dental School CAT Library

4. Hydroxyzine: other options are preferable

Hydroxyzine: other options are preferable Prescrire IN ENGLISH - Spotlight ''Hydroxyzine: other options are preferable'', 1 July 2015 {1} {1} {1} | | > > > Hydroxyzine: other options are preferable Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight Hydroxyzine: other options are preferable Hydroxyzine, an antihistamine, is not a first-choice drug (...) . Other drugs have a more favourable harm-benefit balance in some of its approved indications (urticaria, anxiety, insomnia). Hydroxyzine is an antihistamine with sedative and atropine-like effects. Taken orally, it is authorized in adults and children, especially for minor manifestations of anxiety, and in the symptomatic treatment of urticaria. In children over the age of 3 it is authorized as a second-line treatment for some insomnias, when behavioural measures alone are insufficient. When an oral

2015 Prescrire

5. Hydroxyzine may be safe and effective in generalised anxiety disorder

Hydroxyzine may be safe and effective in generalised anxiety disorder Hydroxyzine may be safe and effective in generalised anxiety disorder | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username (...) * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Hydroxyzine may be safe and effective in generalised anxiety disorder Article Text Therapeutics Hydroxyzine may be safe and effective in generalised anxiety disorder Free Shahin Akhondzadeh , PhD , Professor Associate Statistics from Altmetric.com

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2004 Evidence-Based Mental Health

6. MANAGEMENT OF EMOTIONAL DISTURBANCES—Use of Hydroxyzine (Atarax®) in General Practice (PubMed)

MANAGEMENT OF EMOTIONAL DISTURBANCES—Use of Hydroxyzine (Atarax®) in General Practice Forty-one patients with anxiety and tension or various conditions associated with neuroses were treated with hydroxyzine hydrochloride tablets. Of the 41 patients, eight had an excellent response, 14 a good response, 16 were improved and three responded poorly. The only side reaction in this series was temporary drowsiness which, in the majority of patients, ceased after therapy was steadily continued

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1958 California Medicine

7. Recent clinical trials of hydroxyzine in generalized anxiety disorder. (PubMed)

Recent clinical trials of hydroxyzine in generalized anxiety disorder. Numerous clinical trials in the 1960s and 1970s have attested to the anxiolytic efficacy of hydroxyzine and its beneficial effect on sleep, as well as in reducing stress and anxiety associated with coronary disease. Experience with hydroxyzine has also shown a lack of organ toxicity and an absence of dependency. Recent controlled clinical trials with hydroxyzine have confirmed its efficacy (at a fixed dose of 50 mg (...) ) in generalized anxiety disorder--superiority over placebo on all anxiety measures from the first week with early target symptoms which are grouped in a cognitive component of anxiety. Efficacy was maintained throughout the 4 weeks of treatment and after abrupt discontinuation. In another controlled trial vs. lorazepam, hydroxyzine demonstrated greater and more rapid cognitive improvement.

1998 Acta psychiatrica Scandinavica. Supplementum

8. A preliminary randomised double-blind placebo-controlled clinical trial of hydroxyzine for treating sleep bruxism in children. (PubMed)

A preliminary randomised double-blind placebo-controlled clinical trial of hydroxyzine for treating sleep bruxism in children. This is a randomised placebo-controlled clinical trial investigating the efficacy of hydroxyzine for treating parent-reported sleep bruxism in children. Participants of this trial were 30 patients randomly allocated to one of the two groups in a ratio of 1:2. One group received hydroxyzine and the other group received placebo. The outcome measures were Visual Analogue (...) Scale test and Clinical Global Severity scale. Assessments occurred at baseline and at the end of week 4. The side effects of drugs were assessed using a checklist. The number of children in the hydroxyzine and placebo groups was 21 and 9, respectively. The mean age of children in the hydroxyzine and placebo groups was 8·4(s.d. = 3·3) and 6·5(s.d. = 1·5) years, respectively. Hydroxyzine more than placebo decreased bruxism score (3·8 versus 2·2). No serious adverse effect was reported. Current

2013 Journal of oral rehabilitation

9. Comparing the Effect of Prazosin and Hydroxyzine on Sleep Quality in Patients Suffering from Posttraumatic Stress Disorder. (PubMed)

Comparing the Effect of Prazosin and Hydroxyzine on Sleep Quality in Patients Suffering from Posttraumatic Stress Disorder. In light of the high prevalence of sleep disorders in patients suffering from posttraumatic stress disorder (PTSD), this study sought to compare the effect of prazosin and hydroxyzine on sleep quality in this patient group.A total of 100 patients suffering from PTSD were assessed (mean age = 35.51 years, SD = 6.41; 28% females). Next, they were randomly assigned to one (...) of three treatment groups: prazosin (33 patients), hydroxyzine (34 patients) or placebo (33 patients). The trial lasted for 8 weeks. The patients' sleep quality was assessed using the Pittsburgh Sleep Quality Index. Items taken from the Mini International Neuropsychiatric Interview were used to operationalize PTSD.Compared to controls, patients treated with prazosin and hydroxyzine reported improved sleep and less nightmares. Improvement was greatest in patients treated with prazosin compared

2014 Neuropsychobiology

10. Comparison of Avena Sativa, Vinegar, and Hydroxyzine for Uremic Pruritus of Hemodialysis Patients: a Crossover Randomized Clinical Trial. (PubMed)

Comparison of Avena Sativa, Vinegar, and Hydroxyzine for Uremic Pruritus of Hemodialysis Patients: a Crossover Randomized Clinical Trial. Uremic pruritus is a common complication in patients with chronic kidney disease. While its cause is not known for certain, different treatments are currently applied. This study aimed to compare the effects of Avena sativa, diluted vinegar, and hydroxyzine on the reduction of uremic pruritus.In this crossover randomized clinical trial, 23 hemodialysis (...) patients with uremic pruritus were randomly divided into 3 groups. The first group was treated with Avena sativa lotion, twice a day, for as long as 2 weeks; the second group received diluted vinegar; and the third group took hydroxyzine tablets for the same time span. After 3-day-long washout periods, the therapeutic methods were crossed over. The data were collected by a pruritus scale and a visual analogue scale, which were completed before and after the interventions.Avena sativa lotion

2015 Iranian journal of kidney diseases

11. Chloral Hydrate, Chloral Hydrate - Promethazine and Chloral Hydrate -Hydroxyzine Efficacy in Electroencephalography Sedation. (PubMed)

Chloral Hydrate, Chloral Hydrate - Promethazine and Chloral Hydrate -Hydroxyzine Efficacy in Electroencephalography Sedation. To compare efficacy and safety of chloral hydrate (CH), chloral hydrate and promethazine (CH + P) and chloral hydrate and hydroxyzine (CH + H) in electroencephalography (EEG) sedation.In a parallel single-blinded randomized clinical trial, ninety 1-7 y-old uncooperative kids who were referred to Pediatric Neurology Clinic of Shahid Sadoughi University, Yazd, Iran from (...) April through August 2012, were randomly assigned to receive 40 mg/kg of chloral hydrate or 40 mg/kg of chloral hydrate and 1 mg/kg of promethazine or 40 mg/kg of chloral hydrate and 2 mg/kg of hydroxyzine. The primary endpoint was efficacy in sufficient sedation (obtaining four Ramsay sedation score) and successful completion of EEG. Secondary endpoint was clinical adverse events.Thirty nine girls (43.3 %) and 51 boys (56.7 %) with mean age of 3.34 ± 1.47 y were assessed. Sufficient sedation

2014 Indian journal of pediatrics

12. The effects of nitrous oxide on behavior and physiological parameters during conscious sedation with a moderate dose of chloral hydrate and hydroxyzine. (PubMed)

The effects of nitrous oxide on behavior and physiological parameters during conscious sedation with a moderate dose of chloral hydrate and hydroxyzine. The purpose of this study was to determine differences in heart rate (HR), blood pressure (BP), peripheral oxygen saturation (pO2), expired CO2 (CO2), and behavior (using two scales) comparing nitrous oxide/oxygen (N2O) with oxygen (O2) alone in 20 children (mean age 45 +/- 5.1 months) sedated with chloral hydrate (CH) and hydroxyzine (...) in a double-blind crossover design. Administration of CH (40 mg/kg) and hydroxyzine (2 mg/kg) was held constant for each patient visit; however, N2O (50%) was administered during one visit and O2 (100%) at the other in a randomly determined manner. Physiologic and behavioral parameters were collected during eight specific procedural events (e.g., administration of local anesthesia). Data were analyzed with a repeated-measures ANOVA, one-way ANOVA, t-test, Kruskal Wallis ANOVA, and descriptive statistics

1996 Pediatric dentistry

13. A multicentre double-blind comparison of hydroxyzine, buspirone and placebo in patients with generalized anxiety disorder. (PubMed)

A multicentre double-blind comparison of hydroxyzine, buspirone and placebo in patients with generalized anxiety disorder. The efficacy of hydroxyzine and buspirone, controlled by placebo, was investigated in a double-blind, parallel group, multicentre study conducted in France and the UK. A total of 244 patients with generalised anxiety disorder in primary care was allocated randomly to treatments with hydroxyzine (12.5 mg morning and mid-day, 25 mg evening), buspirone (5 mg morning and mid (...) variable showed a significant difference only between hydroxyzine and placebo with respect to improvement on the Hamilton Anxiety Scale (10.75 versus 7.23 points, respectively). Secondary variables such as CGI and self-ratings (HAD scale) showed both hydroxyzine and buspirone to be more efficacious than placebo. Thus, hydroxyzine is a useful treatment for GAD.

1998 Psychopharmacology

14. [Value of hydroxyzine in generalized anxiety disorder: controlled double-blind study versus placebo]. (PubMed)

[Value of hydroxyzine in generalized anxiety disorder: controlled double-blind study versus placebo]. A multi-centre study was designed to evaluate the efficacy of hydroxyzine in the treatment of patients presenting a generalized anxiety disorder (GAD). One hundred and thirty three patients, suffering from a GAD (according to DSM III-R criteria with 6 months duration criteria), were enrolled in a randomised, double-blind, hydroxyzine (50 mg/day) versus placebo, over a 4-week trial period (...) . By the end of the first week, the decrease of anxiety scores was significant for the hydroxyzine group, as compared to placebo (in respect of all rating criteria of anxiety). The statistical superiority for hydroxyzine continued to the end of the 4-weeks study period, and persisted at a further evaluation a week after abrupt discontinuation of active treatment. The tolerance evaluation showed that side effects were reported in 52% of hydroxyzine group versus 35% of placebo group. The most commun side

1995 L'Encéphale

15. Sedative Effect of Oral Midazolam/Hydroxyzine versus Chloral Hydrate/Hydroxyzine on 2-6 Year-Old Uncooperative Dental Patients: A Randomized Clinical Trial. (PubMed)

Sedative Effect of Oral Midazolam/Hydroxyzine versus Chloral Hydrate/Hydroxyzine on 2-6 Year-Old Uncooperative Dental Patients: A Randomized Clinical Trial. Different drugs are used for conscious sedation in pediatric dentistry either single or in combination. This study assessed the comparative effect of midazolam/hydroxyzine and chloral hydrate/hydroxyzine on 2-6 year-old uncooperative children needing dental treatment.A double blind cross-over randomized clinical trial was designed and 16 (...) children aged 2-6 years with ASA1 status who were judged with negative to definitely negative behavior (according to Frankl) were chosen. Cases were divided randomly into two groups. The first group received midazolam/hydroxyzine (MH) at the first visit while the second group received chloral hydrate/hydroxyzine (CHH) as the first medication. Both groups received the other regimen at the second visit. Midazolam 0.5mg/kg and chloral hydrate 50mg/kg with 1mg/kg hydroxyzine were administered. Cases were

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2014 Journal of dentistry (Tehran, Iran)

16. Chloral hydrate versus hydroxyzine HCL for sedation prior to pediatric sleep EEG recording. (PubMed)

Chloral hydrate versus hydroxyzine HCL for sedation prior to pediatric sleep EEG recording. The sleep electroencephalogram (EEG) can reveal certain epileptiform activity patterns and facilitate localization of the focus. Sedation is often required for sleep EEG recording in pediatric patients, but there is no consensus on the optimal sedative. Hydroxyzine HCL (HH) and chloral hydrate (CH) are popular sedatives, but HH is rarely used for pediatric sleep EEG recording. The goal

2013 The International journal of neuroscience

17. Efficacy and safety of hydroxyzine in the treatment of generalized anxiety disorder: a 3-month double-blind study. (PubMed)

Efficacy and safety of hydroxyzine in the treatment of generalized anxiety disorder: a 3-month double-blind study. The prevalence of generalized anxiety disorder (GAD) represents an important public health issue. Hydroxyzine, an antagonist of histamine receptors, showed both efficacy and safety in previous short-term double-blind studies over placebo in this pathology. The aim of the current study was to confirm those positive results over a 3-month period in adult outpatients.This multicenter (...) , parallel (hydroxyzine [50 mg/day]; bromazepam [6 mg/day]), randomized, double-blind, placebo-controlled trial included 2 weeks of single-blind run-in placebo, 12 weeks of double-blind randomized treatment, and 4 weeks of single-blind run-out placebo. Three hundred thirty-four of 369 selected outpatients with a diagnosis of GAD according to DSM-IV criteria and a Hamilton Rating Scale for Anxiety (HAM-A) total score >/= 20 were randomized before entering the double-blind period. The primary outcome

2002 Journal of Clinical Psychiatry

18. A prospective study of 2 sedation regimens in children: chloral hydrate, meperidine, and hydroxyzine versus midazolam, meperidine, and hydroxyzine. (PubMed)

A prospective study of 2 sedation regimens in children: chloral hydrate, meperidine, and hydroxyzine versus midazolam, meperidine, and hydroxyzine. The aim of this study was to compare both the behavioral and physiological effects of 2 drug regimens in children: chloral hydrate (CH), meperidine (M), and hydroxyzine (H) (regimen A) versus midazolam (MZ), M, and H (regimen B). Patients between 24 and 54 months of age were examined by crossover study design. Behavior was analyzed objectively

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2006 Anesthesia progress

19. A randomized double-blinded trial of chloral hydrate with or without hydroxyzine versus placebo for pediatric dental sedation. (PubMed)

A randomized double-blinded trial of chloral hydrate with or without hydroxyzine versus placebo for pediatric dental sedation. Chloral hydrate and hydroxyzine are a drug combination frequently used by practitioners to sedate pediatric dental patients, but their effectiveness has not been compared to a negative control group in humans. The aim of this crossover, double-blinded study was to evaluate the effect of these drugs compared to a placebo, administered to young children for dental (...) treatment. Thirty-five dental sedation sessions were carried out on 12 uncooperative ASA I children aged less than 5 years old. In each session patients were randomly assigned to groups P (placebo), CH (chloral hydrate 75 mg/kg) and CHH (chloral hydrate 50 mg/kg plus hydroxyzine 2.0 mg/kg). Vital signs and behavioral variables were evaluated every 15 min. Comparisons were statistically analyzed using Friedman and Wilcoxon tests. P, CH and CHH had no differences concerning vital signs, except

2007 Brazilian dental journal

20. Hydroxyzine (Atarax, Ucerax): risk of QT interval prolongation and Torsade de Pointes

Hydroxyzine (Atarax, Ucerax): risk of QT interval prolongation and Torsade de Pointes Hydroxyzine (Atarax, Ucerax): risk of QT interval prolongation and Torsade de Pointes - GOV.UK GOV.UK uses cookies to make the site simpler. or Search Hydroxyzine (Atarax, Ucerax): risk of QT interval prolongation and Torsade de Pointes The maximum adult daily dose of hydroxyzine is now 100 mg. Do not prescribe hydroxyzine to people with a prolonged QT interval or risk factors for QT interval prolongation (...) . Published 29 April 2015 From: Therapeutic area: , When using hydroxyzine: do not prescribe hydroxyzine to people with a prolonged QT interval or who have risk factors for QT interval prolongation (see below) avoid use in the elderly - they are more susceptible than younger patients to the side effects of hydroxyzine consider the risks of QT interval prolongation and Torsade de Pointes before prescribing to patients taking medicines that lower heart rate or potassium levels the maximum daily dose is now

2015 MHRA Drug Safety Update