Latest & greatest articles for hiv

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Top results for hiv

41. ‘Why would you promote something that is less percent safer than a condom?’: Perspectives on partially effective HIV prevention technologies among key populations in South Africa (PubMed)

‘Why would you promote something that is less percent safer than a condom?’: Perspectives on partially effective HIV prevention technologies among key populations in South Africa 30360675 2018 12 14 2018 12 14 1813-4424 15 1 2018 12 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance SAHARA J 'Why would you promote something that is less percent safer than a condom?': Perspectives on partially effective HIV prevention technologies among key populations in South Africa. 179 (...) -186 10.1080/17290376.2018.1536561 New biomedical prevention technologies (NPTs) for HIV, including oral Pre-Exposure Prophylaxis, and vaginal and rectal microbicides and HIV vaccines in development, may contribute substantially to controlling the HIV epidemic. However, their effectiveness is contingent on product acceptability and adherence. We explored perceptions and understanding of partially effective NPTs with key populations in South African townships. From October 2013 to February 2014, we

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2018 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance

42. ‘They care rudely!’: resourcing and relational health system factors that influence retention in care for people living with HIV in Zambia (PubMed)

‘They care rudely!’: resourcing and relational health system factors that influence retention in care for people living with HIV in Zambia 30483408 2018 11 28 2059-7908 3 5 2018 BMJ global health BMJ Glob Health 'They care rudely!': resourcing and relational health system factors that influence retention in care for people living with HIV in Zambia. e001007 10.1136/bmjgh-2018-001007 Despite access to free antiretroviral therapy (ART), many HIV-positive Zambians disengage from HIV care. We (...) sought to understand how Zambian health system 'hardware' (tangible components) and 'software' (work practices and behaviour) influenced decisions to disengage from care among 'lost-to-follow-up' patients traced by a larger study on their current health status. We purposively selected 12 facilities, from 4 provinces. Indepth interviews were conducted with 69 patients across four categories: engaged in HIV care, disengaged from care, transferred to another facility and next of kin if deceased. We also

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2018 BMJ global health

43. An evaluation of the innovative potentials of a HIV pilot exploring medical pluralism in rural South Africa (PubMed)

An evaluation of the innovative potentials of a HIV pilot exploring medical pluralism in rural South Africa 30340450 2018 12 14 2018 12 14 1813-4424 15 1 2018 12 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance SAHARA J An evaluation of the innovative potentials of a HIV pilot exploring medical pluralism in rural South Africa. 164-178 10.1080/17290376.2018.1536560 This article reflects on an internal evaluation undertaken to estimate the potentials of a community-university (...) pilot project to be developed into a bonafide innovation that can be applied at scale. The focus of the community-university partnership has been to reduce the unintended consequences of medical pluralism on the HIV and AIDS epidemic in Waterberg district, Limpopo Province, South Africa. Despite promising outputs from the partnership - including an increase in adherence to antiretroviral therapy and a reduction in stigma among traditionalists living with HIV - the partnership wished to establish

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2018 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance

44. Determinants of disclosure and non-disclosure of HIV-positive status, by pregnant women in rural South Africa (PubMed)

Determinants of disclosure and non-disclosure of HIV-positive status, by pregnant women in rural South Africa 30324859 2018 12 14 2018 12 14 1813-4424 15 1 2018 12 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance SAHARA J Determinants of disclosure and non-disclosure of HIV-positive status, by pregnant women in rural South Africa. 155-163 10.1080/17290376.2018.1529613 Disclosure of HIV status remains one of the major challenges to the effectiveness of the prevention of mother (...) to child transmission of HIV in rural areas in South Africa. This study aimed at assessing the determinants of HIV status disclosure among HIV infected pregnant women who have disclosed their HIV status to someone, as well as among those who have disclosed to their partners. Cross-sectional data was collected from 673 HIV sero-positive pregnant women receiving antenatal care services at 12 Community Health Centers in Mpumalanga province. Results indicated that over two-thirds (72.1%) disclosed

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2018 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance

45. Mechanisms That Contribute to a Profound Reduction of the HIV-1 Reservoir After Allogeneic Stem Cell Transplant. (PubMed)

Mechanisms That Contribute to a Profound Reduction of the HIV-1 Reservoir After Allogeneic Stem Cell Transplant. Background: The multifactorial mechanisms associated with radical reductions in HIV-1 reservoirs after allogeneic hematopoietic stem cell transplant (allo-HSCT), including a case of HIV cure, are not fully understood. Objective: To investigate the mechanism of HIV-1 eradication associated with allo-HSCT. Design: Nested case series within the IciStem observational cohort. Setting (...) : Multicenter European study. Participants: 6 HIV-infected, antiretroviral-treated participants who survived more than 2 years after allo-HSCT with CCR5 wild-type donor cells. Measurements: HIV DNA analysis, HIV RNA analysis, and quantitative viral outgrowth assay were performed in blood, and HIV DNA was also measured in lymph nodes, ilea, bone marrow, and cerebrospinal fluid. A humanized mouse model was used for in vivo detection of the replication-competent blood cell reservoir. HIV-specific antibodies

2018 Annals of Internal Medicine

46. Effects of adolescent exposure to behaviour change interventions on their HIV risk reduction in Northern Malawi: a situation analysis (PubMed)

Effects of adolescent exposure to behaviour change interventions on their HIV risk reduction in Northern Malawi: a situation analysis 30278823 2018 12 14 2018 12 14 1813-4424 15 1 2018 12 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance SAHARA J Effects of adolescent exposure to behaviour change interventions on their HIV risk reduction in Northern Malawi: a situation analysis. 146-154 10.1080/17290376.2018.1529612 Understanding adolescents' translation of HIV and AIDS-related (...) behaviour change interventions (BCI) knowledge and skills into expected behavioural outcomes helps us appreciate behaviour change dynamics among young people and informs evidence-based programming. We explored the effects of adolescents' exposure to BCI on their HIV risk reduction in selected schools in Nkhatabay and Mzimba districts and Mzuzu city in Northern Malawi. The study used questionnaires as instruments. Data were collected between January and April 2017. Adolescent boys and girls [n = 552

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2018 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance

47. Doravirine (Pifeltro) - To treat HIV-1 infection in adult patients

Doravirine (Pifeltro) - To treat HIV-1 infection in adult patients Drug Approval Package: PIFELTRO (doravirine) U.S. Department of Health and Human Services Search FDA Submit search Drug Approval Package: PIFELTRO (doravirine) Company: Merck Sharp & Dohme Corp. Application Number: 210806 & 210807 Approval Date: 08/30/2018 Persons with disabilities having problems accessing the PDF files below may call (301) 796-3634 for assistance. FDA Approval Letter and Labeling (PDF) (PDF) FDA Application

2018 FDA - Drug Approval Package

48. Using strategic information for action: lessons from the HIV/AIDS response in Vietnam (PubMed)

Using strategic information for action: lessons from the HIV/AIDS response in Vietnam 30294455 2018 11 14 2059-7908 3 5 2018 BMJ global health BMJ Glob Health Using strategic information for action: lessons from the HIV/AIDS response in Vietnam. e000793 10.1136/bmjgh-2018-000793 Son Vo Hai VH Vietnam Administration on HIV/AIDS Control, Vietnam Ministry of Health, Hanoi, Vietnam. Abdul-Quader Abu A Center for Global Health, Centers for Disease Control and Prevention, Hanoi, Viet Nam. Suthar (...) Amitabh Bipin AB 0000-0001-9756-6593 Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. eng Journal Article 2018 09 26 England BMJ Glob Health 101685275 2059-7908 Hiv epidemiology geographic information systems health systems Competing interests: None declared. 2018 02 21 2018 05 07 2018 07 13 2018 10 9 6 0 2018 10 9 6 0 2018 10 9 6 1 epublish 30294455 10.1136/bmjgh-2018-000793 bmjgh-2018-000793 PMC6169661 Bull World Health Organ. 2010 Jan;88(1):58-65 20428354

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2018 BMJ global health

49. Stick To It: pilot study results of an intervention using gamification to increase HIV screening among young men who have sex with men in California (PubMed)

Stick To It: pilot study results of an intervention using gamification to increase HIV screening among young men who have sex with men in California 30363751 2018 11 14 2306-9740 4 2018 mHealth Mhealth Stick To It: pilot study results of an intervention using gamification to increase HIV screening among young men who have sex with men in California. 40 10.21037/mhealth.2018.09.04 In the United States, young men who have sex with men (YMSM) experience a disproportionate burden of HIV and (...) and potentially increases repeat HIV screening. Eligible YMSM were: (I) 18-26 years, (II) born as and/or self-identified as male, (III) reported male sexual partners, and (IV) lived in a zip code adjacent to one of the two study clinics in Oakland and Hollywood, California. The gamification intervention, Stick To It , had four components: (I) recruitment (clinic-based and online), (II) online enrollment, (III) online activities, and (IV) 'real-world' activities at the clinic. Participants earned points

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2018 mHealth

50. Exploring the acceptability of Option B plus among HIV-positive Nigerian women engaged and not engaged in the prevention of mother-to-child transmission of HIV cascade: a qualitative study (PubMed)

Exploring the acceptability of Option B plus among HIV-positive Nigerian women engaged and not engaged in the prevention of mother-to-child transmission of HIV cascade: a qualitative study 30253709 2018 12 14 2018 12 14 1813-4424 15 1 2018 12 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance SAHARA J Exploring the acceptability of Option B plus among HIV-positive Nigerian women engaged and not engaged in the prevention of mother-to-child transmission of HIV cascade: a (...) qualitative study. 128-137 10.1080/17290376.2018.1527245 The acceptability of lifelong antiretroviral therapy (ART) among HIV-positive women in high-burden Nigeria, is not well-known. We explored readiness of users and providers of prevention of mother-to-child transmission of HIV (PMTCT) services to accept lifelong ART -before Option B plus was implemented in Nigeria. We conducted 142 key informant interviews among 100 PMTCT users (25 pregnant-newly-diagnosed, 26 pregnant-in-care, 28 lost-to-follow-up

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2018 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance

51. Factors associated with knowledge and awareness of HIV/AIDS among married women in Bangladesh: evidence from a nationally representative survey (PubMed)

Factors associated with knowledge and awareness of HIV/AIDS among married women in Bangladesh: evidence from a nationally representative survey 30249174 2018 12 14 2018 12 14 1813-4424 15 1 2018 12 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance SAHARA J Factors associated with knowledge and awareness of HIV/AIDS among married women in Bangladesh: evidence from a nationally representative survey. 121-127 10.1080/17290376.2018.1523022 Women in Bangladesh share a greater risk (...) of Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS) infection compared to men. Levels of knowledge and awareness largely contribute to the prevalence of the HIV epidemic and its consequences. So, it is required to conduct studies based on most recent data to explore the determinants of HIV awareness. Therefore, we aimed to find the awareness level and factors influencing HIV related awareness among the married women in Bangladesh. We used data from 2014 Bangladesh Demographic and Health Survey

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2018 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance

52. Integration of HIV and reproductive health services in public sector facilities: analysis of client flow data over time in Kenya (PubMed)

Integration of HIV and reproductive health services in public sector facilities: analysis of client flow data over time in Kenya 30245866 2018 11 14 2059-7908 3 5 2018 BMJ global health BMJ Glob Health Integration of HIV and reproductive health services in public sector facilities: analysis of client flow data over time in Kenya. e000867 10.1136/bmjgh-2018-000867 Integration of HIV/AIDS with reproductive health (RH) services can increase the uptake and efficiency of services, but gaps (...) an intervention to strengthen HIV service integration with family planning (FP); and 10 266 visits in districts where half the facilities received an HIV-postnatal care intervention in 2009-2010. We tracked the proportion of all visits in which: (1) an HIV service (testing, counselling or treatment) was received together with an RH service (FP counselling or provision, antenatal care, or postnatal care); (2) the client received HIV counselling. Levels of integrated HIV-RH services and HIV counselling were

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2018 BMJ global health

53. Validation of a Swahili version of the World Health Organization 5-item well-being index among adults living with HIV and epilepsy in rural coastal Kenya (PubMed)

Validation of a Swahili version of the World Health Organization 5-item well-being index among adults living with HIV and epilepsy in rural coastal Kenya 30214943 2018 11 14 2397-0642 3 2018 Global health research and policy Glob Health Res Policy Validation of a Swahili version of the World Health Organization 5-item well-being index among adults living with HIV and epilepsy in rural coastal Kenya. 26 10.1186/s41256-018-0081-z The purpose of this study was to evaluate the psychometric (...) properties of the World Health Organization's five item well-being index (WHO-5) when administered to adults living with HIV or epilepsy in a rural setting at the coast of Kenya. A case control study design was conducted among 230 adults aged 18-50 years, who comprised 147 cases (63 living with epilepsy and 84 living with HIV) and 83 healthy controls. The participants were administered to a face-to-face interview during which they completed the Swahili version of WHO-5 well-being index, the Major

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2018 Global health research and policy

54. Health-related quality of life and associated factors in adults living with HIV in Rwanda (PubMed)

Health-related quality of life and associated factors in adults living with HIV in Rwanda 30200815 2018 12 14 2018 12 14 1813-4424 15 1 2018 12 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance SAHARA J Health-related quality of life and associated factors in adults living with HIV in Rwanda. 110-120 10.1080/17290376.2018.1520144 In Rwanda, as in other sub-Saharan African (SSA) countries, life expectancy of people living with HIV (PLWH) has increased dramatically as a result (...) of combined antiretroviral therapy (cART). People living with HIV can now live longer but with increasing rates of non-communicable diseases (NCDs). Thus, prevention of NCD comorbidities in PWLHI is crucial to maintain and gain health-related benefits and to maximise the health-related quality of life (HRQOL) in the long-term management of PLWH. This study determines the association between physical and mental health-related dimensions of quality of life (QOL) with behavioural and biological risk factors

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2018 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance

55. Significant Association of Aldosterone and Liver Fat Among HIV-Infected Individuals With Metabolic Dysregulation (PubMed)

Significant Association of Aldosterone and Liver Fat Among HIV-Infected Individuals With Metabolic Dysregulation 30283827 2018 11 14 2472-1972 2 10 2018 Oct 01 Journal of the Endocrine Society J Endocr Soc Significant Association of Aldosterone and Liver Fat Among HIV-Infected Individuals With Metabolic Dysregulation. 1147-1157 10.1210/js.2018-00194 Fatty liver disease is increased among individuals with HIV. We sought to explore how aldosterone, a key hormone linked to insulin resistance (...) and inflammation, relates to liver fat in the large population of individuals with HIV and metabolic abnormalities. Forty-six individuals with HIV and increased waist circumference and dysglycemia were assessed for liver fat using proton magnetic resonance spectroscopy. Serum aldosterone level was obtained following strictly controlled posture conditions and a standardized sodium diet and was related to liver fat. Among the entire group [median (interquartile range) liver fat: 5% (3%, 12%) and homeostatic

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2018 Journal of the Endocrine Society

56. Health care users’ knowledge, attitudes and perceptions of HIV self-testing at selected gateway clinics at eThekwini district, KwaZulu-Natal province, South Africa (PubMed)

Health care users’ knowledge, attitudes and perceptions of HIV self-testing at selected gateway clinics at eThekwini district, KwaZulu-Natal province, South Africa 30175655 2018 12 24 2018 12 24 1813-4424 15 1 2018 12 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance SAHARA J Health care users' knowledge, attitudes and perceptions of HIV self-testing at selected gateway clinics at eThekwini district, KwaZulu-Natal province, South Africa. 103-109 10.1080/17290376.2018.1517607 (...) Progress in promoting knowledge of HIV status has been made globally, but half of all people living with HIV are still unaware of their HIV status. It is argued the new innovative HIV self-testing strategy could increase the uptake of HIV testing among the people. The aim of the study was to assess outpatients' health care user's knowledge, attitudes and perceptions towards HIV self-testing (HIVST) at selected Gateway clinics at eThekwini District, KwaZulu-Natal Province, South Africa. The objectives

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2018 SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance

57. Bictegravir-emtricitabine-tenofovir alafenamide (Biktarvy) - For the treatment of adults infected with HIV-1 without any known mutations associated with resistance to the individual components.

Bictegravir-emtricitabine-tenofovir alafenamide (Biktarvy) - For the treatment of adults infected with HIV-1 without any known mutations associated with resistance to the individual components. Published 10 September 2018 1 bictegravir 50mg / emtricitabine 200mg / tenofovir alafenamide 25mg film- coated tablet (Biktarvy ® ) SMC2093 Gilead Sciences Ltd 10 August 2018 The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and advises NHS Boards and Area Drug (...) and Therapeutic Committees (ADTCs) on its use in NHS Scotland. The advice is summarised as follows: ADVICE: following a full submission bictegravir / emtricitabine / tenofovir alafenamide (Biktarvy ® ) is accepted for use within NHSScotland. Indication under review: Treatment of adults infected with human immunodeficiency virus 1 (HIV-1) without present or past evidence of viral resistance to the integrase inhibitor class, emtricitabine or tenofovir. Bictegravir / emtricitabine / tenofovir alafenamide was non

2018 Scottish Medicines Consortium

58. Dolutegravir rilpivirine (Juluca) - For the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults who are virologically suppressed (HIV-1 RNA copies <50 copies/mL) on a stable antiretroviral regimen

Dolutegravir rilpivirine (Juluca) - For the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults who are virologically suppressed (HIV-1 RNA copies <50 copies/mL) on a stable antiretroviral regimen Published 10 September 2018 1 dolutegravir 50mg / rilpivirine 25mg film-coated tablets (Juluca ® ) SMC2091 ViiV Healthcare Ltd. 10 August 2018 The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and advises NHS Boards and Area Drug (...) and Therapeutic Committees (ADTCs) on its use in NHS Scotland. The advice is summarised as follows: ADVICE: following a full submission dolutegravir / rilpivirine film-coated tablet (Juluca ® ) is accepted for use within NHSScotland. Indication under review: The treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults who are virologically-suppressed (HIV-1 RNA 50 copies/mL in the 6-month period before screening and no more than one instance of viral load >50 copies/mL but <200 copies/mL

2018 Scottish Medicines Consortium

59. Considerations for the clinical management of HIV elite controllers

Considerations for the clinical management of HIV elite controllers Considerations for the clinical management of HIV elite controllers | The Ontario HIV Treatment Network The Ontario HIV Treatment Network Considerations for the clinical management of HIV elite controllers Considerations for the clinical management of HIV elite controllers , , Questions What is the prevalence of elite controllers among people living with HIV? What are the specific considerations regarding diagnostic testing (...) of elite controllers? What is the recommended clinical management of elite controllers? Key take-home messages Fewer than one percent of people living with HIV are “elite controllers” (i.e. people who can spontaneously control HIV viral load without antiretroviral therapy) (1, 2). The ability of elite controllers to control their infection is likely due to genetics and a potent HIV-specific immunologic response (3–8). Elite controllers develop antibodies to HIV but have extremely low-level

2018 Ontario HIV Treatment Network

60. HIVA/BASHH guidelines on the use of HIV pre-exposure prophylaxis (PrEP)

HIVA/BASHH guidelines on the use of HIV pre-exposure prophylaxis (PrEP) Guideline writing group Michael Brady (Co-chair) Consultant in Sexual Health and HIV, King’s College Hospital, London Alison Rodger (Co-chair) Reader and Honorary Consultant Infectious Diseases and HIV, University College London David Asboe Consultant HIV and Sexual Health, Chelsea and Westminster Hospital NHS Foundation Trust, London Valentina Cambiano Lecturer in Infectious Disease Modelling and Biostatistics, University (...) College London Dan Clutterbuck Consultant HIV and Sexual Health, NHS Lothian, Monica Desai Consultant Epidemiologist, Public Health England Nigel Field Senior Lecturer, Consultant Clinical Epidemiologist, University College London Justin Harbottle Programme Officer, Terrence Higgins Trust, London Zahra Jamal Policy and Research Officer, NAZ, London Sheena McCormack Professor of Clinical Epidemiology, MRC Clinical Trials Unit at University College London Adrian Palfreeman Consultant HIV and Sexual

2018 British HIV Association