Latest & greatest articles for headache

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on headache or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on headache and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for headache

1. Acupuncture for migraine headaches

Acupuncture for migraine headaches Acupuncture for migraine headaches Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Acupuncture for migraine headaches View/ Open Date 2010-04 Format Metadata Abstract Acupuncture reduces the frequency of migraine headaches when used as an adjunct to, or in place of, medical management

2019 Clinical Inquiries

2. Atraumatic needles reduce headaches following lumbar puncture

Atraumatic needles reduce headaches following lumbar puncture Atraumatic needles reduce headaches following lumbar puncture Discover Portal Discover Portal Atraumatic needles reduce headaches following lumbar puncture Published on 17 April 2018 doi: Use of atraumatic needles rather than conventional needles for lumbar puncture more than halves the rate of post-procedure headache. Moreover, this improvement does not come at the expense of procedure success rates. Lumbar puncture involves (...) inserting a needle in the lower back into the spinal canal to collect cerebrospinal fluid for diagnosis, or to inject a treatment or anaesthetic into it. A common side effect is a headache, often from leakage of fluid from the puncture. Atraumatic needles leave a smaller puncture. After piercing the skin with an introducer needle, the atraumatic needle is inserted through the introducer. This spreads apart the fibres of the canal lining rather than cutting through it with a conventional needle

2019 NIHR Dissemination Centre

3. Paracetamol is a weak painkiller for regular tension headaches

Paracetamol is a weak painkiller for regular tension headaches Paracetamol is a weak painkiller for regular tension headaches Discover Portal Discover Portal Paracetamol is a weak painkiller for regular tension headaches Published on 13 September 2016 doi: Paracetamol is only slightly more effective than dummy tablets (placebo) at relieving pain in people who experience regular tension-type headaches. A Cochrane review found that 24 out of 100 people who took paracetamol for regular tension (...) -type headaches were pain free at two hours, compared with 19 out of 100 who took an inactive placebo. There was no difference in risk of side effects between paracetamol and placebo. Paracetamol is a cheap drug that is readily available over-the-counter. Because serious side effects are so uncommon and the “placebo effect” is so strong, this drug could be considered as an option for treating regular tension-type headache for people who find that it helps them. However, clinicians treating regular

2019 NIHR Dissemination Centre

4. A Randomized Trial of a Long-Acting Depot Corticosteroid Versus Dexamethasone to Prevent Headache Recurrence Among Patients With Acute Migraine Who Are Discharged From an Emergency Department

A Randomized Trial of a Long-Acting Depot Corticosteroid Versus Dexamethasone to Prevent Headache Recurrence Among Patients With Acute Migraine Who Are Discharged From an Emergency Department Migraine patients continue to report headache during the days and weeks after emergency department (ED) discharge. Dexamethasone is an evidence-based treatment of acute migraine that decreases the frequency of moderate or severe headache within 72 hours of ED discharge. We hypothesize that intramuscular (...) methylprednisolone acetate, a long-acting steroid that remains biologically active for 14 days, will decrease the number of days with headache during the week after ED discharge by at least 1 day compared with intramuscular dexamethasone.We conducted a randomized, blinded clinical trial comparing intravenous metoclopramide at 10 mg+intramuscular dexamethasone at 10 mg with intravenous metoclopramide at 10 mg+intramuscular methylprednisolone acetate at a dose of 160 mg for patients presenting to 2 different EDs

2019 EvidenceUpdates

5. 34m with fever, headache and myalgias

34m with fever, headache and myalgias Core IM Hoofbeats: 34M with Fever, Headache and Myalgias – Clinical Correlations Search Core IM Hoofbeats: 34M with Fever, Headache and Myalgias January 16, 2019 15 min read Podcast: | Subscribe: | By Shira Sachs MD, Stephanie Sherman MD, Cindy Fang MD and John Hwang MD || Audio Editing by Richard Chen || Graphic by Amy Ou MD Time Stamps Player three has entered the game! [0:15] Case presentation, part 1 [1:20] First impressions [3:24] Rethinking another (...) to all our listeners for all your support. Now we’re going to pass the mic to Shira and announce our early retirement. CASE PRESENTATION JOHN Yep. As part of our exit clause, I’m going to present Shira’s case. Then you’re in her capable hands. So, Shira’s patient is a previously healthy 34-year-old man presenting with resolved fever and ten days of headache and myalgias. The story he tells is that, ten days ago, he experienced 24-hours of subjective fever and chills. Subsequently, he develops severe

2019 Clinical Correlations

6. Addition of Neostigmine and Atropine to Conventional Management of Postdural Puncture Headache: A Randomized Controlled Trial

Addition of Neostigmine and Atropine to Conventional Management of Postdural Puncture Headache: A Randomized Controlled Trial Postdural puncture headache (PDPH) lacks a standard evidence-based treatment. A patient treated with neostigmine for severe PDPH prompted this study.This randomized, controlled, double-blind study compared neostigmine and atropine (n = 41) versus a saline placebo (n = 44) for treating PDPH in addition to conservative management of 85 patients with hydration

2018 EvidenceUpdates

7. gammaCore for cluster headache

gammaCore for cluster headache gammaCore for cluster headache gammaCore for cluster headache Medtech innovation briefing Published: 22 October 2018 nice.org.uk/guidance/mib162 pathways Summary Summary The technology technology described in this briefing is gammaCore. It is used as a daily preventative measure for cluster headache and can be used to treat pain during a headache. The inno innovativ vative aspects e aspects compared with other vagus nerve stimulators is that gammaCore is applied (...) to the surface of the neck rather than surgically implanted. The intended place in ther place in therap apy y would be as well as standard care, most likely where standard treatments for cluster headache are ineffective, not tolerated or contraindicated. It would be prescribed by neurologists who provide specialist headache services. The main points from the e main points from the evidence vidence summarised in this briefing are from 5 studies: 3 randomised controlled trials, 1 open-label randomised trial

2018 National Institute for Health and Clinical Excellence - Advice

8. Does Bed Rest or Fluid Supplementation Prevent Post?Dural Puncture Headache? (SRS therapy)

Does Bed Rest or Fluid Supplementation Prevent Post?Dural Puncture Headache? (SRS therapy) TAKE-HOME MESSAGE Neither bed rest nor ?uid supplementation decreases the incidence of headache after dural puncture. Does Bed Rest or Fluid Supplementation Prevent Post–Dural Puncture Headache? EBEM Commentators Michael D. April, MD, DPhil Brit Long, MD Department of Emergency Medicine San Antonio Uniformed Services Health Education Consortium Fort Sam Houston, TX Results The review included 24 trials (...) with 2,996 participants. Of these, 12 trials provided moderate- quality evidence of increased incidence of post–dural puncture headache with bed rest compared with immediate mobi- lization (RR 1.24; 95% CI 1.04 to 1.48). Furthermore, 18 trials similarly provided moderate- quality evidence that bed rest increased incidence of any head- ache compared with immediate mobilization (RR 1.16; 95% CI 1.02 to 1.32). Subgroup analyses based on indication for dural puncture, including diagnostic lumbar puncture

2018 Annals of Emergency Medicine Systematic Review Snapshots

9. Effect of resistance training on headache symptoms in adults: Secondary analysis of a RCT. (PubMed)

Effect of resistance training on headache symptoms in adults: Secondary analysis of a RCT. While strength training for the neck and shoulder muscles may be effective in reducing headache, the optimal combination of exercise frequency and duration is unknown. This study investigates the effect of different time-wise combinations of one weekly hour of strength training for the neck and shoulder muscles on headache frequency, intensity, and use of analgesics.A total of 573 office workers were (...) randomly allocated at the cluster-level to five groups; 3 × 20 min a week of minimally supervised (3MS), 1 × 60 (1WS), 3 × 20 (3WS) or 9 × 7 (9WS) min a week of supervised high-intensity strength training for 20 weeks, or to a reference group without training (REF). Headache frequency, intensity, and use of analgesics in relation to headache were determined by questionnaire at baseline and follow-up.The intention-to-treat analysis showed reduced headache frequency and intensity of approximately 50

2018 Musculoskeletal science & practice

10. Migraine headache in adults

Migraine headache in adults Migraine headache in adults - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Migraine headache in adults Last reviewed: February 2019 Last updated: October 2018 Summary Migraine is a chronic, genetically determined, episodic, neurological disorder that usually presents in early-to-mid life. Patients complain of intermittent headache and associated symptoms, such as visual disturbance (...) in general are preferred over non-specific treatments. However, there are no trials directly comparing triptans. Complications include status migrainosus, migrainous infarction, chronic migraine, persistent aura without infarction and seizures, analgesic gastropathy, transformation of episodic to chronic migraine, and medication-overuse headache. Definition Migraine is a chronic, genetically determined, episodic neurological disorder that usually presents in early-to-mid life. Key features in the history

2018 BMJ Best Practice

11. Fremanezumab for preventive treatment of migraine: Functional status on headache-free days

Fremanezumab for preventive treatment of migraine: Functional status on headache-free days To evaluate the effect of fremanezumab on the functional status on headache-free days in phase 2 episodic migraine (EM) and chronic migraine (CM) studies.Functional status data were collected prospectively via the electronic headache diary on all headache-free days by patients answering questions regarding work/school/household chore performance, speed of work completion, concentration, and feeling (...) of fatigue. Individuals with EM receiving monthly doses of fremanezumab 225 mg (n = 96) or 675 mg (n = 97) or placebo (n = 104) were compared. Individuals with CM receiving fremanezumab 675 mg followed by monthly 225 mg (n = 88) and 900 mg (n = 86) were also independently compared to those receiving placebo (n = 89).In patients with EM, compared to patients receiving placebo, those receiving fremanezumab experienced an increased number of headache-free days with normal function in work/school/household

Full Text available with Trip Pro

2018 EvidenceUpdates

12. Migraine and Tension Headache

Migraine and Tension Headache ? 2018 Kaiser Foundation Health Plan of Washington. All rights reserved. 1 Migraine and Tension Headache Guideline Background 2 Diagnosis Red flag warning signs 2 Differential diagnosis 2 Imaging 3 Migraine versus tension headache 3 Medication overuse headache 3 Menstruation-related migraine 3 Tension Headache Acute treatment 4 Prophylaxis 5 Migraine Headache Acute treatment 6 Treatment of refractory migraine 7 Prophylaxis 8 Menstruation-related migraine (...) prophylaxis 11 Medication Overuse Headache Treatment 12 Evidence Summary 13 References 18 Clinician Lead and Guideline Development 21 Last guideline approval: April 2018 Guidelines are systematically developed statements to assist patients and providers in choosing appropriate health care for specific clinical conditions. While guidelines are useful aids to assist providers in determining appropriate practices for many patients with specific clinical problems or prevention issues, guidelines are not meant

2018 Kaiser Permanente Clinical Guidelines

13. Headache

Headache Top results for headache - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4 (...) ) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for headache The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted

2018 Trip Latest and Greatest

14. Headache

Headache Evidence Maps - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4

2018 Trip Evidence Maps

15. Melatonin for preventing primary headache: A systematic review

Melatonin for preventing primary headache: A systematic review The aim of this study was to assess the effectiveness and safety of melatonin for primary headache.This systematic review following the Cochrane Handbook for Systematic Reviews of Interventions recommendations and PRISMA Statement.Four randomized controlled trials were included (351 participants). According to the GRADE approach the quality of evidence was very low. The use of melatonin for migraine showed that (i) reduced (...) the number of days with pain and the analgesic consumption when compared with placebo, (ii) no benefits on headache intensity, number of headache days and analgesics consumption when compared with amitriptyline, (iii) reduced the number of analgesic consumption, the attack frequency and the headache intensity when associated with propranolol plus nortriptyline vs placebo plus propranolol plus nortriptyline, and (iv) no difference for any of the interest outcomes when associated with propranolol plus

2018 EvidenceUpdates

16. The Impact of Spinal Needle Selection on Postdural Puncture Headache: A Meta-Analysis and Metaregression of Randomized Studies

The Impact of Spinal Needle Selection on Postdural Puncture Headache: A Meta-Analysis and Metaregression of Randomized Studies Potentially broadened indications for spinal anesthesia require increased understanding of the risk factors and prevention measures associated with postdural puncture headache (PDPH). This review is designed to examine the association between spinal needle characteristics and incidence of PDPH.Meta-analysis and metaregression was performed on randomized controlled

2018 EvidenceUpdates

17. Effect of Head and Neck Immobilization on Postspinal Headache: A Randomized Controlled Trial. (PubMed)

Effect of Head and Neck Immobilization on Postspinal Headache: A Randomized Controlled Trial. The purpose of the study was to determine the effect of head and neck immobilization on postdural puncture headache (PDPH) through the use of cervical collars.This was a fully randomized controlled trial.The sample group of the study consisted of 120 patients. Patients in the experimental group were followed up by using the appropriate cervical collar after the operation. The cervical collar was kept (...) on until mobilization. Follow-ups of patients in the control group continued without limiting head and neck movements. Headaches of patients in the experimental and control groups at 24, 48, and 72 hours after the operation were determined.The average age of the patients in the experimental group was 22.70 ± 2.72, whereas it was 22.93 ± 3.29 in the control group. The mean body mass index of the experimental group and control group was 24.24 ± 2.62 and 23.46 ± 3.03, respectively. The mean scores

2018 Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses

18. Paracetamol is a weak painkiller for regular tension headaches

Paracetamol is a weak painkiller for regular tension headaches Paracetamol is a weak painkiller for regular tension headaches Discover Portal Discover Portal Paracetamol is a weak painkiller for regular tension headaches Published on 13 September 2016 doi: Paracetamol is only slightly more effective than dummy tablets (placebo) at relieving pain in people who experience regular tension-type headaches. A Cochrane review found that 24 out of 100 people who took paracetamol for regular tension (...) -type headaches were pain free at two hours, compared with 19 out of 100 who took an inactive placebo. There was no difference in risk of side effects between paracetamol and placebo. Paracetamol is a cheap drug that is readily available over-the-counter. Because serious side effects are so uncommon and the “placebo effect” is so strong, this drug could be considered as an option for treating regular tension-type headache for people who find that it helps them. However, clinicians treating regular

2018 NIHR Dissemination Centre

19. Aminophylline for treatment of postdural puncture headache: A randomized clinical trial

Aminophylline for treatment of postdural puncture headache: A randomized clinical trial To investigate the efficacy and safety of IV aminophylline for patients with postdural puncture headache (PDPH).We randomly assigned patients to groups receiving either 250 mg IV aminophylline or a placebo within 3 hours of symptom onset once daily for 2 consecutive days. The primary endpoint was headache severity 8 hours after treatment. We assessed this using visual analog scale (VAS) scores taken from (...) with PDPH, IV aminophylline reduces headache severity.© 2018 American Academy of Neurology.

2018 EvidenceUpdates

20. Dose-response and efficacy of spinal manipulation for care of cervicogenic headache: a dual-center randomized controlled trial

Dose-response and efficacy of spinal manipulation for care of cervicogenic headache: a dual-center randomized controlled trial The optimal number of visits for the care of cervicogenic headache (CGH) with spinal manipulative therapy (SMT) is unknown.The present study aimed to identify the dose-response relationship between visits for SMT and chronic CGH outcomes and to evaluate the efficacy of SMT by comparison with a light-massage control.This is a two-site, open-label randomized controlled (...) ); a maximal effective dose could not be determined. Cervicogenic headache days/4 weeks were reduced from about 16 to 8 for the highest and most effective dose of 18 SMT visits. Mean differences in CGH days/4 weeks between 18 SMT visits and control were -3.3 (p=.004) and -2.9 (p=.017) at the primary end points, and were similar in magnitude at the remaining end points (p<.05). Differences between other SMT doses and control were smaller in magnitude (p>.05). Cervicogenic headache intensity showed

2018 EvidenceUpdates