Interventions for preventing gestational diabetes mellitus: A systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

Treating mild gestational diabetes mellitus: a cost-effectiveness analysis Treating mild gestational diabetes mellitus: a cost-effectiveness analysis Treating mild gestational diabetes mellitus: a cost-effectiveness analysis Ohno MS, Sparks TN, Cheng YW, Caughey AB Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical (...) assessment on the reliability of the study and the conclusions drawn. CRD summary The objective was to assess the cost-effectiveness of treatment for mild gestational diabetes mellitus, from a societal perspective. The authors concluded that treatment for mild gestational diabetes improved both maternal and neonatal outcomes and was cost-effective. The cost-effectiveness framework was valid and the authors’ conclusions appear to be robust, but more detail on the data sources would have been useful. Type

Effects of a single post-partum injection of a high dose of vitamin D on glucose tolerance and insulin resistance in mothers with first-time gestational diabetes mellitus This study was performed to determine the effect of a single, large, intramuscular injection of vitamin D post-partum on glucose tolerance and insulin resistance in women with gestational diabetes.Forty-five participants in a randomized controlled trial on gestational diabetes mellitus were divided into an intervention group (...) -intervention, the median C-peptide decreased in the intervention group and increased in the control group, but the change was significant only in the control group (P = 0.03).A single injection of 300,000 IU of vitamin D3 achieves a 3-month serum 25-hydroxyvitamin D range of 50-80 nmol/l and is an efficient, effective and safe procedure for improving the vitamin status and indices of insulin resistance in mothers with gestational diabetes after delivery.© 2011 The Authors. Diabetic Medicine © 2011 Diabetes

Diabetes in Pregnancy and Gestational Diabetes Mellitus (GDM); Antidepressants in Pregnancy and Lactation RxFiles Q&A Summary www.RxFiles.ca - April 2012 Lynette Kosar BSP, MSc Are Antidepressants Safe during Pregnancy & Breastfeeding? Up to ~25% of pregnant women will suffer from depression while pregnant. 1 The decision on how to treat depression and/or anxiety during & after pregnancy requires careful consideration of benefits and harms & collaborative discussions with the patient. SHOULD (...) and/or use other substances), and are less likely to take prenatal vitamins. ? There is a higher risk of spontaneous abortions, miscarriages, gestational hypertension, preeclampsia, preterm deliveries, low birth weight, small for gestational age, cesarean section, low Apgar scores, need for neonatal intensive care & ? length of hospital stay. - Some antidepressant studies have found these same risks, but most were unable to control for underlying depression. 1 ? Postpartum depression can impact

Effectiveness of gestational diabetes treatment: a systematic review with quality of evidence assessment Effectiveness of gestational diabetes treatment: a systematic review with quality of evidence assessment Effectiveness of gestational diabetes treatment: a systematic review with quality of evidence assessment Falavigna M, Schmidt MI, Trujillo J, Alves LF, Wendland ER, Torloni MR, Colagiuri S, Duncan BB CRD summary This review concluded that gestational diabetes treatment compared to usual (...) antenatal care effectively reduced large for gestational age at birth, macrosomia, shoulder dystocia, pre-eclampsia and hypertensive disorders without compromising safety. The authors' conclusions reflect the evidence but the evidence base was small for some outcomes and the potential risk of bias in the included studies limits the reliability of the findings. Authors' objectives To assess the effectiveness of gestational diabetes treatment compared to usual antenatal care in the prevention of adverse

Glucose challenge test for detecting gestational diabetes mellitus: a systematic review Glucose challenge test for detecting gestational diabetes mellitus: a systematic review Glucose challenge test for detecting gestational diabetes mellitus: a systematic review van Leeuwen M, Louwerse MD, Opmeer BC, Limpens J, Serlie MJ, Reitsma JB, Mol BW CRD summary The authors concluded that higher accuracy measures were needed for the 50g glucose challenge test to be used as a definite diagnostic test (...) in place of the oral glucose tolerance test. This was a well-conducted review but limitations in the evidence available and potential for missing unpublished studies make the reliability and generalisability of the pooled results uncertain. Authors' objectives To determine the diagnostic accuracy of the 50g glucose challenge test for gestational diabetes mellitus. Searching MEDLINE and EMBASE were searched without methodological filter or other restrictions up to October 2010. Search terms were

Gestational diabetes screening with the new IADPSG guidelines: a cost-effectiveness analysis Gestational diabetes screening with the new IADPSG guidelines: a cost-effectiveness analysis Gestational diabetes screening with the new IADPSG guidelines: a cost-effectiveness analysis Mission JF, Ohno MS, Cheng YW, Caughey AB Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods (...) , the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The study examined the cost-effectiveness of routine screening with the two-hour oral glucose tolerance test (OGTT) versus the one-hour glucose challenge test for gestational diabetes mellitus screening following new International Association of Diabetes in Pregnancy Study Group guidelines. The study used a valid cost-effectiveness framework and considered various

Randomised controlled trial: Metformin is not significantly different from insulin for preventing fetal macrosomia in women with gestational diabetes Metformin is not significantly different from insulin for preventing fetal macrosomia in women with gestational diabetes | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies (...) diabetes Article Text Therapeutics Randomised controlled trial Metformin is not significantly different from insulin for preventing fetal macrosomia in women with gestational diabetes Steve L Hyer Statistics from Altmetric.com Commentary on: Ijäs H , Vääräsmäki M , Morin-Papunen L , et al . Metformin should be considered in the treatment of gestational diabetes: a prospective randomised study. Context Evidence is accumulating that metformin is a safe alternative to insulin for the treatment

Screening and Diagnosing Gestational Diabetes Mellitus Screening and Diagnosing Gestational Diabetes Mellitus | Effective Health Care Program Search Effective Health Care website Submit search Toggle navigation Select site to search Search Effective Health Care website Submit search Screening and Diagnosing Gestational Diabetes Mellitus Nov. 5, 2012 Systematic Review Mar. 4, 2013 Disposition of Comments Report Screening and Diagnosing Gestational Diabetes Mellitus Systematic Review Archived (...) November 5, 2012 2.9 MB Related Files Archived : This report is greater than 3 years old. Findings may be used for research purposes, but should not be considered current. People using assistive technology may not be able to fully access information in these files. For additional assistance, please . Structured Abstract Background There is uncertainty as to the optimal approach for screening and diagnosis of gestational diabetes mellitus (GDM). Based on systematic reviews published in 2003 and 2008

Pre-pregnancy care for women with pre-gestational diabetes mellitus: a systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

Impact of maternal diabetes mellitus on mortality and morbidity of preterm infants (24-33 weeks` gestation) We hypothesized that maternal diabetes mellitus (DM) increases the risk for mortality, respiratory distress syndrome (RDS), and major complications of prematurity.Analysis of prospectively collected (1995-2007) Israel National Very Low Birth Weight Infant Database. Maternal DM was recorded as pregestational or gestational. Multivariable logistic regression analysis was used to assess (...) the independent effect of maternal DM status on infant mortality, RDS, and other complications of prematurity.Infants of mothers with pregestational (n = 120) and gestational (n = 825) DM were similar, and their data were pooled for analyses. Mothers with DM were more likely to have received a complete course of prenatal steroids than control mothers. Infants of diabetic mothers (IDM) had a slightly higher gestational age and birthweight than non-IDM's. Distribution of birthweight percentiles and the mean

Comparison of hemoglobin A1c with fasting plasma glucose and 2-h postchallenge glucose for risk stratification among women with recent gestational diabetes mellitus Postpartum testing with a 75-g 2-h oral glucose tolerance test or fasting plasma glucose (FPG) alone is often not performed among women with histories of gestational diabetes mellitus (GDM). Use of hemoglobin A(1c) (A1C) might increase testing. The association between A1C and glucose has not been examined in women with histories

Screening for gestational diabetes mellitus: cost-utility of different screening strategies based on a woman's individual risk of disease Screening for gestational diabetes mellitus: cost-utility of different screening strategies based on a woman's individual risk of disease Screening for gestational diabetes mellitus: cost-utility of different screening strategies based on a woman's individual risk of disease Round JA, Jacklin P, Fraser RB, Hughes RG, Mugglestone MA, Holt RI Record Status (...) This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The objective was to assess the cost-effectiveness of eight screening strategies for gestational diabetes. The authors concluded that some form of screening was usually cost-effective, but the best strategy varied

The effect of myoinositol supplementation on insulin resistance in patients with gestational diabetes To test the hypothesis that myoinositol supplementation will improve insulin sensitivity as measured by markers of insulin resistance such as homeostasis model assessment of insulin resistance and adiponectin in women with gestational diabetes.The trial was carried out in diet-treated patients with gestational diabetes diagnosed in our department between April 2008 and September 2009. Subjects (...) . Fasting glucose and insulin, and consequently homeostasis model assessment of insulin resistance, decreased in both groups (50% in the study group vs. 29% in the control group), but the decline in the study group was significantly greater than that in the control group (P = 0.0001). Adiponectin increased in the myoinositol group while it decreased in the control group (P = 0.009).Myoinositol improves insulin resistance in patients with gestational diabetes.© 2011 The Authors. Diabetic Medicine © 2011

Accuracy of the random glucose test as screening test for gestational diabetes mellitus: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

Metformin should be considered in the treatment of gestational diabetes: a prospective randomised study To examine if oral metformin is as effective as insulin in the prevention of fetal macrosomy in pregnancies complicated with gestational diabetes mellitus (GDM).Open-label prospective randomised controlled study.Maternity outpatient clinics in a secondary and tertiary level hospital in Finland.One hundred women with GDM who did not attain euglycaemia with diet.Women were randomised to therapy (...) with insulin (n = 50) or oral metformin (n = 50).Incidence of large-for-gestational-age (LGA) infants and neonatal morbidity.There were no statistically significant differences in the incidence of LGA (8.5 versus 10.0%, P = 0.97), mean birthweight, mean cord artery pH or neonatal morbidity between the insulin and metformin groups. Fifteen (31.9%) of the 47 women randomised to metformin needed supplemental insulin. They were more obese (with a body mass index of 36 versus 30 kg/m(2), P = 0.002), had higher

Gestational Diabetes - Whom Do We Treat?

Diagnosis and Treatment of Gestational Diabetes Diagnosis and Treatment of Gestational Diabetes Scientific Impact Paper No. 23 January 2011Diagnosis and Treatment of Gestational Diabetes 1. Background Historically, there has been controversy over screening and diagnosis of gestational diabetes. The 2002 National Institute for Health and Clinical Excellence (NICE) Health Technology Assessment concluded that there was insufficient evidence to advocate universal screening in pregnancy while noting (...) women. The results of this large observational study formed the basis of a reconsideration of diagnosis and screening for diabetes in a consensus report published in 2010 4 under the auspices of the International Association of Diabetes and Pregnancy Study Groups (IADPSG). A further major trial examining the effect on pregnancy outcomes of management of gestational diabetes was reported in 2009, 5 while a randomised controlled trial in 2008 examined the efficacy of metformin, 6 adding to the older

Development of a model to assess the cost-effectiveness of gestational diabetes mellitus screening and lifestyle change for the prevention of type 2 diabetes mellitus Development of a model to assess the cost-effectiveness of gestational diabetes mellitus screening and lifestyle change for the prevention of type 2 diabetes mellitus Development of a model to assess the cost-effectiveness of gestational diabetes mellitus screening and lifestyle change for the prevention of type 2 diabetes (...) mellitus Lohse N, Marseille E, Kahn JG Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The study examined the cost-effectiveness of gestational diabetes mellitus screening and management using a mathematical model (GDModel). The authors

Resistance exercise and glycemic control in women with gestational diabetes mellitus The objective of the study was to evaluate the effect of a resistance exercise program with an elastic band on insulin requirement and glycemic control in patients with gestational diabetes mellitus (GDM).Sixty-four patients with gestational diabetes mellitus were randomly assigned into 2 groups: an exercise group (EG; n = 32) and a control group not submitted to the exercise program (CG; n = 32).A significant