Latest & greatest articles for gestational diabetes

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Top results for gestational diabetes

41. Immediate delivery or expectant management in gestational diabetes at term: the GINEXMAL randomised controlled trial Full Text available with Trip Pro

Immediate delivery or expectant management in gestational diabetes at term: the GINEXMAL randomised controlled trial To evaluate maternal and perinatal outcomes after induction of labour versus expectant management in pregnant women with gestational diabetes at term.Multicentre open-label randomised controlled trial.Eight teaching hospitals in Italy, Slovenia, and Israel.Singleton pregnancy, diagnosed with gestational diabetes by the International Association of Diabetes and Pregnancy Study (...) diabetes, without other maternal or fetal conditions, no difference was detected in birth outcomes regardless of the approach used (i.e. active versus expectant management). Although the study was underpowered, the magnitude of the between-group difference was very small and without clinical relevance.Immediate delivery or expectant management in gestational diabetes at term?© 2016 Royal College of Obstetricians and Gynaecologists.

2016 EvidenceUpdates

42. Regular Exercise to Prevent the Recurrence of Gestational Diabetes Mellitus: A Randomized Controlled Trial Full Text available with Trip Pro

Regular Exercise to Prevent the Recurrence of Gestational Diabetes Mellitus: A Randomized Controlled Trial To investigate the effect of a supervised home-based exercise program on the recurrence and severity of gestational diabetes mellitus (GDM) together with other aspects of maternal health and obstetric and neonatal outcomes.This randomized controlled trial allocated women with a history of GDM to an exercise intervention (14-week supervised home-based stationary cycling program (...) ) or to a control group (standard care) at 13±1 weeks of gestation. The primary outcome was a diagnosis of GDM. Secondary outcomes included maternal fitness, psychological well-being, and obstetric and neonatal outcomes. A sample size of 180 (90 in each group) was required to attain 80% power to detect a 40% reduction in the incidence of GDM.Between June 2011 and July 2014, 205 women provided written consent and completed baseline assessments. Of these, 33 (16%) were subsequently excluded as a result

2016 EvidenceUpdates

43. Dietary supplementation with myo-inositol in women during pregnancy for treating gestational diabetes. Full Text available with Trip Pro

Dietary supplementation with myo-inositol in women during pregnancy for treating gestational diabetes. Gestational diabetes mellitus (GDM) is any degree of glucose intolerance that first presents and is recognised during pregnancy and usually resolves after the birth of the baby. GDM is associated with increased short- and long-term morbidity for the mother and her baby. Treatment usually includes lifestyle modification and/or pharmacological therapy (oral antidiabetic agents or insulin (...) of myo-inositol for the treatment of gestational diabetes, with no data to examine the majority of outcomes in this review. There do not appear to be any benefits for the infant associated with exposure to myo-inositol such as reduced risk of being born large-for-gestational age. Although the risk of neonatal hypoglycaemia is reduced for the myo-inositol group, there is evidence of imprecision. Evidence from two studies suggested that myo-inositol was associated with a reduced change in maternal BMI

2016 Cochrane Controlled trial quality: predicted high

44. Risk perception and unrecognized type 2 diabetes in women with previous gestational diabetes mellitus. Full Text available with Trip Pro

Risk perception and unrecognized type 2 diabetes in women with previous gestational diabetes mellitus. Women with a history of gestational diabetes mellitus (GDM) have a high chance of developing type 2 diabetes mellitus (T2DM) following the index pregnancy, however, little is known of women's perception of this risk. The objectives were to (1) determine women's perception of risk of future development of T2DM following a GDM pregnancy and (2) describe the prevalence of undetected dysglycaemia (...) in a Canadian population. The study was designed as a 9-11 year follow-up study of women previously enrolled in a randomized controlled trial of tight versus minimal intervention for GDM. Women's perception of future risk of diabetes was determined by questionnaire. Fasting lipid profile, height and weight were performed on all participants. Oral glucose tolerance tests were performed on all women without prior history of diabetes mellitus type 2 (DM2). The study was conducted at Ottawa Hospital General

2016 Obstetric medicine Controlled trial quality: uncertain

45. External validation of prognostic models to predict risk of gestational diabetes mellitus in one Dutch cohort: prospective multicentre cohort study. Full Text available with Trip Pro

External validation of prognostic models to predict risk of gestational diabetes mellitus in one Dutch cohort: prospective multicentre cohort study.  To perform an external validation and direct comparison of published prognostic models for early prediction of the risk of gestational diabetes mellitus, including predictors applicable in the first trimester of pregnancy. External validation of all published prognostic models in large scale, prospective, multicentre cohort study. 31 independent (...) midwifery practices and six hospitals in the Netherlands. Women recruited in their first trimester (<14 weeks) of pregnancy between December 2012 and January 2014, at their initial prenatal visit. Women with pre-existing diabetes mellitus of any type were excluded. Discrimination of the prognostic models was assessed by the C statistic, and calibration assessed by calibration plots. 3723 women were included for analysis, of whom 181 (4.9%) developed gestational diabetes mellitus in pregnancy. 12

2016 BMJ

46. Lactation and Progression to Type 2 Diabetes Mellitus After Gestational Diabetes Mellitus Full Text available with Trip Pro

Lactation and Progression to Type 2 Diabetes Mellitus After Gestational Diabetes Mellitus 27538169 2017 12 07 2018 12 02 1539-3704 165 4 2016 08 16 Annals of internal medicine Ann. Intern. Med. Lactation and Progression to Type 2 Diabetes Mellitus After Gestational Diabetes Mellitus. 299-300 10.7326/L16-0106 Gunderson Erica P EP Study of Women, Infant Feeding and Type 2 Diabetes After GDM Pregnancy Investigators eng R01 HD050625 HD NICHD NIH HHS United States Journal Article Comment United (...) States Ann Intern Med 0372351 0003-4819 AIM IM Ann Intern Med. 2015 Dec 15;163(12):889-98 26595611 Ann Intern Med. 2016 Aug 16;165(4):299 27538168 Breast Feeding Diabetes Mellitus, Type 2 Diabetes, Gestational Disease Progression Female Humans Lactation Pregnancy 2016 8 19 6 0 2016 8 19 6 0 2017 12 8 6 0 ppublish 27538169 2544588 10.7326/L16-0106 PMC5613933 NIHMS906750 Am J Psychiatry. 2001 Jun;158(6):848-56 11384888 Matern Child Health J. 2009 May;13(3):334-42 18473131 BMC Public Health. 2011 Dec

2016 Annals of Internal Medicine

47. Heterogeneous Contribution of Insulin Sensitivity and Secretion Defects to Gestational Diabetes Mellitus Full Text available with Trip Pro

Heterogeneous Contribution of Insulin Sensitivity and Secretion Defects to Gestational Diabetes Mellitus To characterize physiologic subtypes of gestational diabetes mellitus (GDM).Insulin sensitivity and secretion were estimated in 809 women at 24-30 weeks' gestation, using oral glucose tolerance test-based indices. In women with GDM (8.3%), defects in insulin sensitivity or secretion were defined below the 25th percentile in women with normal glucose tolerance (NGT). GDM subtypes were defined (...) outcomes similar to those in women with NGT.Heterogeneity of physiologic processes underlying hyperglycemia exists among women with GDM. GDM with impaired insulin sensitivity confers a greater risk of adverse outcomes.© 2016 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

2016 EvidenceUpdates

48. Different intensities of glycaemic control for women with gestational diabetes mellitus. Full Text available with Trip Pro

Different intensities of glycaemic control for women with gestational diabetes mellitus. Gestational diabetes mellitus (GDM) has major short- and long-term implications for both the mother and her baby. GDM is defined as a carbohydrate intolerance resulting in hyperglycaemia or any degree of glucose intolerance with onset or first recognition during pregnancy from 24 weeks' gestation onwards and which resolves following the birth of the baby. Rates for GDM can be as high as 25% depending (...) diagnosed with GDM. Data from 171 of the 180 women were published as a conference abstract and no full report has been identified. The overall risk of bias of the single included study was judged to be unclear.The included trial did not report on any of this review's primary outcomes. For the mother, these were hypertension disorders of pregnancy or subsequent development of type 2 diabetes. For the infant, our primary outcomes were (perinatal (fetal and neonatal) mortality; large-for-gestational age

2016 Cochrane

49. Short-term risk of cancer among women with previous gestational diabetes: a population-based study (Abstract)

Short-term risk of cancer among women with previous gestational diabetes: a population-based study To evaluate the relationship between gestational diabetes (GDM) and incidence of cancer in women within the first decade postpartum.This population-based retrospective cohort study compared the risk of cancer in women with GDM with that of a matched control group comprising pregnant women without diabetes. We included women from Ontario, Canada aged 20-50 years with no history of cancer who had (...) given birth between 1995 and 2008 (N = 149 049). Women with GDM (N = 49 684) were matched on age and year of giving birth, in a ratio of 1:2, to pregnant women without diabetes (N = 99 365).Over a median 8-year follow-up, there were a total of 2927 (1.5%) cancers. After adjustment for covariates, we found no significant difference in overall risk of cancer between women with GDM and matched control subjects; however, GDM was associated with a significantly greater risk of thyroid cancer (adjusted

2016 EvidenceUpdates

50. Pre-pregnancy potato consumption and risk of gestational diabetes mellitus: prospective cohort study. Full Text available with Trip Pro

Pre-pregnancy potato consumption and risk of gestational diabetes mellitus: prospective cohort study. What is the association between potato consumption before pregnancy and the risk of gestational diabetes mellitus (GDM)?This prospective cohort study included 15,632 women from the Nurses' Health Study II (1991-2001). They had no previous GDM or chronic diseases before pregnancy. Consumption of potatoes and other foods was assessed every four years. Incident first time GDM was ascertained from (...) % lower risk of GDM. Consumption and diabetes were self reported, and severity of diabetes was unknown. More than 90% of women were white. A causal association cannot be assumed.Higher levels of potato consumption before pregnancy are associated with greater risk of GDM, and substitution of potatoes with other vegetables, legumes, or whole grain foods might lower the risk.Funding was received from the Intramural Research Program of the Eunice Kennedy Shriver National Institute of Child Health

2016 BMJ

51. The Comparative Effectiveness of Diabetes Prevention Strategies to Reduce Postpartum Weight Retention in Women With Gestational Diabetes Mellitus: The Gestational Diabetes' Effects on Moms (GEM) Cluster Randomized Controlled Trial Full Text available with Trip Pro

The Comparative Effectiveness of Diabetes Prevention Strategies to Reduce Postpartum Weight Retention in Women With Gestational Diabetes Mellitus: The Gestational Diabetes' Effects on Moms (GEM) Cluster Randomized Controlled Trial To compare the effectiveness of diabetes prevention strategies addressing postpartum weight retention for women with gestational diabetes mellitus (GDM) delivered at the health system level: mailed recommendations (usual care) versus usual care plus a Diabetes (...) Prevention Program (DPP)-derived lifestyle intervention.This study was a cluster randomized controlled trial of 44 medical facilities (including 2,280 women with GDM) randomized to intervention or usual care. The intervention included mailed gestational weight gain recommendations plus 13 telephone sessions between 6 weeks and 6 months postpartum. Primary outcomes included the following: proportion meeting the postpartum goals of 1) reaching pregravid weight if pregravid BMI <25.0 kg/m(2) or 2) losing 5

2016 EvidenceUpdates Controlled trial quality: uncertain

53. Randomized clinical trial: Detemir is non-inferior to NPH insulin in women with pregestational type 2 diabetes and gestational diabetes mellitus

Randomized clinical trial: Detemir is non-inferior to NPH insulin in women with pregestational type 2 diabetes and gestational diabetes mellitus Detemir is non-inferior to NPH insulin in women with pregestational type 2 diabetes and gestational diabetes mellitus | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see (...) our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Detemir is non-inferior to NPH insulin in women with pregestational type 2 diabetes and gestational diabetes mellitus Article

2016 Evidence-Based Medicine

54. Large-for-Gestational-Age Ultrasound Diagnosis and Risk for Cesarean Delivery in Women With Gestational Diabetes Mellitus (Abstract)

Large-for-Gestational-Age Ultrasound Diagnosis and Risk for Cesarean Delivery in Women With Gestational Diabetes Mellitus To assess the accuracy of a large-for-gestational-age (LGA) ultrasound diagnosis and the subsequent risk for cesarean delivery associated with ultrasound diagnosis of LGA among women with gestational diabetes mellitus.This was a retrospective cohort study of 903 women with GDM who delivered after 36 weeks of gestation with an ultrasound-estimated fetal weight within 31 days (...) delivery (adjusted odds ratio [OR] 3.13, 95% confidence interval [CI] 2.10-4.67, P<.001) after adjusting for relevant covariates. Stratified analyses demonstrated that ultrasound diagnosis of LGA was associated with an increased risk for cesarean delivery whether the birth weight was between 2,500 and 3,499 g (OR 2.82, 95% CI 1.62-4.84, P<.001) or between 3,500 and 4,500 g (OR 3.47, 95% CI 2.06-5.88, P<.001).Ultrasonography significantly overestimates the prevalence of LGA in women with gestational

2015 EvidenceUpdates

55. Lifestyle intervention for gestational diabetes mellitus prevention: A cluster-randomized controlled study Full Text available with Trip Pro

Lifestyle intervention for gestational diabetes mellitus prevention: A cluster-randomized controlled study The study was to examine whether gestational diabetes mellitus (GDM) can be prevented by early trimester lifestyle counseling in a high-risk population.From September 2012 to January 2013, 1664 pregnancies in the Department of Obstetrics and Gynecology of First Hospital of Peking University were enrolled in the study during their first prenatal care visit before the 8 gestational weeks (...) on maternal anthropometrics were offered. Both groups were followed until 75 g oral glucose tolerance test (OGTT) testing at 24-28 gestational weeks. The weight gain after intervention and the prevalence of GDM were used to evaluate the effect.(1) According to the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria, the positive rate of GDM for the intervention group was 17.16% (23/134), lower than the control group which was 23.91% (33/138), P = 0.168. (2) The weight gain

2015 Chronic diseases and translational medicine Controlled trial quality: uncertain

56. Gestational Diabetes Mellitus Can Be Prevented by Lifestyle Intervention: The Finnish Gestational Diabetes Prevention Study (RADIEL): A Randomized Controlled Trial Full Text available with Trip Pro

Gestational Diabetes Mellitus Can Be Prevented by Lifestyle Intervention: The Finnish Gestational Diabetes Prevention Study (RADIEL): A Randomized Controlled Trial To assess whether gestational diabetes mellitus (GDM) can be prevented by a moderate lifestyle intervention in pregnant women who are at high risk for the disease.Two hundred ninety-three women with a history of GDM and/or a prepregnancy BMI of ≥30 kg/m(2) were enrolled in the study at <20 weeks of gestation and were randomly (...) % in the intervention group and 21.6% in the control group ([95% CI 0.40-0.98%]; P = 0.044, after adjustment for age, prepregnancy BMI, previous GDM status, and the number of weeks of gestation). Gestational weight gain was lower in the intervention group (-0.58 kg [95% CI -1.12 to -0.04 kg]; adjusted P = 0.037). Women in the intervention group increased their leisure time physical activity more and improved their dietary quality compared with women in the control group.A moderate individualized lifestyle

2015 EvidenceUpdates Controlled trial quality: uncertain

57. Systematic review with meta analysis: In women with gestational diabetes requiring drug treatment, glibenclamide may be inferior to insulin and metformin: metformin (plus insulin when required) performs better than insulin

Systematic review with meta analysis: In women with gestational diabetes requiring drug treatment, glibenclamide may be inferior to insulin and metformin: metformin (plus insulin when required) performs better than insulin In women with gestational diabetes requiring drug treatment, glibenclamide may be inferior to insulin and metformin: metformin (plus insulin when required) performs better than insulin | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our (...) or password? You are here In women with gestational diabetes requiring drug treatment, glibenclamide may be inferior to insulin and metformin: metformin (plus insulin when required) performs better than insulin Article Text Therapeutics/Prevention Systematic review with meta analysis In women with gestational diabetes requiring drug treatment, glibenclamide may be inferior to insulin and metformin: metformin (plus insulin when required) performs better than insulin Dana Carroll , Kristi W Kelley

2015 Evidence-Based Medicine

58. Guideline Supplement: Gestational diabetes mellitus

Guideline Supplement: Gestational diabetes mellitus Maternity and Neonatal C linical G uideline Department of Health Supplement: Gestational diabetes mellitus Queensland Clinical Guideline Supplement: Gestational diabetes mellitus Refer to online version, destroy printed copies after use Page 2 of 12 Table of Contents 1 Introduction 3 1.1 Funding 3 1.2 Conflict of interest 3 1.3 Guideline review 3 2 Methodology 4 2.1 Topic identification 4 2.2 Scope 4 2.3 Clinical questions 4 2.4 Exclusions 4 (...) ) 3234 1479. Queensland Clinical Guideline Supplement: Gestational diabetes mellitus Refer to online version, destroy printed copies after use Page 3 of 12 1 Introduction This document is a supplement to the Queensland Clinical Guideline Gestational diabetes mellitus (GDM). It provides supplementary information regarding guideline development, makes summary recommendations, suggests measures to assist implementation and quality activities and summarises changes (if any) to the guideline since

2015 Queensland Health

59. Flowchart: Gestational diabetes mellitus postpartum care

Flowchart: Gestational diabetes mellitus postpartum care Document Number: F15.33-3-V1-R20 Department of Health Queensland Clinical Guidelines State of Queensland (Queensland Health) 2015 http://creativecommons.org/licenses/by-nc-nd/3.0/au/deed.en Queensland Clinical Guidelines, Guidelines@health.qld.gov.au Postpartum care for all GDM Cease Metformin and/or Insulin immediately after birth (vaginal or CS) BGL monitoring • Target BGL = 7.0 mmol/L • Monitor BGL QID for 24 hours (preprandial (...) and before bed) • If all preprandial BGL between 4-7 mmol/L, cease monitoring 24 hours after birth BGL 7.0 mmol/L • If any preprandial BGL > 7.0 mmol/L o Seek medical review o Continue BGL monitoring • Insulin rarely required postpartum o If indicated, prescribe lower dose than required during pregnancy IV therapy (if any) • If BGL = 4.0 mmol/L and diet tolerated cease mainline IV fluids after birth All GDM Pharmacological therapy? Insulin or Metformin Queensland Clinical Guideline: Gestational diabetes

2015 Queensland Health

60. Flowchart: Intrapartum management for gestational diabetes mellitus requiring Insulin and/or Metformin

Flowchart: Intrapartum management for gestational diabetes mellitus requiring Insulin and/or Metformin Document Number: F15.33--2-V1-R20 Department of Health Queensland Clinical Guidelines State of Queensland (Queensland Health) 2015 http://creativecommons.org/licenses/by-nc-nd/3.0/au/deed.en Queensland Clinical Guidelines, Guidelines@health.qld.gov.au Intrapartum management for GDM requiring Insulin and/or Metformin Metformin • Cease when labour established Insulin • Cease when labour

2015 Queensland Health