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at increased risk of opioid use 1 year after injury). Downward arrows are accompanied by text (in parentheses) that indicates the factor that is at decreased risk for the outcome, in keeping with the direction of the arrow (e.g., people in olderage categories at decreased risk of long-term opioid use). In the Comorbidity column, dementia is also highlighted since it frequently, but not universally, was associated with decreased risk, in contrast with other comorbidities. Across heat map tables (...) age (=65, at various thresholds vs. 60-64; Table 7), college education (Table 8), and opioid misuse (recreational use; Table 9). Increased associations were also found for women (Table 7) and people with less social connectedness (Table 8). No 33 statistically significant associations were found for quality of life (Table 7) or tobacco use (Table 9). Summary of Factors Associated With Opioid-Related Disorders Six studies have evaluated factors associated with opioid-related disorders among older
. doi: 10.1001/jamanetworkopen.2020.17688. Association of Dance-Based Mind-Motor Activities With Falls and Physical Function Among Healthy Older Adults: A Systematic Review and Meta-analysis , , , , , , , , , , Affiliations Expand Affiliations 1 Department of Geriatrics and Aging Research, University Hospital Zurich and University of Zurich, Zurich, Switzerland. 2 Center on Aging and Mobility, University of Zurich, Zurich, Switzerland. 3 University Department of Geriatric Medicine Felix Platter (...) search included the PubMed, Embase, Cochrane Library, Web of Science, CINAHL, PsychINFO, Abstracts in Social Gerontology, AgeLine, AMED, and Scopus databases from database inception to February 18, 2018, using the Medical Subject Headings aged 65 and older, accidental falls, and dancing. Study selection: This systematic review and meta-analysis included 29 randomized clinical trials that evaluated a dance-based mind-motor activity in healthy older adults with regard to fall risk, fall rate, or well
, ), and in Denmark the rate increased from 23% in 2004 to 34% in 2012 (Fridberg & Henriksen, ). A recent study in Denmark showed that while the rates of volunteering remained stable for younger seniors, there was a large increase over time among those aged 67–77 years (Amilon & Larsen, ). Researchers have partly explained the increasing in the rates of older volunteers by increasing heath and active ageing lifestyles among older adults (e.g., Amilon & Larsen, ; Schippers & Conen, ). Partly the development has (...) been explained by volunteer work becoming increasingly professionalized and the recruitment strategies to integrate olderpeople in the volunteer organisations being increasingly efficient (Amilon & Larsen, ). Many countries in Europe have explicit strategies to increase older adults' volunteering (Ehlers, Naegele, & Reichert, ). In the United States, specific programmes aiming to integrate the aging population into voluntary work exist. Some programmes are organised in local nonprofit
Indacaterol acetate/mometasone furoate (Atectura Breezhaler) for the maintenance treatment for asthma in adults and adolescents of 12 years and older Indacaterol acetate/mometasone furoate (Atectura® Breezhaler®) for the maintenance treatment for asthma in adults and adolescents of 12 years and older | Report | National Health Care Institute You are here: Indacaterol acetate/mometasone furoate (Atectura® Breezhaler®) for the maintenance treatment for asthma in adults and adolescents of 12 years (...) and older Search within English part of National Health Care Institute Search Indacaterol acetate/mometasone furoate (Atectura® Breezhaler®) for the maintenance treatment for asthma in adults and adolescents of 12 years and older Zorginstituut Nederland has completed its assessment whether indacaterol acetate/mometasone furoate (Atectura® Breezhaler®) can be included in the Medication Reimbursement System (GVS). The Zorginstituut's advice is to include Atectura® Breezhaler® in List 1B of the GVS
Abdominal aorta aneurysm (AAA) screening of men aged 65 Abdominal aorta aneurysm (AAA) screening of men aged 65 - NIPH Search for: Søk Menu To top level Close Infectious diseases & Vaccines Mental & Physical health Environment & Lifestyle Health in Norway Quality & Knowledge Research & Access to data About NIPH Close Abdominal aorta aneurysm (AAA) screening of men aged 65 Order Download: Key message Abdominal aortic aneurysm (AAA) is a weakening of the aortic wall resulting in an abnormal (...) dilatation of the abdominal aortic artery. AAAs bears the risk of rupture, which is a dramatic emergency condition with a high risk of death. In Norway, about 1% of all deaths among men older than 65 years are caused by AAA rupture. The mortality rate due to AAA rupture is approximately 75%, with about half of the deaths occurring before the patient reaches the hospital. The larger the AAA, the higher is the risk of rupture. Prevalence of AAA among men varies across countries from approx. 1.5-3
Effect of exercise training for five years on all cause mortality in older adults-the Generation 100 study: randomised controlled trial. To evaluate the effect of five years of supervised exercise training compared with recommendations for physical activity on mortality in older adults (70-77 years).Randomised controlled trial.General population of older adults in Trondheim, Norway.1567 of 6966 individuals born between 1936 and 1942.Participants were randomised to two sessions weekly of high (...) intensity interval training at about 90% of peak heart rate (HIIT, n=400), moderate intensity continuous training at about 70% of peak heart rate (MICT, n=387), or to follow the national guidelines for physical activity (n=780; control group); all for five years.All cause mortality. An exploratory hypothesis was that HIIT lowers mortality more than MICT.Mean age of the 1567 participants (790 women) was 72.8 (SD 2.1) years. Overall, 87.5% of participants reported to have overall good health, with 80
of about 3.5 for covid-19. The model predicted that school closures and isolation of younger people would increase the total number of deaths, albeit postponed to a second and subsequent waves. The findings of this study suggest that prompt interventions were shown to be highly effective at reducing peak demand for intensive care unit (ICU) beds but also prolong the epidemic, in some cases resulting in more deaths long term. This happens because covid-19 related mortality is highly skewed towards older (...) Effect of school closures on mortality from coronavirus disease 2019: old and new predictions. To replicate and analyse the information available to UK policymakers when the lockdown decision was taken in March 2020 in the United Kingdom.Independent calculations using the CovidSim code, which implements Imperial College London's individual based model, with data available in March 2020 applied to the coronavirus disease 2019 (covid-19) epidemic.Simulations considering the spread of covid-19
that they are overlooked in the consultation with health care professionals because of their age. They have felt that they are being belittled and not taken seriously. It may therefore be justified to investigate, problematise and, if necessary, improve the attitudes of health care personnel towards pain in the older persons. In studies with qualitative methodology, both personnel in health care and older persons 1 with pain have experienced that health care professionals have insufficient knowledge about pain (...) For a description of the age composition of the patient populations in included studies and the handling of assessing the certainty of the scientific basis, see “Main findings”. Background and aim Several common pain drugs may not be suitable for the treatment of older persons (65 years and older) due to an increased risk of adverse events, which in some cases may be serious. In the light of this problem, long-term pain conditions are the focus of this evaluation. In addition, several problems and shortcomings
: 10.1001/jamanetworkopen.2020.12252. Effects of Candesartan vs Lisinopril on Neurocognitive Function in Older Adults With Executive Mild Cognitive Impairment: A Randomized Clinical Trial , , , , , , , , Affiliations Expand Affiliations 1 Department of Neurology, Emory University School of Medicine, Atlanta, Georgia. 2 Division of General Medicine and Geriatrics, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia. 3 Division of Cardiology, Department of Medicine, Emory (...) are associated with a unique cognitive protection. It is unclear if this is due to reduced blood pressure (BP) or angiotensin receptors type 1 blockade. Objective: To determine neurocognitive effects of candesartan vs lisinopril in older adults with mild cognitive impairment (MCI). Design, setting, and participants: This randomized clinical trial included participants aged 55 years or older with MCI and hypertension. Individuals were withdrawn from prior antihypertensive therapy and randomized in a 1 to 1
mortality and discharge disposition in elderly trauma patients over the age of 65 y. J Surg Res 2018;230:13-9. Alabaf Sabbaghi S, De Souza D, Sarikonda P, Keevil VL, Wallis SJ, Romero-Ortuno R. Allocating patients to geriatric medicine wards in a tertiary university hospital in England: A service evaluation of the Specialist Advice for the Frail Elderly (SAFE) team. Aging Medicine 2018;1:120-124. Basic D, Shanley C. Frailty in an older inpatient population: using the clinical frailty scale to predict (...) patient outcomes. J Aging Health 2015;27:670-85. Cardona M, Lewis ET, Kristensen MR, Skjot-Arkil H, Ekmann AA, Nygaard HH, et al. Predictive validity of the CriSTAL tool for short-term mortality in olderpeople presenting at Emergency Departments: a prospective study. Eur Geriatr Med 2018;9:891-901. Cheung A, Haas B, Ringer TJ, McFarlan A, Wong CL. Canadian Study of Health and Aging Clinical Frailty Scale: Does It Predict Adverse Outcomes among Geriatric Trauma Patients? J Am Coll Surg 2017;225:658
Bendamustine for relapsed multiple myeloma (all ages) NHS England » Bendamustine for relapsed multiple myeloma (all ages) Cookies on the NHS England and NHS Improvement website We’ve put some small files called cookies on your device to make our site work. We’d also like to use analytics cookies. These send information about how our site is used to a service called Google Analytics. We use this information to improve our site. Let us know if this is OK. We’ll use a cookie to save your choice (...) . You can before you choose. Change my preferences I'm OK with analytics cookies Search Search Menu . If you are a member of the public looking for health advice, go to the . And if you are looking for the latest travel information, and advice about the government response to the outbreak, go to the . Bendamustine for relapsed multiple myeloma (all ages) Document first published: 9 July 2020 Page updated: 22 July 2020 Topic: , , Publication type: , Document PDF 112 KB 15 pages Document PDF 58 KB 5
and work with each RACF on their prevention plans. This is an urgent need and we recommend the following immediate interventions: 1. RACFs must be linked to their Local Health Network (or equivalent). 2. Local Health Networks must have an outbreak management team and plan that is linked with RACFs. The team should include people with expertise in geriatric medicine, health care of olderpeople in aged care, infectious diseases and public health. Senior executives of LHNs need to lead these teams (...) Statement on COVID-19 Response in Residential Aged Care Facilities Statement on COVID-19 Response in Residential Aged Care Facilities Background Older Australians and New Zealanders living in residential aged care facilities (RACF) are more at risk of becoming very unwell or dying from COVID-19. The protection and care of olderpeople living in RACF is one of the most significant challenges faced by Australia and New Zealand during the pandemic. ANZSGM supports the use of the most up-to-date
-CoV-2 spike protein (S-2P) in healthy adults. The trial was expanded to include 40 older adults, who were stratified according to age (56 to 70 years or ≥71 years). All the participants were assigned sequentially to receive two doses of either 25 μg or 100 μg of vaccine administered 28 days apart.Solicited adverse events were predominantly mild or moderate in severity and most frequently included fatigue, chills, headache, myalgia, and pain at the injection site. Such adverse events were dose (...) -dependent and were more common after the second immunization. Binding-antibody responses increased rapidly after the first immunization. By day 57, among the participants who received the 25-μg dose, the anti-S-2P geometric mean titer (GMT) was 323,945 among those between the ages of 56 and 70 years and 1,128,391 among those who were 71 years of age or older; among the participants who received the 100-μg dose, the GMT in the two age subgroups was 1,183,066 and 3,638,522, respectively. After the second
In older patients with NSTE-ACS, clopidogrel safely reduced bleeding compared with ticagrelor at 1 year. Gimbel M, Qaderdan K, Willemsen L, et al. Clopidogrel versus ticagrelor or prasugrel in patients aged 70 years or older with non-ST-elevation acute coronary syndrome (POPular AGE): the randomised, open-label, non-inferiority trial. Lancet. 2020;395:1374-81. 32334703.
Age- and Weight-Adapted Dose of Prasugrel Versus Standard Dose of Ticagrelor in Patients With Acute Coronary Syndromes : Results From a Randomized Trial. The efficacy and safety of a reduced dose of prasugrel versus a standard dose of ticagrelor in elderly patients or those with a low body weight presenting with an acute coronary syndrome (ACS) are unknown.To investigate the effect of an age- and weight-adapted dose of prasugrel versus a standard dose of ticagrelor in patients with ACS (...) . (ClinicalTrials.gov: NCT01944800).Prespecified analysis of the multicenter, randomized ISAR-REACT 5 trial.23 centers in Germany and Italy.3997 patients with ACS planned for invasive management.Participants were randomly assigned to receive a standard dose of ticagrelor or prasugrel (reduced dose in the elderly or low-weight group and standard dose in the neither elderly nor low-weight group).The efficacy end point was a composite of death, myocardial infarction, or stroke, and the safety end point was bleeding
Environmental and behavioural interventions for reducing physical activity limitation and preventing falls in olderpeople with visual impairment. Impairment of vision is associated with a decrease in activities of daily living. Avoidance of physical activity in older adults with visual impairment can lead to functional decline and is an important risk factor for falls. The rate of falls and fractures is higher in olderpeople with visual impairment than in age-matched visually normal older (...) February 2020, with no language restrictions.Eligible studies were randomized controlled trials (RCTs) and quasi-randomized controlled trials (Q-RCTs) that compared environmental interventions, behavioral interventions or both, versus control (usual care or no intervention); or that compared different types of environmental or behavioral interventions. Eligible study populations were olderpeople (aged 60 and over) with irreversible visual impairment, living in their own homes or in residential