Latest & greatest articles for geriatrics

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Top results for geriatrics

181. Validation of the Elderly Risk Assessment Index in the Emergency Department (Abstract)

Validation of the Elderly Risk Assessment Index in the Emergency Department The Elderly Risk Assessment (ERA) score is a validated index for primary care patients that predict hospitalizations, mortality, and Emergency Department (ED) visits. The score incorporates age, prior hospital days, marital status, and comorbidities. Our aim was to validate the ERA score in ED patients.Observational cohort study of patients age ≥ 60 presenting to an academic ED over a 1-year period. Regression analyses (...) were performed for associations with outcomes (hospitalization, return visits and death). Medians, interquartile range (IQR), odds ratios (OR) and 95% confidence intervals (CI) were calculated.The cohort included 27,397 visits among 18,607 patients. Median age 74 years (66-82), 48% were female and 59% were married. Patients from 54% of visits were admitted to the hospital, 16% returned to the ED within 30 days, and 18% died within one year. Higher ERA scores were associated with: hospital admission

2020 EvidenceUpdates

182. Treatment of Older Patients With Mantle Cell Lymphoma (MCL): Long-Term Follow-Up of the Randomized European MCL Elderly Trial

Treatment of Older Patients With Mantle Cell Lymphoma (MCL): Long-Term Follow-Up of the Randomized European MCL Elderly Trial Treatment of Older Patients With Mantle Cell Lymphoma (MCL): Long-Term Follow-Up of the Randomized European MCL Elderly Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced features (...) a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation J Clin Oncol Actions , 38 (3), 248-256 2020 Jan 20 Treatment of Older Patients With Mantle Cell Lymphoma (MCL): Long-Term Follow-Up of the Randomized European MCL Elderly Trial , , , , , , , , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 University Medical Center Groningen

2020 EvidenceUpdates

183. Developing an all-age response to meet the age-specific needs of service users

Developing an all-age response to meet the age-specific needs of service users NHS England » Developing an all-age response to meet the age-specific needs of service users Search Search Menu Developing an all-age response to meet the age-specific needs of service users Document first published: 22 January 2020 Page updated: 22 January 2020 Topic: Publication type: Document PDF 476 KB 14 pages

2020 NHS England

184. Failure of Traditional Risk Factors to Adequately Predict Cardiovascular Events in Older Populations

patients. Among those aged 85 years and older, some traditional risk factors were not associated with ASCVD events. Better risk models are needed to appropriately inform treatment decision making for the growing population of older adults. Keywords: model validation; older adults; risk heterogeneity; risk prediction. © 2020 The American Geriatrics Society. Similar articles MG Nanna et al. J Gen Intern Med. 2019. PMID 31667745. The performance of the PCE for ASCVD risk estimation in older adults (...) to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation J Am Geriatr Soc Actions 2020 Jan 20 [Online ahead of print] Failure of Traditional Risk Factors to Adequately Predict Cardiovascular Events in Older Populations , , , , , Affiliations Expand Affiliations 1 Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio. 2 Department of Quantitative Health

2020 EvidenceUpdates

185. Comparison of the Effect of Age (< 75 Versus >/= 75) on the Efficacy and Safety of Dual Therapy (Dabigatran+Clopidogrel or Ticagrelor) Versus Triple Therapy (Warfarin+Aspirin+Clopidogrel or Ticagrelor) in Patients With Atrial Fibrillation After Percutaneo Full Text available with Trip Pro

to treatment, 1,026 (37.7%) were categorized into older and 1,699 (62.3%) into younger age groups. Dabigatran 110 mg dual therapy lowered bleeding risk versus warfarin triple therapy in older (hazard ratio [HR] 0.67; 95% confidence interval [CI] 0.51 to 0.89) and younger patients (HR 0.40; 95% CI 0.30 to 0.54); interaction p value: 0.0125. Dabigatran 150 mg dual therapy lowered bleeding risk versus warfarin triple therapy in younger patients (HR 0.57; 95% CI 0.44 to 0.74), whereas no benefit could (...) Comparison of the Effect of Age (< 75 Versus >/= 75) on the Efficacy and Safety of Dual Therapy (Dabigatran+Clopidogrel or Ticagrelor) Versus Triple Therapy (Warfarin+Aspirin+Clopidogrel or Ticagrelor) in Patients With Atrial Fibrillation After Percutaneo Comparison of the Effect of Age ( - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History

2020 EvidenceUpdates

186. Incident psychiatric comorbidity following stress disorder diagnoses in Danish school-aged children: prospective population-based study

Incident psychiatric comorbidity following stress disorder diagnoses in Danish school-aged children: prospective population-based study Incident Psychiatric Comorbidity Following Stress Disorder Diagnoses in Danish School-Aged Children: Prospective Population-Based Study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other (...) characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Br J Psychiatry Actions , 1-6 2019 Nov 22 [Online ahead of print] Incident Psychiatric Comorbidity Following Stress Disorder Diagnoses in Danish School-Aged Children: Prospective Population-Based Study , , , , , , Affiliations Expand Affiliations 1 Research Associate

2020 EvidenceUpdates

187. Valproate and Retinoic Acid in Combination With Decitabine in Elderly Nonfit Patients With Acute Myeloid Leukemia: Results of a Multicenter, Randomized, 2 x 2, Phase II Trial (Abstract)

inhibitor valproate and all-trans retinoic acid (ATRA) in treatment-naive elderly patients with acute myeloid leukemia (AML).Two hundred patients (median age, 76 years; range, 61-92 years) ineligible for induction chemotherapy received decitabine (20 mg/m2 intravenously, days 1 to 5) alone (n = 47) or in combination with valproate (n = 57), ATRA (n = 46), or valproate + ATRA (n = 50). The primary endpoint was objective response, defined as complete and partial remission, tested at a one-sided (...) Valproate and Retinoic Acid in Combination With Decitabine in Elderly Nonfit Patients With Acute Myeloid Leukemia: Results of a Multicenter, Randomized, 2 x 2, Phase II Trial DNA-hypomethylating agents are studied in combination with other epigenetic drugs, such as histone deacetylase inhibitors or differentiation inducers (eg, retinoids), in myeloid neoplasias. A randomized, phase II trial with a 2 × 2 factorial design was conducted to investigate the effects of the histone deacetylase

2020 EvidenceUpdates

188. Older adults: cost-effective commissioning

and implementing services to support older people's healthy ageing. Published 28 January 2020 From: Documents Ref: PHE publications gateway reference GW-1008 If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email . Please tell us what format you need. It will help us if you say what assistive technology you use. Ref: PHE publications gateway reference GW-1008 If you use assistive technology (such as a screen reader) and need (...) on identified interventions to support older people, generated through a literature review. The return on investment (ROI) tool: can be adapted to local conditions presents results showing the economic benefits of each intervention has a built-in user guide Local authorities and clinical commissioning groups can use these resources to improve the provision of services for older people. Published 28 January 2020 Related content Explore the topic Is this page useful? Thank you for your feedback Help us

2020 Public Health England

189. Hygiene and emollient interventions for maintaining skin integrity in older people in hospital and residential care settings. (Abstract)

Hygiene and emollient interventions for maintaining skin integrity in older people in hospital and residential care settings. Ageing has a degenerative effect on the skin, leaving it more vulnerable to damage. Hygiene and emollient interventions may help maintain skin integrity in older people in hospital and residential care settings; however, at present, most care is based on "tried and tested" practice, rather than on evidence.To assess the effects of hygiene and emollient interventions (...) for maintaining skin integrity in older people in hospital and residential care settings.We searched the Cochrane Skin Specialised Register, CENTRAL, MEDLINE, Embase, and CINAHL, up to January 2019. We also searched five trials registers.Randomised controlled trials comparing hygiene and emollient interventions versus placebo, no intervention, or standard practices for older people aged ≥ 60 years in hospital or residential care settings.We used standard methodological procedures as expected by Cochrane

2020 Cochrane

190. Testosterone Treatment in Adult Men With Age-Related Low Testosterone: A Clinical Guideline From the American College of Physicians. (Abstract)

Testosterone Treatment in Adult Men With Age-Related Low Testosterone: A Clinical Guideline From the American College of Physicians. The American College of Physicians (ACP) developed this guideline to provide clinical recommendations based on the current evidence of the benefits and harms of testosterone treatment in adult men with age-related low testosterone. This guideline is endorsed by the American Academy of Family Physicians.The ACP Clinical Guidelines Committee based (...) these recommendations on a systematic review on the efficacy and safety of testosterone treatment in adult men with age-related low testosterone. Clinical outcomes were evaluated by using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) system and included sexual function, physical function, quality of life, energy and vitality, depression, cognition, serious adverse events, major adverse cardiovascular events, and other adverse events.The target audience includes all clinicians

2020 Annals of Internal Medicine

191. Effectiveness and Cost-Effectiveness of Human Papillomavirus Vaccination Through Age 45 Years in the United States. (Abstract)

effects from the current HPV vaccination program.The current HPV vaccination program is predicted to be cost saving. Extending vaccination to older ages is predicted to produce small additional health benefits and result in substantially higher incremental cost-effectiveness ratios than the current recommendation.Centers for Disease Control and Prevention. (...) Effectiveness and Cost-Effectiveness of Human Papillomavirus Vaccination Through Age 45 Years in the United States. In the United States, the routine age for human papillomavirus (HPV) vaccination is 11 to 12 years, with catch-up vaccination through age 26 years for women and 21 years for men. U.S. vaccination policy on use of the 9-valent HPV vaccine in adult women and men is being reviewed.To evaluate the added population-level effectiveness and cost-effectiveness of extending the current U.S

2020 Annals of Internal Medicine

192. Predicting 6-Month Mortality for Older Adults Hospitalized With Acute Myocardial Infarction: A Cohort Study. (Abstract)

study. (ClinicalTrials.gov: NCT01755052).94 hospitals throughout the United States.3006 persons aged 75 years or older who were hospitalized with AMI and discharged alive.Functional impairments were assessed during hospitalization via direct measurement (cognition, mobility, muscle strength) or self-report (vision, hearing). Clinical variables associated with mortality in prior risk models were ascertained by chart review. Seventy-two candidate variables were selected for inclusion, and backward (...) Predicting 6-Month Mortality for Older Adults Hospitalized With Acute Myocardial Infarction: A Cohort Study. Older adults with acute myocardial infarction (AMI) have higher prevalence of functional impairments, including deficits in cognition, strength, and sensory domains, than their younger counterparts.To develop and evaluate the prognostic utility of a risk model for 6-month post-AMI mortality in older adults that incorporates information about functional impairments.Prospective cohort

2020 Annals of Internal Medicine

193. Best-practice prevention alone or with conventional or biological caries management for 3- to 7-year-olds: the FiCTION three-arm RCT Full Text available with Trip Pro

Best-practice prevention alone or with conventional or biological caries management for 3- to 7-year-olds: the FiCTION three-arm RCT Best-practice prevention alone or with conventional or biological caries management for 3- to 7-year-olds: the FiCTION three-arm RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try

2020 NIHR HTA programme

194. Measuring and optimising the efficiency of community hospital inpatient care for older people: the MoCHA mixed-methods study Full Text available with Trip Pro

Measuring and optimising the efficiency of community hospital inpatient care for older people: the MoCHA mixed-methods study Measuring and optimising the efficiency of community hospital inpatient care for older people: the MoCHA mixed-methods study Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search (...) Tucker 5 , Pam Enderby 6 , John Gladman 7 , Elizabeth Teale 1 , Jean-Christophe Thiebaud 3 1 Academic Unit of Elderly Care and Rehabilitation, University of Leeds, Leeds, UK 2 Academic Unit of Health Economics, University of Leeds, Leeds, UK 3 Institute for Transport Studies, University of Leeds, Leeds, UK 4 NHS Benchmarking Network, Manchester, UK 5 Community Hospitals Association, Crowborough, UK 6 School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK 7 University

2020 NIHR HTA programme

195. A revised teaching assistant-led extracurricular physical activity programme for 8- to 10-year-olds: the Action 3:30R feasibility cluster RCT Full Text available with Trip Pro

A revised teaching assistant-led extracurricular physical activity programme for 8- to 10-year-olds: the Action 3:30R feasibility cluster RCT A revised teaching assistant-led extracurricular physical activity programme for 8- to 10-year-olds: the Action 3:30R feasibility cluster RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from

2020 NIHR HTA programme

196. Multicomponent hospital-led interventions to reduce hospital stay for older adults following elective surgery: a systematic review Full Text available with Trip Pro

, Rob Anderson 1 1 Exeter Health Services and Delivery Research Evidence Synthesis Centre, Institute of Health Research, University of Exeter Medical School, University of Exeter, Exeter, UK 2 Department of Healthcare for Older People, Royal Devon & Exeter NHS Foundation Trust, Exeter, UK 3 Royal Devon & Exeter NHS Foundation Trust, Exeter, UK 4 School of Health Professions, Faculty of Health & Human Sciences, University of Plymouth, Plymouth, UK * Corresponding author Email: {{metadata.Journal (...) Multicomponent hospital-led interventions to reduce hospital stay for older adults following elective surgery: a systematic review Multicomponent hospital-led interventions to reduce hospital stay for older adults following elective surgery: a systematic review Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website

2020 NIHR HTA programme

197. Mortality Implications of Prediabetes and Diabetes in Older Adults

delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Diabetes Care Actions , 43 (2), 382-388 Feb 2020 Mortality Implications of Prediabetes and Diabetes in Older Adults , , , , , , , Affiliations Expand Affiliations 1 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. 2 Division of Cardiology and National Institute for Prevention and Cardiovascular Health, National University of Ireland, Galway, Ireland. 3 Department of Geriatric (...) @jhu.edu. PMID: 31776141 PMCID: (available on 2021-02-01 ) DOI: Item in Clipboard Full-text links Cite Abstract Objective: Diabetes in older age is heterogeneous, and the treatment approach varies by patient characteristics. We characterized the short-term all-cause and cardiovascular mortality risk associated with hyperglycemia in older age. Research design and methods: We included 5,791 older adults in the Atherosclerosis Risk in Communities Study who attended visit 5 (2011-2013; ages 66-90 years

2020 EvidenceUpdates

198. State of Ageing 2019 infographics

and Chelsea Disability free life expectancy Total life expectancySource: +"CFMMBOE/"NJO4NJUIFUBM 5IF%ZOBNJDTPG"HF JOH &WJEFODFGSPNUIF&OHMJTI-POHJUVEJOBM4UVEZPG"HFJOH 8BWF 1 in 5 people aged 55-64 have a health problem that limits the kind of work they can doSource: +"CFMMBOE/"NJO4NJUIFUBM 5IF%ZOBNJDTPG"HF JOH &WJEFODFGSPNUIF&OHMJTI-POHJUVEJOBM4UVEZPG"HFJOH 8BWF More than a quarter of the poorest men aged 50 and over are smokers, compared to 5% of the wealthiest 27% 5% 5% 19% 1 oor FTURu J O UJMe 8 FB (...) &WJEFODFGSPNUIF&OHMJTI-POHJUVEJOBM4UVEZPG"HFJOH 8BWF Compared to the wealthiest quintile, the poorest quintile of men aged 50 and over are: 3x 2x 2x NPr FMJ L e M Z U o h B W e chronic heart disease N or FMJ L e M Z U o h B W e Type 2 diabetes N or FMJ L e M Z U o h BWe arthritis4PVSDF0tDFPG/BUJPOBM4UBUJTUJDT .FBTVSJOHOBUJPOBMXFMMCFJOH EPNBJOTBOENFBTVSFT CBTFE - POFMJOFTTB T FDUT QFPQMFP GBMMBHFT 8% 6% 5% 3% 3% 25 to 34 year olds 50 to 64 year olds 35 to 49 year olds 65 to 74 year olds 75 and over

2020 The Centre for Ageing Better

199. Measuring ageing: An introduction to the Ageing Better Measures Framework

Better 2019 Local monitoring and evaluation We are also making use of the ABMF at a local level. We are working with the Greater Manchester Combined Authority, Leeds City Council and Leeds Older People’s Forum, supporting them, as well as other members of the UK Network of Age-Friendly Communities, in their use of data and measures to understand local experiences of ageing and monitor progress. We look forward to continuing to work with these and other partners interested in measuring what matters (...) Measuring ageing: An introduction to the Ageing Better Measures Framework Measuring ageing: An introduction to the Ageing Better Measures Framework Centre for Ageing Better January 20193 © Centre for Ageing Better 2019 About the Centre for Ageing Better The Centre for Ageing Better is a charity, funded by an endowment from The National Lottery Community Fund, working to create a society where everyone enjoys a good later life. We want more people to be in fulfilling work, in good health, living

2020 The Centre for Ageing Better

200. Ageing and mobility: A grand challenge

as a barrier to use and improvement. This results in difficulties for individuals to navigate the systems and weakens system-wide incentives for integration and innovation. On average at least one-third of older people report unmet travel needs. It worsens with age, and women were reported to be more affected than men. (Luiu et al 2016). Mobility challenges faced in later life6 © Centre for Ageing Better 20197 © Centre for Ageing Better 2019 As we grow older, we are more likely to have health conditions (...) % of older people cannot reach a hospital within 30 minutes by public transport. (Future of Mobility: Evidence Review). Accessible and inclusive new technologies, services and business models Opportunities for innovation8 © Centre for Ageing Better 2019 Specific issues to address in their development include: - New vehicles, including Autonomous Vehicles, need to be designed to be accessible for people with limited mobility. - Addressing the door to vehicle portion of the journey, which can

2020 The Centre for Ageing Better