Latest & greatest articles for furosemide

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Top results for furosemide

21. International randomised controlled trial of acetazolamide and furosemide in posthaemorrhagic ventricular dilatation in infancy. International PHVD Drug Trial Group. (PubMed)

International randomised controlled trial of acetazolamide and furosemide in posthaemorrhagic ventricular dilatation in infancy. International PHVD Drug Trial Group. Furosemide and acetazolamide are widely used in the treatment of posthaemorrhagic ventricular dilatation (PHVD) in the hope of avoiding the need for surgical management, but this approach has not been evaluated in a controlled trial. This multicentre randomised controlled trial tested the hypothesis that these drugs would reduce (...) the rate of shunt placement and increase disability-free survival at 1 year of age.Between 1992 and 1996, 177 infants aged less than 3 months past term, and with ventricular width more than 4 mm above 97th centile after intraventricular haemorrhage, were randomly assigned standard therapy alone or standard therapy plus treatment with acetazolamide (100 mg/kg daily) and furosemide (1 mg/kg daily). A minimisation algorithm ensured balance between groups with respect to both referral centre

1998 Lancet

22. Randomised trial of high-dose isosorbide dinitrate plus low-dose furosemide versus high-dose furosemide plus low-dose isosorbide dinitrate in severe pulmonary oedema. (PubMed)

Randomised trial of high-dose isosorbide dinitrate plus low-dose furosemide versus high-dose furosemide plus low-dose isosorbide dinitrate in severe pulmonary oedema. Nitrates and furosemide, commonly administered in the treatment of pulmonary oedema, have not been compared in a prospective clinical trial. We compared the efficacy and safety of these drugs in a randomised trial of patients with severe pulmonary oedema and oxygen saturation below 90%.Patients presenting to mobile emergency units (...) with signs of congestive heart failure were treated with oxygen 10 L/min, intravenous furosemide 40 mg, and morphine 3 mg bolus. 110 patients were randomly assigned either to group A, who received isosorbide dinitrate (3 mg bolus administered intravenously every 5 min; n=56) or to group B, who received furosemide (80 mg bolus administered intravenously every 15 min, as well as isosorbide dinitrate 1 mg/h, increased every 10 min by 1 mg/h; n=54). Six patients were withdrawn on the basis of chest

1998 Lancet

23. Comparison of therapies with torasemide or furosemide in patients with congestive heart failure from a pharmacoeconomic viewpoint

Comparison of therapies with torasemide or furosemide in patients with congestive heart failure from a pharmacoeconomic viewpoint Comparison of therapies with torasemide or furosemide in patients with congestive heart failure from a pharmacoeconomic viewpoint Comparison of therapies with torasemide or furosemide in patients with congestive heart failure from a pharmacoeconomic viewpoint Spannheimer A, Goertz A, Dreckmann-Behrendt B Record Status This is a critical abstract of an economic (...) evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of loop diuretics for the treatment of patients suffering from congestive heart failure (CHF). Two loop diuretics were compared, furosemide and torasemide. Type of intervention Treatment. Economic study type Cost-effectiveness analysis

1998 NHS Economic Evaluation Database.

24. Effects of saline, mannitol, and furosemide to prevent acute decreases in renal function induced by radiocontrast agents. (PubMed)

Effects of saline, mannitol, and furosemide to prevent acute decreases in renal function induced by radiocontrast agents. Injections of radiocontrast agents are a frequent cause of acute decreases in renal function, occurring most often in patients with chronic renal insufficiency and diabetes mellitus.We prospectively studied 78 patients with chronic renal insufficiency (mean [+/- SD] serum creatinine concentration, 2.1 +/- 0.6 mg per deciliter [186 +/- 53 mumol per liter]) who underwent (...) cardiac angiography. The patients were randomly assigned to receive 0.45 percent saline alone for 12 hours before and 12 hours after angiography, saline plus mannitol, or saline plus furosemide. The mannitol and furosemide were given just before angiography. Serum creatinine was measured before and for 48 hours after angiography, and urine was collected for 24 hours after angiography. An acute radiocontrast-induced decrease in renal function was defined as an increase in the base-line serum creatinine

1994 NEJM

25. Comparison of continuous versus intermittent furosemide administration in postoperative pediatric cardiac patients

Comparison of continuous versus intermittent furosemide administration in postoperative pediatric cardiac patients PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

1992 PedsCCM Evidence-Based Journal Club

26. Protective effect of inhaled furosemide on allergen-induced early and late asthmatic reactions. (PubMed)

Protective effect of inhaled furosemide on allergen-induced early and late asthmatic reactions. The movement of ions and water across the membranes of bronchial cells is part of the control of the bronchial obstructive response to physical stimuli. In a double-blind, randomized, crossover study, we compared the effect of an aerosol of the loop diuretic furosemide with that of a placebo on the early (within 60 minutes) and late (4 to 12 hours) asthmatic responses to a specific inhaled allergen (...) of 35 +/- 5 percent and an increase of 301 +/- 40 percent between 4 and 12 hours (late response). After furosemide administration (4 ml; 10 mg per milliliter), the early response to inhaled allergen was markedly attenuated in all the subjects, and the late response in all but one. The maximal changes in the FEV1 and specific airway resistance were, respectively, a decrease of 11 +/- 2 percent and an increase of 61 +/- 2 percent between 0 and 60 minutes and a decrease of 20 +/- 4 percent

1989 NEJM

27. Furosemide and theophylline. (PubMed)

Furosemide and theophylline. 4062102 1985 12 05 2013 11 21 0003-4819 103 6 ( Pt 1) 1985 Dec Annals of internal medicine Ann. Intern. Med. Furosemide and theophylline. 957 Carpentiere G G Marino S S Castello F F eng Clinical Trial Letter Randomized Controlled Trial United States Ann Intern Med 0372351 0003-4819 7LXU5N7ZO5 Furosemide C137DTR5RG Theophylline AIM IM Adult Drug Interactions Furosemide pharmacology Humans Middle Aged Theophylline blood 1985 12 1 1985 12 1 0 1 1985 12 1 0 0 ppublish

1985 Annals of Internal Medicine

28. Furosemide promotes patent ductus arteriosus in premature infants with the respiratory-distress syndrome. (PubMed)

Furosemide promotes patent ductus arteriosus in premature infants with the respiratory-distress syndrome. Furosemide stimulates the renal synthesis of prostaglandin E2, a potent dilator of the ductus arteriosus. We administered this drug to 33 premature infants with the respiratory-distress syndrome, to determine whether it increased the incidence of patent ductus arteriosus. Chlorothiazide, a diuretic that does not stimulate prostaglandin E synthesis, was used as the control drug in 33 other (...) infants. During the study, the incidence of patent ductus arteriosus was significantly higher (P less than 0.02) in the furosemide group (18 of 33 infants) than in the chlorothiazide group (8 of 33). Eleven infants in the furosemide group and seven in the chlorothiazide group required ductal ligation (P greater than 0.2). An additional six infants (all from the furosemide group) who did not have evidence of a patent ductus during the study were later found to have one. Overall survival was 76 and 61

1983 NEJM

29. Furosemide compared with hydrochlorothiazide. Long-term treatment of hypertension. (PubMed)

Furosemide compared with hydrochlorothiazide. Long-term treatment of hypertension. In a double-blind crossover study, the effectiveness of furosemide, 40 mg twice daily, was compared with hydrochlorothiazide, 50 mg twice daily, in hypertensive patients. Both hydrochlorothiazide and furosemide significantly reduced blood pressure (BP) during three months of therapy. However, the fall in BP was consistently greater with hydrochlorothiazide than with furosemide, although the difference

1978 JAMA