Latest & greatest articles for fatigue

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on fatigue or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on fatigue and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for fatigue

101. Cancer-related fatigue and rehabilitation: a randomized controlled multicenter trial comparing physical training combined with cognitive-behavioral therapy with physical training only and with no intervention

Cancer-related fatigue and rehabilitation: a randomized controlled multicenter trial comparing physical training combined with cognitive-behavioral therapy with physical training only and with no intervention 20651011 2010 10 04 2010 10 29 2015 11 19 1538-6724 90 10 2010 Oct Physical therapy Phys Ther Cancer-related fatigue and rehabilitation: a randomized controlled multicenter trial comparing physical training combined with cognitive-behavioral therapy with physical training only (...) and with no intervention. 1413-25 10.2522/ptj.20090212 Research suggests that cancer rehabilitation reduces fatigue in survivors of cancer. To date, it is unclear what type of rehabilitation is most beneficial. This randomized controlled trial compared the effect on cancer-related fatigue of physical training combined with cognitive behavioral therapy with physical training alone and with no intervention. In this multicenter randomized controlled trial, 147 survivors of cancer were randomly assigned to a group

EvidenceUpdates2010

102. Effect of retirement on major chronic conditions and fatigue: French GAZEL occupational cohort study.

Effect of retirement on major chronic conditions and fatigue: French GAZEL occupational cohort study. OBJECTIVES: To determine, using longitudinal analyses, if retirement is followed by a change in the risk of incident chronic diseases, depressive symptoms, and fatigue. Design Prospective study with repeat measures from 7 years before to 7 years after retirement. SETTING: Large French occupational cohort (the GAZEL study), 1989-2007. Participants 11 246 men and 2858 women. MAIN OUTCOME MEASURES (...) : Respiratory disease, diabetes, coronary heart disease and stroke, mental fatigue, and physical fatigue, measured annually by self report over the 15 year observation period; depressive symptoms measured at four time points. RESULTS: The average number of repeat measurements per participant was 12.1. Repeated measures logistic regression with generalised estimating equations showed that the cumulative prevalence of self reported respiratory disease, diabetes, and coronary heart disease and stroke increased

BMJ2010 Full Text: Link to full Text with Trip Pro

103. MS quality of life, depression, and fatigue improve after mindfulness training: a randomized trial

MS quality of life, depression, and fatigue improve after mindfulness training: a randomized trial 20876468 2010 09 29 2010 10 18 2016 10 19 1526-632X 75 13 2010 Sep 28 Neurology Neurology MS quality of life, depression, and fatigue improve after mindfulness training: a randomized trial. 1141-9 10.1212/WNL.0b013e3181f4d80d Health-related quality of life (HRQOL) is often much reduced among individuals with multiple sclerosis (MS), and incidences of depression, fatigue, and anxiety are high. We (...) examined effects of a mindfulness-based intervention (MBI) compared to usual care (UC) upon HRQOL, depression, and fatigue among adults with relapsing-remitting or secondary progressive MS. A total of 150 patients were randomly assigned to the intervention (n = 76) or to UC (n = 74). MBI consisted of a structured 8-week program of mindfulness training. Assessments were made at baseline, postintervention, and 6 months follow-up. Primary outcomes included disease-specific and disease-aspecific HRQOL

EvidenceUpdates2010 Full Text: Link to full Text with Trip Pro

104. Effectiveness of an online fatigue self-management programme for people with chronic neurological conditions: a randomized controlled trial

Effectiveness of an online fatigue self-management programme for people with chronic neurological conditions: a randomized controlled trial 20543022 2010 08 12 2011 03 16 2010 08 12 1477-0873 24 8 2010 Aug Clinical rehabilitation Clin Rehabil Effectiveness of an online fatigue self-management programme for people with chronic neurological conditions: a randomized controlled trial. 727-44 10.1177/0269215509360648 To evaluate an online fatigue self-management programme in a sample of adults (...) with chronic neurological conditions. Randomized controlled trial. Online fatigue self-management programme delivered across Australia. Ninety-five people with fatigue secondary to multiple sclerosis, Parkinson's disease or post-polio syndrome. An online fatigue self-management programme, an information-only fatigue self-management programme and a control group. Groups were compared at pre test, post test and at three months on primary outcomes using the Fatigue Impact Scale, Activity Card Sort

EvidenceUpdates2010

105. A randomized controlled trial of home-based exercise for cancer-related fatigue in women during and after chemotherapy with or without radiation therapy.

A randomized controlled trial of home-based exercise for cancer-related fatigue in women during and after chemotherapy with or without radiation therapy. 20467301 2010 06 23 2010 10 08 2017 02 20 1538-9804 33 4 2010 Jul-Aug Cancer nursing Cancer Nurs A randomized controlled trial of home-based exercise for cancer-related fatigue in women during and after chemotherapy with or without radiation therapy. 245-57 10.1097/NCC.0b013e3181ddc58c Few studies have evaluated an individualized home-based (...) exercise prescription during and after cancer treatment. The purpose of this study was to evaluate the effectiveness of a home-based exercise training intervention, the Pro-self Fatigue Control Program on the management of cancer-related fatigue. Participants (N = 119) were randomized into 1 of 3 groups: group 1 received the exercise prescription throughout the study; group 2 received their exercise prescription after completing cancer treatment; and group 3 received usual care. Patients completed

EvidenceUpdates2010 Full Text: Link to full Text with Trip Pro

106. Dehydroepiandrosterone (DHEA) substitution treatment for severe fatigue in DHEA-deficient patients with primary Sjogren`s Syndrome

Dehydroepiandrosterone (DHEA) substitution treatment for severe fatigue in DHEA-deficient patients with primary Sjogren`s Syndrome 20191499 2010 03 01 2010 04 05 2013 11 21 2151-4658 62 1 2010 Jan 15 Arthritis care & research Arthritis Care Res (Hoboken) Dehydroepiandrosterone (DHEA) substitution treatment for severe fatigue in DHEA-deficient patients with primary Sjögren's syndrome. 118-24 10.1002/acr.20022 Primary Sjögren's syndrome (SS) is characterized by fatigue and low levels of serum (...) dehydroepiandrosterone/dehydroepiandrosterone sulfate (DHEA/DHEAS). Our aim was to study whether SS patients with severe fatigue and low serum DHEAS values benefit from DHEA substitution (50 mg/day). A multicenter, investigator-based, powered, randomized controlled clinical trial (crossover, washout design) using fatigue as the primary outcome measure was performed on patients with primary SS (n = 107) who had a general fatigue score > or =14 on the 20-item Multiple Fatigue Inventory (MFI-20), combined with age

EvidenceUpdates2010

107. Prevalence of xenotropic murine leukaemia virus-related virus in patients with chronic fatigue syndrome in the Netherlands: retrospective analysis of samples from an established cohort.

Prevalence of xenotropic murine leukaemia virus-related virus in patients with chronic fatigue syndrome in the Netherlands: retrospective analysis of samples from an established cohort. OBJECTIVE: The presence of the retrovirus xenotropic murine leukaemia virus-related virus (XMRV) has been reported in peripheral blood mononuclear cells of patients with chronic fatigue syndrome. Considering the potentially great medical and social relevance of such a discovery, we investigated whether (...) this finding could be confirmed in an independent European cohort of patients with chronic fatigue syndrome. DESIGN: Analysis of a well defined cohort of patients and matched neighbourhood controls by polymerase chain reaction. SETTING: Certified (ISO 15189) laboratory of clinical virology in a university hospital in the Netherlands. Population Between December 1991 and April 1992, peripheral blood mononuclear cells were isolated from 76 patients and 69 matched neighbourhood controls. In this study we

BMJ2010 Full Text: Link to full Text with Trip Pro

108. Carnitine for fatigue in multiple sclerosis.

Carnitine for fatigue in multiple sclerosis. BACKGROUND: Fatigue is reported to occur in up to 92% of patients with multiple sclerosis (MS) and has been described as the most debilitating of all MS symptoms by 28% to 40% of MS patients. OBJECTIVES: To assess whether carnitine (enteral or intravenous) supplementation can improve the quality of life and reduce the symptoms of fatigue in patients with MS-related fatigue and to identify any adverse effects of carnitine when used for this purpose (...) , United States) of carnitine formulation was contacted to determine if they knew of other clinical trials. No language restrictions were applied. SELECTION CRITERIA: Full reports of published and unpublished randomized controlled trials and quasi-randomized trials of any carnitine intervention in adults with a clinical diagnosis of fatigue associated with multiple sclerosis were included. DATA COLLECTION AND ANALYSIS: Data from the eligible trials was extracted and coded using a standardized data

Cochrane2010

109. Randomised controlled trial: Nurse-delivered, home-based pragmatic rehabilitation has a short-term effect on improving fatigue in people with chronic fatigue syndrome compared with usual GP care, but effects were not sustained at 1 year

Randomised controlled trial: Nurse-delivered, home-based pragmatic rehabilitation has a short-term effect on improving fatigue in people with chronic fatigue syndrome compared with usual GP care, but effects were not sustained at 1 year Nurse-delivered, home-based pragmatic rehabilitation has a short-term effect on improving fatigue in people with chronic fatigue syndrome compared with usual GP care, but effects were not sustained at 1 year | Evidence-Based Nursing This site uses cookies (...) , home-based pragmatic rehabilitation has a short-term effect on improving fatigue in people with chronic fatigue syndrome compared with usual GP care, but effects were not sustained at 1 year Article Text Therapeutics Randomised controlled trial Nurse-delivered, home-based pragmatic rehabilitation has a short-term effect on improving fatigue in people with chronic fatigue syndrome compared with usual GP care, but effects were not sustained at 1 year Jo Armes Statistics from Altmetric.com

Evidence-Based Nursing (Requires free registration)2010

110. Cross-sectional: Small survey finds that new mothers use self-care approaches to manage fatigue more often than other strategies such as seeking help from others

Cross-sectional: Small survey finds that new mothers use self-care approaches to manage fatigue more often than other strategies such as seeking help from others Small survey finds that new mothers use self-care approaches to manage fatigue more often than other strategies such as seeking help from others | Evidence-Based Nursing This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in via your Society Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in via your Society Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Small survey finds that new mothers use self-care approaches to manage fatigue more often than other strategies such as seeking help from others Article

Evidence-Based Nursing (Requires free registration)2010

111. [Chronic fatigue syndrome: state of the evidence and assessment of intervention modalities in Quebec]

[Chronic fatigue syndrome: state of the evidence and assessment of intervention modalities in Quebec] Le syndrome de fatigue chronique. Etat des connaissances et evaluation des modes d'intervention au Quebec [Chronic fatigue syndrome: state of the evidence and assessment of intervention modalities in Quebec] Le syndrome de fatigue chronique. Etat des connaissances et evaluation des modes d'intervention au Quebec [Chronic fatigue syndrome: state of the evidence and assessment of intervention (...) modalities in Quebec] Rouleau G, Ceppi U, Hjelholt Pedersen V, Dagenais P Record Status This is a bibliographic record of an ongoing health technology assessment being undertaken by a member of INAHTA. Links to the published report and any other relevant documentation will be added when available. Citation Rouleau G, Ceppi U, Hjelholt Pedersen V, Dagenais P. Le syndrome de fatigue chronique. Etat des connaissances et evaluation des modes d'intervention au Quebec. [Chronic fatigue syndrome: state

Health Technology Assessment (HTA) Database.2010

112. Effect of epoetin alfa on survival and cancer treatment-related anemia and fatigue in patients receiving radical radiotherapy with curative intent for head and neck cancer

Effect of epoetin alfa on survival and cancer treatment-related anemia and fatigue in patients receiving radical radiotherapy with curative intent for head and neck cancer 19884550 2009 11 26 2009 12 23 2015 11 19 1527-7755 27 34 2009 Dec 01 Journal of clinical oncology : official journal of the American Society of Clinical Oncology J. Clin. Oncol. Effect of epoetin alfa on survival and cancer treatment-related anemia and fatigue in patients receiving radical radiotherapy with curative intent (...) for head and neck cancer. 5751-6 10.1200/JCO.2009.22.3693 To evaluate the effect of epoetin alfa on local disease-free survival (DFS), overall survival (OS), and cancer treatment-related anemia and fatigue in patients with head and neck cancer receiving radical radiotherapy with curative intent. Patients (N = 301) with hemoglobin (Hb) less than 15 g/dL were randomly assigned in a ratio of 1:1 to receive radiotherapy plus epoetin alfa (10,000 U subcutaneously [SC] three times weekly if baseline Hb

EvidenceUpdates2010

113. Nurse led, home based self help treatment for patients in primary care with chronic fatigue syndrome: randomised controlled trial.

Nurse led, home based self help treatment for patients in primary care with chronic fatigue syndrome: randomised controlled trial. 20418251 2010 04 26 2010 05 11 2017 02 20 1756-1833 340 2010 Apr 23 BMJ (Clinical research ed.) BMJ Nurse led, home based self help treatment for patients in primary care with chronic fatigue syndrome: randomised controlled trial. c1777 10.1136/bmj.c1777 bmj.c1777 To evaluate the effectiveness of home delivered pragmatic rehabilitation-a programme of gradually (...) increasing activity designed collaboratively by the patient and the therapist-and supportive listening-an approach based on non-directive counselling-for patients in primary care with chronic fatigue syndrome/myalgic encephalomyelitis or encephalitis (CFS/ME). Single blind, randomised, controlled trial. 186 general practices across the north west of England between February 2005 and May 2007. 296 patients aged 18 or over with CFS/ME (median illness duration seven years) diagnosed using the Oxford

BMJ2010 Full Text: Link to full Text with Trip Pro

114. Traditional Chinese medicinal herbs for the treatment of idiopathic chronic fatigue and chronic fatigue syndrome.

Traditional Chinese medicinal herbs for the treatment of idiopathic chronic fatigue and chronic fatigue syndrome. BACKGROUND: Chronic fatigue is increasingly common. Conventional medical care is limited in treating chronic fatigue, leading some patients to use traditional Chinese medicine therapies, including herbal medicine. OBJECTIVES: To assess the effectiveness of traditional Chinese medicine herbal products in treating idiopathic chronic fatigue and chronic fatigue syndrome. SEARCH (...) STRATEGY: The following databases were searched for terms related to traditional Chinese medicine, chronic fatigue, and clinical trials: CCDAN Controlled Trials Register (July 2009), MEDLINE (1966-2008), EMBASE (1980-2008), AMED (1985-2008), CINAHL (1982-2008), PSYCHINFO (1985-2008), CENTRAL (Issue 2 2008), the Chalmers Research Group PedCAM Database (2004), VIP Information (1989-2008), CNKI (1976-2008), OCLC Proceedings First (1992-2008), Conference Papers Index (1982-2008), and Dissertation Abstracts

Cochrane2009

115. Association of resident fatigue and distress with perceived medical errors.

Association of resident fatigue and distress with perceived medical errors. CONTEXT: Fatigue and distress have been separately shown to be associated with medical errors. The contribution of each factor when assessed simultaneously is unknown. OBJECTIVE: To determine the association of fatigue and distress with self-perceived major medical errors among resident physicians using validated metrics. DESIGN, SETTING, AND PARTICIPANTS: Prospective longitudinal cohort study of categorical (...) and preliminary internal medicine residents at Mayo Clinic, Rochester, Minnesota. Data were provided by 380 of 430 eligible residents (88.3%). Participants began training from 2003 to 2008 and completed surveys quarterly through February 2009. Surveys included self-assessment of medical errors, linear analog self-assessment of overall quality of life (QOL) and fatigue, the Maslach Burnout Inventory, the PRIME-MD depression screening instrument, and the Epworth Sleepiness Scale. MAIN OUTCOME MEASURES

JAMA2009

116. Interventions for post-stroke fatigue.

Interventions for post-stroke fatigue. BACKGROUND: Fatigue after stroke is common and distressing to patients. The best way to treat this fatigue is uncertain. Theoretically, several different interventions may be of benefit. OBJECTIVES: To determine whether any treatment for fatigue after stroke reduces the proportion of patients with fatigue, or fatigue severity, or both, and to determine the effect of treatment on health-related quality of life, disability, dependency and death, and whether (...) randomised controlled trials of any intervention in patients with stroke where fatigue was a primary or secondary endpoint. DATA COLLECTION AND ANALYSIS: The two review authors who scrutinised references independently extracted data. We performed a narrative review; we had intended to perform a meta-analysis but this was not possible as the interventions were too diverse for data to be combined. MAIN RESULTS: We identified three trials. One randomised 83 patients with emotional disturbance after stroke

Cochrane2009

117. Fatigue during breast cancer radiotherapy: An initial randomized study of cognitive-behavioral therapy plus hypnosis

Fatigue during breast cancer radiotherapy: An initial randomized study of cognitive-behavioral therapy plus hypnosis 19450037 2009 05 19 2009 07 13 2009 05 19 0278-6133 28 3 2009 May Health psychology : official journal of the Division of Health Psychology, American Psychological Association Health Psychol Fatigue during breast cancer radiotherapy: an initial randomized study of cognitive-behavioral therapy plus hypnosis. 317-22 10.1037/a0013582 The study purpose was to test the effectiveness (...) of a psychological intervention combining cognitive-behavioral therapy and hypnosis (CBTH) to treat radiotherapy-related fatigue. Women (n = 42) scheduled for breast cancer radiotherapy were randomly assigned to receive standard medical care (SMC) (n = 20) or a CBTH intervention (n = 22) in addition to SMC. Participants assigned to receive CBTH met individually with a clinical psychologist. CBTH participants received training in hypnosis and CBT. Participants assigned to the SMC control condition did not meet

EvidenceUpdates2009

118. Effects of pulmonary rehabilitation on fatigue, functional status and health perceptions in patients with chronic obstructive pulmonary disease: a randomized controlled trial

Effects of pulmonary rehabilitation on fatigue, functional status and health perceptions in patients with chronic obstructive pulmonary disease: a randomized controlled trial 19164400 2009 01 23 2009 04 08 2009 01 23 0269-2155 23 2 2009 Feb Clinical rehabilitation Clin Rehabil Effects of pulmonary rehabilitation on fatigue, functional status and health perceptions in patients with chronic obstructive pulmonary disease: a randomized controlled trial. 125-36 10.1177/0269215508096174 To test (...) the effects of pulmonary rehabilitation on fatigue, functional status and health perceptions in patients with chronic obstructive pulmonary disease. Randomized controlled trial. Pulmonary outpatient department. Thirty patients randomly assigned to a rehabilitation (3 men, 9 women, mean age 66 (+/-2) years) or a control group (10 men, 4 women, mean age 64 (+/-2) years). The patients in the rehabilitation group participated in a multidisciplinary rehabilitation programme comprising exercise training twice

EvidenceUpdates2009

119. Short-term effects of aerobic exercise on functional capacity, fatigue, and quality of life in patients with post-polio syndrome

Short-term effects of aerobic exercise on functional capacity, fatigue, and quality of life in patients with post-polio syndrome 19164403 2009 01 23 2009 04 08 2009 01 23 0269-2155 23 2 2009 Feb Clinical rehabilitation Clin Rehabil Short-term effects of aerobic exercise on functional capacity, fatigue, and quality of life in patients with post-polio syndrome. 155-63 10.1177/0269215508098893 To investigate and compare the impact of hospital and home exercise programmes on aerobic capacity (...) , fatigue, and quality of life in patients with post-polio syndrome. A prospective, randomized controlled trial. Department of Physical Medicine and Rehabilitation, University Hospital. Thirty-two patients were divided into two groups for either hospital- or home-based aerobic exercise programme. Patients were assessed before and after the rehabilitation programme, with respect to functional capacity (pVo2), fatigue (Fatigue Severity Scale, Fatigue Impact Scale) and quality of life (Nottingham Heath

EvidenceUpdates2009

120. Psychosocial interventions for reducing fatigue during cancer treatment in adults.

Psychosocial interventions for reducing fatigue during cancer treatment in adults. BACKGROUND: Fatigue is a common symptom in cancer patients receiving active treatment. There are a limited number of reviews evaluating interventions for fatigue during active treatment, and they are restricted to patients with advanced cancer, or to patients during radiotherapy. To date there is no systematic review on psychosocial interventions for fatigue during cancer treatment. OBJECTIVES: To evaluate (...) if psychosocial interventions are effective in reducing fatigue in cancer patients receiving active treatment for cancer, and which types of psychosocial interventions are the most effective. SEARCH STRATEGY: In September 2008 we searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library), PUBMED, MEDLINE, EMBASE, CINAHL and PsycINFO, and checked the reference lists. SELECTION CRITERIA: Randomised controlled trials (RCTs) were included which evaluated psychosocial

Cochrane2009