Latest & greatest articles for fatigue

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on fatigue or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on fatigue and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for fatigue

82. Acupuncture for Cancer-Related Fatigue in Patients With Breast Cancer: A Pragmatic Randomized Controlled Trial

Acupuncture for Cancer-Related Fatigue in Patients With Breast Cancer: A Pragmatic Randomized Controlled Trial 23109700 2012 12 18 2013 05 07 2013 07 16 1527-7755 30 36 2012 Dec 20 Journal of clinical oncology : official journal of the American Society of Clinical Oncology J. Clin. Oncol. Acupuncture for cancer-related fatigue in patients with breast cancer: a pragmatic randomized controlled trial. 4470-6 10.1200/JCO.2012.41.6222 We aimed to assess the effectiveness of acupuncture for cancer (...) -related fatigue (CRF) in patients with breast cancer. We conducted a pragmatic, randomized controlled trial comparing acupuncture with enhanced usual care. Three hundred two outpatients with breast cancer participated. We randomly assigned 75 patients to usual care and 227 patients to acupuncture plus usual care (random assignment of 1:3 respectively) with minimization controlling for baseline general fatigue and maintenance treatment. Treatment was delivered by acupuncturists once a week for 6 weeks

EvidenceUpdates2012

83. Modafinil for sleep disorders and fatigue secondary to multiple sclerosis: a review of the clinical efficacy and safety

Modafinil for sleep disorders and fatigue secondary to multiple sclerosis: a review of the clinical efficacy and safety Modafinil for sleep disorders and fatigue secondary to multiple sclerosis: a review of the clinical efficacy and safety Modafinil for sleep disorders and fatigue secondary to multiple sclerosis: a review of the clinical efficacy and safety CADTH Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation (...) of the quality of this assessment has been made for the HTA database. Citation CADTH. Modafinil for sleep disorders and fatigue secondary to multiple sclerosis: a review of the clinical efficacy and safety . Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). 2012 Authors' conclusions No conclusions can be drawn on the efficacy of modafinil compared to methylphenidate or amphetamines due to the absence of head-to-head clinical trials. Relative to placebo, modafinil was associated

Health Technology Assessment (HTA) Database.2012

85. Cognitive and graded activity training can alleviate persistent fatigue after stroke: a randomized, controlled trial

Cognitive and graded activity training can alleviate persistent fatigue after stroke: a randomized, controlled trial 22308241 2012 03 28 2012 05 22 2016 11 25 1524-4628 43 4 2012 Apr Stroke Stroke Cognitive and graded activity training can alleviate persistent fatigue after stroke: a randomized, controlled trial. 1046-51 10.1161/STROKEAHA.111.632117 Fatigue is a common, persistent consequence of stroke, and no evidence-based treatments are currently available to alleviate fatigue. A new (...) treatment combining cognitive therapy (CO) with graded activity training (GRAT), called COGRAT, was developed to alleviate fatigue and fatigue-related symptoms. This study compared the effectiveness of the COGRAT intervention with a CO-only intervention after a 3-month qualification period without intervention. This randomized, controlled, assessor-blind clinical trial was conducted in 8 rehabilitation centers. Eighty-three stroke patients (>4 months after stroke) were randomly assigned to 12 weeks

EvidenceUpdates2012

86. Carnitine for fatigue in multiple sclerosis.

Carnitine for fatigue in multiple sclerosis. BACKGROUND: Fatigue is reported to occur in up to 92% of patients with multiple sclerosis (MS) and has been described as the most debilitating of all MS symptoms by 28% to 40% of MS patients. OBJECTIVES: To assess whether carnitine (enteral or intravenous) supplementation can improve the quality of life and reduce the symptoms of fatigue in patients with MS-related fatigue and to identify any adverse effects of carnitine when used for this purpose (...) conducted. Personal contact with MS experts and a manufacturer (Source Naturals, United States) of carnitine formulation was contacted to determine if they knew of other clinical trials. No language restrictions were applied. SELECTION CRITERIA: Full reports of published and unpublished randomized controlled trials and quasi-randomized trials of any carnitine intervention in adults affected by multiple sclerosis with a clinical diagnosis of fatigue associated with multiple sclerosis were included. DATA

Cochrane2012

87. A Progressive Postresection Walking Program Significantly Improves Fatigue and Health-Related Quality of Life in Pancreas and Periampullary Cancer Patients

A Progressive Postresection Walking Program Significantly Improves Fatigue and Health-Related Quality of Life in Pancreas and Periampullary Cancer Patients 22321518 2012 04 02 2012 07 27 2015 11 19 1879-1190 214 4 2012 Apr Journal of the American College of Surgeons J. Am. Coll. Surg. A progressive postresection walking program significantly improves fatigue and health-related quality of life in pancreas and periampullary cancer patients. 463-75; discussion 475-7 10.1016/j.jamcollsurg (...) .2011.12.017 As patients with pancreas and periampullary cancer (PPC) experience improved survival rates and longevity, the focus shifts toward living life while surviving cancer. Fatigue is the most commonly reported symptom in all cancer patients. Exercise has been found to effectively decrease fatigue levels and improve physical functioning in cancer patients. One hundred two patients with resected PPC consented to participate in this study and were randomized to either an intervention group (IG

EvidenceUpdates2012

88. Efficacy of exercise interventions in modulating cancer-related fatigue among adult cancer survivors: a meta-analysis

Efficacy of exercise interventions in modulating cancer-related fatigue among adult cancer survivors: a meta-analysis Efficacy of exercise interventions in modulating cancer-related fatigue among adult cancer survivors: a meta-analysis Efficacy of exercise interventions in modulating cancer-related fatigue among adult cancer survivors: a meta-analysis Brown JC, Huedo-Medina TB, Pescatello LS, Pescatello SM, Ferrer RA, Johnson BT CRD summary The authors concluded that exercise reduced cancer (...) -related fatigue especially in programmes that involved moderate-intensity resistance exercise among older cancer survivors and in programmes that were guided by theory. The authors' conclusions reflect the evidence presented and are likely to be reliable. Authors' objectives To evaluate the efficacy of exercise as a nonpharmacologic intervention to reduce cancer-related fatigue among adult cancer patients. Searching CINAHL, MEDLINE, EMBASE and Scopus were searched to February 2010. Search terms were

DARE.2012

90. Cost-effectiveness of counselling, graded-exercise and usual care for chronic fatigue: evidence from a randomised trial in primary care

Cost-effectiveness of counselling, graded-exercise and usual care for chronic fatigue: evidence from a randomised trial in primary care Cost-effectiveness of counselling, graded-exercise and usual care for chronic fatigue: evidence from a randomised trial in primary care Cost-effectiveness of counselling, graded-exercise and usual care for chronic fatigue: evidence from a randomised trial in primary care Sabes-Figuera R, McCrone P, Hurley M, King M, Donaldson AN, Ridsdale L Record Status (...) This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study evaluated the cost-effectiveness of three treatments for chronic fatigue, lasting more than three months. The authors concluded that no clear economic advantage was found for any therapy; counselling

NHS Economic Evaluation Database.2012

91. Systematic review of the impact of erythropoiesis-stimulating agents on fatigue in dialysis patients

Systematic review of the impact of erythropoiesis-stimulating agents on fatigue in dialysis patients Systematic review of the impact of erythropoiesis-stimulating agents on fatigue in dialysis patients Systematic review of the impact of erythropoiesis-stimulating agents on fatigue in dialysis patients Johansen KL, Finkelstein FO, Revicki DA, Evans C, Wan S, Gitlin M, Agodoa IL CRD summary The authors concluded that partial correction of anaemia, with erythropoiesis-stimulating agents, improved (...) fatigue in patients with end-stage renal disease, who were on dialysis. The evidence indicated improved fatigue outcomes, but the authors' conclusions may not be sufficiently cautious, due to a lack of well-designed studies. Authors' objectives To evaluate erythropoiesis-stimulating agents, in the treatment of anaemia, to improve fatigue, in patients with end-stage renal disease, who were on dialysis. Searching MEDLINE and EMBASE were searched, for articles published in English, to June 2010. Search

DARE.2012

92. Body composition, physical fitness, functional performance, quality of life, and fatigue benefits of exercise for prostate cancer patients: a systematic review

Body composition, physical fitness, functional performance, quality of life, and fatigue benefits of exercise for prostate cancer patients: a systematic review Body composition, physical fitness, functional performance, quality of life, and fatigue benefits of exercise for prostate cancer patients: a systematic review Body composition, physical fitness, functional performance, quality of life, and fatigue benefits of exercise for prostate cancer patients: a systematic review Keogh JW, MacLeod (...) of life or fatigue among people with prostate cancer who underwent an exercise intervention for at least four weeks. Studies that included patients with other cancers were required to report outcomes separately for prostate cancer. All studies in the review restricted entry to participants who had prostate cancer without co-existing problems that could contra-indicate an exercise programme. Mean participant age ranged from 66 to 72 years. Mean time since diagnosis ranged from two to four years. Most participants

DARE.2012

93. Internet-based CBT improves fatigue severity, physical function and school attendance in adolescents with chronic fatigue syndrome

Internet-based CBT improves fatigue severity, physical function and school attendance in adolescents with chronic fatigue syndrome Internet-based CBT improves fatigue severity, physical function and school attendance in adolescents with chronic fatigue syndrome | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username (...) * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Internet-based CBT improves fatigue severity, physical function and school attendance in adolescents with chronic fatigue syndrome Article Text Therapeutics Internet-based CBT improves fatigue severity, physical function and school attendance

Evidence-Based Mental Health2012

94. Effectiveness of internet-based cognitive behavioural treatment for adolescents with chronic fatigue syndrome (FITNET): a randomised controlled trial.

Effectiveness of internet-based cognitive behavioural treatment for adolescents with chronic fatigue syndrome (FITNET): a randomised controlled trial. 22385683 2012 04 16 2012 05 02 2015 06 16 1474-547X 379 9824 2012 Apr 14 Lancet (London, England) Lancet Effectiveness of internet-based cognitive behavioural treatment for adolescents with chronic fatigue syndrome (FITNET): a randomised controlled trial. 1412-8 10.1016/S0140-6736(12)60025-7 Chronic fatigue syndrome is characterised by persistent (...) fatigue and severe disability. Cognitive behavioural therapy seems to be a promising treatment, but its availability is restricted. We developed Fatigue In Teenagers on the interNET (FITNET), the first dedicated internet-based therapeutic program for adolescents with this disorder, and compared its effectiveness with that of usual care. Adolescents aged 12-18 years with chronic fatigue syndrome were assigned to FITNET or usual care in a 1:1 ratio at one tertiary treatment centre in the Netherlands

Lancet2012

96. [Treatment of chronic fatigue syndrome CFS/ME]

[Treatment of chronic fatigue syndrome CFS/ME] Behandling av kronisk utmattelsessyndrom CFS/ME [Treatment of chronic fatigue syndrome CFS/ME] Behandling av kronisk utmattelsessyndrom CFS/ME [Treatment of chronic fatigue syndrome CFS/ME] Larun L, Brurberg KG, Fonhus MS, Kirkerhei I Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Larun L (...) , Brurberg KG, Fonhus MS, Kirkerhei I. Behandling av kronisk utmattelsessyndrom CFS/ME. [Treatment of chronic fatigue syndrome CFS/ME] Oslo: Norwegian Knowledge Centre for the Health Services (NOKC). Rapid Reviews. 2011 Authors' conclusions Cognitive behavioural therapy and graded exercise therapy is likely to be effective for people with chronic fatigue syndrome. For other treatment strategies the quality of evidence is very low or even non-existing implying that more research is needed before we can

Health Technology Assessment (HTA) Database.2011

97. Insufficient evidence for interventions for post-stroke fatigue

Insufficient evidence for interventions for post-stroke fatigue PEARLS Practical Evidence About Real Life Situations PEARLS are succinct summaries of Cochrane Systematic Reviews for primary care practitioners. They Insufficient evidence for interventions for post-stroke fatigue Clinical question How effective are interventions for post-stroke fatigue? Bottom line This review found 3 small, randomised controlled trials that recruited people with a stroke to 3 treatments - 2 different drug (...) treatments (fluoxetine and tirilazad) and one chronic disease self-management programme. At follow-up, there was no difference in fatigue levels between the patients who received the active treatments and those who received usual care or placebo. However, the trials were too small to provide firm conclusions and further trials are required. Currently, there is insufficient evidence to guide practice in treating fatigue following stroke. Caveat There were only 3 completed studies, providing data

Cochrane PEARLS2011

98. Exercise is an effective treatment modality for reducing cancer-related fatigue and improving physical capacity in cancer patients and survivors: a meta-analysis

Exercise is an effective treatment modality for reducing cancer-related fatigue and improving physical capacity in cancer patients and survivors: a meta-analysis Exercise is an effective treatment modality for reducing cancer-related fatigue and improving physical capacity in cancer patients and survivors: a meta-analysis Exercise is an effective treatment modality for reducing cancer-related fatigue and improving physical capacity in cancer patients and survivors: a meta-analysis McMillan EM (...) , Newhouse IJ CRD summary The authors concluded that exercise interventions were beneficial for reducing cancer-related fatigue for patients and survivors of diverse cancer sites and treatment stages. The authors' conclusions reflect the evidence presented but the reliability of the conclusions is uncertain given the lack of quality assessment and small number of studies for some analyses. Authors' objectives To evaluate the effects of exercise intervention strategies for the management of cancer-related

DARE.2011

100. Comparison of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and specialist medical care for chronic fatigue syndrome (PACE): a randomised trial.

Comparison of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and specialist medical care for chronic fatigue syndrome (PACE): a randomised trial. 21334061 2011 03 07 2011 03 23 2016 10 19 1474-547X 377 9768 2011 Mar 05 Lancet (London, England) Lancet Comparison of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and specialist medical care for chronic fatigue syndrome (PACE): a randomised trial. 823-36 10.1016/S0140-6736(11)60096-2 (...) Trial findings show cognitive behaviour therapy (CBT) and graded exercise therapy (GET) can be effective treatments for chronic fatigue syndrome, but patients' organisations have reported that these treatments can be harmful and favour pacing and specialist health care. We aimed to assess effectiveness and safety of all four treatments. In our parallel-group randomised trial, patients meeting Oxford criteria for chronic fatigue syndrome were recruited from six secondary-care clinics in the UK

Lancet2011 Full Text: Link to full Text with Trip Pro