Latest & greatest articles for fatigue

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Top results for fatigue

181. Childhood predictors of self reported chronic fatigue syndrome/myalgic encephalomyelitis in adults: national birth cohort study.

Childhood predictors of self reported chronic fatigue syndrome/myalgic encephalomyelitis in adults: national birth cohort study. OBJECTIVE: To study childhood risk factors for chronic fatigue syndrome in adult life. DESIGN: Examination of data from the 1970 British birth cohort. PARTICIPANTS: 16,567 babies born 5-11 April 1970, followed up at 5, 10, 16, and 29-30 years. MAIN OUTCOME MEASURES: Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) identified by self report at age 30 years (...) . Data from childhood from questionnaires given to parents and teachers. Maternal mental health assessed with the malaise inventory. RESULTS: 93 (0.8%, 95% confidence interval 0.7 to 1.0) of 11 261 participants reported ever having CFS/ME, and 48 (0.4%, 0.3 to 0.6) had the condition currently. Higher risk of CFS/ME was associated with having a limiting longstanding condition in childhood (odds ratio 2.3, 1.4 to 3.9), female sex (2.3, 1.4 to 2.6), and high social class in childhood (2.2, 1.4 to 3.5

BMJ2004 Full Text: Link to full Text with Trip Pro

182. General practitioners' perceptions of chronic fatigue syndrome and beliefs about its management, compared with irritable bowel syndrome: qualitative study.

General practitioners' perceptions of chronic fatigue syndrome and beliefs about its management, compared with irritable bowel syndrome: qualitative study. OBJECTIVES: To compare general practitioners' perceptions of chronic fatigue syndrome and irritable bowel syndrome and to consider the implications of their perceptions for treatment. DESIGN: Qualitative analysis of transcripts of group discussions. PARTICIPANTS AND SETTING: A randomly selected sample of 46 general practitioners in England (...) . RESULTS: The participants tended to stereotype patients with chronic fatigue syndrome as having certain undesirable traits. This stereotyping was due to the lack of a precise bodily location; the reclassification of the syndrome over time; transgression of social roles, with patients seen as failing to conform to the work ethic and "sick role" and conflict between doctor and patient over causes and management. These factors led to difficulties for many general practitioners in managing patients

BMJ2004 Full Text: Link to full Text with Trip Pro

183. Fatigue in neurological disorders.

Fatigue in neurological disorders. Chronic fatigue is a typical symptom of neurological diseases, and is most disabling in multiple sclerosis, postpoliomyelitis, poststroke, and in chronic fatigue syndrome. Disorders of neuromuscular junction transmission and metabolic diseases cause muscle fatigability, which is characterised by failure to sustain the force of muscle contraction (peripheral fatigue). Fatigue is also seen in diseases that affect the central, peripheral, and autonomic nervous (...) systems (central fatigue). Enhanced perception of effort and limited endurance of sustained physical and mental activities are the main characteristics of central fatigue. Metabolic and structural lesions that disrupt the usual process of activation in pathways interconnecting the basal ganglia, thalamus, limbic system, and higher cortical centre are implicated in the pathophysiological process of central fatigue. A state of pre-existing relative hypocortisolaemia might sensitise the hypothalamic

Lancet2004

184. Chronic fatigue syndrome, treatment

Chronic fatigue syndrome, treatment Chronic fatigue syndrome, treatment Chronic fatigue syndrome, treatment Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Chronic fatigue syndrome, treatment. Lansdale: HAYES, Inc.. Directory Publication. 2004 Authors' objectives A number of different treatments, including pharmacologic, behavioral, and physical (...) therapy modalities, have been used for chronic fatigue syndrome (CFS). The goal of treatment is relief of symptoms, which include chronic fatigue and weakness, along with a variety of other symptoms, such as fever, myalgia, arthralgia, headache, confusion or impaired cognitive function, and sometimes depression. Final publication URL The report may be purchased from: Indexing Status Subject indexing assigned by CRD MeSH Fatigue Syndrome, Chronic /therapys Language Published English Country of organisation United

Health Technology Assessment (HTA) Database.2004

185. Chronic fatigue syndrome, diagnosis

Chronic fatigue syndrome, diagnosis Chronic fatigue syndrome, diagnosis Chronic fatigue syndrome, diagnosis Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Chronic fatigue syndrome, diagnosis. Lansdale: HAYES, Inc.. Directory Publication. 2004 Authors' objectives Chronic fatigue syndrome (CFS) is characterized by a state of profound, persistent, and debilitating (...) fatigue that significantly impairs daily activity level. It is associated with a variety of complaints, chiefly related to the neuromuscular, neuropsychiatric, and immunological systems. The goal of the diagnostic process for this disorder is to exclude more clearly definable disorders though traditional medical assessment as well as special studies and tests. This process employs specific diagnostic criteria, particularly those associated with the psychiatric, immunologic, infectious

Health Technology Assessment (HTA) Database.2004

186. Cost-effectiveness of cognitive behavioural therapy, graded exercise and usual care for patients with chronic fatigue in primary care

Cost-effectiveness of cognitive behavioural therapy, graded exercise and usual care for patients with chronic fatigue in primary care Cost-effectiveness of cognitive behavioural therapy, graded exercise and usual care for patients with chronic fatigue in primary care Cost-effectiveness of cognitive behavioural therapy, graded exercise and usual care for patients with chronic fatigue in primary care McCrone P, Ridsdale L, Darbishire L, Seed P Record Status This is a critical abstract (...) of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Three strategies for the treatment of patients with chronic fatigue syndrome (CFS) were examined. The strategies were cognitive-behavioural therapy (CBT), graded exercise therapy (GET), and usual general practitioner (GP) care plus

NHS Economic Evaluation Database.2004

187. RCPCH evidence based guideline for the management of CFS/ME (chronic fatigue syndrome/myalgic encephalopathy) in children and young people

RCPCH evidence based guideline for the management of CFS/ME (chronic fatigue syndrome/myalgic encephalopathy) in children and young people

Royal College of Paediatrics and Child Health2004

189. Effect of galantamine hydrobromide in chronic fatigue syndrome: a randomized controlled trial.

Effect of galantamine hydrobromide in chronic fatigue syndrome: a randomized controlled trial. 15353532 2004 09 08 2004 09 13 2016 10 17 1538-3598 292 10 2004 Sep 08 JAMA JAMA Effect of galantamine hydrobromide in chronic fatigue syndrome: a randomized controlled trial. 1195-204 There is no established pharmacological treatment for the core symptoms of chronic fatigue syndrome (CFS). Galantamine hydrobromide, an acetyl cholesterone inhibitor, has pharmacological properties that might benefit (...) patients with CFS. To compare the efficacy and tolerability of galantamine hydrobromide in patients with CFS. Randomized, double-blind trial conducted June 1997 through July 1999 at 35 outpatient centers in the United Kingdom (n = 17), United States (n = 14), the Netherlands (n = 2), Sweden (n = 1), and Belgium (n = 1) involving 434 patients with a clinical diagnosis of CFS (modified US Centers for Disease Control and Prevention criteria). A total of 89 patients were randomly assigned to receive 2.5 mg

JAMA2004

190. Exercise therapy for chronic fatigue syndrome.

Exercise therapy for chronic fatigue syndrome. BACKGROUND: Chronic fatigue syndrome (CFS) is an illness characterised by persistent medically unexplained fatigue. CFS is a serious health-care problem with a prevalence of up to 3%. Treatment strategies for CFS include psychological, physical and pharmacological interventions. OBJECTIVES: To investigate the relative effectiveness of exercise therapy and control treatments for CFS. SEARCH STRATEGY: CCDANCTR-Studies and CENTRAL were searched using (...) "Chronic Fatigue" and Exercise. The Journal of Chronic Fatigue Syndrome and CFS conferences were handsearched. Experts in the field were contacted. Clinicaltrials.gov and controlled-trials.com were searched. SELECTION CRITERIA: Only Randomised Controlled Trials (RCT) including participants with a clinical diagnosis of CFS and of any age were included. DATA COLLECTION AND ANALYSIS: The full articles of studies identified were inspected by two reviewers (ME and HMG). Continuous measures of outcome were

Cochrane2004

191. Assessment and management of cancer-related fatigue in adults.

Assessment and management of cancer-related fatigue in adults. Fatigue is one of the most prevalent and distressing symptoms of cancer, and is a common side-effect of many of the treatments available for the management of malignant disease. We critically assess the evidence for cancer-related fatigue and its treatment in adults. Little is known about the cause and mechanisms of fatigue, and research into methods of alleviating the condition has focused on treatment for anaemia and behavioural (...) interventions, such as exercise, both of which are effective in reducing fatigue. Although research into the condition has increased considerably in the past decade, important gaps in knowledge remain.

Lancet2003

192. Psychological treatment of patients with chronic toxic encephalopathy: lessons from studies of chronic fatigue and whiplash

Psychological treatment of patients with chronic toxic encephalopathy: lessons from studies of chronic fatigue and whiplash Psychological treatment of patients with chronic toxic encephalopathy: lessons from studies of chronic fatigue and whiplash Psychological treatment of patients with chronic toxic encephalopathy: lessons from studies of chronic fatigue and whiplash van Hout M S, Wekking E M, Berg I J, Deelman B G CRD summary This review assessed the effectiveness of psychologically based (...) treatments for 'chronic toxic encephalopathy' (CTE), chronic whiplash-associated disorder and chronic fatigue syndrome. The authors concluded that cognitive-behaviour therapy plus graded activity may improve symptoms of CTE. The conclusions were based on a small number of studies and study quality was not systematically assessed, so the conclusions may not be reliable. Authors' objectives To assess the effect of (neuro)psychological treatments for chronic toxic encephalopathy (CTE) and the comparable

DARE.2003

193. Iron supplementation for unexplained fatigue in non-anaemic women: double blind randomised placebo controlled trial.

Iron supplementation for unexplained fatigue in non-anaemic women: double blind randomised placebo controlled trial. 12763985 2003 05 23 2003 06 16 2014 11 20 1756-1833 326 7399 2003 May 24 BMJ (Clinical research ed.) BMJ Iron supplementation for unexplained fatigue in non-anaemic women: double blind randomised placebo controlled trial. 1124 To determine the subjective response to iron therapy in non-anaemic women with unexplained fatigue. Double blind randomised placebo controlled trial (...) . Academic primary care centre and eight general practices in western Switzerland. 144 women aged 18 to 55, assigned to either oral ferrous sulphate (80 mg/day of elemental iron daily; n=75) or placebo (n=69) for four weeks. Level of fatigue, measured by a 10 point visual analogue scale. 136 (94%) women completed the study. Most had a low serum ferritin concentration; fatigue, depression

BMJ2003 Full Text: Link to full Text with Trip Pro

194. Sleep loss and fatigue in residency training: a reappraisal.

Sleep loss and fatigue in residency training: a reappraisal. Reduced sleep time is commonplace for many interns and residents. Recent studies, however, suggest that sleep loss and fatigue result in significant neurobehavioral impairments in healthy young adults. We reviewed studies addressing the effects of sleep loss on cognition, performance, and health in surgical and nonsurgical residents. We describe the effectiveness of countermeasures for sleepiness, including recent work-hour (...) restrictions. A more complete understanding of the issues of sleep loss during residency training can inform innovative strategies to minimize the effects of sleepiness and fatigue on patient care and resident safety.

JAMA2002

195. Beta-blocker therapy and symptoms of depression, fatigue, and sexual dysfunction.

Beta-blocker therapy and symptoms of depression, fatigue, and sexual dysfunction. CONTEXT: beta-Blocker therapy remains substantially underused in cardiac patients despite its proven mortality benefits. Reluctance to prescribe these agents may derive from concerns about their association with symptoms of depression, fatigue, and sexual dysfunction. OBJECTIVE: To determine the association of beta-blockers with depressive symptoms, fatigue, and sexual dysfunction by performing a quantitative (...) of trials in the review were: random allocation of study treatments, placebo control, noncrossover design, enrollment of at least 100 patients, and a minimum of 6 months of follow-up. The initial search produced 475 articles, 42 of which met these criteria. Fifteen of these trials reported on depressive symptoms, fatigue, or sexual dysfunction and were selected for inclusion. DATA EXTRACTION: For each trial, 1 author abstracted the frequency of adverse events in the beta-blocker and placebo groups

JAMA2002

196. Management of cancer symptoms: pain, depression and fatigue

Management of cancer symptoms: pain, depression and fatigue Management of cancer symptoms: pain, depression and fatigue Management of cancer symptoms: pain, depression and fatigue Carr D, Goudas L, Lawrence D Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Carr D, Goudas L, Lawrence D. Management of cancer symptoms: pain, depression (...) and fatigue. Rockville: Agency for Healthcare Research and Quality (AHRQ). Evidence Report/Technology Assessment No. 61. 2002 Authors' objectives Despite dramatic advances in cancer biology and a widening array of treatment options, cancer continues to cause devastating suffering not only in the hundreds of thousands of patients who die of it each year in the United States, but also in some patients who are successfully treated and become cancer survivors. This report was produced on request from

Health Technology Assessment (HTA) Database.2002

197. Systematic review of the current literature related to disability and chronic fatigue syndrome

Systematic review of the current literature related to disability and chronic fatigue syndrome Systematic review of the current literature related to disability and chronic fatigue syndrome Systematic review of the current literature related to disability and chronic fatigue syndrome Ross S D, Levine C, Ganz N, Frame D, Estok R, Stone L, Ludensky V Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality (...) of this assessment has been made for the HTA database. Citation Ross S D, Levine C, Ganz N, Frame D, Estok R, Stone L, Ludensky V. Systematic review of the current literature related to disability and chronic fatigue syndrome. Rockville: Agency for Healthcare Research and Quality (AHRQ). Evidence Report/Technology Assessment No. 66. 2002 Authors' objectives The objective of this evidence report was to perform a systematic review of the published literature to provide the Social Security Administration (SSA

Health Technology Assessment (HTA) Database.2002

198. The effectiveness of interventions used in the treatment/management of chronic fatigue syndrome and/or myalgic encephalomyelitis in adults and children

The effectiveness of interventions used in the treatment/management of chronic fatigue syndrome and/or myalgic encephalomyelitis in adults and children The effectiveness of interventions used in the treatment/management of chronic fatigue syndrome and/or myalgic encephalomyelitis in adults and children The effectiveness of interventions used in the treatment/management of chronic fatigue syndrome and/or myalgic encephalomyelitis in adults and children NHS Centre for Reviews and Dissemination (...) Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation NHS Centre for Reviews and Dissemination. The effectiveness of interventions used in the treatment/management of chronic fatigue syndrome and/or myalgic encephalomyelitis in adults and children. University of York. CRD Report 22. 2002 Authors' objectives The aim of this study was to assess

Health Technology Assessment (HTA) Database.2002

199. Beta-blocker therapy and symptoms of depression, fatigue, and sexual dysfunction

Beta-blocker therapy and symptoms of depression, fatigue, and sexual dysfunction Beta-blocker therapy and symptoms of depression, fatigue, and sexual dysfunction Beta-blocker therapy and symptoms of depression, fatigue, and sexual dysfunction Ko D T, Hebert P R, Coffey C S, Sedrakyan A, Curtis J P, Krumholz H M Authors' objectives To determine the association of beta-blockers with depressive symptoms, fatigue and sexual dysfunction by performing a quantitative review of randomised trials (...) -blockers and had a diagnosis of myocardial infarction, hypertension or congestive heart failure. Outcomes assessed in the review The outcomes to be assessed were the frequency of depressive symptoms, fatigue or sexual dysfunction. The withdrawal of medication for depressive symptoms, fatigue or sexual dysfunction was also assessed. How were decisions on the relevance of primary studies made? The authors do not state how the papers were selected for the review, or how many of the reviewers performed

DARE.2002

200. Systematic review of the current literature related to disability and chronic fatigue syndrome

Systematic review of the current literature related to disability and chronic fatigue syndrome Systematic review of the current literature related to disability and chronic fatigue syndrome Systematic review of the current literature related to disability and chronic fatigue syndrome Ganz N, Frame D, Estok R, Stone L, Ludensky V Authors' objectives The overall review objective was to assess how best to measure, monitor and treat disability in patients with chronic fatigue syndrome (CFS). This (...) structured abstract focuses on the sub-question in the review: What is the evidence that in individuals with CFS, treatments are effective in restoring the ability to work? Searching MEDLINE, Current Contents, the Cochrane Library and PsycINFO were searched (January 1988 to November 2001) for relevant studies; the search terms were reported. The studies were restricted to those published in English and conducted in the USA, Canada, Australia or Western Europe. Study selection Study designs of evaluations

DARE.2002