Latest & greatest articles for escitalopram

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on escitalopram or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on escitalopram and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for escitalopram

1. Escitalopram

Escitalopram Top results for escitalopram - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing (...) the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for escitalopram The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines

Trip Latest and Greatest2018

2. Effect of Escitalopram vs Placebo Treatment for Depression on Long-term Cardiac Outcomes in Patients With Acute Coronary Syndrome: A Randomized Clinical Trial.

Effect of Escitalopram vs Placebo Treatment for Depression on Long-term Cardiac Outcomes in Patients With Acute Coronary Syndrome: A Randomized Clinical Trial. Importance: Depression has been associated with poorer medical outcomes in acute coronary syndrome (ACS), but there are few data on the effects of antidepressant treatment on long-term prognosis. Objective: To investigate the effect on long-term major adverse cardiac events (MACE) of escitalopram treatment of depression in patients (...) with recent ACS. Design, Setting, and Participants: Randomized, double-blind, placebo-controlled trial conducted among 300 patients with recent ACS and depression enrolled from May 2007 to March 2013, with follow-up completed in June 2017, at Chonnam National University Hospital, Gwangju, South Korea. Interventions: Patients were randomly assigned to receive either escitalopram in flexible dosages of 5, 10, 15, or 20 mg/d (n = 149) or matched placebo (n = 151) for 24 weeks. Main Outcomes and Measures

JAMA2018

3. Randomised controlled trial of escitalopram for cervical dystonia with dystonic jerks/tremor

Randomised controlled trial of escitalopram for cervical dystonia with dystonic jerks/tremor 29326295 2018 01 12 1468-330X 2018 Jan 11 Journal of neurology, neurosurgery, and psychiatry J. Neurol. Neurosurg. Psychiatry Randomised controlled trial of escitalopram for cervical dystonia with dystonic jerks/tremor. jnnp-2017-317352 10.1136/jnnp-2017-317352 Trials for additional or alternative treatments for cervical dystonia (CD) are scarce since the introduction of botulinum neurotoxin (BoNT). We (...) performed the first trial to investigate whether dystonic jerks/tremor in patients with CD respond to the selective serotonin reuptake inhibitor (SSRI) escitalopram. In a randomised, double-blind, crossover trial, patients with CD received escitalopram and placebo for 6 weeks. Treatment with BoNT was continued, and scores on rating scales regarding dystonia, psychiatric symptoms and quality of life (QoL) were compared. Primary endpoint was the proportion of patients that improved at least one point

EvidenceUpdates2018

4. Depressed patients with heart failure may not improve with escitalopram

Depressed patients with heart failure may not improve with escitalopram Depressed patients with heart failure may not improve with escitalopram Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Depressed patients with heart failure may not improve with escitalopram View/ Open Date 2017-07 Format Metadata Abstract Bottom (...) line: Escitalopram does not decrease mortality, rehospitalization rates, or depression symptoms among depressed patients with heart failure. This conclusion may not apply to all depressed patients and the study population was not large enough to definitively rule out a benefit in depression symptoms. URI Part of Citation Evidence-based practice 20, no. 7 (2017): E13 Collections hosted by hosted by

Evidence Based Practice 2017

5. Trial of Electrical Direct-Current Therapy versus Escitalopram for Depression.

Trial of Electrical Direct-Current Therapy versus Escitalopram for Depression. BACKGROUND: We compared transcranial direct-current stimulation (tDCS) with a selective serotonin-reuptake inhibitor for the treatment of depression. METHODS: In a single-center, double-blind, noninferiority trial involving adults with unipolar depression, we randomly assigned patients to receive tDCS plus oral placebo, sham tDCS plus escitalopram, or sham tDCS plus oral placebo. The tDCS was administered in 30 (...) -minute, 2-mA prefrontal stimulation sessions for 15 consecutive weekdays, followed by 7 weekly treatments. Escitalopram was given at a dose of 10 mg per day for 3 weeks and 20 mg per day thereafter. The primary outcome measure was the change in the 17-item Hamilton Depression Rating Scale (HDRS-17) score (range, 0 to 52, with higher scores indicating more depression). Noninferiority of tDCS versus escitalopram was defined by a lower boundary of the confidence interval for the difference

NEJM2017

6. Citalopram and escitalopram: opt for other SSRI antidepressants

Citalopram and escitalopram: opt for other SSRI antidepressants Prescrire IN ENGLISH - Spotlight ''Citalopram and escitalopram: opt for other SSRI antidepressants'', 1 September 2016 {1} {1} {1} | | > > > Citalopram and escitalopram: opt for other SSRI antidepressants Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight Citalopram and escitalopram: opt (...) for other SSRI antidepressants As of early 2016, studies point to the same overall conclusion: that citalopram and its derivative escitalopram expose patients to a higher risk of cardiac disorders than other SSRI antidepressants. Citalopram and escitalopram are selective serotonin reuptake inhibitors (SSRI). These two drugs are no more effective than other SSRI antidepressants, and their adverse effects profile is also very similar. In 2011 and 2012, the Food and Drug Administration (FDA) issued

Prescrire2016

7. Combining escitalopram and cognitive-behavioural therapy for social anxiety disorder: randomised controlled fMRI trial

Combining escitalopram and cognitive-behavioural therapy for social anxiety disorder: randomised controlled fMRI trial 27340112 2016 09 02 2016 09 02 1472-1465 209 3 2016 Sep The British journal of psychiatry : the journal of mental science Br J Psychiatry Combining escitalopram and cognitive-behavioural therapy for social anxiety disorder: randomised controlled fMRI trial. 229-35 10.1192/bjp.bp.115.175794 Selective serotonin reuptake inhibitors (SSRIs) and cognitive-behavioural therapy (CBT (...) ) are often used concomitantly to treat social anxiety disorder (SAD), but few studies have examined the effect of this combination. To evaluate whether adding escitalopram to internet-delivered CBT (ICBT) improves clinical outcome and alters brain reactivity and connectivity in SAD. Double-blind, randomised, placebo-controlled neuroimaging trial of ICBT combined either with escitalopram (n = 24) or placebo (n = 24), including a 15-month clinical follow-up (trial registration: ISRCTN24929928

EvidenceUpdates2016

8. Effect of Escitalopram on All-Cause Mortality and Hospitalization in Patients With Heart Failure and Depression: The MOOD-HF Randomized Clinical Trial.

Effect of Escitalopram on All-Cause Mortality and Hospitalization in Patients With Heart Failure and Depression: The MOOD-HF Randomized Clinical Trial. IMPORTANCE: Depression is frequent in patients with heart failure and is associated with adverse clinical outcomes. Long-term efficacy and safety of selective serotonin reuptake inhibitors in these patients are unknown. OBJECTIVE: To determine whether 24 months of treatment with escitalopram improves mortality, morbidity, and mood in patients (...) fraction (<45%) were screened for depression using the 9-item Patient Health Questionnaire. Patients with suspected depression were then invited to undergo a Structured Clinical Interview based on the Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) to establish the diagnosis. INTERVENTIONS: Patients were randomized 1:1 to receive escitalopram (10-20 mg) or matching placebo in addition to optimal heart failure therapy. Study duration was 24 months. MAIN OUTCOMES AND MEASURES

JAMA2016

9. Analgesic Effect of Perioperative Escitalopram in High Pain Catastrophizing Patients after Total Knee Arthroplasty: A Randomized, Double-blind, Placebo-controlled Trial

Analgesic Effect of Perioperative Escitalopram in High Pain Catastrophizing Patients after Total Knee Arthroplasty: A Randomized, Double-blind, Placebo-controlled Trial 25782644 2015 03 18 2015 06 24 2015 03 18 1528-1175 122 4 2015 Apr Anesthesiology Anesthesiology Analgesic effect of perioperative escitalopram in high pain catastrophizing patients after total knee arthroplasty: a randomized, double-blind, placebo-controlled trial. 884-94 10.1097/ALN.0000000000000597 Sufficient pain treatment (...) remains a challenge after total knee arthroplasty (TKA), especially in high pain catastrophizing patients. Serotonergic signaling may be involved in pain processing, but the effect of selective serotonin reuptake inhibitors on well-defined postoperative pain has not previously been investigated. The authors hypothesized that perioperative escitalopram would reduce pain after TKA in high pain catastrophizing patients. A total of 120 pain catastrophizing patients (selected using the pain catastrophizing

EvidenceUpdates2015

10. Escitalopram

Escitalopram USE OF ESCITALOPRAM IN PREGNANCY 0344 892 0909 USE OF ESCITALOPRAM IN PREGNANCY (Date of issue: January 2017 , Version: 2.2 ) This is a UKTIS monograph for use by health care professionals. For case-specific advice please contact UKTIS on 0344 892 0909. To report an exposure please download and complete a . Please encourage all women to complete an . A corresponding patient information leaflet on is available at . Summary Escitalopram is a selective serotonin reuptake inhibitor (...) (SSRI) used in the treatment of depression, panic disorder, with or without agoraphobia, generalised and social anxiety disorder, and obsessive-compulsive disorder. Although limited, data on the risk of congenital malformation following escitalopram use in early pregnancy are generally reassuring. The available studies provide no evidence of an increase in overall congenital malformation rate, and the majority of studies investigating specific cardiovascular malformations have failed to identify

UK Teratology Information Service2014

11. Effect of escitalopram on mental stress-induced myocardial ischemia: results of the REMIT trial.

Effect of escitalopram on mental stress-induced myocardial ischemia: results of the REMIT trial. IMPORTANCE: Mental stress can induce myocardial ischemia and also has been implicated in triggering cardiac events. However, pharmacological interventions aimed at reducing mental stress-induced myocardial ischemia (MSIMI) have not been well studied. OBJECTIVE: To examine the effects of 6 weeks of escitalopram treatment vs placebo on MSIMI and other psychological stress-related biophysiological (...) and emotional parameters. DESIGN, SETTING, AND PARTICIPANTS: The REMIT (Responses of Mental Stress Induced Myocardial Ischemia to Escitalopram Treatment) study, a randomized, double-blind, placebo-controlled trial of patients with clinically stable coronary heart disease and laboratory-diagnosed MSIMI. Enrollment occurred from July 24, 2007, through August 24, 2011, at a tertiary medical center. INTERVENTIONS: Eligible participants were randomized 1:1 to receive escitalopram (dose began at 5 mg/d

JAMA2013

12. Review: short-term benefit of escitalopram versus citalopram for depression uncertain, but big difference in French health insurance costs

Review: short-term benefit of escitalopram versus citalopram for depression uncertain, but big difference in French health insurance costs Review: short-term benefit of escitalopram versus citalopram for depression uncertain, but big difference in French health insurance costs | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional (...) accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: short-term benefit of escitalopram versus citalopram for depression uncertain, but big difference in French health insurance costs Article Text Therapeutics Review: short-term benefit of escitalopram versus citalopram

Evidence-Based Mental Health2013

13. Cost-effectiveness evaluation in Sweden of escitalopram compared with venlafaxine extended-release as first-line treatment in major depressive disorder

Cost-effectiveness evaluation in Sweden of escitalopram compared with venlafaxine extended-release as first-line treatment in major depressive disorder Cost-effectiveness evaluation in Sweden of escitalopram compared with venlafaxine extended-release as first-line treatment in major depressive disorder Cost-effectiveness evaluation in Sweden of escitalopram compared with venlafaxine extended-release as first-line treatment in major depressive disorder Nordstrom G, Danchenko N, Despiegel N (...) , Marteau F Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study investigated the cost-effectiveness of escitalopram compared with venlafaxine extended release, as first-line treatment for adults with major depressive disorder

NHS Economic Evaluation Database.2013

14. Effect of escitalopram on mental stress-induced myocardial ischemia: results of the REMIT trial.

Effect of escitalopram on mental stress-induced myocardial ischemia: results of the REMIT trial. 23695483 2013 05 22 2013 05 24 2016 12 15 1538-3598 309 20 2013 May 22 JAMA JAMA Effect of escitalopram on mental stress-induced myocardial ischemia: results of the REMIT trial. 2139-49 10.1001/jama.2013.5566 Mental stress can induce myocardial ischemia and also has been implicated in triggering cardiac events. However, pharmacological interventions aimed at reducing mental stress-induced myocardial (...) ischemia (MSIMI) have not been well studied. To examine the effects of 6 weeks of escitalopram treatment vs placebo on MSIMI and other psychological stress-related biophysiological and emotional parameters. The REMIT (Responses of Mental Stress Induced Myocardial Ischemia to Escitalopram Treatment) study, a randomized, double-blind, placebo-controlled trial of patients with clinically stable coronary heart disease and laboratory-diagnosed MSIMI. Enrollment occurred from July 24, 2007, through August 24

JAMA2013 Full Text: Link to full Text with Trip Pro

15. Sexual function in nondepressed women using escitalopram for vasomotor symptoms: a randomized controlled trial

Sexual function in nondepressed women using escitalopram for vasomotor symptoms: a randomized controlled trial 22353950 2012 02 22 2012 04 18 2016 10 19 1873-233X 119 3 2012 Mar Obstetrics and gynecology Obstet Gynecol Sexual function in nondepressed women using escitalopram for vasomotor symptoms: a randomized controlled trial. 527-38 10.1097/AOG.0b013e3182475fa4 To evaluate sexual function in midlife women using selective serotonin reuptake inhibitors for vasomotor symptoms (...) . Selective serotonin reuptake inhibitors effectively treat vasomotor symptoms but adversely affect sexual function in depressed populations. Information on sexual function in nondepressed midlife women using selective serotonin reuptake inhibitors for vasomotor symptoms is lacking; any treatments that might impair function are of concern. This was a randomized controlled trial comparing 8 weeks of escitalopram with placebo in women ages 40-62 years with 28 or more bothersome vasomotor symptoms per week. Change in Female Sexual

EvidenceUpdates2012 Full Text: Link to full Text with Trip Pro

16. Efficacy of escitalopram compared to citalopram: a meta-analysis

Efficacy of escitalopram compared to citalopram: a meta-analysis Efficacy of escitalopram compared to citalopram: a meta-analysis Efficacy of escitalopram compared to citalopram: a meta-analysis Montgomery S, Hansen T, Kasper S CRD summary The review concluded that there was a statistically and clinically significant benefit with escitalopram compared with citalopram in patients with major depressive disorder. The review appeared to have some methodological limitations, and the quality (...) of the included trials is uncertain; hence, caution is warranted when interpreting the authors’ conclusions. Authors' objectives To assess the clinical relevance of the relative antidepressant efficacy of escitalopram and citalopram for the treatment of major depressive disorder. Searching MEDLINE (1966 to June 2009), EMBASE (1998 to 2009) and The Cochrane Library (1980 to June 2009) were searched for articles in any language. Search terms were reported. Reference lists of retrieved studies were searched

DARE.2012

17. Citalopram and escitalopram: QT interval prolongation

Citalopram and escitalopram: QT interval prolongation Citalopram and escitalopram: QT interval prolongation Drug Safety Update - GOV.UK GOV.UK uses cookies to make the site simpler. Search Citalopram and escitalopram: QT interval prolongation From: Published: 12 December 2011 Therapeutic area: New maximum daily dose restrictions (including in elderly patients), contraindications, and warnings. Article date: December 2011 Citalopram, a racemic mixture of R and S citalopram (...) , is a selective serotonin reuptake inhibitor (SSRI) indicated for the treatment of major depressive disorder, panic disorder, and obsessive compulsive disorder. Escitalopram is the S enantiomer of citalopram indicated for major depressive episodes, panic disorder with or without agoraphobia, social anxiety disorder (social phobia), generalised anxiety disorder, and obsessive compulsive disorder. New data for QT prolongation with citalopram and escitalopram The potential for citalopram and escitalopram to cause QT interval prolongation

MHRA Drug Safety Update2011

18. Randomised controlled trial: Escitalopram reduced hot flashes in non-depressed perimenopausal and postmenopausal women

Randomised controlled trial: Escitalopram reduced hot flashes in non-depressed perimenopausal and postmenopausal women Escitalopram reduced hot flashes in non-depressed perimenopausal and postmenopausal women | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search (...) for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Escitalopram reduced hot flashes in non-depressed perimenopausal and postmenopausal women Article Text Therapeutics Randomised controlled trial Escitalopram reduced hot flashes in non-depressed perimenopausal and postmenopausal women Claudio N Soares 1 , 2 Statistics from Altmetric.com No Altmetric

Evidence-Based Medicine (Requires free registration)2011

19. Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial.

Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial. 21245182 2011 01 19 2011 01 24 2016 10 19 1538-3598 305 3 2011 Jan 19 JAMA JAMA Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial. 267-74 10.1001/jama.2010.2016 Concerns regarding the risks associated with estrogen and progesterone to manage menopausal symptoms have resulted in its declining use and increased interest in nonhormonal treatments (...) with demonstrated efficacy for hot flashes. To determine the efficacy and tolerability of 10 to 20 mg/d escitalopram, a selective serotonin reuptake inhibitor, in alleviating the frequency, severity, and bother of menopausal hot flashes. A multicenter, 8-week, randomized, double-blind, placebo-controlled, parallel group trial that enrolled 205 women (95 African American; 102 white; 8 other) between July 2009 and June 2010. Women received 10 to 20 mg/d of escitalopram or a matching placebo for 8 weeks. Primary

JAMA2011 Full Text: Link to full Text with Trip Pro

20. Is escitalopram really relevantly superior to citalopram in treatment of major depressive disorder? A meta-analysis of head-to-head randomized trials

Is escitalopram really relevantly superior to citalopram in treatment of major depressive disorder? A meta-analysis of head-to-head randomized trials Is escitalopram really relevantly superior to citalopram in treatment of major depressive disorder? A meta-analysis of head-to-head randomized trials Is escitalopram really relevantly superior to citalopram in treatment of major depressive disorder? A meta-analysis of head-to-head randomized trials Trkulja V CRD summary This review compared (...) the efficacy of equimolar doses of escitalopram and citalopram in patients with major depressive disorder. The author concluded that claims to the clinically relevant superiority of escitalopram over citalopram in the short-to-medium term were not supported. This conclusion reflected the variable evidence presented, but its reliability is unclear due to potential methodological shortcomings in the review process. Authors' objectives To compare the efficacy of equimolar escitalopram and citalopram

DARE.2010