Latest & greatest articles for epilepsy

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Top results for epilepsy

261. Pharmacological interventions for epilepsy in people with intellectual disabilities.

Pharmacological interventions for epilepsy in people with intellectual disabilities. BACKGROUND: The development of epilepsy in a person with intellectual disabilities is a common occurrence. In view of the fact that seizures in intellectually disabled people are often complex and refractory to treatment and that antiepileptic medication may have a profound effect upon behaviour in this patient group, it is evident that good quality randomised controlled trials are needed in this population (...) . OBJECTIVES: The aim of our study was to assess the data available from randomised controlled trials of antiepileptic drug interventions in people with epilepsy and intellectual disabilities. SEARCH STRATEGY: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2006, Issue 4), MEDLINE OVID (1966 to October 2006), PsychInfo OVID (1806 to October 2006) and EMBASE OVID (1980 to April 2005). SELECTION CRITERIA: Randomised controlled trials (RCTs) of pharmacological

Cochrane2007

262. Self-management education for adults with epilepsy.

Self-management education for adults with epilepsy. BACKGROUND: Self-management education has been shown to improve the quality of life of people with chronic illnesses. It has been suggested that self-management education may improve seizure control and other outcomes in people with epilepsy. OBJECTIVES: To review systematically the research literature on the effectiveness of self-management education in improving health outcomes for adults with epilepsy. SEARCH STRATEGY: We searched MEDLINE (...) (Ovid) (1966 to April 2005), EMBASE (Ovid) (1980 to April 2005), CINAHL (Dialog) (1980 to April 2005), PsycINFO (Dialog) (1887 to April 2005), and the Cochrane Epilepsy Group's Specialised Register (April 2005). We also handsearched Epilepsia and conference abstracts and proceedings. Experts in the field were contacted to identify any additional trials. We did not impose any language restriction. We re-ran the searches in February 2007 and added the identified references to the 'Studies awaiting

Cochrane2007

263. Self-management education for children with epilepsy.

Self-management education for children with epilepsy. BACKGROUND: Self-management education has been shown to improve the quality of life of children and young people with chronic illnesses. It has been suggested that self-management education may improve seizure control and other outcomes in children and young people with epilepsy. OBJECTIVES: To review systematically the research literature on the effectiveness of self-management education in improving health outcomes for children and young (...) people with epilepsy. SEARCH STRATEGY: We searched the Cochrane Epilepsy Group's Specialised Register (April 2007), MEDLINE (Ovid) (1966 to February 2007), EMBASE (Ovid) (1980 to February 2007), CINAHL (Dialog) (1980 to February 2007), and PsycINFO (Dialog) (1887 to February 2007). We also handsearched Epilepsia and conference abstracts and proceedings. Experts in the field were contacted to identify any additional trials. No language restriction was imposed. SELECTION CRITERIA: Randomised trials

Cochrane2007

264. Epilepsy or a family history of epilepsy increases the risk of schizophrenia or schizophrenia-like psychosis

Epilepsy or a family history of epilepsy increases the risk of schizophrenia or schizophrenia-like psychosis Epilepsy or a family history of epilepsy increases the risk of schizophrenia or schizophrenia-like psychosis | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password (...) ? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Epilepsy or a family history of epilepsy increases the risk of schizophrenia or schizophrenia-like psychosis Article Text Aetiology Epilepsy or a family history of epilepsy increases the risk of schizophrenia or schizophrenia-like psychosis Statistics from Altmetric.com No Altmetric

Evidence-Based Mental Health2007

265. Therapeutic monitoring of antiepileptic drugs for epilepsy.

Therapeutic monitoring of antiepileptic drugs for epilepsy. BACKGROUND: The aim of drug treatment for epilepsy is to prevent seizures without causing adverse effects. To achieve this, drug dosages need to be individualised. Measuring antiepileptic drug levels in body fluids (therapeutic drug monitoring) is frequently used to optimise drug dosage for individual patients. OBJECTIVES: To review the evidence regarding the effects of therapeutic drug monitoring upon outcomes in epilepsy. SEARCH (...) STRATEGY: We searched the Cochrane Epilepsy Group Specialised Register (September 2006), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2005, Issue 4), MEDLINE (January 1966 to April 2005) and EMBASE (1974 to May 2005). No language restrictions were imposed. We checked the reference lists of retrieved articles for additional reports of relevant studies. SELECTION CRITERIA: Randomised controlled trials comparing the outcomes of antiepileptic drug monotherapy guided

Cochrane2007

266. Corticosteroids including ACTH for childhood epilepsy other than epileptic spasms.

Corticosteroids including ACTH for childhood epilepsy other than epileptic spasms. BACKGROUND: Epilepsy is a disorder with recurrent epileptic seizures. Corticosteroids have been used in the treatment of children with epilepsy and have significant adverse effects. Their efficacy and tolerability have not been not clearly established. OBJECTIVES: To determine the efficacy of corticosteroids in terms of seizure control, improvements in cognition and in quality of life and tolerability of steroids (...) compared to placebo or other antiepileptic drugs. SEARCH STRATEGY: We searched the following databases: The Cochrane Epilepsy Group Specialized Register (September 2006); Cochrane Central Register of Controlled Trials (CENTRAL)(The Cochrane Library Issue 2, 2006); MEDLINE (1966 - April 2004); EMBASE (1966 - December 2004); Database of Abstracts of Reviews of Effectiveness (DARE) (December 2004). We checked the reference lists of retrieved studies for additional reports of relevant studies. SELECTION

Cochrane2007

267. The cost-effectiveness of newer drugs as add-on therapy for children with focal epilepsies

The cost-effectiveness of newer drugs as add-on therapy for children with focal epilepsies The cost-effectiveness of newer drugs as add-on therapy for children with focal epilepsies The cost-effectiveness of newer drugs as add-on therapy for children with focal epilepsies Frew E J, Sandercock J, Whitehouse W P, Bryan S Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods (...) , the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The study considered the addition of newer anti-epileptic drugs (AEDs) as an add-on therapy following the failure of monotherapy with carbamazepine and sodium valproate. The newer AEDs studied were lamotrigine, gabapentin, topiramate and oxcarbazepine. Type of intervention Treatment. Economic study type Cost-effectiveness analysis and cost-utility analysis

NHS Economic Evaluation Database.2007

268. The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial

The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial Marson A G, Al (...) by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The authors assessed valproate, lamotrigine and topiramate. Drug dosages and preparations were used as the clinician would use them in everyday practice. Type of intervention Treatment. Economic study type Cost-utility analysis. Study population The study population comprised patients with suspected epilepsy. Patients were included if they "had a history of two or more clinically definite

NHS Economic Evaluation Database.2007

269. The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial

The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial (...) epilepsy: an unblinded randomised controlled trial Marson A G, Al-Kharusi A M, Alwaidh M, Appleton R, Baker G A, Chadwick D W, Cramp C, Cockerell O C, Cooper P N, Doughty J, Eaton B, Gamble C, Goulding P J, Howell S J, Hughes A, Jackson M, Jacoby A, Kellett M, Lawson G R, Leach J P, Nicolaides P, Roberts R, Shackley P, other members of the SANAD study group Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains

NHS Economic Evaluation Database.2007

270. The cost effectiveness of zonisamide as adjunctive therapy in adult partial seizure epilepsy

The cost effectiveness of zonisamide as adjunctive therapy in adult partial seizure epilepsy The cost effectiveness of zonisamide as adjunctive therapy in adult partial seizure epilepsy The cost effectiveness of zonisamide as adjunctive therapy in adult partial seizure epilepsy Spackman D E, Yeates A, Rentz A M, Hutton J Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods (...) , the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The study evaluated the cost-effectiveness of zonisamide as treatment for adults with uncontrolled partial epilepsy in Scotland. The authors concluded that zonisamide was a cost-effective treatment for adults with refractory partial epilepsy. The methodology of the study appears appropriate and, on the whole, was clearly reported. The authors' conclusions reflect

NHS Economic Evaluation Database.2007

271. A cost-effectiveness decision model for antiepileptic drug treatment in newly diagnosed epilepsy patients

A cost-effectiveness decision model for antiepileptic drug treatment in newly diagnosed epilepsy patients A cost-effectiveness decision model for antiepileptic drug treatment in newly diagnosed epilepsy patients A cost-effectiveness decision model for antiepileptic drug treatment in newly diagnosed epilepsy patients Knoester P D, Deckers C L, Termeer E H, Boendermaker A J, Kotsopoulos I A, de Krom M C, Keyser T, Renier W O, Hekster Y A, Severens H L Record Status This is a critical abstract (...) of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The study assessed the cost-effectiveness of six antiepileptic drugs for the treatment of newly diagnosed epilepsy patients, including carbamezepine (CBZ), lamotrigine (LTG) and valproate (VPA) as first- and second-line drugs. The study

NHS Economic Evaluation Database.2007

272. Usefulness of SPECT in epilepsy

Usefulness of SPECT in epilepsy Usefulness of SPECT in epilepsy Usefulness of SPECT in epilepsy Colantonio L, Augustovski F, Pichon Riviere A Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Colantonio L, Augustovski F, Pichon Riviere A. Usefulness of SPECT in epilepsy. Buenos Aires: Institute for Clinical Effectiveness and Health Policy (...) (IECS). Informe Tecnico Breve No.32. 2007 Authors' objectives The objective of the report was to to analyze the use of SPECT for the pre-surgical evaluation of patients with epilepsy. Authors' conclusions In general, the quality of the studies associated with educational treatment programs for autistic children are methodologically poor and Floor Time therapy is not an exception. However, it seems that there is a certain degree of benefit from these interventions. There is not enough evidence

Health Technology Assessment (HTA) Database.2007

273. The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial.

The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial. 17382827 2007 03 26 2007 04 05 2017 02 19 1474-547X 369 9566 2007 Mar 24 Lancet (London, England) Lancet The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded randomised controlled trial. 1000-15 Carbamazepine (...) Alessandra A Williamson Paula R PR SANAD Study group eng ISRCTN ISRCTN38354748 HTA/95/13/01 Department of Health United Kingdom HTA_485 Department of Health United Kingdom Comparative Study Journal Article Multicenter Study Randomized Controlled Trial Research Support, Non-U.S. Gov't England Lancet 2985213R 0140-6736 0 Anticonvulsants AIM IM Lancet. 2007 Mar 24;369(9566):970-1 17382806 Epilepsy Curr. 2007 Sep-Oct;7(5):125-7 17998970 Rev Neurol Dis. 2008 Winter;5(1):36-7 18418324 ACP J Club. 2007 Nov-Dec

Lancet2007 Full Text: Link to full Text with Trip Pro

274. The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial.

The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. 17382828 2007 03 26 2007 04 05 2016 12 28 1474-547X 369 9566 2007 Mar 24 Lancet (London, England) Lancet The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. 1016-26 Valproate is widely accepted as a drug of first choice (...) . For time to treatment failure, valproate was significantly better than topiramate (hazard ratio 1.57 [95% CI 1.19-2.08]), but there was no significant difference between valproate and lamotrigine (1.25 [0.94-1.68]). For patients with an idiopathic generalised epilepsy, valproate was significantly better than both lamotrigine (1.55 [1.07-2.24] and topiramate (1.89 [1.32-2.70]). For time to 12-month remission valproate was significantly better than lamotrigine overall (0.76 [0.62-0.94

Lancet2007 Full Text: Link to full Text with Trip Pro

275. Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial.

Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial. 17145735 2007 06 08 2007 06 18 2016 12 15 1756-1833 334 7605 2007 Jun 09 BMJ (Clinical research ed.) BMJ Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial. 1207 To compare the behavioural side effects associated with two commonly used antiepilepsy drugs-phenobarbital and carbamazepine-in children in Bangladesh. Prospective randomised controlled (...) group and 39 in the carbamazepine group had no seizures in 74 and 102 days after randomisation, respectively. Ten children had increased behavioural problems, which were unacceptable in four (one in the phenobarbital group and three in the carbamazepine group). Independent t tests, however, showed no difference between the two trial drugs. There was no excess in behavioural side effects with phenobarbital in children with epilepsy in a country with limited resources. Trial registration NCT00381537

BMJ2007 Full Text: Link to full Text with Trip Pro

276. Acupuncture for epilepsy.

Acupuncture for epilepsy. BACKGROUND: Seizures are poorly controlled in many people with epilepsy despite adequate current antiepileptic treatments. There is increasing interest in alternative therapies such as acupuncture; however, it remains unclear whether the existing evidence is rigorous enough to support the use of acupuncture. OBJECTIVES: To determine the effectiveness and safety of acupuncture in people with epilepsy. SEARCH STRATEGY: We searched the Cochrane Epilepsy Group's (...) . SELECTION CRITERIA: Randomised controlled trials evaluating any form of acupuncture involving people of any age with any type of epilepsy were included. Trials included were those comparing acupuncture with placebo, sham or no treatment; or comparing acupuncture plus other treatments with the same other treatments. Trials that only compared different acupuncture methods or compared acupuncture alone with other treatments were excluded. DATA COLLECTION AND ANALYSIS: Two review authors independently

Cochrane2006

277. The clinical effectiveness and cost-effectiveness of newer drugs for children with epilepsy. A systematic review

The clinical effectiveness and cost-effectiveness of newer drugs for children with epilepsy. A systematic review The clinical effectiveness and cost-effectiveness of newer drugs for children with epilepsy. A systematic review Journals Library An error has occurred in processing the XML document An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation

NIHR HTA programme2006

278. Adult epilepsy.

Adult epilepsy. The epilepsies are one of the most common serious brain disorders, can occur at all ages, and have many possible presentations and causes. Although incidence in childhood has fallen over the past three decades in developed countries, this reduction is matched by an increase in elderly people. Monogenic Mendelian epilepsies are rare. A clinical syndrome often has multiple possible genetic causes, and conversely, different mutations in one gene can lead to various epileptic (...) syndromes. Most common epilepsies, however, are probably complex traits with environmental effects acting on inherited susceptibility, mediated by common variation in particular genes. Diagnosis of epilepsy remains clinical, and neurophysiological investigations assist with diagnosis of the syndrome. Brain imaging is making great progress in identifying the structural and functional causes and consequences of the epilepsies. Current antiepileptic drugs suppress seizures without influencing

Lancet2006

279. Recessive symptomatic focal epilepsy and mutant contactin-associated protein-like 2.

Recessive symptomatic focal epilepsy and mutant contactin-associated protein-like 2. Contactin-associated protein-like 2 (CASPR2) is encoded by CNTNAP2 and clusters voltage-gated potassium channels (K(v)1.1) at the nodes of Ranvier. We report a homozygous mutation of CNTNAP2 in Old Order Amish children with cortical dysplasia, focal epilepsy, relative macrocephaly, and diminished deep-tendon reflexes. Intractable focal seizures began in early childhood, after which language regression

NEJM2006

280. A systematic review of the effectiveness and cost-effectiveness of neuroimaging assessments used to visualise the seizure focus in people with refractory epilepsy being considered for surgery

A systematic review of the effectiveness and cost-effectiveness of neuroimaging assessments used to visualise the seizure focus in people with refractory epilepsy being considered for surgery A systematic review of the effectiveness and cost-effectiveness of neuroimaging assessments used to visualise the seizure focus in people with refractory epilepsy being considered for surgery Journals Library An error has occurred in processing the XML document An error occurred retrieving content

NIHR HTA programme2006