Latest & greatest articles for elderly

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Top results for elderly

101. Perampanel (Fycompa) - for the adjunctive treatment of primary generalised tonic-clonic seizures in adult and adolescent patients from 12 years of age with idiopathic generalised epilepsy.

Perampanel (Fycompa) - for the adjunctive treatment of primary generalised tonic-clonic seizures in adult and adolescent patients from 12 years of age with idiopathic generalised epilepsy. Published 12 August 2019 www.scottishmedicines.org.uk Statement of advice SMC2218 perampanel 0.5mg/mL oral suspension (Fycompa®) Eisai Ltd 5 July 2019 Advice context: No part of this advice may be used without the whole of the advice being quoted in full. This advice represents the view of the Scottish (...) with the patient and/or guardian or carer. Chairman Scottish Medicines Consortium ADVICE: in the absence of a submission from the holder of the marketing authorisation perampanel (Fycompa®) is not recommended for use within NHSScotland. Indication under review: for the adjunctive treatment of primary generalised tonic-clonic seizures in adult and adolescent patients from 12 years of age with idiopathic generalised epilepsy. The holder of the marketing authorisation has not made a submission to SMC regarding

2019 Scottish Medicines Consortium

102. MMR catch-up for 10 to 11 year old children: information for GPs

MMR catch-up for 10 to 11 year old children: information for GPs MMR catch-up for 10 to 11 year old children: information for GPs - GOV.UK GOV.UK uses cookies to make the site simpler. Accept cookies You’ve accepted all cookies. You can at any time. Hide Search Promotional material MMR catch-up for 10 to 11 year old children: information for GPs Information to support GP practices to carry out the MMR catch-up programme. Published 23 August 2019 From: Documents Ref: Public Health England

2019 Public Health England

103. Impact of community based screening for hypertension on blood pressure after two years: regression discontinuity analysis in a national cohort of older adults in China. Full Text available with Trip Pro

Impact of community based screening for hypertension on blood pressure after two years: regression discontinuity analysis in a national cohort of older adults in China. To estimate the causal impact of community based blood pressure screening on subsequent blood pressure levels among older adults in China.Regression discontinuity analysis using data from a national cohort study.2011-12 and 2014 waves of the Chinese Longitudinal Healthy Longevity Survey, a national cohort of older adults (...) in China.3899 older adults who had previously undiagnosed hypertension.Community based hypertension screening among older adults in 2011-12.Blood pressure two years after initial screening.The intervention reduced systolic blood pressure: -6.3 mm Hg in the model without covariates (95% confidence interval -11.2 to -1.3) and -8.3 mm Hg (-13.6 to -3.1) in the model that adjusts additionally for demographic, social, and behavioural covariates. The impact on diastolic blood pressure was smaller and non

2019 BMJ

104. Framework for Decision-making for Older Adults with Multiple Chronic Conditions: Action Steps for the AGS Guiding Principles on the Care of Older Adults with Multimorbidity

with Multiple Chronic Condit PRODUCT DETAILS × PIN Subscriprion Validating... Product Titile : Framework for Decision-making for Older Adults with Multiple Chronic Conditions: Action Steps for the AGS Guiding Principles on the Care of Older Adults with Multimorbidity Enter PIN * × PIN Subscriprion Subscription is completed successfully. Click OK button to go to MyLibrary page. Product Type : Guidelines, Recommendations & Position Statements Language : ENGLISH Publisher : American Geriatrics Society Year (...) Framework for Decision-making for Older Adults with Multiple Chronic Conditions: Action Steps for the AGS Guiding Principles on the Care of Older Adults with Multimorbidity Framework for Decision-making for Older Adults with Multiple Chronic Conditions: Action Steps for the AGS Guiding Principles on the Care of Older Adults with Multimorbidity Logging In... × Welcome to GeriatricsCareOnline! AGS or ADGAP MEMBER Attention AGS Members! As an AGS Member, you already have an account automatically

2019 American Geriatrics Society

105. American Geriatrics Society Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults

released its latest update to one of geriatrics’ most frequently cited reference tools: The AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults. With more than 90% of older people using at least one prescription and more than 66% using three or more in any given month, the AGS Beers Criteria® plays a vital role in helping health professionals, older adults, and caregivers work together to ensure medications are appropriate. DIGITAL : × Best Value To get the most for your (...) American Geriatrics Society Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults American Geriatrics Society Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults Logging In... × Welcome to GeriatricsCareOnline! AGS or ADGAP MEMBER Attention AGS Members! As an AGS Member, you already have an account automatically set up on GeriatricsCareOnline.org. Your username and password are the same that you use to log onto MyAGS. (If you do

2019 American Geriatrics Society

106. Comparison of Heart Rate Blood Pressure Product Versus Age-Predicted Maximum Heart Rate as Predictors of Cardiovascular Events During Exercise Stress Echocardiography (Abstract)

Comparison of Heart Rate Blood Pressure Product Versus Age-Predicted Maximum Heart Rate as Predictors of Cardiovascular Events During Exercise Stress Echocardiography Exercise stress echocardiograms (ESEs) are a functional cardiovascular (CV) test typically used for the investigation of coronary artery disease. ESEs are often terminated at a predetermined age-predicted maximum heart rate (APMHR) to facilitate timely acquisition of ultrasound images at peak exercise. Although an APMHR of 85

2019 EvidenceUpdates

107. Effect of Vitamin K2 on Postural Sway in Older People Who Fall: A Randomized Controlled Trial Full Text available with Trip Pro

of sway or secondary outcomes. Costs were higher in both vitamin K2 arms than in the placebo arm.Oral vitamin K2 supplementation did not improve postural sway or physical function in older people at risk of falls. J Am Geriatr Soc 67:2102-2107, 2019.© 2019 The Authors. Journal of the American Geriatrics Society published by Wiley Periodicals, Inc. on behalf of The American Geriatrics Society. (...) Effect of Vitamin K2 on Postural Sway in Older People Who Fall: A Randomized Controlled Trial Vitamin K is thought to be involved in both bone health and maintenance of neuromuscular function. We tested the effect of vitamin K2 supplementation on postural sway, falls, healthcare costs, and indices of physical function in older people at risk of falls.Parallel-group double-blind randomized placebo-controlled trial.Fourteen primary care practices in Scotland, UK.A total of 95 community-dwelling

2019 EvidenceUpdates

108. Ethnic and socioeconomic variation in cause-specific preterm infant mortality by gestational age at birth: national cohort study Full Text available with Trip Pro

Ethnic and socioeconomic variation in cause-specific preterm infant mortality by gestational age at birth: national cohort study To describe ethnic and socioeconomic variation in cause-specific infant mortality of preterm babies by gestational age at birth.National birth cohort study.England and Wales 2006-2012.Singleton live births at 24-36 completed weeks' gestation (n=256 142).Adjusted rate ratios for death in infancy by cause (three groups), within categories of gestational age at birth (24

2019 EvidenceUpdates

109. A Practical Two-Stage Frailty Assessment for Older Adults Undergoing Aortic Valve Replacement (Abstract)

A Practical Two-Stage Frailty Assessment for Older Adults Undergoing Aortic Valve Replacement Despite evidence, frailty is not routinely assessed before cardiac surgery. We compared five brief frailty tests for predicting poor outcomes after aortic valve replacement and evaluated a strategy of performing comprehensive geriatric assessment (CGA) in screen-positive patients.Prospective cohort study.A single academic center.Patients undergoing surgical aortic valve replacement (SAVR) (n = 91; mean (...) CGA may be a practical strategy to identify older patients at high risk for mortality and poor recovery after SAVR and TAVR in whom individualized care management should be considered. J Am Geriatr Soc 67:2031-2037, 2019.© 2019 The American Geriatrics Society.

2019 EvidenceUpdates

110. Effects of Tai Chi on Lower Limb Proprioception in Adults Aged Over 55: A Systematic Review and Meta-Analysis (Abstract)

Effects of Tai Chi on Lower Limb Proprioception in Adults Aged Over 55: A Systematic Review and Meta-Analysis To summarize and critically evaluate the effects of Tai Chi on lower limb proprioception in adults older than 55.Seven databases (Scopus, PubMed, Web of Science, SPORTDiscus, Cochrane Library, Wanfang, CNKI) were searched from inception until April 14, 2018.Eleven randomized controlled trials were included for meta-analysis.Two independent reviewers screened potentially relevant studies (...) proprioception in adults older than 55. More robust multicenter studies including oldest-old participants, with longer follow-ups and validated outcome measures, are needed before a definitive conclusion is drawn.Copyright © 2018 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

2019 EvidenceUpdates

111. Frailty assessment in older adults undergoing interventions for peripheral arterial disease (Abstract)

Frailty assessment in older adults undergoing interventions for peripheral arterial disease Frailty is a multidimensional syndrome that influences postoperative morbidity and mortality after vascular procedures; however, its integration in clinical practice has been limited, given the lack of consensus on how to measure it. This study sought to compare the incremental predictive value of six different nonphysical performance frailty scales to predict poor outcomes after interventions (...) with a mean age of 70 years. Depending on the scale used, the prevalence of frailty ranged from 16% to 70%. Frailty as measured by the GFI (adjusted odds ratio, 1.76; 95% confidence interval, 1.14-2.72) and mEFT (adjusted odds ratio, 2.71; 95% confidence interval, 1.29-5.73) predicted mortality and worsening disability at 12 months after interventions for PAD. Furthermore, there was statistically significant C-statistic, Bayesian information criterion, and integrated discrimination improvement when

2019 EvidenceUpdates

112. Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults Full Text available with Trip Pro

Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults To assess adverse effects of pharmacologic antidepressants for treatment of major depressive disorder (MDD) in adults 65 years of age or older.Systematic review and meta-analysis.Specialist or generalist outpatient setting, rehabilitation facility, and nursing facilities.Persons 65 years and older with MDD.Selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs (...) to a statistically similar frequency of overall adverse events vs placebo (moderate strength of evidence [SOE]), but SNRIs caused more overall adverse events vs placebo (high SOE) during the acute treatment phase. Both SSRIs and SNRIs led to more study withdrawals due to adverse events vs placebo (SSRIs low SOE; SNRIs moderate SOE). Duloxetine led to a more falls vs placebo (moderate SOE) during 24 weeks of acute and continuation treatment of MDD.In patients 65 years of age or older with MDD, treatment

2019 EvidenceUpdates

113. Systematic Review for the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines Full Text available with Trip Pro

Systematic Review for the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines The 2013 American College of Cardiology/American Heart Association guidelines for the treatment of blood cholesterol found little evidence to support the use of nonstatin lipid-modifying medications to reduce atherosclerotic cardiovascular

2019 EvidenceUpdates

114. Consequences of applying the new EWGSOP2 guideline instead of the former EWGSOP guideline for sarcopenia case finding in older patients (Abstract)

Consequences of applying the new EWGSOP2 guideline instead of the former EWGSOP guideline for sarcopenia case finding in older patients we examined the consequences of applying the new EWGSOP2 algorithm for sarcopenia screening instead of the former EWGSOP algorithm (EWGSOP1) in geriatric inpatients.the dataset of our formerly published Sarcopenia in Geriatric Elderly (SAGE) study includes 144 geriatric inpatients (86 women, 58 men, mean age 80.7±5.6 years) with measurements of gait speed (...) (0.0%) were newly diagnosed.there is a substantial mismatch in sarcopenia case finding according to EWGSOP1 and EWGSOP2. The overall prevalence and the number of men diagnosed with sarcopenia are significantly lower in EWGSOP2. While the absolute number of women identified as sarcopenic remains relatively constant, the overlap of individual cases between the two definitions is low.© The Author(s) 2019. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights

2019 EvidenceUpdates

115. Systematic review and updated meta-analysis of the use of drug-coated balloon angioplasty versus plain old balloon angioplasty for femoropopliteal arterial disease (Abstract)

Systematic review and updated meta-analysis of the use of drug-coated balloon angioplasty versus plain old balloon angioplasty for femoropopliteal arterial disease An endovascular-first approach is usually recommended in femoropopliteal occlusive disease. However, despite high technical success, plain old balloon angioplasty (POBA) is burdened with high restenosis rates. To reduce this phenomenon, local delivery of drugs has been proposed by way of drug-coated balloons (DCBs). Our goal

2019 EvidenceUpdates

116. Social skills training for attention deficit hyperactivity disorder (ADHD) in children aged 5 to 18 years. (Abstract)

Social skills training for attention deficit hyperactivity disorder (ADHD) in children aged 5 to 18 years. Attention deficit hyperactivity disorder (ADHD) in children is associated with hyperactivity and impulsivity, attention problems, and difficulties with social interactions. Pharmacological treatment may alleviate the symptoms of ADHD but this rarely solves difficulties with social interactions. Children with ADHD may benefit from interventions designed to improve their social skills. We (...) in accordance with the Cochrane Handbook for Systematic Reviews of Intervention. We performed the analyses using Review Manager 5 software and Trial Sequential Analysis. We assessed bias according to domains for systematic errors. We assessed the certainty of the evidence with the GRADE approach.We included 25 randomised clinical trials described in 45 reports. The trials included a total of 2690 participants aged between five and 17 years. In 17 trials, participants were also diagnosed with various

2019 Cochrane

117. Comparison of Universal Versus Age-Restricted Screening of Colorectal Tumors for Lynch Syndrome Using Mismatch Repair Immunohistochemistry: A Cohort Study. (Abstract)

Comparison of Universal Versus Age-Restricted Screening of Colorectal Tumors for Lynch Syndrome Using Mismatch Repair Immunohistochemistry: A Cohort Study. Guidelines recommend screening all patients with newly diagnosed colorectal cancer (CRC) for Lynch syndrome (LS). However, the efficiency of universal LS screening in elderly populations has not been well studied.To compare the performance of age-restricted and universal LS screening using reflex mismatch repair (MMR) immunohistochemistry (...) (IHC) of CRC tumors.Retrospective cohort study.A large, diverse, community-based health care system.3891 persons with newly diagnosed CRC who had LS screening between 2011 and 2016.Diagnostic yield of different LS screening strategies.Sixty-three LS cases (diagnostic yield, 1.62%) were identified by universal screening, with only 5 (7.9%) detected after age 70 years and 1 (1.6%) detected after age 80 years. When all patients with CRC who had universal screening were used as the denominator, 58 LS

2019 Annals of Internal Medicine

118. Pharmacotherapy for hypertension in adults 60 years or older. (Abstract)

of antihypertensive treatment for hypertension in this age group, as well as separately for people 60 to 79 years old and people 80 years or older.Primary objective• To quantify the effects of antihypertensive drug treatment as compared with placebo or no treatment on all-cause mortality in people 60 years and older with mild to moderate systolic or diastolic hypertensionSecondary objectives• To quantify the effects of antihypertensive drug treatment as compared with placebo or no treatment on cardiovascular (...) Pharmacotherapy for hypertension in adults 60 years or older. This is the second substantive update of this review. It was originally published in 1998 and was previously updated in 2009. Elevated blood pressure (known as 'hypertension') increases with age - most rapidly over age 60. Systolic hypertension is more strongly associated with cardiovascular disease than is diastolic hypertension, and it occurs more commonly in older people. It is important to know the benefits and harms

2019 Cochrane

119. Effect of a Home-Based Exercise Program on Subsequent Falls Among Community-Dwelling High-Risk Older Adults After a Fall: A Randomized Clinical Trial. Full Text available with Trip Pro

Effect of a Home-Based Exercise Program on Subsequent Falls Among Community-Dwelling High-Risk Older Adults After a Fall: A Randomized Clinical Trial. Whether exercise reduces subsequent falls in high-risk older adults who have already experienced a fall is unknown.To assess the effect of a home-based exercise program as a fall prevention strategy in older adults who were referred to a fall prevention clinic after an index fall.A 12-month, single-blind, randomized clinical trial conducted from (...) April 22, 2009, to June 5, 2018, among adults aged at least 70 years who had a fall within the past 12 months and were recruited from a fall prevention clinic.Participants were randomized to receive usual care plus a home-based strength and balance retraining exercise program delivered by a physical therapist (intervention group; n = 173) or usual care, consisting of fall prevention care provided by a geriatrician (usual care group; n = 172). Both were provided for 12 months.The primary outcome

2019 JAMA Controlled trial quality: predicted high

120. Productive healthy ageing: interventions for quality of life

isolation and loneliness 16 Malnutrition 18 Improving public mental health 21 Further information, tools and resources 23 References 25 A Menu of Interventions for Productive Healthy Ageing 4 Introduction The Menu of Interventions (MOIs) for productive health ageing is a guide that pharmacy teams working in different healthcare settings can use to support older people to improve the quality of their lives. It suggests opportunistic, evidence-based interventions that can help provide benefits for healthy (...) ageing. For example, supporting older people and their carers to prevent or reduce falls, increasing levels of physical activity, maintaining a healthy weight, reducing the risk of social isolation and loneliness, reducing the risk of dementia, supporting people diagnosed with dementia, delaying the progress of dementia and reducing the need for medicines. This is a menu of interventions that could be undertaken by pharmacy teams in the different sectors. It is recognised that not all pharmacy teams

2019 Public Health England