Latest & greatest articles for elderly

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Top results for elderly

1021. Giant cell arteritis, polymyalgia rheumatica, and late-onset rheumatoid arthritis: Can they be components of a single disease process in elderly patients? Full Text available with Trip Pro

Giant cell arteritis, polymyalgia rheumatica, and late-onset rheumatoid arthritis: Can they be components of a single disease process in elderly patients? To report two patients with giant cell arteritis (GCA) who developed rheumatoid arthritis (RA) and to review the literature in terms of coexistence of RA, GCA, and polymyalgia rheumatica (PMR).We conducted a comprehensive review of the English literature from 1980 to 2015 to analyze data on the coexistence of GCA and RA. The PubMed, Web (...) of Science, Proquest, and Ovid databases were searched for articles using the term RA combined with temporal arteritis, GCA, and PMR.We identified 17 other cases of coexistent GCA and RA reported in the English literature, together with our 2 cases (19 cases). They included 14 females and 5 males, with a mean age of 74.3 years (range: 57-84) at the time of GCA. The mean age at the time of RA diagnosis was 69.6 years (range 24-83). The average time elapsed between the onset of GCA and the development

2017 European journal of rheumatology

1022. The influence of sarcopenia in dropped head syndrome in older women Full Text available with Trip Pro

The influence of sarcopenia in dropped head syndrome in older women Age-related sarcopenia may cause physical dysfunction. We investigated the involvement of sarcopenia in dropped head syndrome (DHS).Our study subjects were ten elderly women with idiopathic DHS (mean age 75.1 years, range 55-89). Twenty age- and sex-matched volunteers (mean age 73.0, range 58-83) served as controls. We used a bioelectrical impedance analyzer (BIA) to analyze body composition, including appendicular skeletal

2017 Scoliosis and spinal disorders

1023. Hospitalizations of Brazilian children under fiver years old: a systematic review. Full Text available with Trip Pro

Hospitalizations of Brazilian children under fiver years old: a systematic review. to describe the causes of hospitalization of Brazilian children under five years old.this is a systematic review of articles published from 2008 to 2015, searched in the databases Medline and LILACS; selected studies were critically analyzed through a validated instrument.eleven articles were included, four of them are ecological and seven are cross-sectional studies; respiratory diseases (n=5), parasitic

2017 Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil

1024. Testosterone Treatment and Coronary Artery Plaque Volume in Older Men With Low Testosterone. Full Text available with Trip Pro

Testosterone Treatment and Coronary Artery Plaque Volume in Older Men With Low Testosterone. Recent studies have yielded conflicting results as to whether testosterone treatment increases cardiovascular risk.To test the hypothesis that testosterone treatment of older men with low testosterone slows progression of noncalcified coronary artery plaque volume.Double-blinded, placebo-controlled trial at 9 academic medical centers in the United States. The participants were 170 of 788 men aged 65 (...) years or older with an average of 2 serum testosterone levels lower than 275 ng/dL (82 men assigned to placebo, 88 to testosterone) and symptoms suggestive of hypogonadism who were enrolled in the Testosterone Trials between June 24, 2010, and June 9, 2014.Testosterone gel, with the dose adjusted to maintain the testosterone level in the normal range for young men, or placebo gel for 12 months.The primary outcome was noncalcified coronary artery plaque volume, as determined by coronary computed

2017 JAMA Controlled trial quality: predicted high

1025. Testosterone Treatment and Cognitive Function in Older Men With Low Testosterone and Age-Associated Memory Impairment. Full Text available with Trip Pro

Testosterone Treatment and Cognitive Function in Older Men With Low Testosterone and Age-Associated Memory Impairment. Most cognitive functions decline with age. Prior studies suggest that testosterone treatment may improve these functions.To determine if testosterone treatment compared with placebo is associated with improved verbal memory and other cognitive functions in older men with low testosterone and age-associated memory impairment (AAMI).The Testosterone Trials (TTrials) were 7 trials (...) . Testosterone was also not associated with significant differences in visual memory (-0.28 [95% CI, -0.76 to 0.19]; P = .24), executive function (-5.51 [95% CI, -12.91 to 1.88]; P = .14), or spatial ability (-0.12 [95% CI, -1.89 to 1.65]; P = .89).Among older men with low testosterone and age-associated memory impairment, treatment with testosterone for 1 year compared with placebo was not associated with improved memory or other cognitive functions.clinicaltrials.gov Identifier: NCT00799617.

2017 JAMA Controlled trial quality: predicted high

1026. Effect of Collaborative Care vs Usual Care on Depressive Symptoms in Older Adults With Subthreshold Depression: The CASPER Randomized Clinical Trial. Full Text available with Trip Pro

among 705 participants aged 65 years or older with Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) subthreshold depression; participants were followed up for 12 months.Collaborative care (n=344) was coordinated by a case manager who assessed functional impairments relating to mood symptoms. Participants were offered behavioral activation and completed an average of 6 weekly sessions. The control group received usual primary care (n=361).The primary outcome was self-reported (...) Effect of Collaborative Care vs Usual Care on Depressive Symptoms in Older Adults With Subthreshold Depression: The CASPER Randomized Clinical Trial. There is little evidence to guide management of depressive symptoms in older people.To evaluate whether a collaborative care intervention can reduce depressive symptoms and prevent more severe depression in older people.Randomized clinical trial conducted from May 24, 2011, to November 14, 2014, in 32 primary care centers in the United Kingdom

2017 JAMA Controlled trial quality: predicted high

1027. [Elderly patients and intensive care: Systematic review and geriatrician's point of view]. (Abstract)

on cardiorespiratory arrest, shock, acute respiratory failure and delirium. The mortality rate of patients over 80 years old in intensive care unit can reach up to 70% at 1year, but is dependent on many factors, such as comorbidities or frailty. Above all, more than half of elderly patients recover their long-term autonomy. Their quality of life is comparable to that of the same age population. Considering that the first 3months after an intensive care unit stay are the most decisive in terms of vital (...) [Elderly patients and intensive care: Systematic review and geriatrician's point of view]. The global population is aging and intensive care unit admission rate of elderly patients is dramatically increasing. The objective of this review is to provide an overview of the literature about the management of elderly patients in intensive care unit and more specifically about epidemiology, admission criteria, mortality, functional prognosis and ethical aspects. We also discuss the data

2017 La Revue de medecine interne

1028. Clinical activity and tolerability of FOLFIRI and cetuximab in elderly patients with metastatic colorectal cancer in the CAPRI-GOIM first-line trial Full Text available with Trip Pro

data are available on the efficacy and safety of anti-epidermal growth factor receptor (anti-EGFR) agents on elderly patients with mCRC. In the current study we evaluated the efficacy and safety of FOLFIRI plus cetuximab in age-defined subgroups.A post-hoc analysis was performed in CAPRI trial patients; outcomes (progression-free survival (PFS), overall response rate (ORR), safety) were analysed by age-groups and stratified according to molecular characterisation. 3 age cut-offs were used to define (...) was acceptable in elderly patients. Similar ORR and PFS were observed according to age-groups. No differences in adverse events were reported among the defined subgroups with the exception of higher incidence of grade ≥3 diarrhoea and neutropaenia in patients ≥75 years and grade ≥3 fatigue in patients <75 years.2009-014041-81.

2017 ESMO open

1029. What Ages Hair? Full Text available with Trip Pro

What Ages Hair? 28492040 2018 11 13 2352-6475 3 1 Suppl 2017 Mar International journal of women's dermatology Int J Womens Dermatol What Ages Hair? S52-S57 10.1016/j.ijwd.2017.02.010 Monselise Assaf A Department of Dermatology and Skin Science, University of British Columbia, BC, Canada. Private practice, Tel Aviv, Israel. Cohen David E DE The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, NY, USA. Wanser Rita R Cicatricial Alopecia Research Foundation (...) Dermatol. 2010 Jan;62(1):145-7 20082891 J Am Acad Dermatol. 1999 Nov;41(5 Pt 1):717-21 10534633 Arch Dermatol. 2006 Mar;142(3):298-302 16549704 J Am Acad Dermatol. 2010 Mar;62(3):402-8 20159306 Clin Geriatr Med. 2002 Feb;18(1):121-33, vii 11913736 J Investig Dermatol Symp Proc. 1999 Dec;4(3):282-4 10674382 Clin Dermatol. 1988 Oct-Dec;6(4):108-18 3214816 J Am Acad Dermatol. 2006 Jul;55(1):71-4 16781295 J Cosmet Dermatol. 2007 Mar;6(1):9-13 17348989

2017 International journal of women's dermatology

1030. Surgery for cataracts in people with age-related macular degeneration. Full Text available with Trip Pro

Surgery for cataracts in people with age-related macular degeneration. Cataract and age-related macular degeneration (AMD) are common causes of decreased vision that often occur simultaneously in people over age 50. Although cataract surgery is an effective treatment for cataract-induced visual loss, some clinicians suspect that such an intervention may increase the risk of worsening of underlying AMD and thus have deleterious effects on vision.The objective of this review was to evaluate (...) evidence). However, we could not analyze scores from the Visual Function-14 (VF-14) questionnaire from the other study due to insufficient data. No postoperative complication was reported from either study.At this time, it is not possible to draw reliable conclusions from the available data as to whether cataract surgery is beneficial or harmful in people with AMD after 12 months. Although cataract surgery provides short-term (six months) improvement in BCVA in eyes with AMD compared with no surgery

2017 Cochrane

1031. Fractionated Concurrent Exercise throughout the Day Does Not Promote Acute Blood Pressure Benefits in Hypertensive Middle-aged Women Full Text available with Trip Pro

Fractionated Concurrent Exercise throughout the Day Does Not Promote Acute Blood Pressure Benefits in Hypertensive Middle-aged Women Hypertension is a chronic disease that affects about 30% of the world's population, and the physical exercise plays an important role on its non-pharmacological treatment. Anywise, the dose-response of physical exercise fractionation throughout the day demands more investigation, allowing new exercise prescription possibilities. Therefore, this study aimed (...) to analyze the acute blood pressure (BP) kinetics after 1 h of exercises and the BP reactivity after different concurrent exercise (CE) sessions and its fractioning of hypertensive middle-aged women. In this way, 11 hypertensive women voluntarily underwent three experimental sessions and one control day [control session (CS)]. In the morning session (MS) and night session (NS), the exercise was fully realized in the morning and evening, respectively. For the fractionized session (FS), 50% of the volume

2017 Frontiers in cardiovascular medicine

1032. The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study. Full Text available with Trip Pro

The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study. Total joint replacements for end-stage osteoarthritis of the hip and knee are cost-effective and demonstrate significant clinical improvement. However, robust population based lifetime-risk data for implant revision are not available to aid patient decision making, which is a particular problem in young patient groups deciding on best-timing (...) for surgery.We did implant survival analysis on all patients within the Clinical Practice Research Datalink who had undergone total hip replacement or total knee replacement. These data were adjusted for all-cause mortality with data from the Office for National Statistics and used to generate lifetime risks of revision surgery based on increasing age at the time of primary surgery.We identified 63 158 patients who had undergone total hip replacement and 54 276 who had total knee replacement between Jan 1

2017 Lancet

1033. Cycling provision separated from motor traffic: a systematic review exploring whether stated preferences vary by gender and age. Full Text available with Trip Pro

for cycle infrastructure varied by gender and/or by age. Forty-four of these studies considered the extent of separation from motor traffic. The remainder of the studies covered diverse topics, including preferred winter maintenance methods and attitudes to cycle track lighting. We found that women reported stronger preferences than men for greater separation from motor traffic. There was weaker evidence of stronger preferences among older people. Differences in preferences were quantitative rather than (...) Cycling provision separated from motor traffic: a systematic review exploring whether stated preferences vary by gender and age. In this paper, we represent a systematic review of stated preference studies examining the extent to which cycle infrastructure preferences vary by gender and by age. A search of online, English-language academic and policy literature was followed by a three-stage screening process to identify relevant studies. We found 54 studies that investigated whether preferences

2017 Transport reviews

1034. Mosaic chromosome 20q deletions are more frequent in the aging population Full Text available with Trip Pro

Mosaic chromosome 20q deletions are more frequent in the aging population Deletions on the long-arm of chromosome 20, del(20q), are common karyotypic abnormalities in myeloid disorders. Bioinformatic analyses of the B-allele frequency and log R ratio values from genome-wide association data have identified individuals who are mosaic for large structural abnormalities (>2 Mb). We investigated the most common autosomal event, namely mosaic del(20q), in 46 254 nonhematologic cancer cases and 36 (...)  229 cancer-free controls. We detected 91 mosaic del(20q) in leukocytes (80%) and buccal material (20%). The mosaic del(20q) mapped to a well-characterized minimally deleted region (MDR) reported in myeloid disorders. Common breakpoint clusters map to the coordinates of 29.9 to 31.5 Mb on the centromeric side of mosaic del(20q), and 42.0 to 45.4 Mb and 48.1 to 50.7 Mb on the telomeric end (GRCh36). Multivariate analyses suggest del(20q) increases with age, and is more common in males but less

2017 Blood advances

1035. Meta-analysis comparing total hip arthroplasty with hemiarthroplasty in the treatment of displaced femoral neck fractures in patients over 70 years old. (Abstract)

Meta-analysis comparing total hip arthroplasty with hemiarthroplasty in the treatment of displaced femoral neck fractures in patients over 70 years old. Total hip arthroplasty (THA) and hemiarthroplasty (HA) are effective methods currently used to treat femoral neck fracture in elderly patients, but the two options remain controversial in patients over 70 years old. The main purpose of our study was to determine whether THA or HA is a superior treatment of femoral fractures involving (...) exhibited significantly less pain and better function and were less likely to require a revision hip surgery. Postoperative infection was equally common among HA and THA patients.The significant differences in outcomes suggest that THA is a valuable treatment option for active elderly hip fracture individuals. However, patients who are older, impaired or institutionalized benefit from HA.

2017 Chinese journal of traumatology = Zhonghua chuang shang za zhi

1036. Parental Views of Promoting Fruit and Vegetable Intake Among Overweight Preschoolers and School-Aged Children Full Text available with Trip Pro

Parental Views of Promoting Fruit and Vegetable Intake Among Overweight Preschoolers and School-Aged Children Given the importance of parental influence on children's eating habits, we explored perceptions of parents of overweight (body mass index-for-age percentile ≥85%) preschoolers (3-5 years) and overweight school-aged children (6-12 years) regarding challenges in promoting fruit and vegetable intake and how they and other family members influence their overweight children's dietary habits (...) . Focus groups were conducted with 13 parents of overweight preschoolers and 14 parents of overweight school-aged children. Codes and themes were developed by inductive data analysis. Four common themes were identified: short shelf life of fresh fruits and vegetables prohibiting parents from purchasing, children's taste changes in fruits and vegetables, parents having the primary influence on children's dietary intake, and wanting fruits and vegetables "ready to go." Parents of school-aged children

2017 Global qualitative nursing research

1037. Association between perceived psychological stress and cognitive decline in aging: a systematic review protocol. (Abstract)

Association between perceived psychological stress and cognitive decline in aging: a systematic review protocol. The objective of this review is to identify, appraise and synthesize the best available evidence on the association between perceived psychological stress and cognitive decline in aging.

2017 JBI database of systematic reviews and implementation reports

1038. The effect of complex falls prevention interventions on falls in residential aged care settings: a systematic review protocol. Full Text available with Trip Pro

The effect of complex falls prevention interventions on falls in residential aged care settings: a systematic review protocol. The objective of this review is to synthesize the best available evidence on the effectiveness of complex falls prevention interventions on fall reductions in the residential aged care population, implemented at two or more of the following levels: organization, facility or resident.Specifically the review question is: What is the effect of complex falls prevention (...) interventions on falls in residential aged care settings?

2017 JBI database of systematic reviews and implementation reports

1039. Effectiveness of multi-component interventions on incidence of delirium in hospitalized older patients with hip fracture: a systematic review protocol. (Abstract)

Effectiveness of multi-component interventions on incidence of delirium in hospitalized older patients with hip fracture: a systematic review protocol. The objective of this systematic review is to identify, evaluate and synthesize evidence on the effectiveness of multi-component interventions on the incidence of delirium in hospitalized elderly patients with hip fracture.Specifically, the review question is: In hospitalized older patients with hip fracture, what is the effectiveness of multi

2017 JBI database of systematic reviews and implementation reports

1040. Risk factors for acute care hospital readmission in older persons in Western countries: a systematic review. (Abstract)

Risk factors for acute care hospital readmission in older persons in Western countries: a systematic review. Hospital readmission in older persons is common and reported as a post-discharge adverse outcome from hospitalization. Readmission relates to a mix of factors associated with increasing age, living conditions, progression of disease as well as factors related to the processes of care. To allow health professionals to focus more intensively on patients at risk of readmission (...) , there is a need to identify the characteristics of those patients.To identify and synthesize the best available evidence on risk factors for acute care hospital readmission within one month of discharge in older persons in Western countries.Participants were older persons from Western countries, hospitalized and discharged home or to residential care facilities.The factors of interest considered generic factors related to socio-demographics, health characteristics and clinical and organizational factors

2017 JBI database of systematic reviews and implementation reports