Latest & greatest articles for elderly

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on elderly or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on elderly and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for elderly

981. Daily oral vitamin B-12 with or without folic acid for 24 weeks did not improve cognitive function in elderly people

Daily oral vitamin B-12 with or without folic acid for 24 weeks did not improve cognitive function in elderly people Daily oral vitamin B-12 with or without folic acid for 24 weeks did not improve cognitive function in elderly people | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Daily oral vitamin B-12 with or without folic acid for 24 weeks did not improve cognitive function in elderly people Article Text Therapeutics Daily oral

2008 Evidence-Based Medicine

982. The Growing Burden of Diabetes Mellitus in the US Elderly Population (PubMed)

The Growing Burden of Diabetes Mellitus in the US Elderly Population The prevalence of diabetes mellitus is growing worldwide. Consequently, there has been increased emphasis on primary and secondary prevention of diabetes. To our knowledge, whether there have been actual improvements in outcomes in the last decade or so has not been documented in a nationally representative sample.We undertook this study to examine trends in rates of occurrence of diabetes and its complications in persons

Full Text available with Trip Pro

2008 EvidenceUpdates

983. Prediction of mortality in community-living frail elderly people with long-term care needs. (PubMed)

Prediction of mortality in community-living frail elderly people with long-term care needs. To develop and validate a prognostic index for mortality in community-living, frail elderly people.Cohort study of Program of All-Inclusive Care for the Elderly (PACE) participants enrolled between 1988 and 1996.Eleven PACE sites, a community-based long-term care program that cares for frail, chronically ill elderly people who meet criteria for nursing home placement.Three thousand eight hundred ninety (...) and validation cohorts, respectively.A multidimensional prognostic index was developed and validated using age, sex, functional status, and comorbidities that effectively stratifies frail, community-living elderly people into groups at varying risk of mortality.

2008 EvidenceUpdates

984. Lung cancer in elderly patients: an analysis of the surveillance, epidemiology, and end results database. (PubMed)

Lung cancer in elderly patients: an analysis of the surveillance, epidemiology, and end results database. To study the burden and outcome of lung cancer in the elderly, particularly for patients aged 80 years and older.The national Surveillance, Epidemiology, and End Results database was analyzed for lung cancer outcomes during the period 1988 to 2003. A comparison was carried out between patients with lung cancer 80 years and older, 70 to 79 years, and younger than 70 years for demographics (...) ; stage distribution; 5-year relative survival; and survival based on histology, sex, race, stage, and treatment. The temporal trends in survival during the years 1988 to 1997 and 1998 to 2003 were also analyzed.Of 316,682 patients eligible for the analysis, 45,912 (14%) were 80 years or older (ie, very elderly); 103,963 (33%) were 70 to 79 years; and 166,807 (53%) were younger than 70 years. The distribution by stage and histology was comparable for all the three groups. Overall survival rate at 5

2008 EvidenceUpdates

985. Amantadine and rimantadine for influenza A in children and the elderly. (PubMed)

Amantadine and rimantadine for influenza A in children and the elderly. Although amantadine (AMT) and rimantadine (RMT) are used to relieve or treat influenza A symptoms in healthy adults, little is known about the effectiveness and safety of these antivirals in preventing and treating influenza A in children and the elderly.The aim of this review was to systematically consider evidence on the effectiveness and safety of AMT and RMT in preventing and treating influenza A in children (...) and the elderly.We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, 2007, issue 3); MEDLINE (1966 to July 2007) and EMBASE (1980 to July 2007).Randomised or quasi-randomised trials comparing AMT and/or RMT in children and the elderly with placebo, control, other antivirals or comparing different doses or schedules of AMT and/or RMT or no intervention.Two review authors independently selected trials for inclusion and assessed methodological quality. Disagreements were

Full Text available with Trip Pro

2008 Cochrane

986. Effect of community-based intervention using depression screening on elderly suicide risk: a meta-analysis of the evidence from Japan

Effect of community-based intervention using depression screening on elderly suicide risk: a meta-analysis of the evidence from Japan Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2008 DARE.

987. Interventions to prevent disability in frail community-dwelling elderly: a systematic review

Interventions to prevent disability in frail community-dwelling elderly: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2008 DARE.

988. Screening tools to identify hospitalised elderly patients at risk of functional decline: a systematic review

Screening tools to identify hospitalised elderly patients at risk of functional decline: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2008 DARE.

989. Complex interventions to improve physical function and maintain independent living in elderly people: a systematic review and meta-analysis

Complex interventions to improve physical function and maintain independent living in elderly people: a systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2008 DARE.

990. Cost-utility of a walking programme for moderately depressed, obese, or overweight elderly women in primary care: a randomised controlled trial

Cost-utility of a walking programme for moderately depressed, obese, or overweight elderly women in primary care: a randomised controlled trial Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2008 NHS Economic Evaluation Database.

991. Low dose aspirin and cognitive function in middle aged to elderly adults: randomised controlled trial. (PubMed)

Low dose aspirin and cognitive function in middle aged to elderly adults: randomised controlled trial. To determine the effects of low dose aspirin on cognitive function in middle aged to elderly men and women at moderately increased cardiovascular risk.Randomised double blind placebo controlled trial.Central Scotland.3350 men and women aged over 50 participating in the aspirin for asymptomatic atherosclerosis trial.Low dose aspirin (100 mg daily) or placebo for five years.Tests of memory (...) general factor cognitive score (32.7% and 34.8% respectively, odds ratio 0.91, 95% confidence interval 0.79 to 1.05, P=0.20) or in mean scores on the individual cognitive tests. There were also no significant differences in change in cognitive ability over the five years in a subset of 504 who underwent detailed cognitive testing at baseline.Low dose aspirin does not affect cognitive function in middle aged to elderly people at increased cardiovascular risk.ISRCTN 66587262.

Full Text available with Trip Pro

2008 BMJ Controlled trial quality: predicted high

992. Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial. (PubMed)

Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial. Cognitive decline, mood, behavioral and sleep disturbances, and limitations of activities of daily living commonly burden elderly patients with dementia and their caregivers. Circadian rhythm disturbances have been associated with these symptoms.To determine whether the progression of cognitive and noncognitive symptoms may be ameliorated (...) , both for positive affect (-0.5 points; 95% CI, -0.10 to -1.00) and negative affect (0.8 points; 95% CI, 0.20-1.44). Melatonin also increased withdrawn behavior by 1.02 points (95% CI, 0.18-1.86) on the Multi Observational Scale for Elderly Subjects scale, although this effect was not seen if given in combination with light. Combined treatment also attenuated aggressive behavior by 3.9 points (95% CI, 0.88-6.92) on the Cohen-Mansfield Agitation Index or 9%, increased sleep efficiency by 3.5% (95% CI

Full Text available with Trip Pro

2008 JAMA Controlled trial quality: predicted high

993. Effectiveness of multifaceted fall-prevention programs for the elderly in residential care

Effectiveness of multifaceted fall-prevention programs for the elderly in residential care Effectiveness of multifaceted fall-prevention programs for the elderly in residential care Effectiveness of multifaceted fall-prevention programs for the elderly in residential care Cusimano MD, Kwok J, Spadafora K CRD summary This review found limited evidence that multifaceted intervention programmes can prevent falls in elderly residents in residential care. The authors' conclusions were appropriate (...) . Implications of the review for practice and research Practice : The authors stated that multifaceted prevention programs (including environmental modification, education on falls prevention, medication reviews and the provision of hip protectors) may be best targeted to high-risk groups of elderly residents, such as recurrent fallers. Research : The authors stated that there was insufficient evidence on adverse outcomes, costs, cost-effectiveness and sustainability of programmes. Future studies should

Full Text available with Trip Pro

2008 DARE.

994. Treatment of elderly hypertensive patients with epithelial sodium channel inhibitors combined with a thiazide diuretic reduces coronary mortality and sudden cardiac death

Treatment of elderly hypertensive patients with epithelial sodium channel inhibitors combined with a thiazide diuretic reduces coronary mortality and sudden cardiac death Treatment of elderly hypertensive patients with epithelial sodium channel inhibitors combined with a thiazide diuretic reduces coronary mortality and sudden cardiac death Treatment of elderly hypertensive patients with epithelial sodium channel inhibitors combined with a thiazide diuretic reduces coronary mortality and sudden (...) cardiac death Hebert PR, Coffey CS, Byrne DW, Scott TA, Fagard RH, Rottman JN, Murray KT, Oates JA CRD summary The authors concluded that use of an epithelial sodium channel inhibitor combined with hydrochlorothiazide for treatment of hypertension in elderly patients resulted in favourable effects on coronary mortality or sudden cardiac death. The reliability of the conclusions is uncertain given a number of weaknesses in the review methods (risk of error and bias, unclear quality of included studies

Full Text available with Trip Pro

2008 DARE.

995. Screening for alcohol misuse in elderly primary care patients: a systematic literature review

Screening for alcohol misuse in elderly primary care patients: a systematic literature review Screening for alcohol misuse in elderly primary care patients: a systematic literature review Screening for alcohol misuse in elderly primary care patients: a systematic literature review Berks J, McCormick R CRD summary The authors concluded that the Alcohol Use Disorders Identification Test (AUDIT) was a useful screen for detecting harmful and hazardous drinking in the elderly and that the CAGE test (...) was valuable when screening for dependence. The authors' conclusions reflected the evidence presented, however, due to poor reporting of review processes the reliability of the conclusions is unclear. Authors' objectives To evaluate paper-and-pen screening tools for alcohol misuse in elderly primary care patients. Searching The electronic databases MEDLINE and PsycINFO were searched to identify relevant articles written in English. Search terms were reported. The reference lists from relevant publications

2008 DARE.

996. Cost benefit considerations of preventing elderly falls through environmental modifications to homes in Hana, Maui

Cost benefit considerations of preventing elderly falls through environmental modifications to homes in Hana, Maui Cost benefit considerations of preventing elderly falls through environmental modifications to homes in Hana, Maui Cost benefit considerations of preventing elderly falls through environmental modifications to homes in Hana, Maui Ling C, Henderson S, Henderson R, Henderson M, Pedro T, Pang L Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The objective was to examine the clinical and economic impact of a programme of home environment improvements to prevent falls in the elderly. The authors concluded that the implementation of the home modifications programme reduced both the rate of falls and the fall-related medical

2008 NHS Economic Evaluation Database.

997. Cost-effectiveness of a multidisciplinary fall prevention program in community-dwelling elderly people: a randomized controlled trial (ISRCTN 64716113)

Cost-effectiveness of a multidisciplinary fall prevention program in community-dwelling elderly people: a randomized controlled trial (ISRCTN 64716113) Cost-effectiveness of a multidisciplinary fall prevention program in community-dwelling elderly people: a randomized controlled trial (ISRCTN 64716113) Cost-effectiveness of a multidisciplinary fall prevention program in community-dwelling elderly people: a randomized controlled trial (ISRCTN 64716113) Hendriks M R, Evers S M, Bleijlevens M H (...) -dwelling elderly. The study demonstrated that the multidisciplinary intervention programme was not cost-effective compared with usual care in the Dutch setting, as the two strategies were similarly costly and effective. The study methodology was of satisfactory quality and was presented clearly, so the authors’ conclusions appear valid. Type of economic evaluation Cost-effectiveness analysis, cost-utility analysis Study objective The objective was to examine the cost-effectiveness

2008 NHS Economic Evaluation Database.

998. Non-pharmaceutical prevention of hip fractures: a cost-effectiveness analysis of a community-based elderly safety promotion program in Sweden

Non-pharmaceutical prevention of hip fractures: a cost-effectiveness analysis of a community-based elderly safety promotion program in Sweden Non-pharmaceutical prevention of hip fractures: a cost-effectiveness analysis of a community-based elderly safety promotion program in Sweden Non-pharmaceutical prevention of hip fractures: a cost-effectiveness analysis of a community-based elderly safety promotion program in Sweden Johansson P, Sadigh S, Tillgren P, Rehnberg C Record Status (...) was 6.45 million SEK and the costs avoided were 6.52 million SEK, so the programme was cost-saving overall. The proposed programme was the dominant strategy because it was both less expensive and more effective than no programme. The cost-effectiveness ratio was most sensitive to the assumption of no costs and health effects after the first year following hip fracture and the lowest effectiveness estimate for the programme. Authors' conclusions The authors concluded that the community-based elderly

Full Text available with Trip Pro

2008 NHS Economic Evaluation Database.

999. Cost-effectiveness of preventing hip fractures by hip protectors in elderly institutionalized residents in Germany

Cost-effectiveness of preventing hip fractures by hip protectors in elderly institutionalized residents in Germany Cost-effectiveness of preventing hip fractures by hip protectors in elderly institutionalized residents in Germany Cost-effectiveness of preventing hip fractures by hip protectors in elderly institutionalized residents in Germany Gandjour A, Weyler EJ Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract (...) contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study examined the cost-effectiveness of hip protectors for an institutionalised elderly population, in Germany. The authors concluded that hip protectors were a cost-effective strategy compared with no prevention. On the whole, the methodology was valid and the authors’ conclusions appear to be appropriate. Type

Full Text available with Trip Pro

2008 NHS Economic Evaluation Database.

1000. Treatment of elevated blood pressure in the very elderly: Less is better

Treatment of elevated blood pressure in the very elderly: Less is better [71] Treatment of elevated blood pressure in the very elderly: Less is better | Therapeutics Initiative Independent Healthcare Evidence > > [71] Treatment of elevated blood pressure in the very elderly: Less is better Risk of serious adverse cardiovascular events increases with advancing age and with higher blood pressure. Falls and other serious adverse events associated with postural hypotension also increase with age (...) (95%CI 0.95, 1.25). The authors concluded that, because of the potential for an increase in mortality due to treatment, further trials were necessary. What have we learned from the two HYVET studies? The HYpertension in the Very Elderly Trial (HYVET) investigators designed two trials to determine whether antihypertensive treatment was beneficial in this older age group. The HYVET investigators began with a pilot open label multicentre RCT3 published in 2003. It was conducted in 10 European

2008 Therapeutics Letter