Latest & greatest articles for elderly

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Top results for elderly

941. Current use of SSRIs and tricyclic antidepressants may increase the risk of non-vertebral fractures in the elderly

Current use of SSRIs and tricyclic antidepressants may increase the risk of non-vertebral fractures in the elderly Current use of SSRIs and tricyclic antidepressants may increase the risk of non-vertebral fractures in the elderly | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Current use of SSRIs and tricyclic antidepressants may increase the risk of non-vertebral fractures in the elderly Article Text Aetiology Current use of SSRIs

2009 Evidence-Based Mental Health

942. A stepped care intervention is effective for elderly people with subthreshold depression or anxiety

A stepped care intervention is effective for elderly people with subthreshold depression or anxiety A stepped care intervention is effective for elderly people with subthreshold depression or anxiety | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here A stepped care intervention is effective for elderly people with subthreshold depression or anxiety Article Text Therapeutics A stepped care intervention is effective for elderly people

2009 Evidence-Based Mental Health

943. A stepped-care prevention programme decreased depression and anxiety disorders in elderly patients

A stepped-care prevention programme decreased depression and anxiety disorders in elderly patients A stepped-care prevention programme decreased depression and anxiety disorders in elderly patients | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here A stepped-care prevention programme decreased depression and anxiety disorders in elderly patients Article Text Therapeutics A stepped-care prevention programme decreased depression

2009 Evidence-Based Medicine

944. Review: exercise interventions reduce falls in elderly people living in the community

Review: exercise interventions reduce falls in elderly people living in the community Review: exercise interventions reduce falls in elderly people living in the community | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers (...) of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: exercise interventions reduce falls in elderly people living in the community Article Text Therapeutics Review: exercise interventions reduce falls in elderly people living in the community Statistics from

2009 Evidence-Based Medicine

945. BNP-guided vs symptom-guided heart failure therapy: the Trial of Intensified vs Standard Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF) randomized trial. Full Text available with Trip Pro

BNP-guided vs symptom-guided heart failure therapy: the Trial of Intensified vs Standard Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF) randomized trial. It is uncertain whether intensified heart failure therapy guided by N-terminal brain natriuretic peptide (BNP) is superior to symptom-guided therapy.To compare 18-month outcomes of N-terminal BNP-guided vs symptom-guided heart failure therapy.Randomized controlled multicenter Trial of Intensified vs Standard (...) Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF) of 499 patients aged 60 years or older with systolic heart failure (ejection fraction < or = 45%), New York Heart Association (NYHA) class of II or greater, prior hospitalization for heart failure within 1 year, and N-terminal BNP level of 2 or more times the upper limit of normal. The study had an 18-month follow-up and it was conducted at 15 outpatient centers in Switzerland and Germany between January 2003 and June 2008

2009 JAMA Controlled trial quality: predicted high

946. A Systematic Review of the Preventive Effect of Oral Hygiene on Pneumonia and Respiratory Tract Infection in Elderly People in Hospitals and Nursing Homes (Abstract)

A Systematic Review of the Preventive Effect of Oral Hygiene on Pneumonia and Respiratory Tract Infection in Elderly People in Hospitals and Nursing Homes The objective of this study was to investigate the preventive effect of oral hygiene on pneumonia and respiratory tract infection, focusing on elderly people in hospitals and nursing homes, by systematically reviewing effect estimates and methodological quality of randomized controlled trials (RCTs) and to provide an overview of additional (...) . There was a wide variation in the design and quality of the studies included. The RCTs revealed positive preventive effects of oral hygiene on pneumonia and respiratory tract infection in hospitalized elderly people and elderly nursing home residents, with ARRs from 6.6% to 11.7% and NNTs from 8.6 to 15.3 individuals. The non-RCT studies contributed to inconclusive evidence on the association and correlation between oral hygiene and pneumonia or respiratory tract infection in elderly people. Mechanical oral

2008 EvidenceUpdates

947. Comparison of the Safety and Immunogenicity of 2 Respiratory Syncytial Virus (RSV) Vaccines- Nonadjuvanted Vaccine or Vaccine Adjuvanted with Alum-Given Concomitantly with Influenza Vaccine to High-Risk Elderly Individuals Full Text available with Trip Pro

Comparison of the Safety and Immunogenicity of 2 Respiratory Syncytial Virus (RSV) Vaccines- Nonadjuvanted Vaccine or Vaccine Adjuvanted with Alum-Given Concomitantly with Influenza Vaccine to High-Risk Elderly Individuals Respiratory syncytial virus (RSV) has been recognized recently as an important adult pathogen.This randomized, double-blind, placebo-controlled study was designed to compare humoral responses to licensed trivalent influenza vaccine given concomitantly with 1 of 2 RSV vaccine

2008 EvidenceUpdates Controlled trial quality: uncertain

948. Effect of current and midlife obesity status on mortality risk in the elderly Full Text available with Trip Pro

Effect of current and midlife obesity status on mortality risk in the elderly The primary purpose of this study was to determine whether current and midlife obesity status provide independent information on mortality risk in elderly persons. Analyses were based on 3,238 participants from the original Framingham Heart Study (FHS) cohort who lived to at least 70 years of age and who had BMI measures from when they were in their 50s. Within this group of 70-year olds, obesity based on current BMI (...) , and not significantly different (P > 0.9) in those who were nonobese at 50 years of age and obese at 70 years of age. In summary, in this cohort of elderly adults, midlife and current BMI had independent effects on mortality risk. Specifically, although mortality risk was increased in obese older adults who were already obese at midlife, this was not the case for newly obese older adults. Conversely, nonobese older adults who were obese at midlife had an increased mortality risk. These observations imply

2008 EvidenceUpdates

949. Orthostatic Hypotension and Risk of Cardiovascular Disease in Elderly People: The Rotterdam Study Full Text available with Trip Pro

Orthostatic Hypotension and Risk of Cardiovascular Disease in Elderly People: The Rotterdam Study To determine the prognostic role of orthostatic hypotension for cardiovascular disease (CVD) and all-cause mortality in elderly people.Prospective study.Community based.Five thousand sixty-four subjects from the Rotterdam study aged 55 and older.Orthostatic hypotension was measured using a Dinamap automatic blood pressure recorder. Orthostatic hypotension is defined as a decline in systolic blood (...) interval (CI)=1.08-1.57) and all-cause mortality (HR=1.22, 95% CI=1.09-1.36), in models adjusted for age and sex. The risk was slightly lower after additional adjustment for cardiovascular risk factors. In analyses stratified for age, the HRs for all-cause mortality were 1.80 (95% CI 1.25-2.60), 1.13 (0.89-1.42), and 1.27 (95% CI=1.11-1.44), in the first, second, and third tertile of age, respectively.Orthostatic hypotension increases the risk of CHD and all-cause mortality in elderly people. The risk

2008 EvidenceUpdates

950. Comparison of Cardiovascular Outcomes in Elderly Patients With Diabetes Who Initiated Rosiglitazone vs Pioglitazone Therapy Full Text available with Trip Pro

Comparison of Cardiovascular Outcomes in Elderly Patients With Diabetes Who Initiated Rosiglitazone vs Pioglitazone Therapy Recent meta-analyses have raised the possibility that rosiglitazone maleate may increase the risk of ischemic cardiovascular events, whereas pioglitazone hydrochloride could not be linked to such a risk. We compared cardiovascular outcomes and mortality between patients initiating pioglitazone vs rosiglitazone therapy.We assembled an inception cohort of Medicare

2008 EvidenceUpdates

951. Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people. (Abstract)

Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people. Folate deficiency can result in congenital neural tube defects and megaloblastic anaemia. Low folate levels may be due to insufficient dietary intake or inefficient absorption, but impaired metabolic utilization also occurs.Because B12 deficiency can produce a similar anaemia to folate deficiency, there is a risk that folate supplementation can delay the diagnosis of B12 deficiency (...) benefit from folic acid which was given in combination with B12 needs to be "corrected" for any effect of vitamin B12 alone. A separate Cochrane review of vitamin B12 and cognitive function has therefore been published.To examine the effects of folic acid supplementation, with or without vitamin B12, on elderly healthy or demented people, in preventing cognitive impairment or retarding its progress.Trials were identified from a search of the Cochrane Dementia and Cognitive Improvement Group's

2008 Cochrane

952. Potential Causes of Higher Mortality in Elderly Users of Conventional and Atypical Antipsychotic Medications (Abstract)

Potential Causes of Higher Mortality in Elderly Users of Conventional and Atypical Antipsychotic Medications To investigate the potential mechanisms through which conventional antipsychotic medication (APM) might act, the specific causes of death in elderly patients newly started on conventional APM were compared with those of patients taking atypical APM.Cohort study.Community.All British Columbia residents aged 65 and older who initiated a conventional or atypical APM between 1996 and 2004

2008 EvidenceUpdates

953. Lack of Effectiveness of a Multidisciplinary Fall-Prevention Program in Elderly People at Risk: A Randomized, Controlled Trial (Abstract)

Lack of Effectiveness of a Multidisciplinary Fall-Prevention Program in Elderly People at Risk: A Randomized, Controlled Trial To assess whether a pragmatic multidisciplinary fall-prevention program was more effective than usual care in preventing new falls and functional decline in elderly people.A two-group, randomized, controlled trial with 12 months of follow-up.University hospital and home-based intervention, the Netherlands.Three hundred thirty-three community-dwelling Dutch people aged

2008 EvidenceUpdates Controlled trial quality: uncertain

954. Recovery of kidney function after acute kidney injury in the elderly: a systematic review and meta-analysis (Abstract)

Recovery of kidney function after acute kidney injury in the elderly: a systematic review and meta-analysis The prevalence of elderly individuals continues to increase over time, as does the incidence of acute kidney injury (AKI). However, it is not known whether age is an important prognostic predictor for renal recovery after an episode of AKI.Systematic review of MEDLINE and EMBASE databases and meta-analysis of pooled data using random-effect models.Adults with AKI, not including kidney (...) of kidney function defined as independence from dialysis therapy, decrease in serum creatinine level to less than a defined threshold, or return to baseline kidney function.We obtained data for recovery of kidney function by age from 17 studies of patients with AKI. Overall, 31.3% of surviving elderly patients did not recover kidney function compared with 26% of younger patients (pooled relative risk, 1.28, 95% confidence interval, 1.06 to 1.55; P < 0.05). The increased risk of nonrecovery

2008 EvidenceUpdates

955. Endometrial effects of tibolone in elderly, osteoporotic women Full Text available with Trip Pro

Endometrial effects of tibolone in elderly, osteoporotic women To investigate endometrial effects of tibolone administered to postmenopausal women for 3 years.Postmenopausal women (N=3,519) aged 60-85 years (mean 68 years) with a uterus and with osteoporosis were randomly assigned to receive tibolone orally, 1.25 mg per day, or identical placebo. We evaluated effects on endometrial thickness in all women, and examined endometrial histology in 635 participants considered to be at increased risk

2008 EvidenceUpdates Controlled trial quality: uncertain

956. Review: evidence from single studies shows that very few fall risk assessment tools can predict falls in elderly people

Review: evidence from single studies shows that very few fall risk assessment tools can predict falls in elderly people Review: evidence from single studies shows that very few fall risk assessment tools can predict falls in elderly people | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: evidence from single studies shows that very few fall risk assessment tools can predict falls in elderly people Article Text Clinical prediction

2008 Evidence-Based Nursing

957. Incidental Meniscal Findings on Knee MRI in Middle-Aged and Elderly Persons. Full Text available with Trip Pro

Incidental Meniscal Findings on Knee MRI in Middle-Aged and Elderly Persons. Magnetic resonance imaging (MRI) of the knee is often performed in patients who have knee symptoms of unclear cause. When meniscal tears are found, it is commonly assumed that the symptoms are attributable to them. However, there is a paucity of data regarding the prevalence of meniscal damage in the general population and the association of meniscal tears with knee symptoms and with radiographic evidence

2008 NEJM

958. Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial Full Text available with Trip Pro

Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial Observational epidemiological studies have shown a positive association between hypertension and risk of incident dementia; however, the effects of antihypertensive therapy on cognitive function in controlled trials have been conflicting, and meta-analyses of the trials have not provided clear evidence of whether (...) antihypertensive treatment reduces dementia incidence. The Hypertension in the Very Elderly trial (HYVET) was designed to assess the risks and benefits of treatment of hypertension in elderly patients and included an assessment of cognitive function.Patients with hypertension (systolic pressure 160-200 mm Hg; diastolic pressure <110 mm Hg) who were aged 80 years or older were enrolled in this double-blind, placebo-controlled trial. Participants were randomly assigned to receive 1.5 mg slow release indapamide

2008 EvidenceUpdates Controlled trial quality: predicted high

959. Intradermal Influenza Vaccine Administered Using a New Microinjection System Produces Superior Immunogenicity in Elderly Adults: A Randomized Controlled Trial Full Text available with Trip Pro

Intradermal Influenza Vaccine Administered Using a New Microinjection System Produces Superior Immunogenicity in Elderly Adults: A Randomized Controlled Trial Enhanced influenza vaccines are needed to provide improved protection for elderly individuals. The intradermal vaccination route was hypothesized to provide immunogenicity superior to that provided by the intramuscular vaccination route.In a multicenter, randomized study, 1107 volunteers >60 years of age received intradermal trivalent

2008 EvidenceUpdates Controlled trial quality: uncertain

960. Influenza vaccination and risk of community-acquired pneumonia in immunocompetent elderly people: a population-based, nested case-control study. (Abstract)

Influenza vaccination and risk of community-acquired pneumonia in immunocompetent elderly people: a population-based, nested case-control study. Pneumonia is a common complication of influenza infection in elderly individuals and could therefore potentially be prevented by influenza vaccination. In studies with data from administrative sources, vaccinated elderly people had a reduced risk of admission for pneumonia compared with unvaccinated seniors; however, these findings could have been (...) biased by underlying differences in health between the groups. Furthermore, since most individuals with pneumonia are not treated in hospital, such studies should include both outpatient and inpatient events. We therefore assessed whether influenza vaccination is associated with a reduced risk of community-acquired pneumonia in immunocompetent elderly people after controlling for health status indicators.We did a population-based, nested case-control study in immunocompetent elderly people aged 65-94

2008 Lancet