Latest & greatest articles for elderly

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Top results for elderly

781. How income and food prices influence global dietary intakes by age and sex: evidence from 164 countries Full Text available with Trip Pro

How income and food prices influence global dietary intakes by age and sex: evidence from 164 countries While income and prices are key drivers of dietary choices, how their influence varies by food category, nation, and demographics is not well established. Based on intake data for 164 countries and 11 food categories, we examined how income and food prices relate to food intake globally, including by world region, age, and sex.We used 2010 intake data from the Global Dietary Database (...) , the first database of consumption estimates for major food categories by country, age, and sex. We combined these data with national per capita GDP and food price data. We estimated intake responsiveness to income and prices for each food category, accounting for differences by national income, world region, age, and sex.We identified several differences in intake responsiveness. For example, rising income was estimated to increase milk intake most strongly in Sub-Saharan Africa and fruit intake most

2017 BMJ global health

782. Facilitators and barriers to modern contraception use among reproductive-aged women living in sub-Saharan Africa: a qualitative systematic review protocol. (Abstract)

Facilitators and barriers to modern contraception use among reproductive-aged women living in sub-Saharan Africa: a qualitative systematic review protocol. The main objective of this qualitative review is to synthesize the best available evidence on facilitators and barriers of modern contraception use among reproductive-aged (15-49 years) women living in sub-Saharan Africa [SSA].The specific review questions are.

2017 JBI database of systematic reviews and implementation reports

783. Comprehensive geriatric assessment for older adults admitted to hospital. Full Text available with Trip Pro

Comprehensive geriatric assessment for older adults admitted to hospital. Comprehensive geriatric assessment (CGA) is a multi-dimensional, multi-disciplinary diagnostic and therapeutic process conducted to determine the medical, mental, and functional problems of older people with frailty so that a co-ordinated and integrated plan for treatment and follow-up can be developed. This is an update of a previously published Cochrane review.We sought to critically appraise and summarise current (...) evidence on the effectiveness and resource use of CGA for older adults admitted to hospital, and to use these data to estimate its cost-effectiveness.We searched CENTRAL, MEDLINE, Embase, three other databases, and two trials registers on 5 October 2016; we also checked reference lists and contacted study authors.We included randomised trials that compared inpatient CGA (delivered on geriatric wards or by mobile teams) versus usual care on a general medical ward or on a ward for older people, usually

2017 Cochrane

784. Patterns of Sedentary Behavior and Mortality in U.S. Middle-Aged and Older Adults: A National Cohort Study. Full Text available with Trip Pro

Patterns of Sedentary Behavior and Mortality in U.S. Middle-Aged and Older Adults: A National Cohort Study. Excessive sedentary time is ubiquitous in Western societies. Previous studies have relied on self-reporting to evaluate the total volume of sedentary time as a prognostic risk factor for mortality and have not examined whether the manner in which sedentary time is accrued (in short or long bouts) carries prognostic relevance.To examine the association between objectively measured (...) sedentary behavior (its total volume and accrual in prolonged, uninterrupted bouts) and all-cause mortality.Prospective cohort study.Contiguous United States.7985 black and white adults aged 45 years or older.Sedentary time was measured using a hip-mounted accelerometer. Prolonged, uninterrupted sedentariness was expressed as mean sedentary bout length. Hazard ratios (HRs) were calculated comparing quartiles 2 through 4 to quartile 1 for each exposure (quartile cut points: 689.7, 746.5, and 799.4 min/d

2017 Annals of Internal Medicine

785. Hemocoagulase might not control but worsen gastrointestinal bleeding in an elderly patient with type II respiratory failure Full Text available with Trip Pro

Hemocoagulase might not control but worsen gastrointestinal bleeding in an elderly patient with type II respiratory failure Hemocoagulase has been successfully used for the management of bleeding in patients undergoing surgery. Local spray of hemocoagulase during endoscopic therapy may be effective for the management of gastrointestinal bleeding. In China, intravenous infusion of hemocoagulase is given by some physicians for the treatment of gastrointestinal bleeding. However, the potential (...) adverse events secondary to hemocoagulase, such as hypofibrinogenemia, are poorly recognized. In this paper, we reported an elderly patient with type II respiratory failure in whom hemocoagulase might induce hypofibrinogenemia and further worsen gastrointestinal bleeding. We highlighted that fibrinogen levels should be cautiously monitored in patients receiving hemocoagulase.

2017 Translational gastroenterology and hepatology

786. The conceptualization of a Just-In-Time Adaptive Intervention (JITAI) for the reduction of sedentary behavior in older adults Full Text available with Trip Pro

appropriate support in real-life. In this paper we integrated behavior change and aging theory and research as well as knowledge around older adult's technology use to conceptualize a JITAI targeting the reduction of sedentary behavior in older adults. The JITAIs ultimate goal is to encourage older adults to take regular activity breaks from prolonged sitting. As a proximal outcome, we suggest the number of daily activity breaks from sitting. Support provided to interrupt sitting time can be based (...) The conceptualization of a Just-In-Time Adaptive Intervention (JITAI) for the reduction of sedentary behavior in older adults Low physical activity and high sedentary behavior in older adults can be addressed with interventions that are delivered through modern technology. Just-In-Time Adaptive Interventions (JITAIs) are an emerging technology-driven behavior-change intervention type and capitalize on data that is collected via mobile sensing technology (e.g., smartphones) to trigger

2017 mHealth

787. Blockage of regulatory T cells augments induction of protective immune responses by influenza virus-like particles in aged mice Full Text available with Trip Pro

Blockage of regulatory T cells augments induction of protective immune responses by influenza virus-like particles in aged mice Elderly humans over 65 years old are at great risk to pathogenesis by influenza virus infection. However, although influenza vaccines provide effective protection in healthy young adults, protection of elderly adults is substantially lower even with a good match between the vaccine and the circulating influenza virus. To gain insight of the underlying mechanism (...) for the reduced immunogenicity of influenza vaccines in the aged population, we investigated immunogenicity of influenza virus-like particle vaccines in aged mice, which represent a useful model for studying aging associated impairment in immune responses. Specifically, we investigated the effect of inhibiting regulatory T cells in aged mice on induction of protective immune responses by influenza vaccines. Our results showed that injecting anti-CD25 antibodies could down-regulate CD25 on the surface

2017 Microbes and infection

788. Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex Full Text available with Trip Pro

Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex The incidence and mortality rates of B-cell acute lymphoblastic leukemia (B-ALL) differ by age and sex. To determine if inherited genetic susceptibility contributes to these differences we performed 2 genome-wide association studies (GWAS) by age, sex, and subtype and subsequent meta-analyses. The GWAS included 446 B-ALL cases, and 3027 healthy unrelated blood and marrow (...) . A previously identified adolescent and young-adult onset ALL-associated variant in GATA3 is associated with B-ALL risk in those >40 years. Our findings provide more evidence of the influence of genetics on B-ALL age of onset and we have shown the first evidence that IKZF1 associations with B-ALL may be sex and age specific.

2017 Blood advances

789. Chronic Effects of Different Rest Intervals Between Sets on Dynamic and Isometric Muscle Strength and Muscle Activity in Trained Older Women. (Abstract)

Chronic Effects of Different Rest Intervals Between Sets on Dynamic and Isometric Muscle Strength and Muscle Activity in Trained Older Women. This study investigated the chronic effects of different rest intervals (RIs) between sets on dynamic and isometric muscle strength and muscle activity.We used a repeated-measures design (pretraining and posttraining) with independent groups (different RI). Twenty-one resistance-trained older women (66.4 ± 4.4 years) were randomly assigned to either a 1 (...) and posttraining.There was a significant increase in load of 15 maximum repetitions posttraining for G-3 min only (3.6%; P < 0.05). However, posttraining results showed no significant differences between G-1 min and G-3 min groups for all dependent variables (P > 0.05).The findings suggest that different RIs between sets did not influence dynamic and isometric muscle strength and muscle activity in resistance-trained older women.

2017 American journal of physical medicine & rehabilitation Controlled trial quality: uncertain

790. Vision Screening in Children Aged 6 Months to 5 Years: US Preventive Services Task Force Recommendation Statement. (Abstract)

Vision Screening in Children Aged 6 Months to 5 Years: US Preventive Services Task Force Recommendation Statement. One of the most important causes of vision abnormalities in children is amblyopia (also known as "lazy eye"). Amblyopia is an alteration in the visual neural pathway in a child's developing brain that can lead to permanent vision loss in the affected eye. Among children younger than 6 years, 1% to 6% have amblyopia or its risk factors (strabismus, anisometropia, or both). Early (...) acuity in children aged 3 to 5 years, which are likely to result in permanent improvements in vision throughout life. The USPSTF concluded that the benefits are moderate because untreated amblyopia results in permanent, uncorrectable vision loss, and the benefits of screening and treatment potentially can be experienced over a child's lifetime. The USPSTF found adequate evidence to bound the potential harms of treatment (ie, higher false-positive rates in low-prevalence populations) as small

2017 JAMA

791. Vision Screening in Children Aged 6 Months to 5 Years: Evidence Report and Systematic Review for the US Preventive Services Task Force. (Abstract)

Vision Screening in Children Aged 6 Months to 5 Years: Evidence Report and Systematic Review for the US Preventive Services Task Force. Preschool vision screening could allow detection and treatment of vision abnormalities during a critical developmental stage, preserving function and quality of life.To review the evidence on screening for and treatment of amblyopia, its risk factors, and refractive error in children aged 6 months to 5 years to inform the US Preventive Services Task

2017 JAMA

792. Final efficacy, immunogenicity, and safety analyses of a nine-valent human papillomavirus vaccine in women aged 16-26 years: a randomised, double-blind trial. Full Text available with Trip Pro

(qHPV; HPV 6, 11, 16, and 18) vaccine. We aimed to report efficacy of the 9vHPV vaccine for up to 6 years following first administration and antibody responses over 5 years.We undertook this randomised, double-blind, efficacy, immunogenicity, and safety study of the 9vHPV vaccine study at 105 study sites in 18 countries. Women aged 16-26 years old who were healthy, with no history of abnormal cervical cytology, no previous abnormal cervical biopsy results, and no more than four lifetime sexual (...) Final efficacy, immunogenicity, and safety analyses of a nine-valent human papillomavirus vaccine in women aged 16-26 years: a randomised, double-blind trial. Primary analyses of a study in young women aged 16-26 years showed efficacy of the nine-valent human papillomavirus (9vHPV; HPV 6, 11, 16, 18, 31, 33, 45, 52, and 58) vaccine against infections and disease related to HPV 31, 33, 45, 52, and 58, and non-inferior HPV 6, 11, 16, and 18 antibody responses when compared with quadrivalent HPV

2017 Lancet Controlled trial quality: predicted high

793. Intergenerational Programs? Effect on the Mental Health of the Elderly

, and CINAHL. Keywords included: intergenerational relations, aged or elderly, and mental health. The quality of evidence was assessed using GRADE. Results: Two observational qualitative studies remained after duplicates were eliminated and eligibility criteria were applied. Both studies evaluated elderly exposed to intergenerational programs watching for trends as exposure rates increased. One study showed a decrease in depressive symptoms in a depressed subgroup of older adults and an increase in self (...) Intergenerational Programs? Effect on the Mental Health of the Elderly "Intergenerational Programs’ Effect on the Mental Health of the Elderly" by Alysia Hagert < > > > > > Title Author Date of Graduation Summer 8-12-2017 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies Rights . Abstract Background: Mental health disorders, such as late-life depression and dementia, are a growing problem the aging population faces. Common treatment medications carry

2017 Pacific University EBM Capstone Project

794. Can Angiotensin-Converting Enzyme Inhibitors Slow the Progression of Cognitive Decline In Elderly Patients With Dementia?

Can Angiotensin-Converting Enzyme Inhibitors Slow the Progression of Cognitive Decline In Elderly Patients With Dementia? "Can Angiotensin-Converting Enzyme Inhibitors Slow the Progression of C" by Karielle Brugman < > > > > > Title Author Date of Graduation Summer 8-12-2017 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies Rights . Abstract Background: Dementia is a slow progressing neurodegenerative disease characterized by loss of executive functioning (...) in dementia patients. Conclusion: Current research on dementia progression and ACE inhibitors, as measured by cognitive assessment tools, have been shown to slow cognitive decline in elderly patients. Further research, preferably multiple, large randomized controlled human trials are necessary to determine the risk versus benefit of ACE inhibitor use. Keywords: Alzheimer’s disease, dementia, ACE inhibitors, angiotensin converting enzyme inhibitors, cognitive decline, renin-angiotensin system, RAS

2017 Pacific University EBM Capstone Project

795. Treatment options of arm fractures in the elderly

for Health Technology Assessment and Assessment of Social Services (SBU) has evaluated the effects, complications, health economic aspects and ethical considerations of arm fractures treatment in the elderly with a mean age above 60 years. The project originates from a proposal from the Swedish Orthopaedic Association. The systematic review also includes studies on how patients with osteoporosis experience participation in their care and their encounters with health care professionals. Using plaster (...) , Hoxha Ekstrom E, Josefsson PO, et al. Treatment of humerus fractures in the elderly: A systematic review covering effectiveness, safety, economic aspects and evolution of practice. PLoS One 2018;13:e0207815. Appendices Project group Experts Carl Ekholm (Associate Professor, University of Gothenburg and Senior Consultant in Orthopedics, Sahlgrenska University Hospital, Gothenburg) Per Olof Josefsson (Associate Professor, Lund University and Senior Consultant in Orthopedics, Skåne University Hospital

2017 Swedish Council on Technology Assessement

796. Impact of an Age-Adjusted Co-morbidity Index on Survival of Patients With Heart Failure Implanted With Cardiac Resynchronization Therapy Devices Full Text available with Trip Pro

Impact of an Age-Adjusted Co-morbidity Index on Survival of Patients With Heart Failure Implanted With Cardiac Resynchronization Therapy Devices Age is an adverse prognostic factor in patients with heart failure. We aimed to assess the impact of age and noncardiac co-morbidities in the outcome of patients undergoing cardiac resynchronization therapy (CRT), and determine which of these two factors is the most important predictor of survival. The study involved a single-center retrospective (...) assessment of 697 consecutive CRT implants during a 12-year period. Patient co-morbidity profile was assessed using the Charlson Co-morbidity Index (CCI) and the Charlson Age-Co-morbidity Index (CACI). Predictors of survival free from heart transplantation were assessed. CRT-related complications and cause of death analysis were assessed within tertiles of the CACI. During a mean follow-up of 1,813 ± 1,177 days, 347 patients (49.9%) died and 37 (5.3%) underwent heart transplantation. On multivariate Cox

2017 EvidenceUpdates

797. A randomized controlled trial of a combined self-management and exercise intervention for elderly people with osteoarthritis of the knee: the PLE2NO program (Abstract)

A randomized controlled trial of a combined self-management and exercise intervention for elderly people with osteoarthritis of the knee: the PLE2NO program To assess the effectiveness of a 12-week self-management and exercise intervention (the PLE2NO program) in elderly individuals with knee osteoarthritis.Randomized controlled trial.Four different community settings.Eighty individuals aged 60 years or older with clinical and radiographic knee osteoarthritis enrolled in the study.A combined (...) and upper limb flexibility, and handgrip strength.In all, 67 participants, mean age 69.1 ± 5.8 years, completed the study: 32 in the Educational Group and 35 in the Self-Management and Exercise Group. A significant group effect favorable to the Self-Management and Exercise Group was observed in the following variables: communication with the physicians ( P = .048), aerobic capacity ( P = .035), and functional lower limb strength ( P = .015). Although no significant group effect was detected, clinical

2017 EvidenceUpdates

798. Effects of Canagliflozin on Cardiovascular Biomarkers in Older Adults With Type 2 Diabetes Full Text available with Trip Pro

patients. These cardiac biomarker data provide support for the beneficial cardiovascular effect of sodium glucose co-transporter 2 inhibitors in T2DM. (A Safety and Efficacy Study of Canagliflozin in Older Patients [55 to 80 Years of Age] With Type 2 Diabetes Mellitus; NCT01106651).Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved. (...) Effects of Canagliflozin on Cardiovascular Biomarkers in Older Adults With Type 2 Diabetes Sodium glucose co-transporter 2 inhibitors may reduce cardiovascular and heart failure risk in patients with type 2 diabetes mellitus (T2DM).The goal of this study was to examine the effects of canagliflozin on cardiovascular biomarkers in older patients with T2DM.In 666 T2DM patients randomized to receive canagliflozin 100 or 300 mg or placebo, the study assessed the median percent change in serum N

2017 EvidenceUpdates

799. Effectiveness of a Timing and Coordination Group Exercise Program to Improve Mobility in Community-Dwelling Older Adults: A Randomized Clinical Trial Full Text available with Trip Pro

care) at improving function, disability, and walking ability of older adults.Cluster-randomized, single-blind intervention trial. Thirty-two independent living facilities, senior apartment buildings, and senior community centers were randomized to On the Move (16 sites; 152 participants) or usual care (16 sites; 146 participants). Participants were 65 years or older, able to ambulate independently with a gait speed of at least 0.60 m/s, able to follow 2-step commands, and were medically (...) Effectiveness of a Timing and Coordination Group Exercise Program to Improve Mobility in Community-Dwelling Older Adults: A Randomized Clinical Trial Timing and coordination exercises may be an important addition to community-based health promotion exercise programs to improve walking in older adults.To compare the effectiveness of the On the Move group exercise program, which focuses on the timing and coordination of movement, with a seated strength, endurance, and flexibility program (usual

2017 EvidenceUpdates

800. [Optical coherence tomography (OCT) for neovascular age-related macular degeneration as well as diabetic retinopathy with macular oedema]

[Optical coherence tomography (OCT) for neovascular age-related macular degeneration as well as diabetic retinopathy with macular oedema] Optische kohärenztomografie bei neovaskulärer altersbedingter makuladegeneration sowie beim makulaödem im rahmen der diabetischen retinopathie: abschlussbericht; auftrag D15-01 [Optical coherence tomography (OCT) for neovascular age-related macular degeneration as well as diabetic retinopathy with macular oedema] Optische kohärenztomografie bei neovaskulärer (...) altersbedingter makuladegeneration sowie beim makulaödem im rahmen der diabetischen retinopathie: abschlussbericht; auftrag D15-01 [Optical coherence tomography (OCT) for neovascular age-related macular degeneration as well as diabetic retinopathy with macular oedema] Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made

2017 Health Technology Assessment (HTA) Database.