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Feasibility and efficiency of concurrent chemoradiotherapy with capecitabine and cisplatin versus radiotherapy alone for elderly patients with locally advanced esophageal squamous cell carcinoma: Experience of two centers 29024498 2018 11 02 2018 11 13 1759-7714 9 1 2018 01 Thoracic cancer Thorac Cancer Feasibility and efficiency of concurrent chemoradiotherapy with capecitabine and cisplatin versus radiotherapy alone for elderly patients with locally advanced esophageal squamous cell carcinoma (...) : Experience of two centers. 59-65 10.1111/1759-7714.12536 The purpose of this retrospective study was to evaluate the feasibility and efficacy of definitive concurrent chemoradiotherapy (CCRT) with capecitabine and cisplatin for elderly patients with locally advanced esophageal squamous cell carcinoma. A total of 90 patients were included from two different centers. Forty-nine patients were treated with CCRT consisting of capecitabine (850 mg/m 2 , oral, twice a day for 1-14 days) and cisplatin (20 mg/m 2
Developing a multidisciplinary rehabilitation package following hip fracture and testing in a randomised feasibility study: Fracture in the Elderly Multidisciplinary Rehabilitation (FEMuR) Developing a multidisciplinary rehabilitation package following hip fracture and testing in a randomised feasibility study: Fracture in the Elderly Multidisciplinary Rehabilitation (FEMuR) Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page
Effect of Systematic Intensive Care Unit Triage on Long-term Mortality Among Critically Ill Elderly Patients in France: A Randomized Clinical Trial. Importance: The high mortality rate in critically ill elderly patients has led to questioning of the beneficial effect of intensive care unit (ICU) admission and to a variable ICU use among this population. Objective: To determine whether a recommendation for systematic ICU admission in critically ill elderly patients reduces 6-month mortality (...) compared with usual practice. Design, Setting, and Participants: Multicenter, cluster-randomized clinical trial of 3037 critically ill patients aged 75 years or older, free of cancer, with preserved functional status (Index of Independence in Activities of Daily Living ≥4) and nutritional status (absence of cachexia) who arrived at the emergency department of one of 24 hospitals in France between January 2012 and April 2015 and were followed up until November 2015. Interventions: Centers were randomly
Ear diseases and factors associated with ear infections among the elderly attending hospital in Arar city, Northern Saudi Arabia 29038714 2018 11 13 2008-5842 9 9 2017 Sep Electronic physician Electron Physician Ear diseases and factors associated with ear infections among the elderly attending hospital in Arar city, Northern Saudi Arabia. 5304-5309 10.19082/5304 Changes in the anatomical structures and function of the ear can result in ear diseases, and may affect all age groups including (...) the elderly as a result of aging. To identify the frequency and types of ear diseases among the elderly attending Abdullah bin Abdul-Aziz bin Musa'ed Al Saud hospital, Arar city, in the Northern Province of KSA, and factors associated with ear infections among them. This cross-sectional hospital based study conducted from December 2016 through May 2017 included 138 elderly participants. A questionnaire was designed for collecting data about socio-demographic variables, the frequency and types of ear
Epidemiology of senile prostatic enlargement among elderly men in Arar, Kingdom of Saudi Arabia 29038720 2018 11 13 2008-5842 9 9 2017 Sep Electronic physician Electron Physician Epidemiology of senile prostatic enlargement among elderly men in Arar, Kingdom of Saudi Arabia. 5349-5353 10.19082/5349 Senile prostatic enlargement due to benign prostatic hyperplasia (BPH) is a common problem among older men, and is responsible for considerable disability. This study was conducted to determine (...) the prevalence and determinants of the clinically diagnosed prostatic enlargement among elderly men in Arar, Northern Saudi Arabia. This cross-sectional study was carried out on all consented elderly males attending the outpatient clinic of the urology department of Arar Central Hospital from February 2017 to July 30, 2017. Each participant underwent a general examination and digital per rectal to detect general chronic diseases, obesity and prostatic enlargement. Data were analyzed by SPSS version 16, using
Treatment and relative survival in very elderly patients with DLBCL in The Netherlands: a population-based study, 1989 to 2015 29297513 2018 11 13 2473-9529 1 21 2017 Sep 26 Blood advances Blood Adv Treatment and relative survival in very elderly patients with DLBCL in The Netherlands: a population-based study, 1989 to 2015. 1839-1841 10.1182/bloodadvances.2017011031 Dinmohamed Avinash G AG 0000-0002-4767-6716 Department of Research, Netherlands Comprehensive Cancer Organisation, Utrecht
Hemocoagulase might not control but worsen gastrointestinal bleeding in an elderly patient with type II respiratory failure 29034344 2018 11 13 2415-1289 2 2017 Translational gastroenterology and hepatology Transl Gastroenterol Hepatol Hemocoagulase might not control but worsen gastrointestinal bleeding in an elderly patient with type II respiratory failure. 71 10.21037/tgh.2017.08.08 Hemocoagulase has been successfully used for the management of bleeding in patients undergoing surgery. Local (...) spray of hemocoagulase during endoscopic therapy may be effective for the management of gastrointestinal bleeding. In China, intravenous infusion of hemocoagulase is given by some physicians for the treatment of gastrointestinal bleeding. However, the potential adverse events secondary to hemocoagulase, such as hypofibrinogenemia, are poorly recognized. In this paper, we reported an elderly patient with type II respiratory failure in whom hemocoagulase might induce hypofibrinogenemia and further
A randomized controlled trial of a combined self-management and exercise intervention for elderly people with osteoarthritis of the knee: the PLE2NO program 28714343 2017 07 17 2017 07 17 1477-0873 2017 Jul 01 Clinical rehabilitation Clin Rehabil A randomized controlled trial of a combined self-management and exercise intervention for elderly people with osteoarthritis of the knee: the PLE(2)NO program. 269215517718892 10.1177/0269215517718892 To assess the effectiveness of a 12-week self (...) -management and exercise intervention (the PLE(2)NO program) in elderly individuals with knee osteoarthritis. Randomized controlled trial. Four different community settings. Eighty individuals aged 60 years or older with clinical and radiographic knee osteoarthritis enrolled in the study. A combined self-management and exercise intervention (treatment group) and an educational intervention (control group). The primary outcomes were pain and other knee osteoarthritis symptoms (swelling, crackling
Intergenerational Programs? Effect on the Mental Health of the Elderly "Intergenerational Programs’ Effect on the Mental Health of the Elderly" by Alysia Hagert < > > > > Title Author Date of Graduation Summer 8-12-2017 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies Rights . Abstract Background: Mental health disorders, such as late-life depression and dementia, are a growing problem the aging population faces. Common treatment medications carry (...) with them many negative aspects. Intergenerational programs are being sought out as an alternative or additional therapy to medication. These programs are focused on strengthening intergenerational relationships, improving health and quality of life, and restoring generational roles. This review looks at the effect intergenerational programs have on the mental health of the aged population. Methods: An exhaustive search of available medical literature was performed using MEDLINE-Ovid, Web of Knowledge
Can Angiotensin-Converting Enzyme Inhibitors Slow the Progression of Cognitive Decline In Elderly Patients With Dementia? "Can Angiotensin-Converting Enzyme Inhibitors Slow the Progression of C" by Karielle Brugman < > > > > > Title Author Date of Graduation Summer 8-12-2017 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies Rights . Abstract Background: Dementia is a slow progressing neurodegenerative disease characterized by loss of executive functioning (...) in dementia patients. Conclusion: Current research on dementia progression and ACE inhibitors, as measured by cognitive assessment tools, have been shown to slow cognitive decline in elderly patients. Further research, preferably multiple, large randomized controlled human trials are necessary to determine the risk versus benefit of ACE inhibitor use. Keywords: Alzheimer’s disease, dementia, ACE inhibitors, angiotensin converting enzyme inhibitors, cognitive decline, renin-angiotensin system, RAS
Effect of Adjuvant Chemotherapy on Elderly Colorectal Cancer Patients: Lack of Evidence 29071260 2018 11 13 2296-3774 4 1-2 2017 Sep Gastrointestinal tumors Gastrointest Tumors Effect of Adjuvant Chemotherapy on Elderly Colorectal Cancer Patients: Lack of Evidence. 11-19 10.1159/000479318 Adjuvant chemotherapy has become the standard form of treatment for all patients with stage III colorectal cancer and is also recommended for patients with stage II disease and defined risk factors. However (...) , clinical studies that evaluate the effect of adjuvant treatment regimens have a selection bias in favor of younger patients, so that even retrospective subgroup analyses cannot define the best therapeutic procedure in elderly patients with comorbidities. As long as the role of adjuvant chemotherapy in elderly colorectal cancer patients is not investigated in comprehensive trials, no clear recommendations are possible. An exploratory review of the relevant literature revealed that a formal meta-analysis
Self-efficacy of foot care behaviour of elderly patients with diabetes 29423123 2018 11 13 1985-207X 12 2 2017 Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia Malays Fam Physician Self-efficacy of foot care behaviour of elderly patients with diabetes. 2-8 Elderly patients with diabetes are at a high risk of contracting diabetic foot problems. Self-efficacy is essential to help improve foot care behaviour. To identify levels of self-efficacy (...) and foot care behaviour and their relationship with demographic characteristics in elderly patients with diabetes. A cross-sectional study was conducted in two general hospitals in Malaysia from May to June 2015. Diabetes patients aged 60 years with specific inclusion criteria were invited to participate in this study. The respondents were interviewed using a set of validated questionnaires. Data were analysed with descriptive and inferential statistics (multiple linear regression) using Statistical
Elderly peoplesâ€™ experiences of nursing homes in Bam city: A qualitative study 28979736 2018 11 13 2008-5842 9 8 2017 Aug Electronic physician Electron Physician Elderly peoples' experiences of nursing homes in Bam city: A qualitative study. 5015-5023 10.19082/5015 With the increasing number of elderly, especially in recent decades, transfer to nursing homes and the number of centers has also increased but experiences and problems of elders in these centers is less considered. So, the goal (...) of this study is to explore the Elderly peoples' experiences of nursing homes. The current research was performed using a phenomenological approach in 2016. Participation in the study is comprised of the elderly residents in a nursing home in Bam city who were selected based on an objective-oriented approach. The sampling was done until data saturation. Data collection methods were observation and an unstructured and in-depth interview. Data were analyzed using seven-stage Colaizzi process. In total
Challenges in Decision Making in Elderly Patients with Gastrointestinal Malignancies 29034257 2018 08 01 2297-4725 33 4 2017 Aug Visceral medicine Visc Med Challenges in Decision Making in Elderly Patients with Gastrointestinal Malignancies. 281-283 10.1159/000478806 Wedding Ulrich U Department of Internal Medicine II (Haematology, Oncology, Palliative Care), University Hospital Jena, Jena, Germany. Audisio Riccardo A RA Department of Surgery, University of Liverpool, St Helens Teaching (...) Hospital, St Helens, UK. Richter Konrad Klaus KK Department of Surgery, Southland Hospital, Invercargill, New Zealand. Dunedin Hospital and School of Medicine, Dunedin, New Zealand. Rostoft Siri S Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway. University of Oslo, Oslo, Norway. eng Journal Article 2017 08 22 Switzerland Visc Med 101681546 2297-4725 2017 10 17 6 0 2017 10 17 6 0 2017 10 17 6 1 ppublish 29034257 10.1159/000478806 vis-0033-0281 PMC5624260
Challenges in Decision Making in Elderly Patients with Gastrointestinal Malignancies 29034251 2018 08 01 2297-4725 33 4 2017 Aug Visceral medicine Visc Med Challenges in Decision Making in Elderly Patients with Gastrointestinal Malignancies. 244 10.1159/000480254 Wedding Ulrich U Department of Internal Medicine II (Haematology, Oncology, Palliative Care), University Hospital Jena, Jena, Germany. Richter Konrad Klaus KK Department of Surgery, Southland Hospital, Invercargill, New Zealand
Ulinastatin did not reduce mortality in elderly multiple organ failure patients: a retrospective observational study in a single center ICU 29445506 2018 11 13 2052-8817 5 1 2018 01 Acute medicine & surgery Acute Med Surg Ulinastatin did not reduce mortality in elderly multiple organ failure patients: a retrospective observational study in a single center ICU. 90-97 10.1002/ams2.304 Our aim was to evaluate the effect of ulinastatin on 28-day mortality in patients who developed multiple organ (...) showed that ulinastatin was not associated with 28-day mortality (odds ratio = 1.22; 95% confidence interval, 0.54-2.79). Moreover, ulinastatin did not reduce the mortality in patients with sepsis (odds ratio = 1.92; 95% confidence interval, 0.52-7.13). However, ICU-free days and ventilator-free days was significantly fewer in the ulinastatin group than control group. In this retrospective observational study, ulinastatin was not associated with mortality in elderly patients with established MOF
Erythropoiesis-stimulating agents in elderly patients with anemia: response and cardiovascular outcomes 29296795 2018 11 13 2473-9529 1 19 2017 Aug 22 Blood advances Blood Adv Erythropoiesis-stimulating agents in elderly patients with anemia: response and cardiovascular outcomes. 1538-1545 10.1182/bloodadvances.2017007559 A specific cause of anemia cannot be identified in many elderly patients. Erythropoiesis-stimulating agents (ESAs) may play a role in treating these patients with anemia (...) of unknown etiology (AUE). This study examines hemoglobin and cardiovascular outcomes among elderly anemic patients treated with ESAs. We conducted a retrospective cohort study that included all anemic patients older than age 60 years who had erythropoietin (EPO) measured between 2005 and 2013 at a single center. Three independent reviewers used defined criteria to assign each patient's anemia to 1 of 4 groups: chronic kidney disease (CKD), myelodysplastic syndrome, AUE, or other etiology. Logistic
Association between vitamin D deficiency and heart failure risk in the elderly 28817241 2018 10 25 2018 11 13 2055-5822 5 1 2018 02 ESC heart failure ESC Heart Fail Association between vitamin D deficiency and heart failure risk in the elderly. 63-74 10.1002/ehf2.12198 The aim of this study was to evaluate the association between vitamin D deficiency and risk of heart failure in elderly patients of cardiology outpatient clinics. A cross-sectional study with an analytical approach was employed (...) . Clinical data were collected from the elderly from August 2015 to February 2016. The dependent variable was the risk of heart failure; the independent variable was vitamin D deficiency; and intervening factors were age, gender, education, ethnicity, hypertension, diabetes mellitus, hypothyroidism, renal failure, dementia, stroke, dyslipidaemia, depression, smoking, alcoholism, obesity, andropause, and cardiac arrhythmia. To analyse the association between vitamin D deficiency and risk of heart
Perioperative Management of Elderly Patients with Gastrointestinal Malignancies: The Contribution of Anesthesia 29034255 2018 11 13 2297-4725 33 4 2017 Aug Visceral medicine Visc Med Perioperative Management of Elderly Patients with Gastrointestinal Malignancies: The Contribution of Anesthesia. 267-274 10.1159/000475611 Elderly patients suffering from gastrointestinal malignancies are particularly prone to perioperative complications. Elderly patients often present with reduced physiological (...) reserves, and comorbidities can limit treatment options and promote complications. Surgeons and anesthesiologists must be aware of strategies required to deal with this vulnerable subgroup. We provide a brief review of current and emerging perioperative strategies for the treatment of elderly patients with gastrointestinal malignancies and frequent comorbidities. Especially in combination with advanced age, the effects of malignancies can be devastating, bringing new health challenges, exacerbating