Latest & greatest articles for elderly

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Top results for elderly

41. Effects of implementing Pressure Ulcer Prevention Guideline (PUPPG) in the prevention of pressure ulcers among hospitalized elderly patients

Effects of implementing Pressure Ulcer Prevention Guideline (PUPPG) in the prevention of pressure ulcers among hospitalized elderly patients Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration

2019 PROSPERO

42. Impact of pharmacist-led home medicines review services on drug related problems among elderly population: a systematic review

Impact of pharmacist-led home medicines review services on drug related problems among elderly population: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any

2019 PROSPERO

43. Effective non-drug interventions for improving cognitive status of elderly with mild cognitive impairment: a systematic review

Effective non-drug interventions for improving cognitive status of elderly with mild cognitive impairment: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any

2019 PROSPERO

44. Effect of perioperative dexmedetomidine on postoperative mortality and morbidity of elderly patients: a meta-analysis

Effect of perioperative dexmedetomidine on postoperative mortality and morbidity of elderly patients: a meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated

2019 PROSPERO

45. Outcomes of soft tissue closure following open lower limb fractures in the elderly: a systematic review comparing flap reconstruction with other methods of wound closure

Outcomes of soft tissue closure following open lower limb fractures in the elderly: a systematic review comparing flap reconstruction with other methods of wound closure Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability

2019 PROSPERO

46. Impact of immune therapy in elderly patients with non-small cell lung cancer

Impact of immune therapy in elderly patients with non-small cell lung cancer Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email

2019 PROSPERO

47. Does the efficacy of postoperative pain management in the elderly patient influence their quality of recovery? A systematic review

Does the efficacy of postoperative pain management in the elderly patient influence their quality of recovery? A systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record

2019 PROSPERO

48. Effectiveness of surgical versus conservative treatment of distal radius fracture in elderly patients: a systematic review and meta-analysis

Effectiveness of surgical versus conservative treatment of distal radius fracture in elderly patients: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration

2019 PROSPERO

49. Comparative tolerability of duloxetine in the elderly and in adults: a systematic review and meta-analysis of individual participant analysis

Comparative tolerability of duloxetine in the elderly and in adults: a systematic review and meta-analysis of individual participant analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content

2019 PROSPERO

50. Comparative effectiveness and safety of transcatheter aortic valve implantation (TAVI) versus surgical aortic valve replacement (SAVR) in elderly (&gt 75 years) patients with severe aortic stenosis: a systematic review and meta-analysis

Comparative effectiveness and safety of transcatheter aortic valve implantation (TAVI) versus surgical aortic valve replacement (SAVR) in elderly (> 75 years) patients with severe aortic stenosis: a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission

2019 PROSPERO

51. Effect of Exercise Intervention on Functional Decline in Very Elderly Patients During Acute Hospitalization: A Randomized Clinical Trial

Effect of Exercise Intervention on Functional Decline in Very Elderly Patients During Acute Hospitalization: A Randomized Clinical Trial Functional decline is prevalent among acutely hospitalized older patients. Exercise and early rehabilitation protocols applied during acute hospitalization can prevent functional and cognitive decline in older patients.To assess the effects of an innovative multicomponent exercise intervention on the functional status of this patient population.A single-center (...) , single-blind randomized clinical trial was conducted from February 1, 2015, to August 30, 2017, in an acute care unit in a tertiary public hospital in Navarra, Spain. A total of 370 very elderly patients undergoing acute-care hospitalization were randomly assigned to an exercise or control (usual-care) intervention. Intention-to-treat analysis was conducted.The control group received usual-care hospital care, which included physical rehabilitation when needed. The in-hospital intervention included

2018 EvidenceUpdates

52. Effect of Physical Disability on Mortality in Elderly Patients of >/=80 Years of Age Undergoing Percutaneous Coronary Intervention

Effect of Physical Disability on Mortality in Elderly Patients of >/=80 Years of Age Undergoing Percutaneous Coronary Intervention Functional decrease has been linked with adverse events in different clinical contexts. The predictive role of activity of daily living status as assessed by the Barthel index (BI) in elderly patients who underwent percutaneous coronary intervention (PCI) has not been investigated, yet. In this study, a total of 616 patients (≥80 years) who underwent PCI between (...) of daily living should be incorporated into the risk stratification of elderly patients with coronary artery disease.Copyright © 2018 Elsevier Inc. All rights reserved.

2018 EvidenceUpdates

53. Improved Survival by Adding Lomustine to Conventional Chemotherapy for Elderly Patients With AML Without Unfavorable Cytogenetics: Results of the LAM-SA 2007 FILO Trial

Improved Survival by Adding Lomustine to Conventional Chemotherapy for Elderly Patients With AML Without Unfavorable Cytogenetics: Results of the LAM-SA 2007 FILO Trial Acute myeloid leukemia (AML) in elderly patients has a poor prognosis. In an attempt to improve outcome for these patients, the prospective open-label phase III LAM-SA 2007 (Adding Lomustine to Chemotherapy in Older Patients With Acute Myelogenous Leukemia (AML), and Allogeneic Transplantation for Patients From 60 to 65 Years (...) , were significantly higher in the ICL arm ( P = .04), and fewer patients required a second treatment after ICL.Adding lomustine to standard chemotherapy significantly improved the outcome of elderly patients with AML.

2018 EvidenceUpdates

54. Cost-effectiveness of the HiBalance training program for elderly with Parkinson`s disease: analysis of data from a randomized controlled trial

Cost-effectiveness of the HiBalance training program for elderly with Parkinson`s disease: analysis of data from a randomized controlled trial To determine the cost-effectiveness of the HiBalance training program for managing Parkinson's disease (PD)-related balance and gait disorders.Cost comparison design following the randomized controlled trial comparing a novel balance training intervention with care as usual.A total of 100 participants with mild-moderate PD were randomized to either

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2018 EvidenceUpdates

55. Effect of Aspirin on All-Cause Mortality in the Healthy Elderly. (PubMed)

Effect of Aspirin on All-Cause Mortality in the Healthy Elderly. In the primary analysis of the Aspirin in Reducing Events in the Elderly (ASPREE) trial, now published in the Journal, we report that the daily use of aspirin did not provide a benefit with regard to the primary end point of disability-free survival among older adults. A numerically higher rate of the secondary end point of death from any cause was observed with aspirin than with placebo.From 2010 through 2014, we enrolled

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2018 NEJM

56. Effect of Aspirin on Disability-free Survival in the Healthy Elderly. (PubMed)

Effect of Aspirin on Disability-free Survival in the Healthy Elderly. Information on the use of aspirin to increase healthy independent life span in older persons is limited. Whether 5 years of daily low-dose aspirin therapy would extend disability-free life in healthy seniors is unclear.From 2010 through 2014, we enrolled community-dwelling persons in Australia and the United States who were 70 years of age or older (or ≥65 years of age among blacks and Hispanics in the United States) and did (...) 1000 person-years in the placebo group), dementia, or persistent physical disability. The rate of major hemorrhage was higher in the aspirin group than in the placebo group (3.8% vs. 2.8%; hazard ratio, 1.38; 95% CI, 1.18 to 1.62; P<0.001).Aspirin use in healthy elderly persons did not prolong disability-free survival over a period of 5 years but led to a higher rate of major hemorrhage than placebo. (Funded by the National Institute on Aging and others; ASPREE ClinicalTrials.gov number

2018 NEJM

57. Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly. (PubMed)

Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly. Aspirin is a well-established therapy for the secondary prevention of cardiovascular events. However, its role in the primary prevention of cardiovascular disease is unclear, especially in older persons, who have an increased risk.From 2010 through 2014, we enrolled community-dwelling men and women in Australia and the United States who were 70 years of age or older (or ≥65 years of age among blacks and Hispanics

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2018 NEJM

58. The validation of the PRISMA-7 questionnaire in community-dwelling elderly people living in Antalya, Turkey (PubMed)

The validation of the PRISMA-7 questionnaire in community-dwelling elderly people living in Antalya, Turkey The screening of frailty in older adults is an important issue in the preventive approach in medicine. Frailty is one of the leading causes of morbidity and premature mortality in older adults.The aim of this study was to validate the PRISMA-7 questionnaire in community-dwelling elderly people living in Antalya, Turkey.This study was cross-sectional and observational in nature (...) was translated back by two translators to English. The translation was then compiled to one text and compared with the original text. After agreement on the translation, both translations were piloted in 10 elderly people. The final form has been applied in this study. Data of the ten piloted patients have not been included into the dataset. Data were analyzed by IBM-SPSS version 22, using descriptive statistics, Pearson product-moment correlation, and receiver operator characteristic (ROC) analysis

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2018 Electronic physician

59. Cisplatin-Based First-Line Treatment of Elderly Patients With Advanced Non-Small-Cell Lung Cancer: Joint Analysis of MILES-3 and MILES-4 Phase III Trials

Cisplatin-Based First-Line Treatment of Elderly Patients With Advanced Non-Small-Cell Lung Cancer: Joint Analysis of MILES-3 and MILES-4 Phase III Trials Purpose To test the efficacy of adding cisplatin to first-line treatment for elderly patients with advanced non-small-cell lung cancer (NSCLC) within a combined analysis of two parallel phase III trials, MILES-3 and MILES-4. Patients and Methods Patients with advanced NSCLC who were older than age 70 years with Eastern Cooperative Oncology (...) score of quality of life was not improved, whereas progression-free survival (HR, 0.76; 95% CI, 0.63 to 0.92; P = .005) and objective response rate (15.5% v 8.5%; P = .02) were significantly better. Significantly more severe hematologic toxicity, fatigue, and anorexia were found with cisplatin. Conclusion The addition of cisplatin to single-agent chemotherapy does not significantly prolong overall survival, and it does not improve global health status score of quality of life in elderly patients

2018 EvidenceUpdates

60. Caregiver-Based Interventions to Optimize Medication Safety in Vulnerable Elderly Adults: A Systematic Evidence-Based Review

Caregiver-Based Interventions to Optimize Medication Safety in Vulnerable Elderly Adults: A Systematic Evidence-Based Review To study the effect of caregiver-focused interventions to support medication safety in older adults with chronic disease.Systematic review.Studies published before January 31, 2017, searched using Ovid Medline, PubMed, EMBASE, Scopus, CINAHL, PsycINFO, and Google Scholar.Caregivers with or without a care recipient.Inclusion criteria: interventions focused on caregivers

2018 EvidenceUpdates