Latest & greatest articles for elderly

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on elderly or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on elderly and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for elderly

281. Haloperidol Use Among Elderly Patients Undergoing Surgery: A Retrospective 1-Year Study in a Hospital Population (PubMed)

Haloperidol Use Among Elderly Patients Undergoing Surgery: A Retrospective 1-Year Study in a Hospital Population Haloperidol, frequently used for delirium, can lead to serious side effects, of which QTc prolongation is the most worrisome since it is associated with an increased risk of fatal cardiac arrhythmia.The aim of this study was to measure the frequency of haloperidol use after procedures in patients aged ≥65 years in a hospital in the Netherlands.This was a retrospective study among (...) patients hospitalized in the Netherlands who were aged ≥65 years and who underwent a procedure between January 2008 and January 2009. The hospital's electronic drug database was used to identify the use of haloperidol during hospital admission.A total of 7782 procedures took place in 5946 elderly patients, and 1357 patients were readmitted for a second procedure in the same year. The overall frequency of haloperidol use was 5.4 %. Procedures were classified as elective (90 %) and as major (18

Full Text available with Trip Pro

2016 Drugs - real world outcomes

282. Sequential vs alternating administration of VMP and Rd in elderly patients with newly diagnosed MM (PubMed)

Sequential vs alternating administration of VMP and Rd in elderly patients with newly diagnosed MM Bortezomib plus melphalan and prednisone (VMP) and lenalidomide plus low-dose dexamethasone (Rd) are 2 standards of care for elderly untreated multiple myeloma (MM) patients. We planned to use VMP and Rd for 18 cycles in a sequential or alternating scheme. Patients (233) with untreated MM, >65 years, were randomized to receive 9 cycles of VMP followed by 9 cycles of Rd (sequential scheme; n = 118

Full Text available with Trip Pro

2016 EvidenceUpdates

283. Myofascial Pain Syndrome in the Elderly and Self-Exercise: A Single-Blind, Randomized, Controlled Trial. (PubMed)

Myofascial Pain Syndrome in the Elderly and Self-Exercise: A Single-Blind, Randomized, Controlled Trial. This study aimed to demonstrate the effect of self-exercise with a therapeutic inflatable ball (SEIB) in elderly patients with myofascial pain syndrome.Single-blind, randomized, controlled noninferiority trial.University campus.Forty elderly patients with myofascial pain syndrome completed the study. They were randomly allocated to SEIB (n = 22; mean age, 70.23 ± 6.11 years) or ultrasound (...)  = 0.159). In within-group comparisons, both groups presented significant differences in VAS (SEIB after 1 week and US after 1 week), PPT (SEIB after 3 weeks and US after 4 weeks), and CLF (SEIB after 4 weeks and US after 4 weeks) compared with baseline values.SEIB for 4 weeks has an effect similar to that of US for desensitizing myofascial pain and increasing joint flexibility. High accessibility and low cost would make SEIB a practical self-treatment method in elderly patients with myofascial pain

Full Text available with Trip Pro

2016 Journal of alternative and complementary medicine (New York, N.Y.)

284. Severe hypocalcemia and prolonged QT interval due to denosumab in an elderly woman with rheumatoid arthritis and chronic kidney disease (PubMed)

Severe hypocalcemia and prolonged QT interval due to denosumab in an elderly woman with rheumatoid arthritis and chronic kidney disease 27733948 2018 11 13 2147-9720 3 3 2016 Sep European journal of rheumatology Eur J Rheumatol Severe hypocalcemia and prolonged QT interval due to denosumab in an elderly woman with rheumatoid arthritis and chronic kidney disease. 144-145 Oiwa Hiroshi H Department of Rheumatology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan. Mokuda Sho S

Full Text available with Trip Pro

2016 European journal of rheumatology

285. Patterns of Treatment Sequences in Chemotherapy and Targeted Biologics for Metastatic Colorectal Cancer: Findings from a Large Community-Based Cohort of Elderly Patients (PubMed)

Patterns of Treatment Sequences in Chemotherapy and Targeted Biologics for Metastatic Colorectal Cancer: Findings from a Large Community-Based Cohort of Elderly Patients Over the last decade, multiple chemotherapies/targeted biologics have been approved for metastatic colorectal cancer (mCRC). However, evidence is limited with regards to the array of treatments received by mCRC patients.This study examines treatment sequences (first- to third-line chemotherapy/targeted biologics (...) ) and the factors associated with first-line targeted biologics and common treatment sequences for elderly mCRC patients treated in a community setting.A retrospective cohort study was conducted in mCRC patients diagnosed from January 2004 through December 2009 using the Surveillance, Epidemiology and End Results Medicare-linked database. The treatment sequences administered to elderly mCRC patients were empirically identified.Of 4418 mCRC patients who received treatment, 1370 (31 %) received first, second

Full Text available with Trip Pro

2016 Drugs - real world outcomes

286. Effects of Tai Chi Chuan on cognition of elderly women with mild cognitive impairment. (PubMed)

Effects of Tai Chi Chuan on cognition of elderly women with mild cognitive impairment. To detect the effects of Tai Chi Chuan practice on the cognition of elderly subjects with Mild Cognitive Impairment.This is a pilot study with 26 elderly patients (mean age of 74 years) with Mild Cognitive Impairment. The evaluation instruments were Subjective Memory Complaint Scale (SMC), Rivermead Behavioral Memory Test (RBMT) and Digit Span Forward and Backward (DSF and DSB) from the Wechsler Adult (...) ). The Control Group showed no significant differences in the cognitive tests during the study. There was a significant correlation between the Tai Chi Chuan Learning Test and RBMT (p = 0.008), showing that patients with a better performance in exercising TCC also showed a better performance in memory.In this study, a six-month program of Tai Chi Chuan afforded a significant improvement of the performance of memory complaints in the elderly with Mild Cognitive Impairment. Additional randomized studies

Full Text available with Trip Pro

2016 Einstein (Sao Paulo, Brazil)

287. Correlation between two physical activity programs in the gait of sedentary elderly subjects. (PubMed)

Correlation between two physical activity programs in the gait of sedentary elderly subjects. To assess the effect of exercise on gait using two different programs: a group of aerobic exercises (Group A, n = 18) and a group of flexibility and balance exercises (Group B, n = 19).A casualized controlled study, in which each sample controlled itself, was undertaken. The sample comprised 37 male and female subjects, aged from 60 to 90 years, from the outpatient clinic of the Geriatrics Unit (...) of Hospital das Clínicas of Faculdade de Medicina of Universidade de São Paulo; the patients were sedentary and had not exercised regularly during the past six months.Improvement of gait was seen mainly in the group that did specific exercises.The results of this study underline the importance of physical exercises in sedentary elderly subjects, but show the need for programming the exercises towards specific goals, which can optimize the results of this tool of health promotion for the elderly.

Full Text available with Trip Pro

2016 Einstein (Sao Paulo, Brazil)

288. Aquatic physical therapy as a treatment modality in healthcare for non-institutionalized elderly persons: a systematic review. (PubMed)

Aquatic physical therapy as a treatment modality in healthcare for non-institutionalized elderly persons: a systematic review. To review scientific literature pertaining to aquatic physical therapy in the elderly and institutionalized population.A qualitative systematic review of electronic databases MEDLINE and LILACS, with the topic index terms: "hydrotherapy," "homes for the aged or residential facilities," and "aged. In light of the lack of studies carried out on the institutionalized (...) population, we opted for reviewing literature on the effectiveness of this modality of physical therapy treatment on the non-institutionalized elderly population in order to produce knowledge that can be critically analyzed according to its potential applicability for the institutionalized population. The methodological quality of the studies was assessed using the Delphi listing.Of the 27 studies analyzed by their abstracts, 10 studies were excluded since they did not correspond to the eligibility

Full Text available with Trip Pro

2016 Einstein (São Paulo, Brazil)

289. The importance of HDL-C and CRP in cardiovascular risk evaluation in longevous elderly individuals. (PubMed)

The importance of HDL-C and CRP in cardiovascular risk evaluation in longevous elderly individuals. The association between total mortality, lipoproteinS, and inflammatory markers, and their implications with aging and longevity are often controversial. Among the most often studied markers are low HDL cholesterol and high C-reactive protein. Particularly in octogenarians, it is expected that the impact of the inclusion of HDL cholesterol and C-reactive protein will improve the stratification (...) an inverse association between HDL cholesterol and total mortality, and between cardiovascular mortality and C-reactive protein, as well as a positive association between C-reactive protein and mortality in longevous individuals. C-reactive protein and HDL cholesterol displayed promising characteristics as predictors of cardiovascular mortality in longevous elderly persons.

Full Text available with Trip Pro

2016 Einstein (São Paulo, Brazil)

290. [EPIDEMIOLOGY OF FALLS IN THE NON-INSTITUTIONALIZED SPANISH ELDERLY POPULATION, SYSTEMATIC REVIEW 2014]. (PubMed)

[EPIDEMIOLOGY OF FALLS IN THE NON-INSTITUTIONALIZED SPANISH ELDERLY POPULATION, SYSTEMATIC REVIEW 2014]. OBJECTIVE To identify scientific publications about falls among non-institutionalized Spanish elderly population and to summarize the study findings which analysed the incidence, the risk factors and the consequences of the falls in the geriatric spanish population aged 65 years and over who lives institutionalized in our country.Systematic review of the epidemiological observational studies (...) was between 2.7 to 4.5 drugs per day. The fear of falling that had the elderly population non-institutionalized was between 44.7 % and 49.4 %. The vast majority of falls occurred at home, with percentages between 55.1 % and 61 %. Between 30 % and 55.1 % of people who suffered falls maintained health care contact immediately and the fractures prevalence was between 0 % and 26.1 %. CONCLUSTON: It can be confirmed that the falls prevalence in the spanish elderly population is high, so the need ofnew

2016 Revista de enfermería (Barcelona, Spain)

291. Cost-effectiveness study: Colorectal cancer screening is cost-effective in the elderly who have had less intense prior screening, high baseline risk of colorectal cancer and less comorbidities

Cost-effectiveness study: Colorectal cancer screening is cost-effective in the elderly who have had less intense prior screening, high baseline risk of colorectal cancer and less comorbidities Colorectal cancer screening is cost-effective in the elderly who have had less intense prior screening, high baseline risk of colorectal cancer and less comorbidities | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your (...) is cost-effective in the elderly who have had less intense prior screening, high baseline risk of colorectal cancer and less comorbidities Article Text Therapeutics/Prevention Cost-effectiveness study Colorectal cancer screening is cost-effective in the elderly who have had less intense prior screening, high baseline risk of colorectal cancer and less comorbidities Mark Jenkins Statistics from Altmetric.com Commentary on: van Hees F , Saini SD , Lansdorp-Vogelaar I , et al . Personalizing colonoscopy

2016 Evidence-Based Medicine (Requires free registration)

292. Systematic review: Training programmes and mealtime assistance may improve eating performance for elderly long-term care residents with dementia

Systematic review: Training programmes and mealtime assistance may improve eating performance for elderly long-term care residents with dementia Training programmes and mealtime assistance may improve eating performance for elderly long-term care residents with dementia | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please (...) see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Training programmes and mealtime assistance may improve eating performance for elderly long-term care residents

2016 Evidence-Based Nursing

293. Evaluation and Management of Asthma in the Elderly

Evaluation and Management of Asthma in the Elderly AMERICANTHORACICSOCIETY DOCUMENTS AnOf?cialAmericanThoracicSocietyWorkshopReport:Evaluation andManagementofAsthmaintheElderly Gwen S. Skloot, Paula J. Busse, Sidney S. Braman, Elizabeth J. Kovacs, Anne E. Dixon, Carlos A. Vaz Fragoso, Nicola Scichilone, Y. S. Prakash, Christina M. Pabelick, Sameer K. Mathur, Nicola A. Hanania, Wendy C. Moore, PeterG.Gibson,SusanZieman,andBetinaB.Ragless;onbehalfoftheATSadhocCommitteeonAsthmaintheElderly (...) . CorrespondenceandrequestsforreprintsshouldbeaddressedtoGwenS.Skloot,M.D.,DivisionofPulmonary,CriticalCare,andSleepMedicine,Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029. E-mail: gwen.skloot@mssm.edu Ann Am Thorac Soc Vol 13, No 11, pp 2064–2077, Nov 2016 Copyright© 2016 by the American Thoracic Society DOI: 10.1513/AnnalsATS.201608-658ST Internet address: www.atsjournals.org Contents Overview Introduction Methods Results UpdateontheEpidemiologyofasthma in the elderly (AIE) Update on the Effects

2016 American Thoracic Society

294. [Sexually transmitted diseases among the elderly: a systematic review]. (PubMed)

[Sexually transmitted diseases among the elderly: a systematic review]. The prolongation of an active sexual life in addition to unsafe practices are reflected in the possibility of the occurrence of STDs among the elderly. The scope of this study is to analyze the evolving trend of STDs among the elderly in Brazil and in the world and also to identify the main issues addressed in the literature, providing data that can support public policies that address the health of the elderly

Full Text available with Trip Pro

2015 Ciência & saúde coletiva

295. [Use of the Mini-Mental State Examination in research on the elderly in Brazil: a systematic review]. (PubMed)

[Use of the Mini-Mental State Examination in research on the elderly in Brazil: a systematic review]. The Mini-Mental State Examination (MMSE) is the most widely used cognitive screening test around the world. In Brazil, different MMSE versions and many cut-off points have been used. A systematic review of papers indexed in Scielo was conducted in order to analyze use of the MMSE in Brazilian empirical studies with elderly people. To search for these texts, the complete name of the instrument (...) and its abbreviation were used. A growth trend in the scientific production during the 1998 to 2013 period was observed. Eleven versions of the MMSE were identified and the Bertolucci et al. version was the most cited. Over half of the studies used schooling as the criteria to establish cut-off points. The studies were predominantly conducted using samples recruited from large cities in the Southeastern region and in the community. Despite the growing trend of research with the elderly using the MMSE

Full Text available with Trip Pro

2015 Ciência & saúde coletiva

296. Potentially Inappropriate Medications in the Elderly in Korean Long-Term Care Facilities (PubMed)

Potentially Inappropriate Medications in the Elderly in Korean Long-Term Care Facilities Elderly residents of long-term care facilities are more vulnerable to being prescribed inappropriate medications because of the high incidence of co-medication in this population resulting from the presence of multiple chronic diseases and also age-related changes in pharmacokinetics and pharmacodynamics.We evaluated the frequency of potentially inappropriate medications and factors influencing

Full Text available with Trip Pro

2015 Drugs - real world outcomes

297. Behavioral and Psychological Symptoms of Dementia and Antipsychotic Drug Use in the Elderly with Dementia in Korean Long-Term Care Facilities (PubMed)

Behavioral and Psychological Symptoms of Dementia and Antipsychotic Drug Use in the Elderly with Dementia in Korean Long-Term Care Facilities Behavioral and psychological symptoms of dementia (BPSD) are known predictors of institutionalization, lower quality of life, and caregiver distress. Guidelines recommend initial management with non-pharmacological means, but antipsychotic drugs are widely used for the treatment of certain BPSD.The objective of the current study is to analyze

Full Text available with Trip Pro

2015 Drugs - real world outcomes

298. Post-Operative Anticoagulation of Elderly Surgical Patients with Impaired Renal Function: Clinical Effectiveness and Guidelines

Post-Operative Anticoagulation of Elderly Surgical Patients with Impaired Renal Function: Clinical Effectiveness and Guidelines Post-Operative Anticoagulation of Elderly Surgical Patients with Impaired Renal Function: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Post-Operative Anticoagulation of Elderly Surgical Patients with Impaired Renal Function: Clinical Effectiveness and Guidelines Post-Operative Anticoagulation of Elderly Surgical Patients with Impaired (...) Renal Function: Clinical Effectiveness and Guidelines Published on: November 9, 2015 Project Number: RA0816-000 Product Line: Research Type: Drug Report Type: Reference List Result type: Report Question What is the comparative clinical effectiveness of various low weight molecular heparins for post-operative anticoagulation of elderly (aged 65 years) surgical patients with impaired renal function? What is the comparative clinical effectiveness of unfractionated heparin versus low weight molecular

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

299. Development and implementation of Persian test of Elderly for Assessment of Cognition and Executive function (PEACE) (PubMed)

Development and implementation of Persian test of Elderly for Assessment of Cognition and Executive function (PEACE) A considerable segment of the elderly population in Iran is illiterate, and it seems the existing neuropsychological screening tests are not very useful for detecting dementia in illiterate participants. The purpose of this study was to develop and validate a tool called Persian test of Elderly for Assessment of Cognition and Executive function (PEACE) for detecting dementia

Full Text available with Trip Pro

2015 Electronic physician

300. Efficacy of Low-Dose Oral Liquid Morphine for Elderly Patients with Chronic Non-Cancer Pain: Retrospective Chart Review (PubMed)

Efficacy of Low-Dose Oral Liquid Morphine for Elderly Patients with Chronic Non-Cancer Pain: Retrospective Chart Review The use of medications among older persons can often be challenging as physiological changes may affect metabolism and cognitive abilities. Several studies show that the elderly with chronic pain are seriously undertreated or inappropriately treated, particularly with respect to opioids.To determine whether very low doses of oral liquid morphine (LM) in patients over 65 years (...) ratio was 4:1, mean age 75.5 years and mean pain duration 7.9 years. The initial dose of LM for all patients was 1-3 mg three times/day and the maintenance dose ranged from 5 to 30 mg/day. Overall, pain ratings dropped from 6.35 to 2.95 (3.4 point drop on the NRS score) with a mean follow-up of 14 months (range 10-21).The case series showed that carefully selected elderly patients with biomedical pathology can benefit from very low doses of LM. Future larger and well-designed studies need to focus

Full Text available with Trip Pro

2015 Drugs - real world outcomes