Latest & greatest articles for elderly

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Top results for elderly

261. Low performance of bleeding risk models in the very elderly with atrial fibrillation using vitamin K antagonists (Full text)

Low performance of bleeding risk models in the very elderly with atrial fibrillation using vitamin K antagonists Essentials Under-treatment of oral anticoagulation in the elderly with atrial fibrillation is common. As bleeding prediction is challenging, we compared HAS-BLED, ATRIA and HEMORR2 HAGES. All three were associated with major bleeding in the elderly, but with poor predictive abilities. Future studies with focus on elderly-specific risk factors for bleeding are warranted.Background (...) Anticipated bleeding complications contribute to underuse of oral anticoagulants, especially in elderly patients with atrial fibrillation (AF). Bleeding risk models could provide guidance; however, these were developed in the general AF population. Objective To study and compare the performance of the HAS-BLED, ATRIA and HEMORR2 HAGES for major bleeding in very elderly AF patients. Methods Subjects were a random sample (N = 1157) of AF patients ≥ 80 years using a vitamin-K antagonist with prospective

2016 EvidenceUpdates PubMed

262. Development of a decision guide to support the elderly in decision making about location of care: an iterative, user-centered design (Full text)

Development of a decision guide to support the elderly in decision making about location of care: an iterative, user-centered design For the elderly to get the care and services they need, they may need to make the difficult decision about staying in their home or moving to another home. Many other people may be involved in their care too (friends, family and healthcare providers), and can support them in making the decision. We asked informal caregivers of elderly people to help us develop (...) a decision guide to support them and their loved ones in making this decision. This guide will be used by health providers in home care who are trained to help people make decisions. The guide is in French and English. To design and test this decision guide we involved elderly people, their caregivers and health administrators. We first asked them what they needed for making the decision, and then designed a first version of the guide. Then we asked them to look at it and give feedback, which was used

2016 Research involvement and engagement PubMed

263. Chemoradiation therapy with docetaxel in elderly patients with stage II/III esophageal cancer: A phase 2 trial (Full text)

Chemoradiation therapy with docetaxel in elderly patients with stage II/III esophageal cancer: A phase 2 trial The most effective treatments in elderly patients with esophageal cancer remain a subject of debate. This multicenter phase 2 study was designed to evaluate the efficacy and toxicity of chemoradiation therapy (CRT) with docetaxel (DTX) in elderly patients with stage II/III (non-T4) esophageal cancer.Patients ≥70 years of age with clinical stage II/III esophageal cancer received DTX (...) %), thrombocytopenia (6.3%), mucositis (6.3%), and infection (6.3%). Grade 3 or higher late toxicities included esophagitis (12.5%), pleural effusion (12.5%), pneumonitis (6.3%), and pericardial effusion (6.3%).CRT with DTX might be a treatment option for elderly patients with stage II/III esophageal cancer, particularly for patients who are medically unfit for surgery or cisplatin-containing therapy. However, further improvements of this therapy are required to decrease the incidence of esophagitis.

2016 Advances in radiation oncology PubMed

264. Long term survival with stereotactic ablative radiotherapy (SABR) versus thoracoscopic sublobar lung resection in elderly people: national population based study with propensity matched comparative analysis. (Full text)

Long term survival with stereotactic ablative radiotherapy (SABR) versus thoracoscopic sublobar lung resection in elderly people: national population based study with propensity matched comparative analysis.  To compare cancer specific survival after thoracoscopic sublobar lung resection and stereotactic ablative radiotherapy (SABR) for tumors ≤2 cm in size and thoracoscopic resection (sublobar resection or lobectomy) and SABR for tumors ≤5 cm in size. National population based retrospective

2016 BMJ PubMed

265. CPX-351 (VYXEOS) for elderly patients with newly diagnosed acute myeloid leukaemia - first line

CPX-351 (VYXEOS) for elderly patients with newly diagnosed acute myeloid leukaemia - first line CPX-351 (VYXEOS) for elderly patients with newly diagnosed acute myeloid leukaemia – first line CPX-351 (VYXEOS) for elderly patients with newly diagnosed acute myeloid leukaemia – first line NIHR HSRIC Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation NIHR HSRIC. CPX (...) -351 (VYXEOS) for elderly patients with newly diagnosed acute myeloid leukaemia – first line. Birmingham: NIHR Horizon Scanning Research&Intelligence Centre. Horizon Scanning Review. 2016 Authors' conclusions Acute myeloid leukaemia is a rare type of cancer that affects the way blood cells are developed so that they do not work properly. This leads to an increased risk of infection, as well as symptoms such as anaemia and bruising. It can affect people at any age but is more common in people over

2016 Health Technology Assessment (HTA) Database.

266. CETORNAN 5 g (ornithine), treatment of liver disease - elderly undernourished subjects

CETORNAN 5 g (ornithine), treatment of liver disease - elderly undernourished subjects CETORNAN SUMMARY CT14506

2016 Haute Autorite de sante

267. Burden and associated factors for caregivers of the elderly in a developing country

Burden and associated factors for caregivers of the elderly in a developing country Burden and associated factors for caregivers of the elderly in a developing country JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links Burden and associated factors for caregivers of the elderly in a developing country View/ Open View Statistics Altmetrics Share Abstract The elderly population (...) in South Asia is growing. In Pakistan trained caregivers are scarce and culturally not acceptable. This study assessed the level of stress experienced by caregivers of the elderly and determined the association of care giving burden with different characteristics of the elderly. A cross-sectional, questionnaire based study was conducted using nonprobability purposive sampling. All consenting participants aged 60 years and above needing help with at least one activity of daily living or two instrumental

2016 WHO

268. Polytrauma in the elderly: a review (Full text)

Polytrauma in the elderly: a review Although the field of geriatric trauma is - ironically - young, care for the elderly trauma patient is increasingly recognised as an important challenge, considering the worldwide trend towards increasing longevity.Increasing age is associated with physiological changes and resulting comorbidities that present multiple challenges to the treating physician.Even though polytrauma is less likely with increasing age, lower-energy trauma can also result in life (...) -threatening injuries due to the reduced physiological reserve.Mechanisms of injury and resulting injury patterns are markedly changed in the elderly population and new management strategies are needed. From initial triage to long-term rehabilitation, these patients require care that differs from the everyday standard.In the current review, the special requirements of this increasing patient population are reviewed and management options discussed. With the increase in orthogeriatrics as a speciality

2016 EFORT open reviews PubMed

269. Management of ankle fractures in the elderly (Full text)

Management of ankle fractures in the elderly The incidence and severity of ankle fractures in elderly patients is increasing steadily. These injuries are challenging to treat and prone to complications.Individual fracture treatment is tailored depending on bone quality, skin conditions, comorbidities, and functional demand of the patient. This article provides a review of current techniques to obtain stable fixation despite poor bone quality. To avoid complications, it is imperative to consider (...) and treat comorbidities such as diabetes and osteoporosis.In the absence of severe systemic comorbidities, the results after open reduction and internal fixation of malleolar fractures in patients above and below 60 years of age are nearly identical, while nonoperative treatment of unstable fractures leads to significantly inferior outcomes. Therefore, the general indications for surgery in elderly patients should not differ from those in younger patients.However, it is essential to detect severe

2016 EFORT open reviews PubMed

270. Evaluating physical function and activity in the elderly patient using wearable motion sensors (Full text)

Evaluating physical function and activity in the elderly patient using wearable motion sensors Wearable sensors, in particular inertial measurement units (IMUs) allow the objective, valid, discriminative and responsive assessment of physical function during functional tests such as gait, stair climbing or sit-to-stand.Applied to various body segments, precise capture of time-to-task achievement, spatiotemporal gait and kinematic parameters of demanding tests or specific to an affected limb (...) are the most used measures.In activity monitoring (AM), accelerometry has mainly been used to derive energy expenditure or general health related parameters such as total step counts.In orthopaedics and the elderly, counting specific events such as stairs or high intensity activities were clinimetrically most powerful; as were qualitative parameters at the 'micro-level' of activity such as step frequency or sit-stand duration.Low cost and ease of use allow routine clinical application but with many options

2016 EFORT open reviews PubMed

271. Impact of falling on social participation and social support trajectories in a middle-aged and elderly European sample (Full text)

Impact of falling on social participation and social support trajectories in a middle-aged and elderly European sample Whereas falls are frequent and traumatic events for the elderly, their long-term consequences in terms of the social lives of older fallers are understudied. This study aimed to identify the impact of falling on the trajectories of social participation and social support of older people in Europe. Our sample consisted of 16,583 people aged 50-95 years from 10 European countries

2016 SSM - population health PubMed

272. Persistence of Antipsychotic Treatment in Elderly Dementia Patients: A Retrospective, Population-Based Cohort Study (Full text)

Persistence of Antipsychotic Treatment in Elderly Dementia Patients: A Retrospective, Population-Based Cohort Study Antipsychotics are commonly used to manage behavioral and psychological symptoms of dementia. Concerns over their safety and efficacy in this role have resulted in antipsychotics typically being recommended for short-term usage only when used among dementia patients. However, there is little work examining the duration of antipsychotic treatment in the elderly dementia patient (...) population.To determine the persistence of use of antipsychotics in elderly dementia patients and the role of dose on therapy duration.A retrospective, population-based cohort study using administrative data, including dispensing records from a provincial public drug program, from Ontario, Canada between 2009 and 2012. Elderly dementia patients newly initiated onto antipsychotics were followed until drug discontinuation, death, 2-year follow-up, or end of study. Competing risk analysis was performed

2016 Drugs - real world outcomes PubMed

273. Effect of Structured Physical Activity on Respiratory Outcomes in Sedentary Elderly Adults with Mobility Limitations (Full text)

Effect of Structured Physical Activity on Respiratory Outcomes in Sedentary Elderly Adults with Mobility Limitations To evaluate the effect of structured physical activity on respiratory outcomes in community-dwelling elderly adults with mobility limitations.Multicenter, randomized trial of physical activity vs health education, with respiratory variables prespecified as tertiary outcomes over an intervention period of 24-42 months. Physical activity included walking (goal of 150 min/week

2016 EvidenceUpdates PubMed

274. An elderly with a ‘bony’ smile (Full text)

An elderly with a ‘bony’ smile 28461848 2018 11 13 1985-207X 11 1 2016 Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia Malays Fam Physician An elderly with a 'bony' smile. 31-32 Mohamad I I M.D, M.Med (ORL-HNS) Department of Otorhinolaryngology Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kota Bharu, Kelantan, Malaysia. Email: irfankb@usm.my. Nadarajah S S M.D, FRCS (C) Department

2016 Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia PubMed

275. Prevalence of falls among community-dwelling elderly and its associated factors: A cross-sectional study in Perak, Malaysia (Full text)

Prevalence of falls among community-dwelling elderly and its associated factors: A cross-sectional study in Perak, Malaysia Fall is a major cause of injuries and can increase the risk of early mortality among elderly. The objective of this study was to determine the prevalence of falls among community-dwelling elderly in rural Malaysia and its associated factors.Data were obtained from a cross-sectional survey in five randomly selected districts in the state of Perak, Malaysia. A total of 250 (...) households were randomly selected. A total of 811 individuals aged 60 years or more were recruited and interviewed using a structured questionnaire. Information about socio-demographic, history of falls in the past 1 year, medical history, drug history and physical activity level were enquired.The prevalence of falls in the past 1 year among community-dwelling elderly was reported to be 4.07%. Indigenous elderly (Adjusted odd ratio, AOR = 6.06, 95% CI = 1.10-33.55, p = 0.039) and living alone (AOR = 2.60

2016 Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia PubMed

276. Challenge of cancer in the elderly (Full text)

Challenge of cancer in the elderly Despite the sustained trend of decreasing overall cancer incidence, the number of elderly patients with cancer will considerably increase in the coming years, as the incidence of cancer is elevated 11-fold after the age of 65 years compared to adults up to 65 years. This soon-to-erupt tsunami of elderly patients with cancer requires adequate treatment, for which guidelines and evidence-based data are still scarce, given the longlasting under-representation (...) of elderly patients with cancer in cancer trials. Older adults present not only with the physiological decreases of organ functions related to age, but also with an individual burden of comorbidities, other impairments and social factors that might impact on their potential for undergoing cancer care. Close collaboration with gerontologists and other health professionals to assess the personal resources and limitations of each person enables providing adequate therapy to elderly patients with cancer

2016 ESMO open PubMed

277. Erratum to: Haloperidol Use Among Elderly Patients Undergoing Surgery: A Retrospective 1-Year Study in a Hospital Population (Full text)

Erratum to: Haloperidol Use Among Elderly Patients Undergoing Surgery: A Retrospective 1-Year Study in a Hospital Population 27747622 2017 08 16 2199-1154 3 2 2016 Jun Drugs - real world outcomes Drugs Real World Outcomes Erratum to: Haloperidol Use Among Elderly Patients Undergoing Surgery: A Retrospective 1-Year Study in a Hospital Population. 239 Nijboer Harmke H Catharina Hospital, Eindhoven, Brabant, The Netherlands. harmke.nijboer@catharinaziekenhuis.nl. Lefeber Geert G Catharina Hospital

2016 Drugs - real world outcomes PubMed

278. Triplet vs doublet lenalidomide-containing regimens for the treatment of elderly patients with newly diagnosed multiple myeloma (Full text)

Triplet vs doublet lenalidomide-containing regimens for the treatment of elderly patients with newly diagnosed multiple myeloma Lenalidomide-dexamethasone improved outcome in newly diagnosed elderly multiple myeloma patients. We randomly assigned 662 patients who were age ≥65 years or transplantation-ineligible to receive induction with melphalan-prednisone-lenalidomide (MPR) or cyclophosphamide-prednisone-lenalidomide (CPR) or lenalidomide plus low-dose dexamethasone (Rd). The primary end

2016 EvidenceUpdates PubMed

279. Pain Management for Women, Aboriginal Peoples, or the Elderly: Guidelines

Pain Management for Women, Aboriginal Peoples, or the Elderly: Guidelines Pain Management for Women, Aboriginal Peoples, or the Elderly: Guidelines | CADTH.ca Find the information you need Pain Management for Women, Aboriginal Peoples, or the Elderly: Guidelines Pain Management for Women, Aboriginal Peoples, or the Elderly: Guidelines Published on: March 28, 2016 Project Number: RB0975-000 Product Line: Research Type: Drug Report Type: Summary of Abstracts Result type: Report Question What (...) are the evidence-based guidelines for pain management in women with chronic non-cancer pain? What are the evidence-based guidelines for pain management in Aboriginal peoples with chronic non-cancer pain? What are the evidence-based guidelines for pain management in the elderly population with chronic non-cancer pain? Key Message One evidence-based guideline was identified regarding pain management for the elderly. Tags aged, chronic pain, geriatrics, health services, inuits, pain management, women, long-term

2016 Canadian Agency for Drugs and Technologies in Health - Rapid Review

280. Drug-Related Problems Identified in a Sample of Portuguese Institutionalised Elderly Patients and Pharmacists’ Interventions to Improve Safety and Effectiveness of Medicines (Full text)

Drug-Related Problems Identified in a Sample of Portuguese Institutionalised Elderly Patients and Pharmacists’ Interventions to Improve Safety and Effectiveness of Medicines Currently, people live longer but often with poor quality of life. The decrease in healthy life-years is partly attributable to the institution of polypharmacy to treat various comorbidities.The objectives of the study were to determine the prevalence and nature of drug-related problems (DRPs) in polypharmacy elderly (...) patients residing in nursing homes and to test the acceptability of a pharmacist's intervention.An exposure cohort was constituted in three Portuguese nursing homes, where all polypharmacy (five or more medicines) elderly patients (≥65 years of age) were analysed and then a random stratified sample was extracted to be subject to an intervention. Clinical and therapeutic data were collected and analysed for DRPs and classified according to the II Granada Consensus, by a pharmacist-led team

2016 Drugs - real world outcomes PubMed