Latest & greatest articles for elderly

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Top results for elderly

241. The effect of group exercises on balance, mobility, and depressive symptoms in older adults with mild cognitive impairment: a randomized controlled trial (Abstract)

The effect of group exercises on balance, mobility, and depressive symptoms in older adults with mild cognitive impairment: a randomized controlled trial To determine the effects of group exercises on balance, mobility, and depressive symptoms in community-dwelling older adults with mild cognitive impairment.Single blinded, randomized, matched pairs clinical trial.Four primary healthcare units.Fifty-two sedentary subjects with mild cognitive impairment were paired (age, sex, body mass index (...) , and Addenbrooke's Cognitive Examination Revised score), tested, and then randomized into an intervention group ( n = 26) and a control group ( n = 26).The intervention group performed strength (ankle weights, elastic bands, and dumbbells) and aerobic exercises (walking) in their communities' public spaces, twice a week (60 minutes each), during 24 weeks. The control group maintained its usual routine.Balance (Berg Balance Scale (BBS)), mobility (Timed Up and Go Test (TUG)), and depressive symptoms (Geriatric

2019 EvidenceUpdates

242. Lifestyle and neurocognition in older adults with cognitive impairments: A randomized trial Full Text available with Trip Pro

Lifestyle and neurocognition in older adults with cognitive impairments: A randomized trial To determine the independent and additive effects of aerobic exercise (AE) and the Dietary Approaches to Stop Hypertension (DASH) diet on executive functioning in adults with cognitive impairments with no dementia (CIND) and risk factors for cardiovascular disease (CVD).A 2-by-2 factorial (exercise/no exercise and DASH diet/no DASH diet) randomized clinical trial was conducted in 160 sedentary men (...) and women (age >55 years) with CIND and CVD risk factors. Participants were randomly assigned to 6 months of AE, DASH diet nutritional counseling, a combination of both AE and DASH, or health education (HE). The primary endpoint was a prespecified composite measure of executive function; secondary outcomes included measures of language/verbal fluency, memory, and ratings on the modified Clinical Dementia Rating Scale.Participants who engaged in AE (d = 0.32, p = 0.046) but not those who consumed

2019 EvidenceUpdates

243. Placebo vs Amoxicillin for Nonsevere Fast-Breathing Pneumonia in Malawian Children Aged 2 to 59 Months: A Double-blind, Randomized Clinical Noninferiority Trial Full Text available with Trip Pro

Placebo vs Amoxicillin for Nonsevere Fast-Breathing Pneumonia in Malawian Children Aged 2 to 59 Months: A Double-blind, Randomized Clinical Noninferiority Trial Pneumonia is the leading infectious killer of children. Rigorous evidence supporting antibiotic treatment of children with nonsevere fast-breathing pneumonia in low-resource African settings is lacking.To assess whether treatment with placebo for nonsevere fast-breathing pneumonia is substantively less effective than 3 days of treatment (...) with amoxicillin.This double-blind, 2-arm, randomized clinical noninferiority trial with follow-up of 14 days screened 1343 HIV-uninfected children aged 2 to 59 months with nonsevere fast-breathing pneumonia at outpatient departments of hospitals in Lilongwe, Malawi, Africa, between June 2016 and June 2017.Placebo or amoxicillin dispersible tablets administered twice daily for 3 days.The primary end point was the proportion of children failing treatment by day 4 with a relative noninferiority margin of 1.5 times

2019 EvidenceUpdates

244. Effect of Age on Opioid Prescribing, Overdose, and Mortality in Massachusetts, 2011 to 2015 Full Text available with Trip Pro

: high-dose opioids, coprescription with benzodiazepines, multiple opioid prescribers, multiple opioid pharmacies, and continuous opioid therapy without a pain diagnosis. We examined 3 adverse outcomes: nonfatal opioid overdose, fatal opioid overdose, and all-cause mortality.The rate of any PIP increased with age, from 2% of individuals age 18 to 29 to 14% of those aged 50 and older. Older adults also had higher rates of exposure to 2 or more different types of PIP (40-49, 2.5%; 50-69, 5%; ≥70, 4 (...) %). Of covariates assessed, older age was the greatest predictor of PIP. In analyses stratified according to age, any PIP and specific types of PIP were associated with nonfatal overdose, fatal overdose, and all-cause mortality in younger and older adults.Older adults are more likely to be exposed to PIP, which increases their risk of adverse events. Strategies to reduce exposure to PIP and to improve outcomes in those already exposed will be instrumental to addressing the opioid crisis in older adults. J Am

2019 EvidenceUpdates

245. Dialysis Modality and Incident Atrial Fibrillation in Older Patients With ESRD Full Text available with Trip Pro

Dialysis Modality and Incident Atrial Fibrillation in Older Patients With ESRD Atrial fibrillation (AF) is common in patients with kidney failure treated by maintenance dialysis. Whether the incidence of AF differs between patients receiving hemodialysis and peritoneal dialysis is uncertain.Retrospective cohort study.Using the US Renal Data System, we identified older patients (≥67 years) with Medicare Parts A and B who initiated dialysis therapy (1996-2011) without a diagnosis of AF during (...) the prior 2 years.Dialysis modality at incident end-stage renal disease (ESRD) and maintained for at least 90 days.Patients were followed up for 36 months or less for a new diagnosis of AF.Time-to-event analysis using multivariable Cox proportional hazards regression to estimate cause-specific HRs while censoring at modality switch, kidney transplantation, or death.Overall, 271,722 older patients were eligible; 17,487 (6.9%) were treated with peritoneal dialysis, and 254,235 (93.1%), with hemodialysis

2019 EvidenceUpdates

246. Comparative risk of harm associated with trazodone or atypical antipsychotic use in older adults with dementia: a retrospective cohort study Full Text available with Trip Pro

with chronic psychotic illnesses) living in long-term care and aged 66 years and older. Data were obtained from routinely collected, linked health administrative databases in Ontario, Canada. We compared new users of trazodone with new users of atypical antipsychotics (quetiapine, olanzapine or risperidone) between Dec. 1, 2009, and Dec. 31, 2015. The primary outcome was a composite of fall or major osteoporotic fracture within 90 days of first prescription. Secondary outcomes were falls, major (...) Comparative risk of harm associated with trazodone or atypical antipsychotic use in older adults with dementia: a retrospective cohort study Trazodone is increasingly prescribed for behavioural and psychological symptoms of dementia, but little is known about its risk of harm. Our objective was to describe the comparative risk of falls and fractures among older adults with dementia dispensed trazodone or atypical antipsychotics.The study cohort included adults with dementia (excluding patients

2019 EvidenceUpdates

247. Assessing Risk for Adverse Outcomes in Older Adults: The Need to Include Both Physical Frailty and Cognition Full Text available with Trip Pro

activities of daily living (ADL) dependence and death over 8 years.Prospective cohort study.The Health and Retirement Study (HRS).A total of 7338 community-dwelling people, 65 years or older, without dementia and ADL dependence at baseline (2006-2008). Follow-up assessments occurred every 2 years until 2014.The five components of the Cardiovascular Health Study defined physical frailty. A well-validated HRS method, including verbal recall, series of subtractions, and backward count task, assessed (...) of ADL dependence (Harrell's concordance [C], 0.74 vs 0.71; P < .001) and death (Harrell's C, 0.70 vs 0.67; P < .001).Physical frailty and CIND are independent predictors of incident disability and death. Because together physical frailty and CIND identify vulnerable older adults better, optimal risk assessment should supplement measures of physical frailty with measures of cognitive function. J Am Geriatr Soc 67:477-483, 2019.© 2018 The American Geriatrics Society.

2019 EvidenceUpdates

248. Prospective Validation of a Checklist to Predict Short-term Death in Older Patients After Emergency Department Admission in Australia and Ireland Full Text available with Trip Pro

Prospective Validation of a Checklist to Predict Short-term Death in Older Patients After Emergency Department Admission in Australia and Ireland Emergency departments (EDs) are pressured environment where patients with supportive and palliative care needs may not be identified. We aimed to test the predictive ability of the CriSTAL (Criteria for Screening and Triaging to Appropriate aLternative care) checklist to flag patients at risk of death within 3 months who may benefit from timely end (...) -of-life discussions.Prospective cohorts of >65-year-old patients admitted for at least one night via EDs in five Australian hospitals and one Irish hospital. Purpose-trained nurses and medical students screened for frailty using two instruments concurrently and completed the other risk factors on the CriSTAL tool at admission. Postdischarge telephone follow-up was used to determine survival status. Logistic regression and bootstrapping techniques were used to test the predictive accuracy of CriSTAL

2019 EvidenceUpdates

249. Association of age at first severe RSV disease with subsequent risk of severe asthma: a population-based cohort study Full Text available with Trip Pro

Association of age at first severe RSV disease with subsequent risk of severe asthma: a population-based cohort study In a population-based cohort study, we determined the association between the age at first severe respiratory syncytial virus (RSV) disease and subsequent asthma.Incidence rates and rate ratios of the first asthma-associated hospitalization after 2 years of age in children hospitalized for RSV disease at <3 months, 3 to <6 months, 6 to <12 months, and 12-24 months of age were (...) calculated.The incidence of asthma-associated hospitalization per 1000 child-years among children hospitalized for RSV disease at <3 months of age was 0.5 (95% confidence interval [CI], .2-.7); at 3 to <6 months of age, 0.9 (95% CI,.5-1.3); at 6 to <12 months of age, 2.0 (95% CI, 1.4-2.7); and at 12-24 months of age, 1.7 (95% CI, 1.0-2.5). The rate ratio of hospitalization for asthma was 2-7-fold greater among children hospitalized for RSV disease at ages ≥6 months than that among those hospitalized for RSV

2019 EvidenceUpdates

250. Randomized Clinical Trial of Intravenous Acetaminophen as an Analgesic Adjunct for Older Adults With Acute Severe Pain (Abstract)

Randomized Clinical Trial of Intravenous Acetaminophen as an Analgesic Adjunct for Older Adults With Acute Severe Pain Older adults are at risk for undertreatment of pain. We examined intravenous (IV) acetaminophen as an analgesic adjunct to IV opioids in the care of older emergency department (ED) patients with acute severe pain.This was a randomized clinical trial conducted in two EDs in the Bronx, New York. Eligible adults aged 65 years and older with acute severe pain were randomized to 0.5 (...) in the hydromorphone + IV acetaminophen group wanted more analgesia at 60 minutes versus 29.1% in the hydromorphone + placebo group, for a difference of -0.4% (95% CI = -14.3% to 13.5%). These differences were neither clinically nor statistically significant. Safety profiles were similar in both groups.In this randomized clinical trial, the addition of IV acetaminophen to IV hydromorphone as an adjunctive analgesic for acute, severe, pain in older adults provided neither clinically nor statistically superior pain

2019 EvidenceUpdates

251. Effect of Hospitalizations on Physical Activity Patterns in Mobility-Limited Older Adults Full Text available with Trip Pro

Effect of Hospitalizations on Physical Activity Patterns in Mobility-Limited Older Adults To evaluate the effect of hospitalizations on patterns of sedentary and physical activity time in mobility-limited older adults randomized to structured physical activity or health education.Secondary analysis of investigator-blinded, parallel-group, randomized trial conducted at 8 U.S. centers between February 2010 and December 2013.Sedentary men and women aged 70 to 89 at baseline who wore a hip-fitted (...) accelerometer 7 consecutive days at baseline and 6, 12, and 24 months after randomization (N=1,341).Participants were randomized to a physical activity (PA; n = 669) intervention that included aerobic, resistance, and flexibility training or to a health education (HE; n = 672) intervention that consisted of workshops on older adult health and light upper-extremity stretching. Accelerometer patterns were characterized as bouts of sedentary (<100 counts/min; ≥1, ≥10, ≥30, ≥60 minute lengths) and activity

2019 EvidenceUpdates

252. Women’s health and midwifery: Risky maternal alcohol consumption during lactation decreases childhood abstract reasoning at school age

Women’s health and midwifery: Risky maternal alcohol consumption during lactation decreases childhood abstract reasoning at school age Risky maternal alcohol consumption during lactation decreases childhood abstract reasoning at school age | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Risky maternal alcohol consumption during lactation decreases childhood abstract reasoning at school age Article Text Commentary Women’s health

2019 Evidence-Based Nursing

253. Care of the older person: Evaluating falls prevention strategies in community settings: marginal reduction on rate of falls with individual risk-based multifactorial interventions compared to ‘usual care’

, et al. (2018) Multifactorial and multiple component interventions for preventing falls in older people living in the community. London: John Wiley & Sons. Implications for practice and research Multifactorial interventions may reduce fall rates in older people, whereas multiple component interventions may reduce risk of and rates of falls.However, evidence is low quality, so findings have limited implications to practice. Further research is required to determine the effectiveness of more (...) specific intervention strategies, particularly those related to exercise and adherence to interventional regimes. Context Falls are common in older populations and levels of frailty, increasing age, impairment of functional status (cognitive/physiological), reduced mobility and environmental factors increase risk. 1 Identification and reduction of modifiable … Footnotes Competing interests None declared. Provenance and peer review Commissioned; internally peer reviewed. Request Permissions If you wish

2019 Evidence-Based Nursing

254. Effect on falls among elderly persons after training elderly care staff

Effect on falls among elderly persons after training elderly care staff Effect on falls among elderly persons after training elderly care staff We use cookies on this website. By using this site, you agree that we may store and access cookies on your device. Swedish Agency for Health Technology Assessment and Assessment of Social Services Effect on falls among elderly persons after training elderly care staff Share: Reading time approx. 4 minutes In general, every person aged 65 years or older (...) received our training after the study was completed. Resident falls and cognition. Authors' conclusion: “Relatively light educational intervention with activating learning methods may improve nursing staff’s knowledge of older people’s harmful medications. It is possible to reduce number of falls among older people in institutional settings by reducing their use of harmful medication”. References Balzer K, Bremer M, Schramm S, Luhmann D, Raspe H. Falls prevention for the elderly. GMS Health Technol

2019 Swedish Council on Technology Assessement

255. Care of the older person: Better support and education is imperative to bolster informal at-home carers of people with cognitive impairment and reduce incidences of involuntary treatment of older adults in their homes

Care of the older person: Better support and education is imperative to bolster informal at-home carers of people with cognitive impairment and reduce incidences of involuntary treatment of older adults in their homes Better support and education is imperative to bolster informal at-home carers of people with cognitive impairment and reduce incidences of involuntary treatment of older adults in their homes | Evidence-Based Nursing Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Better support and education is imperative to bolster informal at-home carers of people with cognitive impairment and reduce incidences of involuntary treatment of older adults in their homes Article

2019 Evidence-Based Nursing

256. Care of the older person: Evidence that active pain treatment improves sleep quality and quantity in people with depression and dementia Full Text available with Trip Pro

Care of the older person: Evidence that active pain treatment improves sleep quality and quantity in people with depression and dementia Evidence that active pain treatment improves sleep quality and quantity in people with depression and dementia | Evidence-Based Nursing Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Evidence that active pain treatment improves sleep quality and quantity in people with depression and dementia Article Text Commentary Care of the older person Evidence that active pain treatment improves sleep quality and quantity in people with depression and dementia Amelia Swift Statistics from Altmetric.com Commentary on : Blytt KM, Bjorvatn B, Husebo B

2019 Evidence-Based Nursing

257. FDA Approval of 9-valent HPV Vaccine for Use in Women and Men Age 27-45

FDA Approval of 9-valent HPV Vaccine for Use in Women and Men Age 27-45 FDA Approval of 9-valent HPV Vaccine for Use in Women and Men Age 27-45 | ACOG Clinical Guidance Journals & Publications Patient Education Topics Featured Clinical Topics Hi, Featured Clinical Topics Clinical Guidance FDA Approval of 9-valent HPV Vaccine for Use in Women and Men Age 27-45 Practice Advisory June 2019 Jump to Resources Share By reading this page you agree to ACOG's Terms and Conditions. . The Centers (...) for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP) reviewed the available data at its February 2019 and June 2019 in-person meetings. On June 26, 2019, ACIP voted to recommend shared clinical decision making for persons aged 27 through 45 years when considering the 9-valent HPV vaccine. This recommendation is for women who have not previously received an HPV vaccine series and who are at risk for acquisition of HPV. HPV vaccination is most effective when given during

2019 American College of Obstetricians and Gynecologists

258. Management of Pregnant and Reproductive Aged Women during a Measles Outbreak

Management of Pregnant and Reproductive Aged Women during a Measles Outbreak Management of Pregnant and Reproductive Aged Women during a Measles Outbreak | ACOG Clinical Guidance Journals & Publications Patient Education Topics Featured Clinical Topics Hi, Featured Clinical Topics Clinical Guidance Management of Pregnant and Reproductive Aged Women during a Measles Outbreak Practice Advisory April 2019 Jump to Resources Share By reading this page you agree to ACOG's Terms and Conditions (...) in a community must be immune to prevent ongoing transmission. Measles can cause serious illness and infects approximately nine out of every ten susceptible individuals exposed in close-contact settings . Anyone who is unvaccinated or is undervaccinated is at risk. Certain individuals, including unvaccinated and undervaccinated pregnant women, infants 12 months of age or younger, and severely immunocompromised persons are at increased risk of severe illness and complications of measles . The two-dose series

2019 American College of Obstetricians and Gynecologists

259. Ivacaftor (cystic fibrosis, 2 years and older, with gating mutations) - Benefit assessment according to §35a Social Code Book V

(hereinafter referred to as “the company”). The dossier was sent to IQWiG on 28 August 2019. Research question The aim of the present report is the assessment of the added benefit of ivacaftor in comparison with the appropriate comparator therapy (ACT) best supportive care (BSC) in patients with cystic fibrosis (CF) aged 2 years and older and weighing between 7 kg and less than 25 kg who have one of the following gating (class III) mutations in the cystic fibrosis transmembrane conductance regulator (CFTR (...) ) gene: G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N or S549R. Table 2: Research questions of the benefit assessment of ivacaftor Subindication ACT a Patients with cystic fibrosis aged 2 years and older and weighing between 7 kg and less than 25 kg who have one of the following gating (class III) mutations in the CFTR gene: G551D, G551S, G1244E, G1349D, G178R, S1251N, S1255P, S549N or S549R BSC b a: Presentation of the ACT specified by the G-BA. b: BSC refers to the therapy

2019 Institute for Quality and Efficiency in Healthcare (IQWiG)

260. Ivacaftor (cystic fibrosis, 18 years and older, with R117H mutation) - Benefit assessment according to §35a Social Code Book V

of the added benefit of ivacaftor in comparison with the appropriate comparator therapy (ACT) best supportive care (BSC) in the treatment of patients with cystic fibrosis (CF) aged 18 years and older who have an R117H mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Table 2: Research question of the benefit assessment of ivacaftor Subindication ACT a Patients with cystic fibrosis aged 18 years and older who have an R117H mutation in the CFTR gene BSC a: Presentation (...) a Probability and extent of added benefit Patients with cystic fibrosis aged 18 years and older who have an R117H mutation in the CFTR gene BSC Hint of a non-quantifiable added benefit a: Presentation of the ACT specified by the G-BA. ACT: appropriate comparator therapy; BSC: best supportive care; CFTR: cystic fibrosis transmembrane conductance regulator; G-BA: Federal Joint Committee The approach for deriving an overall conclusion on the added benefit is a proposal by IQWiG. The G-BA decides on the added

2019 Institute for Quality and Efficiency in Healthcare (IQWiG)