Latest & greatest articles for elderly

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Top results for elderly

1. Deprescribing for Older Veterans: A Systematic Review

& Development Management eBrief no. 170 » Issue 170 March 2020 The report is a product of the VA/HSR&D Evidence Synthesis Program. Deprescribing for Older Veterans: A Systematic Review More than 40% of people in the United States age ≥65 years take five or more prescription medications on a regular basis to control or prevent disease symptoms and complications. The number of medications a person is taking may be the single most important predictor of adverse drug effects. Efforts have been underway for more (...) medications, and medications known to pose risks in the elderly. The VA Center for Medication Safety in Aging was charged with the development and implementation of deprescribing approaches in VA settings. Commissioned by the National Center for Patient Safety and endorsed by VA Pharmacy Benefits Management and the Geriatrics and Extended Care Services, the purpose of this evidence review is to inform that work. Specific questions to be addressed included: What are the effectiveness, comparative

2020 Veterans Affairs - R&D

2. Preventive home visits to older people

" OR AB "Health promotion") 1236 4. 1 OR 2 OR 3 5690 Population: 5. DE "OLDER people" 7927 6. (TI (elderly OR aged OR old*) N2 (person* OR people* OR m#n OR wom#n OR patient*)) OR (AB (elderly OR aged OR old*) N2 (person* OR people* OR m#n OR wom#n OR patient*)) 29086 7. (TI (geriatric* OR "senior citizen*")) OR (AB (geriatric* OR "senior citizen*")) 4799 8. 5 OR 6 OR 7 36564 Study types: 9. DE "Systematic reviews (Medical research)" OR DE "Cochrane reviews" OR DE "Meta-analysis" 5181 10. (TI (...) Population: 5. exp Aged/ 3041480 6. ((elderly or aged or old$) adj2 (person$ or people$ or m?n or wom?n or patient$)).ti,ab. 714320 7. (geriatric$ or senior citizen$).ti,ab 46885 8. 5 OR 6 OR 7 3469976 Study types: 9. Exp systematic review/ OR cochrane library.mp OR exp meta analysis/ 191889 10. ((systematic* ADJ3 review) OR meta analy* OR metaanaly*).ab,ti,kw 255856 11. 9 OR 10 282791 Combined sets: 12. 4 AND 8 5311 Final 11 AND 12 102 Cochrane Library via Wiley 2020-01-14 Preventive home visits

2020 Swedish Council on Technology Assessement

3. Cognitive Impairment in Older Adults: Screening

population: prevalence and associated factors: results of the LIFE-Adult-Study. BMC Psychol . 2018;6:23. 19. Ginó S, Mendes T, Maroco J, et al. Memory complaints are frequent but qualitatively different in young and elderly healthy people. Gerontology . 2010;56(3):272-277. 20. Stites SD, Karlawish J, Harkins K, Rubright JD, Wolk D. Awareness of mild cognitive impairment and mild Alzheimer"s disease dementia diagnoses associated with lower self-ratings of quality of life in older adults. J Gerontol B (...) in the DSM-5 are complex attention, executive function, learning and memory, language, perceptual motor function, and social cognition. Dementia affects an estimated 2.4 to 5.5 million persons in the United States, and its prevalence increases with age. Dementia affects an estimated 3.2% of persons aged 65 to 74 years, 9.9% of those aged 75 to 84 years, and 29.3% of those 85 years or older. Mild cognitive impairment (MCI) differs from dementia in that the impairment is not severe enough to interfere

2020 U.S. Preventive Services Task Force

4. Similar Breast Cancer Risk in Women Older Than 65 Years Initiating Glargine, Detemir, and NPH Insulins

Similar Breast Cancer Risk in Women Older Than 65 Years Initiating Glargine, Detemir, and NPH Insulins Similar Breast Cancer Risk in Women Older Than 65 Years Initiating Glargine, Detemir, and NPH Insulins - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced features are temporarily unavailable. National Institutes (...) to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Diabetes Care Actions 2020 Feb 19 [Online ahead of print] Similar Breast Cancer Risk in Women Older Than 65 Years Initiating Glargine, Detemir, and NPH Insulins , , , , , , , , , , Affiliations Expand Affiliations 1 Office of Surveillance and Epidemiology, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver

2020 EvidenceUpdates

5. A systematic review of the evidence for the efficacy of opioids for chronic non-cancer pain in community-dwelling older adults (Abstract)

A systematic review of the evidence for the efficacy of opioids for chronic non-cancer pain in community-dwelling older adults the ageing global population and concomitant increase in the use of opioid analgesia have highlighted the need to evaluate the effectiveness of opioids for chronic pain in older people.a systematic review of the evidence for the efficacy of opioids for chronic non-cancer pain in community-dwelling people aged 65 years or more was conducted using PRISMA guidelines (...) at baseline was associated with severe pain, severe impairment in activities of daily living and a diagnosis of depression. Fear of causing harm to older people was common amongst opioid prescribers, limiting prescription. Facilitators of opioid prescription included educational interventions and access to an evidence base for opioid use.there is limited evidence supporting the use of long-term opioid use in older people for chronic non-cancer pain and a lack of trials in this age group. Age-specific

2020 EvidenceUpdates

6. Failure of Traditional Risk Factors to Adequately Predict Cardiovascular Events in Older Populations

patients. Among those aged 85 years and older, some traditional risk factors were not associated with ASCVD events. Better risk models are needed to appropriately inform treatment decision making for the growing population of older adults. Keywords: model validation; older adults; risk heterogeneity; risk prediction. © 2020 The American Geriatrics Society. Similar articles MG Nanna et al. J Gen Intern Med. 2019. PMID 31667745. The performance of the PCE for ASCVD risk estimation in older adults (...) to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation J Am Geriatr Soc Actions 2020 Jan 20 [Online ahead of print] Failure of Traditional Risk Factors to Adequately Predict Cardiovascular Events in Older Populations , , , , , Affiliations Expand Affiliations 1 Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, Ohio. 2 Department of Quantitative Health

2020 EvidenceUpdates

7. Comparison of the Effect of Age (< 75 Versus >/= 75) on the Efficacy and Safety of Dual Therapy (Dabigatran+Clopidogrel or Ticagrelor) Versus Triple Therapy (Warfarin+Aspirin+Clopidogrel or Ticagrelor) in Patients With Atrial Fibrillation After Percutaneo Full Text available with Trip Pro

to treatment, 1,026 (37.7%) were categorized into older and 1,699 (62.3%) into younger age groups. Dabigatran 110 mg dual therapy lowered bleeding risk versus warfarin triple therapy in older (hazard ratio [HR] 0.67; 95% confidence interval [CI] 0.51 to 0.89) and younger patients (HR 0.40; 95% CI 0.30 to 0.54); interaction p value: 0.0125. Dabigatran 150 mg dual therapy lowered bleeding risk versus warfarin triple therapy in younger patients (HR 0.57; 95% CI 0.44 to 0.74), whereas no benefit could (...) Comparison of the Effect of Age (< 75 Versus >/= 75) on the Efficacy and Safety of Dual Therapy (Dabigatran+Clopidogrel or Ticagrelor) Versus Triple Therapy (Warfarin+Aspirin+Clopidogrel or Ticagrelor) in Patients With Atrial Fibrillation After Percutaneo Comparison of the Effect of Age ( - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History

2020 EvidenceUpdates

8. Older adults: cost-effective commissioning

and implementing services to support older people's healthy ageing. Published 28 January 2020 From: Documents Ref: PHE publications gateway reference GW-1008 If you use assistive technology (such as a screen reader) and need a version of this document in a more accessible format, please email . Please tell us what format you need. It will help us if you say what assistive technology you use. Ref: PHE publications gateway reference GW-1008 If you use assistive technology (such as a screen reader) and need (...) on identified interventions to support older people, generated through a literature review. The return on investment (ROI) tool: can be adapted to local conditions presents results showing the economic benefits of each intervention has a built-in user guide Local authorities and clinical commissioning groups can use these resources to improve the provision of services for older people. Published 28 January 2020 Related content Explore the topic Is this page useful? Thank you for your feedback Help us

2020 Public Health England

9. Plerixafor (Mozobil) - children aged 1 year to <18 years with lymphoma or solid malignant tumours

Plerixafor (Mozobil) - children aged 1 year to <18 years with lymphoma or solid malignant tumours Published 10 February 2020 1 Product update SMC2249 plerixafor 20mg/mL solution for injection (Mozobil®) Sanofi Aventis 10 January 2020 The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and advises NHS Boards and Area Drug and Therapeutic Committees (ADTCs) on its use in NHSScotland. The advice is summarised as follows: ADVICE: following an abbreviated (...) submission plerixafor (Mozobil®) is accepted for use within NHSScotland. Indication under review: in combination with granulocyte-colony stimulating factor (G-CSF) to enhance mobilisation of haematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in children aged 1 year to <18 years with lymphoma or solid malignant tumours, either: - pre-emptively, when circulating stem cell count on the predicted day of collection after adequate mobilisation with G-CSF

2020 Scottish Medicines Consortium

10. Testosterone Treatment in Adult Men with Age-Related Low Testosterone Full Text available with Trip Pro

, Nankin HR , Spark RF , et al American Association of Clinical Endocrinologists American Association of Clinical Endocrinologists Medical Guidelines for clinical practice for the evaluation and treatment of hypogonadism in adult male patients—2002 update. Endocr Pract 2002 Nov-Dec 8 440 56 Wu FC , Tajar A , Beynon JM , et al EMAS Group Identification of late-onset hypogonadism in middle-aged and elderly men. N Engl J Med 2010 363 123 35 Bassil N , Morley JE . Late-life onset hypogonadism: a review (...) . Clin Geriatr Med 2010 26 197 222 Nguyen CP , Hirsch MS , Moeny D , et al Testosterone and “Age-related hypogonadism”—FDA concerns. N Engl J Med 2015 373 689 91 Diem SJ , Greer NL , MacDonald R , et al Efficacy and safety of testosterone treatment in men: an evidence report for a clinical practice guideline by the American College of Physicians. Ann Intern Med 7 January 2020 [Epub ahead of print] Qaseem A , Kansagara D , Lin JS , et al Clinical Guidelines Committee of the American College

2020 American College of Physicians

11. Randomized clinical trial of intraoperative dexmedetomidine to prevent delirium in the elderly undergoing major non-cardiac surgery Full Text available with Trip Pro

in elderly patients after surgery and is associated with poor outcomes. This study aimed to investigate the impact of intraoperative dexmedetomidine on the incidence of delirium in elderly patients undergoing major surgery. Methods: This was a randomized double-blind placebo-controlled trial. Elderly patients (aged 60 years or more) scheduled to undergo major non-cardiac surgery were randomized into two groups. Patients in the intervention group received a loading dose of dexmedetomidine 0·6 μg/kg 10 min (...) Randomized clinical trial of intraoperative dexmedetomidine to prevent delirium in the elderly undergoing major non-cardiac surgery Randomized Clinical Trial of Intraoperative Dexmedetomidine to Prevent Delirium in the Elderly Undergoing Major Non-Cardiac Surgery - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced

2020 EvidenceUpdates

12. Validation of the Elderly Risk Assessment Index in the Emergency Department (Abstract)

Validation of the Elderly Risk Assessment Index in the Emergency Department The Elderly Risk Assessment (ERA) score is a validated index for primary care patients that predict hospitalizations, mortality, and Emergency Department (ED) visits. The score incorporates age, prior hospital days, marital status, and comorbidities. Our aim was to validate the ERA score in ED patients.Observational cohort study of patients age ≥ 60 presenting to an academic ED over a 1-year period. Regression analyses (...) were performed for associations with outcomes (hospitalization, return visits and death). Medians, interquartile range (IQR), odds ratios (OR) and 95% confidence intervals (CI) were calculated.The cohort included 27,397 visits among 18,607 patients. Median age 74 years (66-82), 48% were female and 59% were married. Patients from 54% of visits were admitted to the hospital, 16% returned to the ED within 30 days, and 18% died within one year. Higher ERA scores were associated with: hospital admission

2020 EvidenceUpdates

13. Treatment of Older Patients With Mantle Cell Lymphoma (MCL): Long-Term Follow-Up of the Randomized European MCL Elderly Trial

Treatment of Older Patients With Mantle Cell Lymphoma (MCL): Long-Term Follow-Up of the Randomized European MCL Elderly Trial Treatment of Older Patients With Mantle Cell Lymphoma (MCL): Long-Term Follow-Up of the Randomized European MCL Elderly Trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced features (...) a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation J Clin Oncol Actions , 38 (3), 248-256 2020 Jan 20 Treatment of Older Patients With Mantle Cell Lymphoma (MCL): Long-Term Follow-Up of the Randomized European MCL Elderly Trial , , , , , , , , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 University Medical Center Groningen

2020 EvidenceUpdates

14. Developing an all-age response to meet the age-specific needs of service users

Developing an all-age response to meet the age-specific needs of service users NHS England » Developing an all-age response to meet the age-specific needs of service users Search Search Menu Developing an all-age response to meet the age-specific needs of service users Document first published: 22 January 2020 Page updated: 22 January 2020 Topic: Publication type: Document PDF 476 KB 14 pages

2020 NHS England

15. Incident psychiatric comorbidity following stress disorder diagnoses in Danish school-aged children: prospective population-based study

Incident psychiatric comorbidity following stress disorder diagnoses in Danish school-aged children: prospective population-based study Incident Psychiatric Comorbidity Following Stress Disorder Diagnoses in Danish School-Aged Children: Prospective Population-Based Study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other (...) characters Choose a collection: Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Br J Psychiatry Actions , 1-6 2019 Nov 22 [Online ahead of print] Incident Psychiatric Comorbidity Following Stress Disorder Diagnoses in Danish School-Aged Children: Prospective Population-Based Study , , , , , , Affiliations Expand Affiliations 1 Research Associate

2020 EvidenceUpdates

16. Physical Activity: Digital Health Interventions for Adults 55 Years and Older

Studies The number of studies and publications do not always correspond (e.g., a publication may include several studies or one study may be explained in several publications). . Bickmore TW, Silliman RA, Nelson K, Cheng DM, Winter M, et al.. A randomized controlled trial of an automated exercise coach for older adults. J Am Geriatr Soc 2013;61:1676–83. Freene N. Physiotherapist-led home-based physical activity program versus community group exercise for middle-aged adults: quasi-experimental (...) , Castro CM, et al. Promoting physical activity through hand-held computer technology. Am J Prev Med 2008;34:138–42. King AC, Bickmore TW, Campero MI, Pruitt LA, Yin JL. Employing virtual advisors in preventive care for underserved communities: results from the COMPASS study. J Health Commun 2013b;18:1449–64. Kolt GS, Schofield GM, Kerse N, Garrett N, Oliver M. Effect of telephone counseling on physical activity for low-active older people in primary care: a randomized, controlled trial. J Am Geriatr

2020 Community Preventive Services Task Force

17. Guidance for Providers Caring for Women and Men Of Reproductive Age with Possible Zika Virus Exposure

Guidance for Providers Caring for Women and Men Of Reproductive Age with Possible Zika Virus Exposure -1- Guidance for Providers Caring for Women and Men Of Reproductive Age with Possible Zika Virus Exposure (Modified from CDC a- i FDA j-l and WHO k Published Guidance) Updated July 2019 Planning Pregnancy for Infected, Exposed, or Possibly Exposed Individuals This is an update of the ASRM Zika virus guidance for providers that addresses the care of non-pregnant patients desiring pregnancy (...) taking into account any new available data and such variables as age of the female patient and other infertility factors with documentation of the conversation and decision. 4. Symptomatic women and men attempting pregnancy through ART with possible Zika virus exposure should have testing that includes the Zika virus nucleic acid test (NAT) to rule out active Zika infection, and serologic testing, as outlined in section #8 below, to identify Zika immunity, before proceeding on with infertility

2020 Society for Assisted Reproductive Technology

18. Best-practice prevention alone or with conventional or biological caries management for 3- to 7-year-olds: the FiCTION three-arm RCT

Best-practice prevention alone or with conventional or biological caries management for 3- to 7-year-olds: the FiCTION three-arm RCT Best-practice prevention alone or with conventional or biological caries management for 3- to 7-year-olds: the FiCTION three-arm RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try

2020 NIHR HTA programme

19. Combination non-pharmacologic intervention for orthostatic hypotension in older people: a phase 2 study Full Text available with Trip Pro

to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Age Ageing Actions 2019 Dec 23 [Online ahead of print] Combination Non-Pharmacologic Intervention for Orthostatic Hypotension in Older People: A Phase 2 Study , Affiliations Expand Affiliations 1 Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. 2 The Falls and Syncope Service, Newcastle upon Tyne (...) Hospitals NHS Foundation Trust, Newcastle upon Tyne NE1 4LP, UK. 3 NIHR Newcastle Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Trust and Newcastle University, Newcastle upon Tyne, UK. PMID: 31868889 DOI: Item in Clipboard Combination Non-Pharmacologic Intervention for Orthostatic Hypotension in Older People: A Phase 2 Study James Frith et al. Age Ageing . 2019 Show details Age Ageing Actions Authors , Affiliations 1 Institute of Cellular Medicine, Newcastle University, Newcastle upon

2020 EvidenceUpdates

20. Effect of Sex, Age, and Positivity Threshold on Fecal Immunochemical Test Accuracy: A Systematic Review and Meta-analysis Full Text available with Trip Pro

Effect of Sex, Age, and Positivity Threshold on Fecal Immunochemical Test Accuracy: A Systematic Review and Meta-analysis Effect of Sex, Age, and Positivity Threshold on Fecal Immunochemical Test Accuracy: A Systematic Review and Meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Welcome to the new PubMed. For legacy PubMed go to . Clipboard, Search History, and several other advanced features are temporarily (...) : Unable to load your collection due to an error Add Cancel Add to My Bibliography My Bibliography Unable to load your delegates due to an error Add Cancel Actions Cite Share Permalink Copy Page navigation Meta-Analysis Gastroenterology Actions , 157 (6), 1494-1505 Dec 2019 Effect of Sex, Age, and Positivity Threshold on Fecal Immunochemical Test Accuracy: A Systematic Review and Meta-analysis , , , , , , , Affiliations Expand Affiliations 1 Kaiser Permanente Division of Research, Oakland, California

2020 EvidenceUpdates