Latest & greatest articles for docusate

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on docusate or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on docusate and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for docusate

1. Metapopulation Structure of CRISPR-Cas Immunity in Pseudomonas aeruginosa and Its Viruses (PubMed)

Metapopulation Structure of CRISPR-Cas Immunity in Pseudomonas aeruginosa and Its Viruses 30374457 2018 11 14 2379-5077 3 5 2018 Sep-Oct mSystems mSystems Metapopulation Structure of CRISPR-Cas Immunity in Pseudomonas aeruginosa and Its Viruses. e00075-18 10.1128/mSystems.00075-18 Viruses that infect the widespread opportunistic pathogen Pseudomonas aeruginosa have been shown to influence physiology and critical clinical outcomes in cystic fibrosis (CF) patients. To understand how CRISPR-Cas

Full Text available with Trip Pro

2018 mSystems

2. Empagliflozin reduces Ca/calmodulin‐dependent kinase II activity in isolated ventricular cardiomyocytes (PubMed)

Empagliflozin reduces Ca/calmodulin‐dependent kinase II activity in isolated ventricular cardiomyocytes 30117720 2018 11 14 2055-5822 5 4 2018 08 ESC heart failure ESC Heart Fail Empagliflozin reduces Ca/calmodulin-dependent kinase II activity in isolated ventricular cardiomyocytes. 642-648 10.1002/ehf2.12336 The EMPA-REG OUTCOME study showed reduced mortality and hospitalization due to heart failure (HF) in diabetic patients treated with empagliflozin. Overexpression and Ca 2+ -dependent (...) activation of Ca 2+ /calmodulin-dependent kinase II (CaMKII) are hallmarks of HF, leading to contractile dysfunction and arrhythmias. We tested whether empagliflozin reduces CaMKII- activity and improves Ca 2+ -handling in human and murine ventricular myocytes. Myocytes from wild-type mice, mice with transverse aortic constriction (TAC) as a model of HF, and human failing ventricular myocytes were exposed to empagliflozin (1 μmol/L) or vehicle. CaMKII activity was assessed by CaMKII-histone deacetylase

Full Text available with Trip Pro

2018 ESC heart failure

3. CA-125 Significance in Cirrhosis and Correlation with Disease Severity and Portal Hypertension: A Retrospective Study (PubMed)

CA-125 Significance in Cirrhosis and Correlation with Disease Severity and Portal Hypertension: A Retrospective Study 30271734 2018 11 14 2225-0719 6 3 2018 Sep 28 Journal of clinical and translational hepatology J Clin Transl Hepatol CA-125 Significance in Cirrhosis and Correlation with Disease Severity and Portal Hypertension: A Retrospective Study. 241-246 10.14218/JCTH.2017.00070 Background and Aims: To evaluate the prevalence and significance of elevated cancer antigen-125 (CA-125) levels (...) in patients with cirrhosis being treated in a tertiary care liver center and its correlation with objective markers of disease severity. Methods: We retrospectively reviewed medical records of 172 adult patients with cirrhosis (due to any etiology) after obtaining CA-125 serum analysis. Demographics, etiology of cirrhosis, model of end-stage liver disease (MELD) score, Child's Turcotte-Pugh classification, albumin bilirubin (ALBI) score, degree of ascites, presence of esophageal varices, serum CA-125

Full Text available with Trip Pro

2018 Journal of clinical and translational hepatology

4. Monthly report on dracunculiasis cases, January-November 2017 – Rapport mensuel des cas de dracunculose, janvier-novembre 2017

Monthly report on dracunculiasis cases, January-November 2017 – Rapport mensuel des cas de dracunculose, janvier-novembre 2017 WHO IRIS: Monthly report on dracunculiasis cases, January-November 2017 – Rapport mensuel des cas de dracunculose, janvier-novembre 2017 Browse Related links Files in This Item: File Description Size Format 172.54 kB Adobe PDF Title: Monthly report on dracunculiasis cases, January-November 2017 – Rapport mensuel des cas de dracunculose, janvier-novembre 2017 Authors

2018 WHO

5. The Age of BLood Evaluation (ABLE) randomised controlled trial: description of the UK-funded arm of the international trial, the UK cost-utility analysis and secondary analyses exploring factors associated with health-related quality of life and health-ca

The Age of BLood Evaluation (ABLE) randomised controlled trial: description of the UK-funded arm of the international trial, the UK cost-utility analysis and secondary analyses exploring factors associated with health-related quality of life and health-ca The Age of BLood Evaluation (ABLE) randomised controlled trial: description of the UK-funded arm of the international trial, the UK cost-utility analysis and secondary analyses exploring factors associated with health-related quality

2017 NIHR HTA programme

6. Monthly report on dracunculiasis cases, January-September 2017 – Rapport mensuel des cas de dracunculose, janvier-septembre 2017

Monthly report on dracunculiasis cases, January-September 2017 – Rapport mensuel des cas de dracunculose, janvier-septembre 2017 WHO IRIS: Monthly report on dracunculiasis cases, January-September 2017 – Rapport mensuel des cas de dracunculose, janvier-septembre 2017 Browse Related links Files in This Item: File Description Size Format 174.38 kB Adobe PDF Title: Monthly report on dracunculiasis cases, January-September 2017 – Rapport mensuel des cas de dracunculose, janvier-septembre 2017

2017 WHO

7. Jayappa KD, Portell CA, Gordon VL, et al. Microenvironmental agonists generate de novo phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL. Blood Adv. 2017;1(14):933-946. (PubMed)

Jayappa KD, Portell CA, Gordon VL, et al. Microenvironmental agonists generate de novo phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL. Blood Adv. 2017;1(14):933-946. 29297516 2018 10 25 2473-9529 1 19 2017 08 22 Blood advances Blood Adv Erratum: Jayappa KD, Portell CA, Gordon VL, et al. Microenvironmental agonists generate de novo phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL. Blood Adv. 2017;1(14):933-946. 1537 10.1182/bloodadvances

Full Text available with Trip Pro

2017 Blood advances

8. Monthly report on dracunculiasis cases, January– May 2017 – Rapport mensuel des cas de dracunculose, janvier-mai 2017

Monthly report on dracunculiasis cases, January– May 2017 – Rapport mensuel des cas de dracunculose, janvier-mai 2017 WHO IRIS: Monthly report on dracunculiasis cases, January– May 2017 – Rapport mensuel des cas de dracunculose, janvier-mai 2017 Browse Related links Files in This Item: File Description Size Format 169.2 kB Adobe PDF Title: Monthly report on dracunculiasis cases, January– May 2017 – Rapport mensuel des cas de dracunculose, janvier-mai 2017 Authors: Issue Date: 14-Jul-2017

2017 WHO

9. Monthly report on dracunculiasis cases, January– April 2017 – Rapport mensuel des cas de dracunculose, janvier-avril 2017

Monthly report on dracunculiasis cases, January– April 2017 – Rapport mensuel des cas de dracunculose, janvier-avril 2017 WHO IRIS: Monthly report on dracunculiasis cases, January– April 2017 – Rapport mensuel des cas de dracunculose, janvier-avril 2017 Browse Related links Files in This Item: File Description Size Format 180.46 kB Adobe PDF Title: Monthly report on dracunculiasis cases, January– April 2017 – Rapport mensuel des cas de dracunculose, janvier-avril 2017 Authors: Issue Date: 9-Jun

2017 WHO

10. Why Gene Editors Like CRISPR/Cas May Be a Game-Changer for Neuroweapons (PubMed)

Why Gene Editors Like CRISPR/Cas May Be a Game-Changer for Neuroweapons 28574731 2018 04 09 2018 12 02 2326-5108 15 3 2017 May/Jun Health security Health Secur Why Gene Editors Like CRISPR/Cas May Be a Game-Changer for Neuroweapons. 296-302 10.1089/hs.2016.0120 This year marks the Eighth Review Conference (RevCon) of the Biological Toxins and Weapons Convention (BWC). At the same time, ongoing international efforts to further and more deeply investigate the brain's complex neuronal circuitry (...) categorizations of weaponizable tools and substances, so as to better inform and generate tractable policy to enable improved surveillance and governance of novel neuroweapons. DiEuliis Diane D Giordano James J eng UL1 TR001409 TR NCATS NIH HHS United States Journal Article 2017 06 02 United States Health Secur 101654694 2326-5094 IM Bioterrorism CRISPR-Cas Systems Clustered Regularly Interspaced Short Palindromic Repeats genetics Gene Targeting Genetic Engineering methods Humans Biosecurity policy CRISPR

Full Text available with Trip Pro

2017 Health security

11. Persistent Elevation of CA 19-9 Levels in the Long-term Follow-up before Laryngeal Cancer (PubMed)

Persistent Elevation of CA 19-9 Levels in the Long-term Follow-up before Laryngeal Cancer 29201783 2018 11 13 2231-5047 7 1 2017 Jan-Jun Euroasian journal of hepato-gastroenterology Euroasian J Hepatogastroenterol Persistent Elevation of CA 19-9 Levels in the Long-term Follow-up before Laryngeal Cancer. 92-94 10.5005/jp-journals-10018-1222 CA 19-9 is used as a tumor marker in colon, pancreas, biliary, and gastric cancers. Laryngeal cancer is the most common malignant epithelial tumor among head (...) and neck cancers and has no specific tumor marker. A 66-year-old male patient had severe reflux symptoms during 5 years and had an isolated CA 19-9 elevation. Follow-up analysis revealed that he had larynx cancer and after laryngectomy, CA 19-9 levels decreased to normal range. Currently, CA 19-9 is not a marker for malignancy. Laryngeal carcinoma has no specific tumor marker, but laryngeal squamous cell carcinoma may be manifested by elevated CA 19-9 levels. How to cite this article: Özkan H, Karakaya

Full Text available with Trip Pro

2017 Euroasian journal of hepato-gastroenterology

12. Is CA 19-9 of Any Help in the Management of Cholangiocarcinoma? (PubMed)

Is CA 19-9 of Any Help in the Management of Cholangiocarcinoma? 28848793 2018 11 13 2341-4545 24 3 2017 May GE Portuguese journal of gastroenterology GE Port J Gastroenterol Is CA 19-9 of Any Help in the Management of Cholangiocarcinoma? 108-109 10.1159/000457910 Cravo Marília M Gastroenterology Department, Hospital Beatriz Ângelo, Loures, Portugal. eng Editorial 2017 03 23 Switzerland GE Port J Gastroenterol 101685861 2387-1954 CA 19-9 Cholangiocarcinoma Prognosis 2017 01 24 2017 01 25 2017 8

Full Text available with Trip Pro

2017 GE Portuguese journal of gastroenterology

13. CA 19-9 as a Marker of Survival and a Predictor of Metastization in Cholangiocarcinoma (PubMed)

CA 19-9 as a Marker of Survival and a Predictor of Metastization in Cholangiocarcinoma 28848795 2018 11 13 2341-4545 24 3 2017 May GE Portuguese journal of gastroenterology GE Port J Gastroenterol CA 19-9 as a Marker of Survival and a Predictor of Metastization in Cholangiocarcinoma. 114-121 10.1159/000452691 Cholangiocarcinoma is the second most frequent primitive liver malignancy and is responsible for 3% of the malignant gastrointestinal neoplasms. The aims of this study were to determine (...) the association of serum levels of CA 19-9 at diagnosis with other clinical data and serum liver function tests and to identify possible factors that influence the survival rates during follow-up. Retrospective observational study of 89 patients with a diagnosis of cholangiocarcinoma followed at the Department of Gastroenterology during 5 years. Statistical analyses were performed using SPSS version 20.0. Patients were followed up for a median time of 127 days (IQR: 48-564), and the median age at diagnosis

Full Text available with Trip Pro

2017 GE Portuguese journal of gastroenterology

14. Monthly report on dracunculiasis cases, January–October 2016 = Rapport mensuel des cas de dracunculose, janvier-octobre 2016

Monthly report on dracunculiasis cases, January–October 2016 = Rapport mensuel des cas de dracunculose, janvier-octobre 2016 WHO IRIS: Monthly report on dracunculiasis cases, January–October 2016 = Rapport mensuel des cas de dracunculose, janvier-octobre 2016 Browse Related links Files in This Item: File Description Size Format 171.51 kB Adobe PDF Title: Monthly report on dracunculiasis cases, January–October 2016 = Rapport mensuel des cas de dracunculose, janvier-octobre 2016 Authors: Issue

2016 WHO

15. Peritoneal tuberculosis with elevated CA-125 mimicking ovarian cancer with carcinomatosis peritonei: Crucial CT findings (PubMed)

Peritoneal tuberculosis with elevated CA-125 mimicking ovarian cancer with carcinomatosis peritonei: Crucial CT findings 28337102 2018 11 13 1611-2156 15 2016 EXCLI journal EXCLI J Peritoneal tuberculosis with elevated CA-125 mimicking ovarian cancer with carcinomatosis peritonei: Crucial CT findings. 711-715 10.17179/excli2016-625 Preoperative diagnosis of peritoneal tuberculosis is often difficult because of confusion with ovarian cancer. A 56-year-old woman was admitted to our hospital (...) with abdominal fullness. Ascites, prominent bilateral ovaries, and elevated CA-125 were noted. Computed tomography showed thickened peritoneum and strandings in the mesentery and omentum. Exploratory laparotomy was performed under the provisional diagnosis of ovarian cancer, but the final diagnosis was peritoneal tuberculosis. Careful evaluation of bilateral fallopian tubes and ovaries and peritoneum are helpful for correct diagnosis. Chien Jerry Chin-Wei JC Department of Radiology, Wan Fang Hospital, Taipei

Full Text available with Trip Pro

2016 EXCLI journal

16. Monthly report on dracunculiasis cases, January-October 2015 = Rapport mensuel des cas de dracunculose, janvier-octobre 2015

Monthly report on dracunculiasis cases, January-October 2015 = Rapport mensuel des cas de dracunculose, janvier-octobre 2015 WHO IRIS: Monthly report on dracunculiasis cases, January-October 2015 = Rapport mensuel des cas de dracunculose, janvier-octobre 2015 Browse Related links Files in This Item: File Description Size Format 540.58 kB Adobe PDF Title: Monthly report on dracunculiasis cases, January-October 2015 = Rapport mensuel des cas de dracunculose, janvier-octobre 2015 Authors: Issue

2015 WHO

17. For Patients with Pulp Necrosis of Immature Permanent Teeth, Revascularization is More Effective Than Ca(OH)2 or MTA Apexification in Increasing Root Length and Width as Well as Improving Overall Survival Rates

For Patients with Pulp Necrosis of Immature Permanent Teeth, Revascularization is More Effective Than Ca(OH)2 or MTA Apexification in Increasing Root Length and Width as Well as Improving Overall Survival Rates UTCAT2677, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title For Patients with Pulp Necrosis of Immature Permanent Teeth, Revascularization is More Effective Than Ca(OH)2 or MTA Apexification in Increasing Root (...) effective than apexification with either Ca(OH)2 or MTA apexification in increasing root length and width as well as improving overall survival rates of teeth. This is supported by a retrospective analysis of 61 cases showing an increase in root length and width by a clinically significant margin through revascularization when compared to a much slimmer margin by CaOH and MTA apexification treatments. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year

2014 UTHSCSA Dental School CAT Library

18. Pre-procedural Risk Quantification for Carotid Stenting Using the CAS Score: A Report From the NCDR CARE Registry (PubMed)

Pre-procedural Risk Quantification for Carotid Stenting Using the CAS Score: A Report From the NCDR CARE Registry 22999733 2012 10 19 2013 01 08 2012 10 19 1558-3597 60 17 2012 Oct 23 Journal of the American College of Cardiology J. Am. Coll. Cardiol. Pre-procedural risk quantification for carotid stenting using the CAS score: a report from the NCDR CARE Registry. 1617-22 10.1016/j.jacc.2012.07.026 S0735-1097(12)02929-4 We developed and internally validated a risk score to predict in-hospital (...) stroke or death after carotid artery stenting (CAS). A tool that accurately assesses CAS risk could aid clinical decision making and improve patient selection. Patients undergoing CAS without acute evolving stroke from April 2005 through June 2011 as part of the NCDR Carotid Artery Revascularization and Endarterectomy (CARE) Registry were included. In-hospital stroke or death was modeled using logistic regression with 35 candidate variables. Internal validation was achieved with bootstrapping

2012 EvidenceUpdates

19. Mineral Trioxide Aggregate As Direct Pulp Capping Cement Is More Effective In Calcified Bridge Formation And Reduction Of Pulp Inflammation Than Dycal and Ca(OH)2

Mineral Trioxide Aggregate As Direct Pulp Capping Cement Is More Effective In Calcified Bridge Formation And Reduction Of Pulp Inflammation Than Dycal and Ca(OH)2 UTCAT2232, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Mineral Trioxide Aggregate As Direct Pulp Capping Cement Is More Effective In Calcified Bridge Formation And Reduction Of Pulp Inflammation Than Dycal and Ca(OH)2 Clinical Question Is Mineral Trioxide (...) ]) AND "Endodontics"[Mesh]) AND "Dental Pulp"[Mesh] Comments on The Evidence Roberts’s article searched 156 citations from scientific, peer-review of dental literature. Authors reported that MTA has a potential to be used in endodontics. However, this report lacked randomized, double-blind clinical studies of long-term follow up to confirm its validity. No meta-analysis was done.Accorinte’s article compared response of tooth pulp when directly capped with MTA vs Ca(OH)2 powder. MTA is found to be better than Ca

2012 UTHSCSA Dental School CAT Library

20. Cancer Health Empowerment for Living without Pain (Ca-HELP): effects of a tailored education and coaching intervention on pain and impairment (PubMed)

Cancer Health Empowerment for Living without Pain (Ca-HELP): effects of a tailored education and coaching intervention on pain and impairment 21439726 2011 06 13 2011 10 13 2011 12 07 1872-6623 152 7 2011 Jul Pain Pain Cancer Health Empowerment for Living without Pain (Ca-HELP): effects of a tailored education and coaching intervention on pain and impairment. 1572-82 10.1016/j.pain.2011.02.047 We aimed to determine the effectiveness of a lay-administered tailored education and coaching (TEC (...) impairment, but no improvement in pain severity. Copyright © 2011 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved. Kravitz Richard L RL Department of Internal Medicine and Center for Healthcare Policy and Research, University of California at Davis, Sacramento, CA 95817, USA. rlkravitz@ucdavis.edu Tancredi Daniel J DJ Grennan Tim T Kalauokalani Donna D Street Richard L RL Jr Slee Christina K CK Wun Ted T Oliver Jennifer Wright JW Lorig Kate K Franks Peter P

2011 EvidenceUpdates