Latest & greatest articles for depression

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Top results for depression

1801. Selective serotonin reuptake inhibitors (SSRIs) for major depression. Part 2. The cost-effectiveness of SSRIs in treatment of depression

Selective serotonin reuptake inhibitors (SSRIs) for major depression. Part 2. The cost-effectiveness of SSRIs in treatment of depression Selective serotonin reuptake inhibitors (SSRIs) for major depression. Part 2. The cost-effectiveness of SSRIs in treatment of depression Selective serotonin reuptake inhibitors (SSRIs) for major depression. Part 2. The cost-effectiveness of SSRIs in treatment of depression Baladi J-F Record Status This is a bibliographic record of a published health technology (...) assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Baladi J-F. Selective serotonin reuptake inhibitors (SSRIs) for major depression. Part 2. The cost-effectiveness of SSRIs in treatment of depression. Canadian Coordinating Office for Health Technology Assessment (CCOHTA). 1997 Authors' objectives This study examines the cost-effectiveness of SSRIs as compared toTCAs in the outpatient treatment of depression. It assesses whether

Health Technology Assessment (HTA) Database.1997

1802. Treating depression in adolescence: a review of the effectiveness of cognitive-behavioral treatments

Treating depression in adolescence: a review of the effectiveness of cognitive-behavioral treatments Treating depression in adolescence: a review of the effectiveness of cognitive-behavioral treatments Treating depression in adolescence: a review of the effectiveness of cognitive-behavioral treatments Marcotte D Authors' objectives To assess the efficacy of cognitive-behavioural approaches in the treatment of adolescents with depression. Searching PsycLIT was searched for studies published (...) in English or French between 1980 and 1994, using the keywords 'adolescence', 'treatment' and 'depression'. Study selection Study designs of evaluations included in the review Studies of the use of cognitive therapy for depressed adolescents were included if the patients with depressive symptoms were selected by some systematic procedure, and if the design included a control group and systematic procedures that were specified in a manual. Case studies and studies that did not use statistical procedures

DARE.1997

1803. The efficacy, safety and tolerability of antidepressants in late life depression: a meta-analysis

The efficacy, safety and tolerability of antidepressants in late life depression: a meta-analysis The efficacy, safety and tolerability of antidepressants in late life depression: a meta-analysis The efficacy, safety and tolerability of antidepressants in late life depression: a meta-analysis Mittmann N, Herrmann N, Einarson T R, Busto U E, Lanctot K L, Liu B A, Shulman K I, Silver I L, Narango C A, Shear N H Authors' objectives To determine the efficacy, safety and tolerability (...) of antidepressants in depressed elderly patients. Searching MEDLINE was searched from 1966 to 1996, and EMBASE from 1974 to 1996. The MEDLINE subject headings were: 'antidepressant agent', 'tricyclic antidepressant (TCA)', 'selective serotonin reuptake inhibitor (SSRI)', 'monoamine oxidase inhibitor (MAOI)', 'antidepressant agent', 'second generation (ATYP)', and individual antidepressant drugs by their non-proprietary name. The searches were limited by the age of the patients (greater than 65 years; 80 years

DARE.1997

1804. Controlled clinical trials of hypericum extracts in depressed patients: an overview

Controlled clinical trials of hypericum extracts in depressed patients: an overview Controlled clinical trials of hypericum extracts in depressed patients: an overview Controlled clinical trials of hypericum extracts in depressed patients: an overview Volz H P Authors' objectives To assess the antidepressant efficacy of hypericum extracts. Searching The author searched MEDLINE (search dates and keywords not reported). Additional data was obtained by asking all manufacturers of hypericum (...) with varying degree of depression (mild to major) classified either by the American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders (DSM-III or DSM-III-R), International Classification of Diseases, 9th and 10th revisions (ICD-9 or -10), or a Hamilton Depression Scale (HAMD) score greater than 15 in 13 of the 15 included studies. Outcomes assessed in the review Scores for rating levels of global and mental states (not stated whether change or end points were used), measured

DARE.1997

1805. Selective serotonin reuptake inhibitors (SSRIs) for major depression. Part 1: evaluation of the clinical literature

Selective serotonin reuptake inhibitors (SSRIs) for major depression. Part 1: evaluation of the clinical literature Selective serotonin reuptake inhibitors (SSRIs) for major depression. Part 1: evaluation of the clinical literature Selective serotonin reuptake inhibitors (SSRIs) for major depression. Part 1: evaluation of the clinical literature Trindade E, Menon D Authors' objectives To review the efficacy and safety of selective serotonin re-uptake inhibitors (SSRIs) when used to treat major (...) depression. Searching MEDLINE, EMBASE, PsycINFO, International Pharmaceutical Abstracts, Pascal, Health Planning and Administration database, Mental Health Abstracts, and PharmacoEconomics and Outcomes News, were searched from 1980 to 1996. Details of the search terms used were provided. In addition, Current Contents was scanned during the course of the project, and journals received by the Canadian Coordinating Office for Health Technology Assessment library were handsearched. The bibliographies from

DARE.1997

1806. Bibliotherapy in unipolar depression: a meta-analysis

Bibliotherapy in unipolar depression: a meta-analysis Bibliotherapy in unipolar depression: a meta-analysis Bibliotherapy in unipolar depression: a meta-analysis Cuijpers P Authors' objectives To compare the effects of bibliotherapy with other treatment methods for unipolar depression. Searching PsycLIT, PsycINFO and MEDLINE were searched. The references of the retrieved publications were also examined. Study selection Study designs of evaluations included in the review Randomised controlled (...) ; and cognitive bibliotherapy. The control groups received either individual or group therapy, or were on a waiting-list to receive treatment. Participants included in the review The participants were recruited through announcements in the media. Four of the six studies used 'adults' while the remaining two used 'elderly'. The participants' diagnoses were not stated. Outcomes assessed in the review Depression was assessed using the following: the Beck Depression Inventory; the Hamilton Rating Scale

DARE.1997

1807. A meta-analysis of the effect of hormone replacement therapy upon depressed mood

A meta-analysis of the effect of hormone replacement therapy upon depressed mood A meta-analysis of the effect of hormone replacement therapy upon depressed mood A meta-analysis of the effect of hormone replacement therapy upon depressed mood Zweifel J E, O'Brien W H Authors' objectives To address fundamental questions about the effectiveness of hormone replacement therapy (HRT) on menopausal depressed mood. In particular, the authors sought to evaluate the following: the overall effect of HRT (...) upon depressed mood; and the extent to which treatment effects (type of HRT, dose, length of treatment, and route of administration) and methodological factors accounted for variance in treatment outcomes. Searching Three search strategies were employed to locate relevant studies. 1. A computer-aided search was conducted of Psychological Abstracts (from 1974 to November 1995) and MEDLINE (from 1966 to November 1995), using four key terms: 'Menopause and Drug Therapy', 'Menopause and Depression

DARE.1997

1808. Alprazolam and standard antidepressants in the treatment of depression: a meta-analysis of the antidepressant effect

Alprazolam and standard antidepressants in the treatment of depression: a meta-analysis of the antidepressant effect Alprazolam and standard antidepressants in the treatment of depression: a meta-analysis of the antidepressant effect Alprazolam and standard antidepressants in the treatment of depression: a meta-analysis of the antidepressant effect Srisurapanont M, Boonyanaruthee V Authors' objectives To compare the effectiveness of alprazolam and standard antidepressants in the treatment (...) of depression. Searching MEDLINE was searched up to June 1995 using the following headings and terms: 'depressive disorder-drug therapy', 'alprazolam', 'antidepressants' and 'randomised-controlled trial'. Cross-referencing was used to seek out further studies. Study selection Study designs of evaluations included in the review Double-blind, randomised controlled trials (RCTs), which compared the antidepressant effect of alprazolam to that of a standard antidepressant, were included if they measured

DARE.1997

1809. Fluvoxamine: a review of the controlled trials in depression

Fluvoxamine: a review of the controlled trials in depression Fluvoxamine: a review of the controlled trials in depression Fluvoxamine: a review of the controlled trials in depression Ware M R Authors' objectives To review the safety and efficacy of fluvoxamine in the pharmacotherapy of depression. Searching MEDLINE was searched to identify English language trials. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs), which were double-blind (...) and placebo- and drug-controlled, were included. Twenty out of the 31 trials had a single-blind placebo washout prior to randomisation. Specific interventions included in the review Fluvoxamine compared with placebo, imipramine, clomipramine, tricyclics, mianserin and other antidepressants. Participants included in the review Participants with depression. Diagnostic criteria varied amongst studies. All but three trials, however, employed American Psychiatric Association criteria (DSM-III, DSM-III-R

DARE.1997

1810. Pharmacoeconomic analysis of venlafaxine in the treatment of major depressive disorder

Pharmacoeconomic analysis of venlafaxine in the treatment of major depressive disorder Pharmacoeconomic analysis of venlafaxine in the treatment of major depressive disorder Pharmacoeconomic analysis of venlafaxine in the treatment of major depressive disorder Einarson T R, Addis A, Iskedjian M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions (...) followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Venlafaxine in the treatment of acute depressive disorders. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population Patient characteristics are published elsewhere, with a meta-analysis of effectiveness data. Setting Inpatient and outpatient settings were included. The economic analysis was carried out in Ontario, Canada. Dates to which data

NHS Economic Evaluation Database.1997

1811. A clinical and economic evaluation of selective serotonin reuptake inhibitors in major depression

A clinical and economic evaluation of selective serotonin reuptake inhibitors in major depression A clinical and economic evaluation of selective serotonin reuptake inhibitors in major depression A clinical and economic evaluation of selective serotonin reuptake inhibitors in major depression Ausejo M, Glennie J L Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods (...) , the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Selective serotonin reuptake inhibitors (SSRIs) for first line treatment of depression. Type of intervention Treatment and rehabilitation. Economic study type Cost-effectiveness analysis and cost-utility analysis. Study population Male and female patients, over 18 years of age, and suffering from depression. Setting Hospital and community. The economic study

NHS Economic Evaluation Database.1997

1812. Economic evaluation of paroxetine and imipramine in depressed outpatients

Economic evaluation of paroxetine and imipramine in depressed outpatients Economic evaluation of paroxetine and imipramine in depressed outpatients Economic evaluation of paroxetine and imipramine in depressed outpatients Melton S T, Kirkwood C K, Farrar T W, Brink D D, Carroll N V Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed (...) by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Imipramine and paroxetine in treating depression in outpatients. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study population identified consisted of patients who were prescribed one of the two drugs (paroxetine or imipramine) for the treatment of depression under the care of a psychiatrist. Setting The setting was tertiary care (a hospital

NHS Economic Evaluation Database.1997

1813. Selective serotonin reuptake inhibitors (SSRIs) for major depression. Part I. Evaluation of the clinical literature

Selective serotonin reuptake inhibitors (SSRIs) for major depression. Part I. Evaluation of the clinical literature Selective serotonin reuptake inhibitors (SSRIs) for major depression. Part I. Evaluation of the clinical literature Selective serotonin reuptake inhibitors (SSRIs) for major depression. Part I. Evaluation of the clinical literature Trindade E, Menon D Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation (...) of the quality of this assessment has been made for the HTA database. Citation Trindade E, Menon D. Selective serotonin reuptake inhibitors (SSRIs) for major depression. Part I. Evaluation of the clinical literature. Ottawa: Canadian Coordinating Office for Health Technology Assessment/Office Canadien de Coordination de l'Evaluation des Technologies de la Sante (CCOHTA) 1997: 45 Authors' objectives To review the literature relating to the use of SSRIs in major depression. Authors' conclusions Efficacy

Health Technology Assessment (HTA) Database.1997

1814. Relapse of depression after rapid depletion of tryptophan.

Relapse of depression after rapid depletion of tryptophan. 9093253 1997 04 25 1997 04 25 2015 11 19 0140-6736 349 9056 1997 Mar 29 Lancet (London, England) Lancet Relapse of depression after rapid depletion of tryptophan. 915-9 Major depression is a common disorder but the pathophysiology is poorly understood. Current hypotheses implicate deficient function of brain serotonin pathways because drugs that selectively increase brain serotonin activity are effective antidepressants. However (...) , there is no direct evidence that lowered serotonin function causes major depression. We aimed to assess whether lowering of brain serotonin activity by depletion of its amino acid precursor, tryptophan, could provoke a short-term relapse of clinically significant symptoms in women vulnerable to major depressive disorder. We studied 15 women who had suffered recurrent episodes of major depression but had recovered and were no longer on drug treatment. Patients received two amino acid mixtures in a double-blind

Lancet1997

1815. A controlled study of fluoxetine and cognitive-behavioural counselling in the treatment of postnatal depression.

A controlled study of fluoxetine and cognitive-behavioural counselling in the treatment of postnatal depression. 9099116 1997 04 30 1997 04 30 2013 11 21 0959-8138 314 7085 1997 Mar 29 BMJ (Clinical research ed.) BMJ A controlled study of fluoxetine and cognitive-behavioural counselling in the treatment of postnatal depression. 932-6 To study the effectiveness of fluoxetine and cognitive-behavioural counselling in depressive illness in postnatal women: to compare fluoxetine and placebo, six (...) sessions and one session of counselling, and combinations of drugs and counselling. Randomised, controlled treatment trial, double blind in relation to drug treatment, with four treatment cells: fluoxetine or placebo plus one or six sessions of counselling. 87 women satisfying criteria for depressive illness 6-8 weeks after childbirth, 61 (70%) of whom completed 12 weeks of treatment. Community based study in south Manchester. Psychiatric morbidity after 1, 4, and 12 weeks, measured as mean scores

BMJ1997 Full Text: Link to full Text with Trip Pro

1816. Maintenance treatment of major depression: a review of the literature

Maintenance treatment of major depression: a review of the literature Maintenance treatment of major depression: a review of the literature Maintenance treatment of major depression: a review of the literature Blacker D Authors' objectives To assess the efficacy of maintenance treatments for major depressive disorder (MDD). Searching The literature search began with the American Psychiatric Association's references from "Practice Guideline for Major Depressive Disorder in Adults covering (...) the period 1971 through 1991, and extended the search of the MEDLINE database through 1992 using the search terms 'affective disorder', 'major depression', 'depressive disorder', 'seasonal affective disorder', 'melancholia', 'unipolar depression', 'endogenous depression', 'dysthymic disorder', postpartum depression', pseudodementia', 'antidepressant drugs', 'trycyclic antidepressive agents', 'monoamine oxidase inhibitors', lithium', and 'electroconvulsive therapy'. An additional search of MEDLINE

DARE.1996

1817. The dexamethasone suppression test for diagnosing depression in stroke patients

The dexamethasone suppression test for diagnosing depression in stroke patients The dexamethasone suppression test for diagnosing depression in stroke patients The dexamethasone suppression test for diagnosing depression in stroke patients Harvey S A, Black K J Authors' objectives To evaluate the literature on the dexamethasone suppression test (DST) as a diagnostic tool for depression in stroke patients. Searching MEDLINE, Current Contents and PsycINFO were searched using the keywords (explode (...) ) 'cerebrovascular disorders' and 'dexamethasone'. Sources cited in a recent review were also checked. Study selection Study designs of evaluations included in the review 'Clinical studies' with sample sizes of 20 or more. These were not further defined in terms of methodological features. Specific interventions included in the review Studies of the DST for depression were eligible for inclusion. Reference standard test against which the new test was compared The reference assessments included the Hamilton

DARE.1996

1818. Selective serotonin reuptake inhibitors (SSRIs) in the treatment of elderly depressed patients: a qualitative analysis of the literature on their efficacy and side-effects

Selective serotonin reuptake inhibitors (SSRIs) in the treatment of elderly depressed patients: a qualitative analysis of the literature on their efficacy and side-effects Selective serotonin reuptake inhibitors (SSRIs) in the treatment of elderly depressed patients: a qualitative analysis of the literature on their efficacy and side-effects Selective serotonin reuptake inhibitors (SSRIs) in the treatment of elderly depressed patients: a qualitative analysis of the literature on their efficacy (...) and side-effects Menting J E, Honig A, Verhey F R, Hartmans M, Rozendaal N, de Vet H C, van Praag H M Authors' objectives To assess the efficacy and side-effects of selective serotonin re-uptake inhibitors (SSRIs) for the treatment of elderly people with depression. Searching MEDLINE was searched from January 1980 until December 1994 using the keywords 'fluvoxamine', 'paroxetine', 'fluoxetine' and 'sertraline' combined with 'aged', 'elderly' or 'geriatric'. The citations in all of the identified papers

DARE.1996

1819. Triiodothyronine augmentation in the treatment of refractory depression: a meta-analysis

Triiodothyronine augmentation in the treatment of refractory depression: a meta-analysis Triiodothyronine augmentation in the treatment of refractory depression: a meta-analysis Triiodothyronine augmentation in the treatment of refractory depression: a meta-analysis Aronson R, Offman H J, Joffe R T, Naylor C D Authors' objectives To assess the effectiveness of comparative clinical trials of adjunctive liothyronine sodium (triiodothyronine, T3) in euthyroid nonpsychotic depressed patients (...) . Specific interventions included in the review Tricyclic antidepressant therapy (imipramine hydrochloride, desipramine hydrochloride, amitriptyline hydrochloride) augmented by T3 or placebo. Participants included in the review Male and female depressed adult patients (both unipolar and bipolar) treated in in- and out-patient settings, for whom there was biochemical evidence of euthyroidism. Outcomes assessed in the review Rates of response as defined by each investigator; change in mean scores

DARE.1996

1820. St John's wort for depression: an overview and meta-analysis of randomised clinical trials

St John's wort for depression: an overview and meta-analysis of randomised clinical trials St John's wort for depression: an overview and meta-analysis of randomised clinical trials St John's wort for depression: an overview and meta-analysis of randomised clinical trials Linde K, Ramirez G, Mulrow C D, Pauls A, Weidenhammer W, Melchart D Authors' objectives To investigate if extracts of Hypericum perforatum (St John's Wort) are more effective than placebo in the treatment of depression (...) , amitriptyline, diazepam, desipramine and imipramine. Participants included in the review People with depressive disorders, mainly classed as mild-to-moderate severe depression, were included. Outcomes assessed in the review All clinical outcome measures, such as depression scales or symptoms, were assessed. The most frequently used scales were the Hamilton Depression Scale and the Clinical Global Impression Index. Trials which measured physiological parameters only were excluded. The number of patients

DARE.1996