Latest & greatest articles for depression

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Top results for depression

1801. Efficacy of tricyclic drugs in treating child and adolescent depression: a meta-analysis

Efficacy of tricyclic drugs in treating child and adolescent depression: a meta-analysis Efficacy of tricyclic drugs in treating child and adolescent depression: a meta-analysis Efficacy of tricyclic drugs in treating child and adolescent depression: a meta-analysis Hazell P, O'Connell D, Heathcote D, Robertson J, Henry D Authors' objectives To determine the efficacy of tricyclic antidepressants in the treatment of child and adolescent depression. Searching CD ROM databases of MEDLINE (...) included in the review Randomised controlled trials (RCTs) were included. Specific interventions included in the review Tricyclic drugs: amitriptyline, clomipramine, desipramine, imipramine and nortriptyline. Participants included in the review Children and adolescents between 6 and 18 years, diagnosed as having a depressive illness and an IQ over 80. Participants were treated on either an inpatient or outpatient basis, and were both male and female. Outcomes assessed in the review Two main outcomes

1995 DARE.

1802. Direct cost of depression: analysis of treatment costs of paroxetine versus imipramine in Canada

Direct cost of depression: analysis of treatment costs of paroxetine versus imipramine in Canada Direct cost of depression: analysis of treatment costs of paroxetine versus imipramine in Canada Direct cost of depression: analysis of treatment costs of paroxetine versus imipramine in Canada Lapierre Y, Bentkover J, Schainbaum S, Manners S Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary (...) of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Paroxetine (selective serotonin reuptake inhibitor) and Imipramine (tricyclic antidepressant). Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study modelled individuals with moderate to severe depression. Setting Primary care. The economic study was carried out in Canada. Dates to which data

1995 NHS Economic Evaluation Database.

1803. Pharmacoeconomic issues in the treatment of depression

Pharmacoeconomic issues in the treatment of depression Pharmacoeconomic issues in the treatment of depression Pharmacoeconomic issues in the treatment of depression Cohen L J Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology (...) Primary care treatment and management of depression using the anti-depressants imipramine HC1 and paroxetine HC1. Type of intervention Treatment. Economic study type Cost-effectiveness analysis (cost-minimisation analysis). Study population Outpatients between the ages of 18 and 65 meeting the DSM III or III-R criteria for a major depressive episode with a score greater than 18 on the first 17 items of the Hamilton Rating Scale for Depression (HSRD) and a Rask depression score greater than the Covi

1995 NHS Economic Evaluation Database.

1804. Cost utility analysis of maintenance treatment for recurrent depression

Cost utility analysis of maintenance treatment for recurrent depression Cost utility analysis of maintenance treatment for recurrent depression Cost utility analysis of maintenance treatment for recurrent depression Kamlet M S, Paul N, Greenhouse J, Kupfer D, Frank E, Wade M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed (...) critical assessment on the reliability of the study and the conclusions drawn. Health technology Maintenance treatments for recurrent depression, including interpersonal therapy, imipramine therapy (drug), and a combination of the two. Type of intervention Treatment. Economic study type Cost-utility analysis. Study population Patients with recurrent depression. Setting Hospital and community. The economic study was performed in Pittsburgh, USA. Dates to which data relate Effectiveness and resource use

1995 NHS Economic Evaluation Database.

1805. A Markov process analysis comparing the cost effectiveness of maintenance therapy with citalopram versus standard therapy in major depression

A Markov process analysis comparing the cost effectiveness of maintenance therapy with citalopram versus standard therapy in major depression A Markov process analysis comparing the cost effectiveness of maintenance therapy with citalopram versus standard therapy in major depression A Markov process analysis comparing the cost effectiveness of maintenance therapy with citalopram versus standard therapy in major depression Nuijten M J, Hardens M, Souetre E Record Status This is a critical (...) population Patients with major depression. No other patients' characteristics were provided. Setting Primary care. The economic study was carried out in Germany. Dates to which data relate The date of clinical data was not specified. All costs were in 1993 Deutschmarks. Source of effectiveness data The clinical data regarding the treatment patterns and their associated transition probabilities (for the modelling) were obtained from the published literature and US clinical practice guidelines. Modelling

1995 NHS Economic Evaluation Database.

1806. A model to evaluate the cost-effectiveness of oral therapies in the management of patients with major depressive disorders

A model to evaluate the cost-effectiveness of oral therapies in the management of patients with major depressive disorders A model to evaluate the cost-effectiveness of oral therapies in the management of patients with major depressive disorders A model to evaluate the cost-effectiveness of oral therapies in the management of patients with major depressive disorders Einarson T R, Arikian S, Sweeney S, Doyle J Record Status This is a critical abstract of an economic evaluation that meets (...) the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Oral antidepressant therapies: venlafaxine, a serotonin norepinephrine reuptake inhibitor (SNRI); tricyclic antidepressants (TCAs); selective serotonin reuptake inhibitors (SSRIs); and heterocyclic antidepressants (HCAs)for patients with major depressive disorders

1995 NHS Economic Evaluation Database.

1807. Effects of rehabilitation exercise programmes on anxiety and depression in coronary patients: a meta-analysis

Effects of rehabilitation exercise programmes on anxiety and depression in coronary patients: a meta-analysis Effects of rehabilitation exercise programmes on anxiety and depression in coronary patients: a meta-analysis Effects of rehabilitation exercise programmes on anxiety and depression in coronary patients: a meta-analysis Kugler J, Seelbach H, Kruskemper G M Authors' objectives (1) To estimate the effect size of exercise treatment on anxiety and depression as compared with other (...) operation, were included. Outcomes assessed in the review Anxiety and depression were assessed. How were decisions on the relevance of primary studies made? Studies were included if: they provided treatment for coronary patients; patients were examined before and after the treatment for medical and work capacity; the exercise programme was designed to induce physical training effects; patients were only exposed to exercise treatment; studies combining exercise with other treatments were excluded

1994 DARE.

1808. Cost utility of maintenance treatment of recurrent depression with sertraline versus episodic treatment with dothiepin

Cost utility of maintenance treatment of recurrent depression with sertraline versus episodic treatment with dothiepin Cost utility of maintenance treatment of recurrent depression with sertraline versus episodic treatment with dothiepin Cost utility of maintenance treatment of recurrent depression with sertraline versus episodic treatment with dothiepin Hatziandreu E J, Brown R E, Revicki D A, Turner R, Martindale J, Levine S, Siegel J E Record Status This is a critical abstract of an economic (...) evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Selective serotonin reuptake inhibitors versus tricyclic antidepressants. Type of intervention Treatment. Economic study type Cost-utility analysis Study population Model of 2 hypothetical cohorts of 35 year old women suffering from depression

1994 NHS Economic Evaluation Database.

1809. Cost-effectiveness considerations for managed care systems: treating depression in primary care

Cost-effectiveness considerations for managed care systems: treating depression in primary care Cost-effectiveness considerations for managed care systems: treating depression in primary care Cost-effectiveness considerations for managed care systems: treating depression in primary care McFarland B H Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results (...) and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Primary care depression management using imipramine or paroxetine. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population Not stated. Setting The practice setting was primary care. The economic study was carried out in Oregon, US. Dates to which data relate Effectiveness data related to 1991. The dates to which resource data related

1994 NHS Economic Evaluation Database.

1810. The treatment of depression in primary care

The treatment of depression in primary care The treatment of depression in primary care The treatment of depression in primary care NHS Centre for Reviews and Dissemination Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation NHS Centre for Reviews and Dissemination. The treatment of depression in primary care. University of York. Effective (...) Health Care 1(5). 1993 Authors' objectives To assess which treatments are effective in the management of depression in primary care. Authors' conclusions Effective strategies to improve the detection and appropriateness of treatment of depression in primary care are available. The increasing use of the SSRI's as the routine first-line treatment in major depression may result in large increases in the NHS drug budget for antidepressants and should be carefully monitored. Further research is required

1993 Health Technology Assessment (HTA) Database.

1811. Edinburgh primary care depression study: treatment outcome, patient satisfaction, and cost after 16 weeks. Full Text available with Trip Pro

Edinburgh primary care depression study: treatment outcome, patient satisfaction, and cost after 16 weeks. To compare the clinical efficacy, patient satisfaction, and cost of three specialist treatments for depressive illness with routine care by general practitioners in primary care.Prospective, randomised allocation to amitriptyline prescribed by a psychiatrist, cognitive behaviour therapy from a clinical psychologist, counselling and case work by a social worker, or routine care by a general (...) practitioner.121 patients aged between 18 and 65 years suffering depressive illness (without psychotic features) meeting the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Third Edition for major depressive episode in 14 primary care practices in southern Edinburgh.Standard observer rating of depression at outset and after four and 16 weeks. Numbers of patients recovered at four and 16 weeks. Total length and cost of therapist contact. Structured evaluation of treatment by patients

1992 BMJ Controlled trial quality: uncertain

1812. Lithium treatment of depressed and nondepressed alcoholics. (Abstract)

Lithium treatment of depressed and nondepressed alcoholics. We assessed the efficacy of lithium carbonate in the treatment of 457 male alcoholics in a double-blind, placebo-controlled Department of Veterans Affairs Cooperative Study. Alcoholics either without depression or with a history of major depression, current major depression, or dysthymic disorder were studied. Two hundred eighty-six alcoholics without depression and 171 alcoholics with depression began the 52-week outpatient study; 172 (...) alcoholics (60.1%) without depression and 108 alcoholics (63.2%) with depression completed the study. Among both all alcoholics who began the study and a subgroup who completed the study, no significant differences between alcoholics who took lithium and those who took placebo were found for the following outcome measures:number of alcoholics abstinent, number of days of drinking, number of alcohol-related hospitalizations, changes in rating of severity of alcoholism, and change in severity of depression

1989 JAMA Controlled trial quality: uncertain

1813. Counselling in a general practice setting: controlled study of health visitor intervention in treatment of postnatal depression. Full Text available with Trip Pro

Counselling in a general practice setting: controlled study of health visitor intervention in treatment of postnatal depression. To determine whether counselling by health visitors is helpful in managing postnatal depression.Controlled, random order trial.Health centres in Edinburgh and Livingston.Sixty women identified as depressed by screening at six weeks post partum and by psychiatric interview at about 13 weeks post partum. Five women did not wish to participate, and a further five did (...) not complete the trial. Age, social and obstetric factors, and diagnosis were similar in women who completed the trial and those who withdrew.Eight weekly counselling visits by health visitors who had been given a short training in counselling for postnatal depression.Reduction of depression. MEASUREMENTS and main results--Standardised psychiatric interviews and a 10 point self report scale were used to identify depression before and after intervention. The psychiatrist was not told to which group women

1989 BMJ Controlled trial quality: uncertain

1814. Nortriptyline treatment of post-stroke depression: a double-blind study. (Abstract)

Nortriptyline treatment of post-stroke depression: a double-blind study. The efficacy of nortriptyline in the treatment of post-stroke depression was assessed by a double-blind study in thirty-four patients. Half of the patients had major depression. There was a significantly greater improvement in depression in patients treated with nortriptyline than in a similar group of placebo-treated patients. Depression was measured by the Hamilton depression scale, Zung depression scale, present state (...) examination, and an overall depression scale. Successfully treated patients had serum nortriptyline levels in the therapeutic range. Post-stroke depressions are common, severe, and longstanding, and the demonstrated efficacy of nortriptyline provides an important addition to the treatments available for stroke patients.

1984 Lancet Controlled trial quality: uncertain

1815. Comparison of alprazolam, imipramine, and placebo in the treatment of depression. (Abstract)

Comparison of alprazolam, imipramine, and placebo in the treatment of depression. Alprazolam is the first of the triazolobenzodiazepines to be studied in a large population of depressed patients. In a six-week, double-blind multicenter comparison of alprazolam, imipramine hydrochloride, and placebo in the treatment of 723 patients with depression, the two active drugs were statistically more effective than placebo. Alprazolam was at least as effective as imipramine in relieving depressive

1983 JAMA

1816. Double-blind controlled trail of electroconvulsive therapy (E.C.T.) and simulated E.C.T. in depressive illness. (Abstract)

Double-blind controlled trail of electroconvulsive therapy (E.C.T.) and simulated E.C.T. in depressive illness. 40 patients prescribed electroconvulsive therapy (E.C.T.) for treatment of a depressive illness were randomly allocated to two groups. One group had the first two E.C.T. treatments replaced by simulated E.C.T. on a double-blind basis. The results show that E.C.T. is significantly superior to simulated E.C.T. in the treatment of depressive illness.

1978 Lancet

1817. Drug treatment in depression. Antidepressant or tranquilizer? (Abstract)

Drug treatment in depression. Antidepressant or tranquilizer? 5340332 1967 10 02 2016 10 17 0098-7484 201 9 1967 Aug 28 JAMA JAMA Drug treatment in depression. Antidepressant or tranquilizer? 675-81 Rickels K K Raab E E DeSilverio R R Etemad B B eng Clinical Trial Comparative Study Journal Article Randomized Controlled Trial United States JAMA 7501160 0098-7484 0 Antidepressive Agents 0 Placebos 9I7LNY769Q Meprobamate AIM IM Adult Antidepressive Agents therapeutic use Anxiety Disorders drug (...) therapy Clinical Trials as Topic Depression drug therapy Female Humans Male Meprobamate therapeutic use Placebos 1967 8 28 1967 8 28 0 1 1967 8 28 0 0 ppublish 5340332

1967 JAMA Controlled trial quality: uncertain