Latest & greatest articles for depression

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Top results for depression

1. Depression in children

Depression in children Depression in children - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Depression in children Last reviewed: October 2018 Last updated: November 2018 Summary Characterised by sad or irritable mood, anhedonia, decreased capacity to have fun, decreased self-esteem, sleep disturbance, social withdrawal or impaired social relationships, and impaired school performance. One of the most common (...) paediatric psychiatric disorders, especially among girls during adolescence. At-risk children should be screened for depression. It is crucial to make an accurate diagnosis, based on a comprehensive assessment and review of the history, with input from multiple sources. The safety of the child and others, and the duration and severity of depression, need to be evaluated carefully to help determine the appropriate level of care and treatment modality. Treatment is typically with active monitoring

BMJ Best Practice2018

2. Overview of depression

Overview of depression Overview of depression - Summary of relevant conditions | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Overview of depression Last reviewed: October 2018 Last updated: November 2018 Introduction Depression is a mental state characterised by persistent low mood, loss of interest and enjoyment in everyday activities, neurovegetative disturbance, and reduced energy, causing varying levels of social and occupational dysfunction (...) . Depressive disorders are common in people of all ages and may be classified depending on the duration, severity, and number of symptoms, and the degree of functional impairment. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed. (DSM-5). Washington, DC: American Psychiatric Publishing; 2013. In bipolar disorder, a manic episode may have been preceded by and may be followed by hypomanic or major depressive episodes. American Psychiatric Association. Diagnostic

BMJ Best Practice2018

3. Guided online interventions can help people recover from depression

Guided online interventions can help people recover from depression Guided online interventions can help people recover from depression Dissemination Centre Discover Portal NIHR DC Discover Guided online interventions can help people recover from depression Published on 6 November 2018 doi: Internet-based interventions combined with remote professional support can improve outcomes for people with depression. Those receiving the intervention show better initial response to treatment and higher (...) recovery rates compared with control groups who are either waiting for treatment or receiving less support. This meta-analysis shows people using guided internet therapy are over twice as likely to respond to treatment and achieve remission. This finding reinforces current NICE guidance which recommends this type of approach for mild to moderate depression. This type of treatment has the potential to reach more people than face to face therapy and provides more support than wholly self-directed

NIHR Dissemination Centre2018

4. Depression.

Depression. Major depression is a common illness that severely limits psychosocial functioning and diminishes quality of life. In 2008, WHO ranked major depression as the third cause of burden of disease worldwide and projected that the disease will rank first by 2030. 1 In practice, its detection, diagnosis, and management often pose challenges for clinicians because of its various presentations, unpredictable course and prognosis, and variable response to treatment.

Lancet2018

6. Acceptability of the Fitbit in behavioural activation therapy for depression: a qualitative study

Acceptability of the Fitbit in behavioural activation therapy for depression: a qualitative study Acceptability of the Fitbit in behavioural activation therapy for depression: a qualitative study | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Acceptability of the Fitbit in behavioural activation therapy for depression: a qualitative study Article Text Original article Acceptability of the Fitbit in behavioural activation therapy

Evidence-Based Mental Health2018

7. Depression increases the risk of inflammatory bowel disease, which may be mitigated by the use of antidepressants in the treatment of depression

Depression increases the risk of inflammatory bowel disease, which may be mitigated by the use of antidepressants in the treatment of depression 30337374 2018 10 19 1468-3288 2018 Oct 18 Gut Gut Depression increases the risk of inflammatory bowel disease, which may be mitigated by the use of antidepressants in the treatment of depression. gutjnl-2018-317182 10.1136/gutjnl-2018-317182 Depression is associated with IBD, but the effect of antidepressants on IBD has been sparsely studied. We (...) assessed the impact of depression and antidepressant therapies on the development of IBD. The Health Improvement Network (THIN) was used to identify a cohort of patients with new-onset depression from 1986 to 2012. THIN patients who did not meet the defining criteria for depression were part of the referent group. The outcome was incident Crohn's disease (CD) or ulcerative colitis (UC). Cox proportional hazards modelling was performed to evaluate the rate of Crohn's disease or UC development among

EvidenceUpdates2018

8. Indicated preventive interventions for depression in children and adolescents: A meta-analysis and meta-regression

Indicated preventive interventions for depression in children and adolescents: A meta-analysis and meta-regression 30287331 2018 11 16 1096-0260 118 2018 Oct 02 Preventive medicine Prev Med Indicated preventive interventions for depression in children and adolescents: A meta-analysis and meta-regression. 7-15 S0091-7435(18)30299-8 10.1016/j.ypmed.2018.09.021 Depression contributes about 2% to the global burden of disease. A first onset of depressive disorder or subsyndromal depressive symptoms (...) is common in adolescence, indicating that early prevention is a priority. However, trials of preventive interventions for depression in youths show conflicting results. This systematic review and meta-analysis investigated the effectiveness of group-based cognitive behavioral therapy (GB-CBT) as a preventive intervention targeting subsyndromal depression in children and adolescents. In addition, the impact of different covariates (type of comparator and use of booster sessions) was assessed. Relevant

EvidenceUpdates2018

9. Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR).

Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR). OBJECTIVE: To investigate the effectiveness of combining mirtazapine with serotonin-noradrenaline reuptake inhibitor (SNRI) or selective serotonin reuptake inhibitor (SSRI) antidepressants for treatment resistant depression in primary care. DESIGN: Two parallel group multicentre phase III randomised placebo controlled trial. SETTING: 106 general practices (...) in four UK sites; Bristol, Exeter, Hull, and Keele/North Staffs, August 2013 to October 2015. PARTICIPANTS: 480 adults aged 18 or more years who scored 14 or more on the Beck depression inventory, second revision, fulfilled ICD-10 (international classification of diseases, 10th revision) criteria for depression, and had used an SSRI or SNRI for at least six weeks but were still depressed. 241 were randomised to mirtazapine and 239 to placebo, both given in addition to usual SSRI or SNRI treatment

BMJ2018

10. Aerobic exercise moderately reduces depressive symptoms in new mothers

Aerobic exercise moderately reduces depressive symptoms in new mothers Signal - Aerobic exercise moderately reduces depressive symptoms in new mothers Dissemination Centre Discover Portal NIHR DC Discover Aerobic exercise moderately reduces depressive symptoms in new mothers Published on 21 November 2017 For women who have had a baby in the past year, doing aerobic exercise can reduce the level of depressive symptoms they experience. This NIHR funded review of 13 studies showed that involving (...) new mothers in group exercise programmes, or advising them on an exercise of their choice, reduced depressive symptoms compared with usual care. The effect was moderate but significant. Examples of exercise were pram walks, with dietary advice from peers in some studies. The benefits were shown whether or not the mothers had postnatal depression. This evidence does have some limitations regarding its quality but is the best research currently available. This review should give additional

NIHR Dissemination Centre2018

11. A primary care intervention helps older people with depression

A primary care intervention helps older people with depression Signal - A primary care intervention helps older people with depression Dissemination Centre Discover Portal NIHR DC Discover A primary care intervention helps older people with depression Published on 23 January 2018 Enhanced case management (also called collaborative care) added to primary care reduced symptoms in people with clinical depression, compared with usual primary care. The benefit was similar to other depression (...) rolled-out to older people not using the Improving Access to Psychological Therapies programme. It is possible that greater treatment duration of the number of sessions might lead to longer-term impacts. These results have contributed to the draft NICE depression guideline out for consultation in 2017. Those with physical health and mobility problems and other barriers to using services may especially benefit. Share your views on the research. Why was this study needed? About one in seven people over

NIHR Dissemination Centre2018

12. Collaborative care can be moderately effective at treating depression regardless of physical health status

Collaborative care can be moderately effective at treating depression regardless of physical health status Signal - Collaborative care can be moderately effective at treating depression regardless of physical health status Dissemination Centre Discover Portal NIHR DC Discover Collaborative care can be moderately effective at treating depression regardless of physical health status Published on 21 February 2017 Collaborative care can be moderately effective at treating depression compared (...) to usual care, whether or not people also have a long-term condition such as cancer or heart disease. Collaboration was provided by a case manager in primary care who was not a mental health professional. They coordinated a treatment plan with input from a GP and mental health professional. It is currently only recommended for people with depression and a long-term physical condition as prior to this review there was only consistent evidence of its effectiveness for people with both. This NIHR-funded

NIHR Dissemination Centre2018

13. Three psychological therapies are effective for adolescent depression

Three psychological therapies are effective for adolescent depression Signal - Three psychological therapies are effective for adolescent depression Dissemination Centre Discover Portal NIHR DC Discover Three psychological therapies are effective for adolescent depression Published on 4 July 2017 For adolescents with unipolar major depression, there was no difference in self-reported depressive symptoms or cost-effectiveness after 18 months for cognitive behavioural therapy (CBT), short-term (...) psychoanalytic psychotherapy and brief psychological intervention. This was a large NIHR funded trial of three evidence-based psychological therapies often used in the NHS alongside medication or without it. Teenagers from various sites in the UK were randomly allocated to one of the three therapy types and some also given antidepressants if indicated. Uptake and attendance proved difficult, which may be an element for further research. Around a quarter had indication of unipolar major depression 18 months

NIHR Dissemination Centre2018

14. Overseas models of specialist support for primary care physicians in managing depression may not be transferrable to the UK health system

Overseas models of specialist support for primary care physicians in managing depression may not be transferrable to the UK health system Signal - Overseas models of specialist support for primary care physicians in managing depression may not be transferrable to the UK health system Dissemination Centre Discover Portal NIHR DC Discover Overseas models of specialist support for primary care physicians in managing depression may not be transferrable to the UK health system Published on 11 (...) or may not have direct contact with the patient. Half of the trials were from the USA, where specialist care is normal for illness of all severity, and only one from the UK. Relevance to the NHS is likely to be limited. Most studies were in people with depression with limited evidence available for other mental health conditions. Evidence was strongest for an effect on adherence to treatment, with few studies examining effects on patient mental health outcomes. The review did not examine whether

NIHR Dissemination Centre2018

15. Antidepressants and talking therapies offer similar benefits for new-onset major depression

Antidepressants and talking therapies offer similar benefits for new-onset major depression Signal - Antidepressants and talking therapies offer similar benefits for new-onset major depression Dissemination Centre Discover Portal NIHR DC Discover Antidepressants and talking therapies offer similar benefits for new-onset major depression Published on 23 March 2016 This review found no difference in effectiveness or drop-out rates between antidepressants and cognitive (...) behavioural therapy for adults recently diagnosed with major depressive disorder. Both treatments should be offered, as recommended by NICE, either alone or possibly in combination, and the final decision will rely heavily on the patient’s preference. The challenge for talking therapies in the NHS has long been a lack of capacity. However, the Improving Access to Psychological Therapies programme has in the last few years provided thousands of trained therapists who can be accessed through GPs and in some cases directly

NIHR Dissemination Centre2018

16. Collaborative mental health care in the NHS has small but meaningful benefits for people with depression

Collaborative mental health care in the NHS has small but meaningful benefits for people with depression Signal - Collaborative mental health care in the NHS has small but meaningful benefits for people with depression Dissemination Centre Discover Portal NIHR DC Discover Collaborative mental health care in the NHS has small but meaningful benefits for people with depression Published on 31 May 2016 Collaborative care, that places a care manager in primary care to deliver treatment (...) and coordinate care between GPs and specialists, improved recovery of people with moderate to severe depression. Primary responsibility for prescribing remained with the GP. This large trial found that improvements were modest, but were similar to those found in an evaluation of the Improving Access to Psychological Therapies programme. The collaborative care model was cost-effective too. Collaborative care cost on average £272.50 per participant and had a cost per quality-adjusted life year (QALY

NIHR Dissemination Centre2018

17. One type of drug for depression during pregnancy may be linked to a small increase in pre-term births

One type of drug for depression during pregnancy may be linked to a small increase in pre-term births Signal - One type of drug for depression during pregnancy may be linked to a small increase in pre-term births Dissemination Centre Discover Portal NIHR DC Discover One type of drug for depression during pregnancy may be linked to a small increase in pre-term births Published on 9 August 2016 Women who are depressed during pregnancy and who take selective serotonin inhibitors (SSRIs) may be (...) more likely to have a pre-term birth than those who do not take SSRIs. Pre-term birth occurred in 6.8% of women with depression during pregnancy treated with SSRIs compared to 5.8% of depressed women who were treated with talking therapies alone. However, because this is a review of observational (cohort) studies rather than randomised controlled trials it is not possible to say that SSRIs cause pre-term birth. For example, it is possible that women who had worse depression were more likely

NIHR Dissemination Centre2018

18. Two simple questions help GPs rule out depression

Two simple questions help GPs rule out depression Signal - Two simple questions help GPs rule out depression Dissemination Centre Discover Portal NIHR DC Discover Two simple questions help GPs rule out depression Published on 23 March 2016 The Whooley questions are useful for ruling out depression in that few people who answer no to both questions are depressed according to a ‘gold standard’ diagnostic interview. A positive screen is indicated by the person answering “yes” to one or both (...) of the Whooley questions and for these people the diagnostic interview will still be necessary to diagnose the condition. The two simple questions are; 1) have you felt down or depressed or hopeless? and 2) have you been bothered by little interest or pleasure in doing things? - in the past month. The questions are already recommended by NICE to identify people who may be at higher risk of depression, prior to further assessment. These people include those with long-term conditions and women before or after

NIHR Dissemination Centre2018

19. Depression and anxiety common in people with heart disease

Depression and anxiety common in people with heart disease Signal - Depression and anxiety common in people with heart disease Dissemination Centre Discover Portal NIHR DC Discover Depression and anxiety common in people with heart disease Published on 28 June 2016 This multi-part NIHR study found that depression and anxiety were more common in people with coronary heart disease, than the general population. Anxiety increased people’s risk of a future heart attack. The people included (...) in the study were generally older, white males, so the findings may not apply to everyone. Patients considered a nurse-led intervention to personalise care was acceptable. The intervention included optimising medicines and facilitating referrals for psychological support. When asked, people with depression and coronary heart disease generally favoured non-medical treatments. These findings provide an insight into the scale of depression and anxiety amongst people with coronary heart disease. Overall costs

NIHR Dissemination Centre2018

20. Online cognitive behavioural therapy is no more effective than usual GP care for people with depression

Online cognitive behavioural therapy is no more effective than usual GP care for people with depression Signal - Online cognitive behavioural therapy is no more effective than usual GP care for people with depression Dissemination Centre Discover Portal NIHR DC Discover Online cognitive behavioural therapy is no more effective than usual GP care for people with depression Published on 9 February 2016 Computerised cognitive behavioural therapy (CBT) in addition to usual GP care was no more (...) effective than usual GP care alone at four months or at 24 months. It was also not a popular treatment for patients with mild to moderate depression who typically only used the programme once or twice. Indeed, more than four out of five patients did not complete the course. Depression affects large numbers of people in the UK. Other research shows that CBT is effective in treating depression, but it is expensive to provide and people sometimes have to wait for treatment due to limited numbers

NIHR Dissemination Centre2018