Latest & greatest articles for delirium

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Top results for delirium

141. Cholinesterase inhibitors for delirium.

Cholinesterase inhibitors for delirium. BACKGROUND: Delirium is now the preferred term to describe acute confusional states. It is experienced by 10 to 30% of all hospital inpatients. Delirium is potentially reversible and is related to several adverse outcomes, including increased hospital length of stay, poor functional status, persistent cognitive impairment, need for institutional care and probably mortality. Disruption of the cholinergic system has been proposed as a key mechanism (...) of delirium. Cholinesterase inhibitors enhance the cholinergic system and there have been reports that they might be beneficial in treating delirium. OBJECTIVES: To assess the efficacy and safety of cholinesterase inhibitors in the treatment of delirium. SEARCH STRATEGY: The Cochrane Dementia and Cognitive Improvement Group's Register of Clinical Trials (which includes records from MEDLINE, EMBASE, PsycINFO, CINAHL, CENTRAL, LILACS and other databases) was searched for relevant randomised controlled

Cochrane2008

142. Drug treatment of delirium: past, present and future

Drug treatment of delirium: past, present and future Drug treatment of delirium: past, present and future Drug treatment of delirium: past, present and future Bourne RS, Tahir TA, Borthwick M, Sampson EL CRD summary This review concluded that the efficacy rates between typical and atypical antipsychotics for the treatment of delirium were similar, but the latter was associated with fewer extrapyramidal adverse effects. In view of a lack of details on study quality and other methodological (...) concerns in the review methods, the authors' conclusions may not be reliable. Authors' objectives To assess the efficacy and safety of drug therapy for the treatment or prevention of delirium. Searching The following databases were searched for English language studies from 1967 to March 2008: MEDLINE, EMBASE, PsycINFO and the Cochrane Library. Search terms were reported. Conference proceedings from Academy of Psychosomatic Medicine, European Delirium Association and critical care (European Society

DARE.2008

143. Adjunctive haloperidol prophylaxis reduces postoperative delirium severity and duration in at-risk elderly patients

Adjunctive haloperidol prophylaxis reduces postoperative delirium severity and duration in at-risk elderly patients Adjunctive haloperidol prophylaxis reduces postoperative delirium severity and duration in at-risk elderly patients Adjunctive haloperidol prophylaxis reduces postoperative delirium severity and duration in at-risk elderly patients Schrader S L, Wellik K E, Demaerschalk B M, Caselli R J, Woodruff B K, Wingerchuk D M CRD summary The review concluded that adjunctive low-dose (...) haloperidol prophylaxis reduced severity and duration of delirium and length of hospital stay in elderly at-risk patients. Further research needed to determine: an optimal pharmacological approach; combination with non-pharmacological strategies; and generalisability. The paucity of evidence and methodological uncertainties made the authors' conclusion seem overstated and it may not be reliable. Authors' objectives To determine whether antipsychotic drug prophylaxis reduces the incidence and severity

DARE.2008

144. WITHDRAWN: Multidisciplinary team interventions for delirium in patients with chronic cognitive impairment.

WITHDRAWN: Multidisciplinary team interventions for delirium in patients with chronic cognitive impairment. BACKGROUND: Delirium is common in hospitalized elderly people. Delirium may affect 60% of frail elderly people in hospital. Among the cognitively impaired, 45% have been found to develop delirium and these patients have longer lengths of hospital stay and a higher rate of complications which, with other factors, increase costs of care. The management of delirium has commonly been (...) multifaceted, the primary emphasis has to be on the diagnosis and therapy of precipitating factors, but as these may not be immediately resolved, symptomatic and supportive care are also of major importance. OBJECTIVES: The objective of this review is to assess the available evidence for the effectiveness, if any, of multidisciplinary team interventions in the coordinated care of elderly patients with delirium superimposed on an underlying chronic cognitive impairment in comparison with usual care. SEARCH

Cochrane2007

145. Interventions for preventing delirium in hospitalised patients.

Interventions for preventing delirium in hospitalised patients. BACKGROUND: Delirium is a common mental disorder with serious adverse outcomes in hospitalised patients. It is associated with increases in mortality, physical morbidity, length of hospital stay, institutionalisation and costs to healthcare providers. A range of risk factors has been implicated in its aetiology, including aspects of the routine care and environment in hospitals. Prevention of delirium is clearly desirable from (...) patients' and carers' perspectives, and to reduce hospital costs. Yet it is currently unclear whether interventions for prevention of delirium are effective, whether they can be successfully delivered in all environments, and whether different interventions are necessary for different groups of patients. OBJECTIVES: Our primary objective was to determine the effectiveness of interventions designed to prevent delirium in hospitalised patients. We also aimed to highlight the quality and quantity

Cochrane2007

146. Antipsychotics for delirium.

Antipsychotics for delirium. BACKGROUND: Delirium occurs in up to 30% of hospitalised patients and is associated with prolonged hospital stay and increased morbidity and mortality. Recently published reports have suggested that the standard drug for delirium, haloperidol, a typical antipsychotic that may cause adverse extrapyramidal symptoms among patients, may be replaced by atypical antipsychotics such as risperidone, olanzapine or quetiapine, that are as effective as haloperidol (...) in controlling delirium, but that have a lower incidence of extrapyramidal adverse effects. OBJECTIVES: To compare the efficacy and incidence of adverse effects of haloperidol with risperidone, olanzapine, and quetiapine in the treatment of delirium. SEARCH STRATEGY: The trials were identified from a search of the Specialized Register of the Cochrane Dementia and Cognitive Improvement Group on 7 August 2006 using the search terms:haloperidol or haldol or risperidone or risperdal* or quetiapine or seroquel

Cochrane2007

147. Antipsychotics in the treatment of delirium: a systematic review

Antipsychotics in the treatment of delirium: a systematic review Antipsychotics in the treatment of delirium: a systematic review Antipsychotics in the treatment of delirium: a systematic review Seitz D P, Gill S S, van Zyl L T CRD summary The authors assessed the efficacy and safety of antipsychotic drugs for treating delirium. They concluded that the use of some low-dose, short-term antipsychotic drugs is supported only by limited evidence, and that further research is required. The authors (...) ’ conclusions follow from the evidence presented and appear reliable. Authors' objectives To evaluate the efficacy and safety of antipsychotic drugs for treating the symptoms of delirium. Searching MEDLINE (January 1980 to July 2005) and the Cochrane Library were searched for articles published in English; the search terms were reported. The reference lists of retrieved articles were checked. Study selection Study designs of evaluations included in the review Prospective studies that used standardised

DARE.2007

148. Watching a video of themselves experiencing delirium tremens reduces relapse rates for up to three months in people with severe alcohol dependence

Watching a video of themselves experiencing delirium tremens reduces relapse rates for up to three months in people with severe alcohol dependence Watching a video of themselves experiencing delirium tremens reduces relapse rates for up to three months in people with severe alcohol dependence | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers (...) of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Watching a video of themselves experiencing delirium tremens reduces relapse rates for up to three months in people with severe alcohol dependence Article Text Therapeutics Watching a video of themselves experiencing

Evidence-Based Mental Health2007

149. The incidence of delirium in older people with a mood disorder is similar with lithium and valproate

The incidence of delirium in older people with a mood disorder is similar with lithium and valproate The incidence of delirium in older people with a mood disorder is similar with lithium and valproate | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search (...) for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here The incidence of delirium in older people with a mood disorder is similar with lithium and valproate Article Text Prognosis The incidence of delirium in older people with a mood disorder is similar with lithium and valproate Free James A Bourgeois , OD MD Statistics from Altmetric.com No Altmetric

Evidence-Based Mental Health2006

150. A decrease of 2 points on the Mini-Mental State Examination was the best determinant of delirium in elderly patients admitted to hospital

A decrease of 2 points on the Mini-Mental State Examination was the best determinant of delirium in elderly patients admitted to hospital A decrease of ⩾2 points on the Mini-Mental State Examination was the best determinant of delirium in elderly patients admitted to hospital | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts (...) Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here A decrease of ⩾2 points on the Mini-Mental State Examination was the best determinant of delirium in elderly patients admitted to hospital Article Text Diagnosis A decrease of ⩾2 points on the Mini-Mental State Examination was the best

Evidence-Based Medicine (Requires free registration)2006

151. Review: sedative hypnotic agents reduce mortality and duration of delirium in the alcohol withdrawal syndrome

Review: sedative hypnotic agents reduce mortality and duration of delirium in the alcohol withdrawal syndrome Review: sedative hypnotic agents reduce mortality and duration of delirium in the alcohol withdrawal syndrome | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search (...) for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: sedative hypnotic agents reduce mortality and duration of delirium in the alcohol withdrawal syndrome Article Text Therapeutics Review: sedative hypnotic agents reduce mortality and duration of delirium in the alcohol withdrawal syndrome Statistics from Altmetric.com No Altmetric data

Evidence-Based Medicine (Requires free registration)2006

152. Systematic review of antipsychotics for the treatment of hospital-associated delirium in medically or surgically ill patients

Systematic review of antipsychotics for the treatment of hospital-associated delirium in medically or surgically ill patients Systematic review of antipsychotics for the treatment of hospital-associated delirium in medically or surgically ill patients Systematic review of antipsychotics for the treatment of hospital-associated delirium in medically or surgically ill patients Lacasse H, Perreault M M, Williamson D R CRD summary The authors concluded that antipsychotic drugs are an effective (...) and safe treatment of delirium in medically or surgically ill patients. Recommendations for specific agents are limited by the quality and quantity of the available data. The authors’ conclusions reflect the evidence available but the included studies were small and had serious flaws, therefore these conclusions may not be reliable. Authors' objectives To evaluate the efficacy and safety of antipsychotic drugs in the treatment of delirium in medically or surgically ill patients. Searching MEDLINE (from

DARE.2006

153. The role of postoperative analgesia in delirium and cognitive decline in elderly patients: a systematic review

The role of postoperative analgesia in delirium and cognitive decline in elderly patients: a systematic review The role of postoperative analgesia in delirium and cognitive decline in elderly patients: a systematic review The role of postoperative analgesia in delirium and cognitive decline in elderly patients: a systematic review Fong H K, Sands L P, Leung J M CRD summary This review assessed the effects of opioid analgesics on postoperative delirium and cognitive decline in elderly patients (...) . The authors reported an increased risk of postoperative delirium associated with meperidine, but no apparent differences associated with the mode of drug delivery. Given that studies used different outcome measures and definitions, and lacked statistical power, the authors' findings should be interpreted with caution. Authors' objectives To determine the effects of opioid analgesics on post-operative delirium and cognitive decline in elderly patients. Searching CINAHL and PubMed were searched from 1966

DARE.2006

154. Evidence-based clinical update: general anesthesia and the risk of delirium and postoperative cognitive dysfunction

Evidence-based clinical update: general anesthesia and the risk of delirium and postoperative cognitive dysfunction Evidence-based clinical update: general anesthesia and the risk of delirium and postoperative cognitive dysfunction Evidence-based clinical update: general anesthesia and the risk of delirium and postoperative cognitive dysfunction Bryson G L, Wyand A CRD summary This review found no significant difference in the incidence of delirium or post-operative cognitive dysfunction (...) between patients receiving general anaesthesia and those receiving regional anaesthesia. Given the small size and poor quality of the included studies, the authors conclusions would appear valid. Authors' objectives To assess the risk of delirium and post-operative cognitive dysfunction (POCD) associated with general versus regional anaesthesia. Searching MEDLINE was searched from 1966 to June 2005; the search terms were reported. The reference lists of eligible studies were screened for additional

DARE.2006

155. Multicomponent intervention strategies for managing delirium in hospitalized older people: systematic review

Multicomponent intervention strategies for managing delirium in hospitalized older people: systematic review Multicomponent intervention strategies for managing delirium in hospitalized older people: systematic review Multicomponent intervention strategies for managing delirium in hospitalized older people: systematic review Milisen K, Lemiengre J, Braes T, Foreman M D CRD summary This review assessed the effectiveness of multi-component intervention strategies for preventing and treating (...) delirium in hospitalised elderly people. The authors concluded that most interventions had the potential to reduce the duration and severity of delirium. However, these conclusions do not appear to be strongly supported by the data presented and a more cautious conclusion may have been more appropriate. Authors' objectives To describe the characteristics and assess the effectiveness of multi-component intervention strategies for preventing and treating delirium in hospitalised elderly people. Searching

DARE.2005

156. Caregiving strategies for older adults with delirium, dementia and depression.

Caregiving strategies for older adults with delirium, dementia and depression. Caregiving strategies for older adults with delirium, dementia and depression. | National Guideline Clearinghouse Search Sign In Username or Email * Password * Remember Me Don't have an account? Guideline Summary NGC:003848 This guideline summary has been replaced by an updated version. Please update your bookmarks. View the updated summary: NGC:008381 View all updated summaries in the . About NGC Guideline Summaries

Registered Nurses' Association of Ontario2004

157. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit.

Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. CONTEXT: In the intensive care unit (ICU), delirium is a common yet underdiagnosed form of organ dysfunction, and its contribution to patient outcomes is unclear. OBJECTIVE: To determine if delirium is an independent predictor of clinical outcomes, including 6-month mortality and length of stay among ICU patients receiving mechanical ventilation. DESIGN, SETTING, AND PARTICIPANTS: Prospective (...) cohort study enrolling 275 consecutive mechanically ventilated patients admitted to adult medical and coronary ICUs of a US university-based medical center between February 2000 and May 2001. Patients were followed up for development of delirium over 2158 ICU days using the Confusion Assessment Method for the ICU and the Richmond Agitation-Sedation Scale. MAIN OUTCOME MEASURES: Primary outcomes included 6-month mortality, overall hospital length of stay, and length of stay in the post-ICU period

JAMA2004

159. Multidisciplinary team interventions for delirium in patients with chronic cognitive impairment.

Multidisciplinary team interventions for delirium in patients with chronic cognitive impairment. BACKGROUND: Delirium is common in hospitalized elderly people. Delirium may affect 60% of frail elderly people in hospital. Among the cognitively impaired, 45% have been found to develop delirium and these patients have longer lengths of hospital stay and a higher rate of complications which, with other factors, increase costs of care. The management of delirium has commonly been multifaceted (...) , the primary emphasis has to be on the diagnosis and therapy of precipitating factors, but as these may not be immediately resolved, symptomatic and supportive care are also of major importance. OBJECTIVES: The objective of this review is to assess the available evidence for the effectiveness, if any, of multidisciplinary team interventions in the coordinated care of elderly patients with delirium superimposed on an underlying chronic cognitive impairment in comparison with usual care. SEARCH STRATEGY

Cochrane2004

160. Drug therapy for delirium in terminally ill patients.

Drug therapy for delirium in terminally ill patients. BACKGROUND: Delirium is a common disorder that often complicates treatment in patients with life-limiting disease. Delirium is described using a variety of terms such as agitation, acute confusional states, encephalopathy, organic mental disorders, and terminal restlessness. Delirium may arise from any number of causes, and treatment should be directed at addressing these causes. In cases where this is not possible, or does not prove (...) successful, the use of drug therapy may become necessary. OBJECTIVES: The primary objective of this review was to identify and evaluate studies examining medications used to treat patients suffering from delirium during the terminal phases of disease. SEARCH STRATEGY: We searched the following sources: MEDLINE (1966 to July 2003), EMBASE 1980 to July 2003), CINAHL (1982 to July 2003), PSYCH LIT (1974 to July 2003), PSYCHINFO (1990 to July 2003) and the Cochrane Library Volume 2, 2003) for literature

Cochrane2004