Latest & greatest articles for delirium

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on delirium or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on delirium and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for delirium

61. Cognitive Reserve and Postoperative Delirium in Older Adults

Cognitive Reserve and Postoperative Delirium in Older Adults 27321616 2016 06 20 2017 02 20 1532-5415 64 6 2016 Jun Journal of the American Geriatrics Society J Am Geriatr Soc Cognitive Reserve and Postoperative Delirium in Older Adults. 1341-6 10.1111/jgs.14130 To examine the role of cognitive reserve in reducing delirium incidence and severity in older adults undergoing surgery. Prospective cohort study. Hospital. Older adults (mean age 71.2, 65% women) undergoing elective orthopedic surgery (...) (N = 142). Incidence (Confusion Assessment Method) and severity (Memorial Delirium Assessment Scale) of postoperative delirium were the primary outcomes. Predictors included early- (literacy) and late-life (cognitive activities) proxies for cognitive reserve. Forty-five participants (32%) developed delirium. Greater participation in cognitive activity was associated with lower incidence (odds ratio = 0.92 corresponding to increase of 1 activity per week, 95% confidence interval (CI) = 0.86-0.98

EvidenceUpdates2016 Full Text: Link to full Text with Trip Pro

62. Abnormal Mini-Cog Is Associated with Higher Risk of Complications and Delirium in Geriatric Patients with Fracture

Abnormal Mini-Cog Is Associated with Higher Risk of Complications and Delirium in Geriatric Patients with Fracture 27147687 2016 05 05 2017 04 06 2017 04 06 1535-1386 98 9 2016 May 04 The Journal of bone and joint surgery. American volume J Bone Joint Surg Am Abnormal Mini-Cog Is Associated with Higher Risk of Complications and Delirium in Geriatric Patients with Fracture. 742-50 10.2106/JBJS.15.00859 The Mini-Cog test is a validated and simple tool to screen for dementia. The purpose (...) was 28.6%. Patients with an abnormal Mini-Cog test or those unable to complete the test had significantly higher odds of in-hospital complications (2.16 and 2.27, respectively) compared with patients with a normal Mini-Cog test (p < 0.001). Delirium was significantly increased in patients with an abnormal Mini-Cog test (odds ratio, 3.22; p = 0.001). The all-cause, one-year mortality rate after fracture in our population was 18.1%. Adjusted for age, sex, comorbidity, and fracture type, only the patients

EvidenceUpdates2016

63. Predicting delirium after hip fracture with a 2-min cognitive screen: prospective cohort study

Predicting delirium after hip fracture with a 2-min cognitive screen: prospective cohort study 27189725 2016 09 20 2016 09 20 1468-2834 45 5 2016 Sep Age and ageing Age Ageing Predicting delirium after hip fracture with a 2-min cognitive screen: prospective cohort study. 713-7 10.1093/ageing/afw084 although the importance of identifying hip fracture patients with high risk for delirium has been well established, considerable controversy exists over the choice of the screening tool. The most (...) commonly used cognitive screeners take an excessive amount of time and include drawing tasks that can be troublesome for individuals with hip fracture who are invariably lying in bed. to evaluate the properties of the 10-point Cognitive Screener (10-CS), a 2-min bedside tool, for predicting delirium in older adults with hip fracture. prospective cohort study. a tertiary referral hospital in São Paulo, Brazil. non-delirious older adults with hip fracture (n = 147). the 10-CS was administered

EvidenceUpdates2016 Full Text: Link to full Text with Trip Pro

64. Utility of the PRE-DELIRIC delirium prediction model in a Scottish ICU cohort

Utility of the PRE-DELIRIC delirium prediction model in a Scottish ICU cohort 28979492 2018 11 13 1751-1437 17 3 2016 Aug Journal of the Intensive Care Society J Intensive Care Soc Utility of the PRE-DELIRIC delirium prediction model in a Scottish ICU cohort. 202-206 10.1177/1751143716638373 The PREdiction of DELIRium for Intensive Care (PRE-DELIRIC) model reliably predicts at 24 h the development of delirium during intensive care admission. However, the model does not take account of alcohol (...) misuse, which has a high prevalence in Scottish intensive care patients. We used the PRE-DELIRIC model to calculate the risk of delirium for patients in our ICU from May to July 2013. These patients were screened for delirium on each day of their ICU stay using the Confusion Assessment Method for ICU (CAM-ICU). Outcomes were ascertained from the national ICU database. In the 39 patients screened daily, the risk of delirium given by the PRE-DELIRIC model was positively associated with prevalence

Journal of the Intensive Care Society2016 Full Text: Link to full Text with Trip Pro

65. Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial.

Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial. 26975647 2016 04 26 2016 05 09 2016 10 17 1538-3598 315 14 2016 Apr 12 JAMA JAMA Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial. 1460-8 10.1001/jama.2016.2707 Effective therapy has not been established for patients with agitated delirium receiving mechanical (...) ventilation. To determine the effectiveness of dexmedetomidine when added to standard care in patients with agitated delirium receiving mechanical ventilation. The Dexmedetomidine to Lessen ICU Agitation (DahLIA) study was a double-blind, placebo-controlled, parallel-group randomized clinical trial involving 74 adult patients in whom extubation was considered inappropriate because of the severity of agitation and delirium. The study was conducted at 15 intensive care units in Australia and New Zealand from

JAMA2016 Full Text: Link to full Text with Trip Pro

66. Treatment of Older Adults with Insomnia, Agitation, or Delirium with Benzodiazepines: Clinical Effectiveness and Guidelines

Treatment of Older Adults with Insomnia, Agitation, or Delirium with Benzodiazepines: Clinical Effectiveness and Guidelines Treatment of Older Adults with Insomnia, Agitation, or Delirium with Benzodiazepines: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Treatment of Older Adults with Insomnia, Agitation, or Delirium with Benzodiazepines: Clinical Effectiveness and Guidelines Treatment of Older Adults with Insomnia, Agitation, or Delirium with Benzodiazepines (...) : Clinical Effectiveness and Guidelines Published on: January 14, 2016 Project Number: RC0744-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of the treatment of older adults with insomnia, agitation, or delirium with benzodiazepines or other sedative hypnotic agents? What are the evidence-based guidelines for the treatment of older adults with insomnia, agitation, or delirium with benzodiazepines or other

Canadian Agency for Drugs and Technologies in Health - Rapid Review2016

67. Routine use of antipsychotics to prevent or treat delirium is not recommended

Routine use of antipsychotics to prevent or treat delirium is not recommended Routine use of antipsychotics to prevent or treat delirium is not recommended | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log (...) in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Routine use of antipsychotics to prevent or treat delirium is not recommended Article Text Commentaries Pharmacological interventions Routine use of antipsychotics to prevent or treat delirium is not recommended Taro Kishi Statistics from Altmetric.com ABSTRACT FROM : Neufeld KJ, Yue J, Robinson TN, et al . Antipsychotic medication for prevention

Evidence-Based Mental Health2016

68. Systematic review and meta-analysis: Earplugs might reduce intensive care unit delirium but quality of evidence is low

Systematic review and meta-analysis: Earplugs might reduce intensive care unit delirium but quality of evidence is low Earplugs might reduce intensive care unit delirium but quality of evidence is low | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword (...) Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Earplugs might reduce intensive care unit delirium but quality of evidence is low Article Text Therapeutics/Prevention Systematic review and meta-analysis Earplugs might reduce intensive care unit delirium but quality of evidence is low Anica C Law 1 , Allan J Walkey 2 Statistics from Altmetric.com

Evidence-Based Medicine (Requires free registration)2016

69. Pediatric delirium and associated risk factors: a single-center prospective observational study

Pediatric delirium and associated risk factors: a single-center prospective observational study PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2015

70. Constant Observation Monitors for Geriatric Patients with Dementia or Delirium: Clinical and Cost-Effectiveness

Constant Observation Monitors for Geriatric Patients with Dementia or Delirium: Clinical and Cost-Effectiveness Constant Observation Monitors for Geriatric Patients with Dementia or Delirium: Clinical and Cost-Effectiveness | CADTH.ca Find the information you need Constant Observation Monitors for Geriatric Patients with Dementia or Delirium: Clinical and Cost-Effectiveness Constant Observation Monitors for Geriatric Patients with Dementia or Delirium: Clinical and Cost-Effectiveness Published (...) on: September 10, 2015 Project Number: RA0806-000 Product Line: Research Type: Devices and Systems Report Type: Reference List Result type: Report Question What is the clinical effectiveness of using constant observation monitors for geriatric patients with dementia or delirium? What is the cost-effectiveness of using constant observation monitors for geriatric patients with dementia or delirium? Key Message No relevant literature was identified regarding the clinical or cost-effectiveness of using constant

Canadian Agency for Drugs and Technologies in Health - Rapid Review2015

71. The Diagnostic Performance of the Richmond Agitation Sedation Scale for Detecting Delirium in Older Emergency Department Patients

The Diagnostic Performance of the Richmond Agitation Sedation Scale for Detecting Delirium in Older Emergency Department Patients 26113020 2015 07 15 2016 02 03 2017 02 20 1553-2712 22 7 2015 Jul Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Acad Emerg Med The Diagnostic Performance of the Richmond Agitation Sedation Scale for Detecting Delirium in Older Emergency Department Patients. 878-82 10.1111/acem.12706 Delirium is frequently missed (...) in older emergency department (ED) patients. Brief (<2 minutes) delirium assessments have been validated for the ED, but some ED health care providers may consider them to be cumbersome. The Richmond Agitation Sedation Scale (RASS) is an observational scale that quantifies level of consciousness and takes less than 10 seconds to perform. The authors sought to explore the diagnostic accuracy of the RASS for delirium in older ED patients. This was a preplanned analysis of a prospective observational

EvidenceUpdates2015 Full Text: Link to full Text with Trip Pro

72. Intraoperative tight glucose control using hyperinsulinemic normoglycemia increases delirium after cardiac surgery

Intraoperative tight glucose control using hyperinsulinemic normoglycemia increases delirium after cardiac surgery 25992877 2015 05 21 2015 07 24 2016 12 15 1528-1175 122 6 2015 Jun Anesthesiology Anesthesiology Intraoperative tight glucose control using hyperinsulinemic normoglycemia increases delirium after cardiac surgery. 1214-23 10.1097/ALN.0000000000000669 Postoperative delirium is common in patients recovering from cardiac surgery. Tight glucose control has been shown to reduce mortality (...) and morbidity. Therefore, the authors sought to determine the effect of tight intraoperative glucose control using a hyperinsulinemic-normoglycemic clamp approach on postoperative delirium in patients undergoing cardiac surgery. The authors enrolled 198 adult patients having cardiac surgery in this randomized, double-blind, single-center trial. Patients were randomly assigned to either tight intraoperative glucose control with a hyperinsulinemic-normoglycemic clamp (target blood glucose, 80 to 110 mg/dl

EvidenceUpdates2015 Full Text: Link to full Text with Trip Pro

73. Treatment of Older Adults with Insomnia, Agitation, or Delirium with Benzodiazepines

Treatment of Older Adults with Insomnia, Agitation, or Delirium with Benzodiazepines Disclaimer: The Rapid Response Service is an information service for those involved in planning and providing health care in Canada. Rapid responses are based on a limited literature search and are not comprehensive, systematic reviews. The intent is to provide a list of sources of the best evidence on the topic that CADTH could identify using all reasonable efforts within the time allowed. Rapid responses (...) with Insomnia, Agitation, or Delirium with Benzodiazepines: Clinical Effectiveness and Guidelines DATE: 17 April 2015 RESEARCH QUESTIONS 1. What is the clinical effectiveness of the treatment of older adults with insomnia, agitation, or delirium with benzodiazepines or other sedative hypnotic agents? 2. What are the evidence-based guidelines for the treatment of older adults with insomnia, agitation, or delirium with benzodiazepines or other sedative hypnotic agents? KEY FINDINGS Three systematic reviews

Canadian Agency for Drugs and Technologies in Health - Rapid Review2015

74. Delirium

Delirium Scottish Palliative Care Guidelines - Delirium Scottish Palliative Care Guidelines search / / / Delirium Delirium Introduction In this guideline, delirium is defined as disturbed consciousness and inattention with cognitive impairment; acute onset and fluctuating course as a physiological consequence of disease or treatment. Delirium is often reversible. Other terms used to describe delirium include acute confusional state, agitation, and terminal restlessness, but the terms (...) and deafness are risk factors. Differential diagnosis: , dementia (increased risk of developing delirium). Investigations Check full blood count and biochemistry, including calcium Check for infection (urine infection in the elderly) Review all medication and stop any non-essential drugs Assess for sensory impairment Check for opioid toxicity (drowsiness, agitation, myoclonus, hypersensitivity to touch) reduce opioid dose by 1/3rd. Consider switching to another opioid if delirium persists Check

Scottish Palliative Care Guidelines2015

75. Delirium risk stratification in consecutive unselected admissions to acute medicine: validation of externally derived risk scores

Delirium risk stratification in consecutive unselected admissions to acute medicine: validation of externally derived risk scores 26764396 2016 01 14 2016 10 11 2017 02 20 1468-2834 45 1 2016 Jan Age and ageing Age Ageing Delirium risk stratification in consecutive unselected admissions to acute medicine: validation of externally derived risk scores. 60-5 10.1093/ageing/afv177 reliable delirium risk stratification will aid recognition, anticipation and prevention and will facilitate targeting (...) of resources in clinical practice as well as identification of at-risk patients for research. Delirium risk scores have been derived for acute medicine, but none has been prospectively validated in external cohorts. We therefore aimed to determine the reliability of externally derived risk scores in a consecutive cohort of older acute medicine patients. consecutive patients aged ≥65 over two 8-week periods (2010, 2012) were screened prospectively for delirium using the Confusion Assessment Method (CAM

EvidenceUpdates2015 Full Text: Link to full Text with Trip Pro

76. The 3D-CAM provides a brief, easy to use, sensitive and specific delirium assessment tool for older hospitalised patients, both with and without dementia

The 3D-CAM provides a brief, easy to use, sensitive and specific delirium assessment tool for older hospitalised patients, both with and without dementia The 3D-CAM provides a brief, easy to use, sensitive and specific delirium assessment tool for older hospitalised patients, both with and without dementia | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here The 3D-CAM provides a brief, easy to use, sensitive and specific delirium assessment tool for older hospitalised patients, both with and without dementia Article Text Outcomes The 3D-CAM provides

Evidence-Based Mental Health2015

77. 3D-CAM: Derivation and Validation of a 3-Minute Diagnostic Interview for CAM-Defined Delirium: A Cross-sectional Diagnostic Test Study.

3D-CAM: Derivation and Validation of a 3-Minute Diagnostic Interview for CAM-Defined Delirium: A Cross-sectional Diagnostic Test Study. BACKGROUND: Delirium is common, leads to other adverse outcomes, and is costly. However, it often remains unrecognized in most clinical settings. The Confusion Assessment Method (CAM) is the most widely used diagnostic algorithm, and operationalizing its features would be a substantial advance for clinical care. OBJECTIVE: To derive the 3D-CAM, a new 3-minute (...) diagnostic assessment for CAM-defined delirium, and validate it against a clinical reference standard. DESIGN: Derivation and validation study. SETTING: 4 general medicine units in an academic medical center. PARTICIPANTS: 201 inpatients aged 75 years or older. MEASUREMENTS: 20 items that best operationalized the 4 CAM diagnostic features were identified to create the 3D-CAM. For prospective validation, 3D-CAM assessments were administered by trained research assistants. Clinicians independently did

Annals of Internal Medicine2014 Full Text: Link to full Text with Trip Pro

78. Cornell Assessment of Pediatric Delirium: A Valid, Rapid, Observational Tool for Screening Delirium in the PICU

Cornell Assessment of Pediatric Delirium: A Valid, Rapid, Observational Tool for Screening Delirium in the PICU PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2014

79. Tryptophan Supplementation and Postoperative Delirium-A Randomized Controlled Trial

Tryptophan Supplementation and Postoperative Delirium-A Randomized Controlled Trial 25112175 2014 09 23 2014 12 03 2017 02 20 1532-5415 62 9 2014 Sep Journal of the American Geriatrics Society J Am Geriatr Soc Tryptophan supplementation and postoperative delirium--a randomized controlled trial. 1764-71 10.1111/jgs.12972 To determine whether the postoperative administration of tryptophan would be beneficial for elderly adults undergoing surgery who are at risk of developing postoperative (...) delirium. Randomized, double-blind, placebo-controlled trial. Denver Veterans Affairs Medical Center. Individuals aged 60 and older undergoing major elective operations requiring a postoperative intensive care unit (ICU) admission (n = 325). L-tryptophan, 1 g orally three times a day or placebo was started after surgery and continued for up to 3 days postoperatively. Delirium and its motor subtypes were measured using the Confusion Assessment Method-Intensive Care Unit (CAM-ICU) and the Richmond

EvidenceUpdates2014 Full Text: Link to full Text with Trip Pro

80. Excited Delirium Syndrome and Sudden Death

Excited Delirium Syndrome and Sudden Death BestBets: Excited Delirium Syndrome and Sudden Death Excited Delirium Syndrome and Sudden Death Report By: Karl Huesgen, MD - Resident Physician Search checked by Bryan Judge MD - Faculty Physician Institution: Grand Rapids Medical Education Partners/Michigan State University, USA Date Submitted: 7th September 2012 Date Completed: 24th February 2014 Last Modified: 24th February 2014 Status: Green (complete) Three Part Question In [adult patients (...) ] presenting to the Emergency Department with suspected [excited delirium syndrome], what are the [clinical features associated with significant morbidity and mortality]? Clinical Scenario You are working a shift in an Emergency Department (ED), and you receive a call from prehospital providers requesting advice in management of a violent and incoherent patient with strength far in excess of expected for his size. This seems consistent with reports you have read of Excited Delirium Syndrome (EXDS). You

BestBETS2014