Latest & greatest articles for covid-19

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on covid-19 or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on covid-19 and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for covid-19

121. Effects of non-drug interventions on depression, anxiety and sleep in COVID-19 patients: a systematic review and meta-analysis

Effects of non-drug interventions on depression, anxiety and sleep in COVID-19 patients: a systematic review and meta-analysis Effects of non-drug interventions on depression, anxiety and sleep in COVID-19 patients: a systematic review and meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging (...) Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Meta-Analysis Eur Rev Med Pharmacol Sci Actions . 2021 Jan;25(2):1087-1096. doi: 10.26355/eurrev_202101_24679. Effects of non-drug interventions on depression, anxiety and sleep in COVID-19 patients: a systematic review and meta-analysis , , , , Affiliations Expand Affiliation 1 Department of Intensive Care Unit, General Hospital

2021 EvidenceUpdates

122. Prognostic Accuracy of Early Warning Scores for Clinical Deterioration in Patients With COVID-19 Full Text available with Trip Pro

target. Ann Transl Med. (2020) 8:694 10.21037/atm-20-2793 - - - Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. (2020) 382:727–33. 10.1056/NEJMoa2001017 - - - Tonetti T, Grasselli G, Zanella A, Pizzilli G, Fumagalli R, Piva S, et al. Use of critical care resources during the first 2 weeks (February 24-March 8, 2020) of the Covid-19 outbreak in Italy. Ann Intensive Care. (2020) 10:133 10.1186/s13613-020-00750-z (...) Prognostic Accuracy of Early Warning Scores for Clinical Deterioration in Patients With COVID-19 Prognostic Accuracy of Early Warning Scores for Clinical Deterioration in Patients With COVID-19 - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Show account info Close Account Logged

2021 EvidenceUpdates

123. An updated systematic review and network meta-analysis of 25 randomized trials assessing the efficacy and safety of treatments in COVID-19 disease

An updated systematic review and network meta-analysis of 25 randomized trials assessing the efficacy and safety of treatments in COVID-19 disease EvidenceAlerts | Log In '); '); New and Improved! EvidenceAlerts has been re-designed to optimize function on all media devices. Content, alerting and search functions remain the same, but appearance on tablets and smart phones has been enhanced. most welcome! Email Address Password Remember me? Stellar Articles Hit Parade EvidenceAlerts COVID-19 (...) Evidence Alerts from McMaster PLUS is a new service that alerts users to current best evidence for clinical care of people with threatened, suspected or confirmed COVID-19 infection. Please sign in Email Address Password Remember me? Mailing Address Health Information Research Unit McMaster University Communications Research Lab, First Floor 1280 Main Street West Hamilton, Ontario L8S 4K1 Canada Contact Us Social Media: Phone: Email: Legal Information Share us on... © 2021 , McMaster University × OK

2021 EvidenceUpdates

124. Use of the first National Early Warning Score recorded within 24 hours of admission to estimate the risk of in-hospital mortality in unplanned COVID-19 patients: a retrospective cohort study Full Text available with Trip Pro

Use of the first National Early Warning Score recorded within 24 hours of admission to estimate the risk of in-hospital mortality in unplanned COVID-19 patients: a retrospective cohort study Use of the first National Early Warning Score recorded within 24 hours of admission to estimate the risk of in-hospital mortality in unplanned COVID-19 patients: a retrospective cohort study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set (...) of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Show account info Close Account Logged in as: username Search: Search Save Email Send to Display options Display options Format Save citation to file Format: Create file Cancel Email citation Subject: 1 selected item: 33619194 - PubMed To: Format: MeSH and other data Send email Cancel Add to Collections Create a new collection Add to an existing

2021 EvidenceUpdates

125. A Rapid, High-Sensitivity SARS-CoV-2 Nucleocapsid Immunoassay to Aid Diagnosis of Acute COVID-19 at the Point of Care: A Clinical Performance Study Full Text available with Trip Pro

. Brischetto A, et al. Aust Prescr. 2020 Dec;43(6):204-208. doi: 10.18773/austprescr.2020.067. Epub 2020 Oct 15. Aust Prescr. 2020. PMID: 33363303 Free PMC article. Review. References World Health Organization. Health emergencies, coronavirus disease (COVID-19) outbreak. 2020. . Accessed 21 Oct 2020. Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–733. doi: 10.1056/nejmoa2001017. - - - Siordia JA. Epidemiology and clinical features (...) A Rapid, High-Sensitivity SARS-CoV-2 Nucleocapsid Immunoassay to Aid Diagnosis of Acute COVID-19 at the Point of Care: A Clinical Performance Study A Rapid, High-Sensitivity SARS-CoV-2 Nucleocapsid Immunoassay to Aid Diagnosis of Acute COVID-19 at the Point of Care: A Clinical Performance Study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily

2021 EvidenceUpdates

126. Interferon-beta offers promising avenues to COVID-19 treatment: a systematic review and meta-analysis of clinical trial studies Full Text available with Trip Pro

Interferon-beta offers promising avenues to COVID-19 treatment: a systematic review and meta-analysis of clinical trial studies Interferon-beta offers promising avenues to COVID-19 treatment: a systematic review and meta-analysis of clinical trial studies - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging (...) Name of RSS Feed: Number of items displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Review Naunyn Schmiedebergs Arch Pharmacol Actions . 2021 Feb 15;1-10. doi: 10.1007/s00210-021-02061-x. Online ahead of print. Interferon-beta offers promising avenues to COVID-19 treatment: a systematic review and meta-analysis of clinical trial studies , , Affiliations Expand Affiliations 1 Research Center of Psychiatry

2021 EvidenceUpdates

127. Systematic review and meta-analysis of anakinra, sarilumab, siltuximab and tocilizumab for COVID-19 Full Text available with Trip Pro

features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet 2020;395:497–506.10.1016/S0140-6736(20)30183-5 - - - WHO Director-General’s opening remarks at the media briefing on COVID-19, 2020. Available: [Accessed 11 Mar 2020]. Johns Hopkins University (JHU) Johns Hopkins University of medicine COVID-19 dashboard by the center for systems science and engineering (CSSE). Available: Mehta P, McAuley DF, Brown M, et al. . COVID-19: consider cytokine storm syndromes (...) Systematic review and meta-analysis of anakinra, sarilumab, siltuximab and tocilizumab for COVID-19 Systematic review and meta-analysis of anakinra, sarilumab, siltuximab and tocilizumab for COVID-19 - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Show account info Close Account

2021 EvidenceUpdates

128. Pragmatic Recommendations for the Use of Diagnostic Testing and Prognostic Models in Hospitalized Patients with Severe COVID-19 in Low- and Middle-Income Countries Full Text available with Trip Pro

Pragmatic Recommendations for the Use of Diagnostic Testing and Prognostic Models in Hospitalized Patients with Severe COVID-19 in Low- and Middle-Income Countries Pragmatic Recommendations for the Use of Diagnostic Testing and Prognostic Models in Hospitalized Patients with Severe COVID-19 in Low- and Middle-Income Countries - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other (...) advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Show account info Close Account Logged in as: username Search: Search Save Email Send to Display options Display options Format Save citation to file Format: Create file Cancel Email citation Subject: 1 selected item: 33534752 - PubMed To: Format: MeSH and other data Send email Cancel Add to Collections Create a new collection Add to an existing collection Name your collection: Name must be less than 100

2021 EvidenceUpdates

129. Validating the RISE UP score for predicting prognosis in patients with COVID-19 in the emergency department: a retrospective study Full Text available with Trip Pro

2020;395:507–13. 10.1016/S0140-6736(20)30211-7 - - - Sohrabi C, Alsafi Z, O'Neill N, et al. . World Health organization declares global emergency: a review of the 2019 novel coronavirus (COVID-19). Int J Surg 2020;76:71–6. 10.1016/j.ijsu.2020.02.034 - - - World Health Organization . Coronavirus disease (COVID-19): situation report - 134, 2020. Available: worldmeter . COVID-19 coronavirus pandemic, 2020. Available: Guan W-J, Ni Z-Y, Hu Y, et al. . Clinical characteristics of coronavirus disease 2019 (...) Validating the RISE UP score for predicting prognosis in patients with COVID-19 in the emergency department: a retrospective study Validating the RISE UP score for predicting prognosis in patients with COVID-19 in the emergency department: a retrospective study - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging

2021 EvidenceUpdates

130. Remdesivir for treatment of COVID-19; an updated systematic review and meta-analysis Full Text available with Trip Pro

Remdesivir for treatment of COVID-19; an updated systematic review and meta-analysis Remdesivir for treatment of COVID-19; an updated systematic review and meta-analysis - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Show account info Close Account Logged in as: username Search (...) Cite Display options Display options Format Share Permalink Copy Page navigation Meta-Analysis Eur J Pharmacol Actions . 2021 Apr 15;897:173926. doi: 10.1016/j.ejphar.2021.173926. Epub 2021 Feb 4. Remdesivir for treatment of COVID-19; an updated systematic review and meta-analysis , , , Affiliations Expand Affiliations 1 Department of Clinical Pharmacy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. 2 Assistant Professor of Biostatistics, Department of Statistics

2021 EvidenceUpdates

131. Safety and effectiveness of high-dose vitamin C in patients with COVID-19: a randomized open-label clinical trial Full Text available with Trip Pro

Safety and effectiveness of high-dose vitamin C in patients with COVID-19: a randomized open-label clinical trial Safety and effectiveness of high-dose vitamin C in patients with COVID-19: a randomized open-label clinical trial - PubMed This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable. COVID-19 is an emerging, rapidly evolving situation. Show (...) displayed: Create RSS Cancel RSS Link Copy Actions Cite Display options Display options Format Share Permalink Copy Page navigation Randomized Controlled Trial Eur J Med Res Actions . 2021 Feb 11;26(1):20. doi: 10.1186/s40001-021-00490-1. Safety and effectiveness of high-dose vitamin C in patients with COVID-19: a randomized open-label clinical trial , , , , , , , , , , , , , , , , Affiliations Expand Affiliations 1 Department of Infectious Diseases, Ziayian Hospital, Tehran University of Medical

2021 EvidenceUpdates

132. COVID-19: migrant health guide

COVID-19: migrant health guide COVID-19: migrant health guide - GOV.UK Cookies on GOV.UK We use some essential cookies to make this website work. We’d like to set additional cookies to understand how you use GOV.UK, remember your settings and improve government services. We also use cookies set by other sites to help us deliver content from their services. Accept additional cookies Reject additional cookies You can at any time. Hide this message Show or hide search Search on GOV.UK Search Menu (...) National lockdown: stay at home Check what you need to do Guidance COVID-19: migrant health guide Advice and guidance for healthcare practitioners on the health needs of migrant patients. Published 17 February 2021 From: Contents Print this page No charges for coronavirus (COVID-19) testing, treatment and vaccination Overseas visitors to England, including anyone living in the UK without permission, will not be charged for: testing for COVID-19 (even if the test shows they do not have COVID-19

2021 Public Health England

133. Safety of COVID-19 vaccines when given in pregnancy

Safety of COVID-19 vaccines when given in pregnancy Safety of COVID-19 vaccines when given in pregnancy - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Show or hide search Search on GOV.UK Search Menu National lockdown: stay at home Check how the new rules affect you Guidance Safety of COVID (...) -19 vaccines when given in pregnancy Guidance for health professionals to share with pregnant women immunised with COVID-19 vaccines. Published 18 December 2020 Last updated 5 January 2021 — From: Documents HTML Details This advice provides information on the safety of COVID-19 vaccines when given in pregnancy. It is designed for health professionals to share with women who were vaccinated before they knew they were pregnant. An is available to download. Published 18 December 2020 Last updated 5

2021 Public Health England

134. COVID-19 rapid evidence summary: Tocilizumab for COVID-19

COVID-19 rapid evidence summary: Tocilizumab for COVID-19 COVID-19 rapid evidence summary: T ocilizumab for COVID-19 Evidence summary Published: 15 January 2021 www.nice.org.uk/guidance/es33 pathways Product overview Product overview The content of this evidence summary was up to date in January 2021. See summaries of product characteristics (SPCs), British national formulary (BNF) or the Medicines and Healthcare products Regulatory Agency (MHRA) or NICE websites for up-to-date information. T (...) ocilizumab is an interleukin-6 inhibitor. It has marketing authorisations for rheumatoid arthritis and giant cell arteritis in adults, systemic juvenile idiopathic arthritis and juvenile idiopathic polyarthritis in children 2 years and older, and chimeric antigen receptor T cell-induced severe or life-threatening cytokine release syndrome in adults, young people and children 2 years and older (see the summaries of product characteristics for tocilizumab). Use of tocilizumab for COVID-19 is off label

2021 National Institute for Health and Clinical Excellence - Advice

135. Preventing and controlling outbreaks of COVID-19 in prisons and places of detention

Preventing and controlling outbreaks of COVID-19 in prisons and places of detention COVID-19: prisons and other prescribed places of detention guidance - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance COVID-19: prisons and other prescribed places of detention guidance (...) Information for prisons and other prescribed places of detention on coronavirus (COVID-19). Published 16 March 2020 From: and Documents HTML Details This guidance will assist healthcare staff and custodial/detention staff in addressing coronavirus (COVID-19) in prescribed places of detention ( Explore the topic Is this page useful? Thank you for your feedback Help us improve GOV.UK Don’t include personal or financial information like your National Insurance number or credit card details. What were you

2021 Public Health England

136. Coronavirus (COVID-19) infection and pregnancy

Xue Za Zhi 2020;49(0):E005-E05. doi: 10.3760/cma.j.cn112151-20200225-00138 4 Wang X, Zhou Z, Zhang J, et al. A case of 2019 Novel Coronavirus in a pregnant woman with pre- term delivery. Clinical Infectious Diseases 2020 doi: https://doi.org/10.1093/cid/ciaa200 5 Zhang J, Wang Y, Chen L, et al. Clinical analysis of pregnancy in second and third trimesters com- plicated severe acute respiratory syndrome. Zhonghua Fu Chan Ke Za Zhi 2003;38:516-20. 6 Travel advice: coronavirus (COVID-19) 2020 (...) [Available from: https://www.gov.uk/guidance/trav- el-advice-novel-coronavirus accessed 05 March 2020. 7 Self-isolation advice-Coronavirus (COVID-19) 2020 [Available from: https://www.nhs.uk/condi- tions/coronavirus-covid-19/self-isolation-advice/ accessed 05 March 2020. 8 COVID-19: investigation and initial clinical management of possible cases 2020 [Available from: https://www.gov.uk/government/publications/wuhan-novel-coronavirus-initial-investigation-of-possi- ble-cases/investigation-and-initial

2021 Royal College of Obstetricians and Gynaecologists

137. Maternity care for mothers and babies during the COVID-19 pandemic

clinical assessment Is self-quarantine indicated? Routine/usual care (for COVID-19 pandemic) Is isolation indicated? NO YES NO YES Return to defined restricted area • Two weeks quarantine required to gain Human Biosecurity Approval and Local Council permit • Available at https://www.health.qld.gov.au/clinical- practice/guidelines-procedures/novel-coronavirus-qld- cliniciansQueensland Clinical Guideline: Maternity care for mothers and babies during the COVID-19 pandemic Refer to online version, destroy (...) 14 days, (even if COVID-19 test result negative 2 ) o If close contact with a confirmed or suspected case within previous 14 days • Self-isolation o If confirmed positive COVID-19 o Duration as specified in the current Communicable Disease Network Australia Guidelines for Public Health Units (frequent updates) available at https://www.health.qld.gov.au/clinical-practice/guidelines- procedures/novel-coronavirus-qld-clinicians Advice for self- quarantine/isolation • Do not o Go out (e.g. to school

2021 Queensland Health

138. COVID-19: guidance on supporting children and young people’s mental health and wellbeing

COVID-19: guidance on supporting children and young people’s mental health and wellbeing COVID-19: guidance on supporting children and young people’s mental health and wellbeing - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance and support Part of Guidance COVID-19: guidance (...) on supporting children and young people’s mental health and wellbeing Advice for parents and carers on looking after the mental health and wellbeing of children or young people during the coronavirus (COVID-19) outbreak. Published 29 March 2020 Last updated 14 September 2020 — From: Documents HTML Ref: PHE publications gateway number GW-1212 . Please tell us what format you need. It will help us if you say what assistive technology you use. . Please tell us what format you need. It will help us if you say

2021 Public Health England

139. Coronavirus (COVID-19): Keeping children safe from abuse and harm

Coronavirus (COVID-19): Keeping children safe from abuse and harm Coronavirus (COVID-19): Keeping children safe from abuse and harm - GOV.UK Tell us whether you accept cookies We use about how you use GOV.UK. We use this information to make the website work as well as possible and improve government services. Accept all cookies You’ve accepted all cookies. You can at any time. Hide Search Guidance and support Guidance Coronavirus (COVID-19): Keeping children safe from abuse and harm Advice (...) for parents and carers about the main risks children may be particularly vulnerable to at this time and information about available help and support. Published 25 June 2020 From: , , , and Documents HTML Details This guidance brings together sources of information about the main risks children may be particularly vulnerable to during the coronavirus (COVID-19) pandemic and signposts you to help and support available. Published 25 June 2020 Related content Explore the topic Is this page useful? Thank you

2021 Public Health England

140. Covid-19 : Follow Prescrire's independent, evidence-based analysis of the pandemic

Covid-19 : Follow Prescrire's independent, evidence-based analysis of the pandemic Prescrire IN ENGLISH - Spotlight ''Covid-19 : Follow Prescrire's independent, evidence-based analysis of the pandemic'', 24 June 2020 {1} {1} {1} | | > > > Covid-19 : Follow Prescrire's independent, evidence-based analysis of the pandemic Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |  (...)  |  Spotlight Covid-19 : Follow Prescrire's independent, evidence-based analysis of the pandemic COVID-19 Prescrire's editors are publishing an ongoing series of news updates featuring independent analysis of developments related to the covid-19 pandemic. Useful and practical information, to help healthcare professionals gain a clear and balanced view. "Covid-19 and severe breathing problems: dexamethasone reduced mortality in one trial" (24 June 2020) "Lack of access to drug evaluation data

2021 Prescrire