Latest & greatest articles for corticosteroids

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Top results for corticosteroids

21. Effectiveness of Oral Pain Medication and Corticosteroid Injections for Carpal Tunnel Syndrome: A Systematic Review

Effectiveness of Oral Pain Medication and Corticosteroid Injections for Carpal Tunnel Syndrome: A Systematic Review 29626428 2018 07 28 1532-821X 99 8 2018 Aug Archives of physical medicine and rehabilitation Arch Phys Med Rehabil Effectiveness of Oral Pain Medication and Corticosteroid Injections for Carpal Tunnel Syndrome: A Systematic Review. 1609-1622.e10 S0003-9993(18)30210-7 10.1016/j.apmr.2018.03.003 To present an evidence-based overview of the effectiveness of oral pain medication (...) and corticosteroid injections to treat carpal tunnel syndrome (CTS). The Cochrane Library, PubMed, Embase, CINAHL, and Physiotherapy Evidence Database were searched for relevant systematic reviews and randomized controlled trials (RCTs). Two reviewers independently applied the inclusion criteria to select potential studies. Two reviewers independently extracted the data on pain (visual analog scale), function or recovery, and assessed the methodologic quality. A best-evidence synthesis was performed to summarize

EvidenceUpdates2018

22. Efficacy of Rituximab vs Tacrolimus in Pediatric Corticosteroid-Dependent Nephrotic Syndrome: A Randomized Clinical Trial

Efficacy of Rituximab vs Tacrolimus in Pediatric Corticosteroid-Dependent Nephrotic Syndrome: A Randomized Clinical Trial 29913001 2018 08 08 2168-6211 172 8 2018 Aug 01 JAMA pediatrics JAMA Pediatr Efficacy of Rituximab vs Tacrolimus in Pediatric Corticosteroid-Dependent Nephrotic Syndrome: A Randomized Clinical Trial. 757-764 10.1001/jamapediatrics.2018.1323 Calcineurin inhibitors are an established first-line corticosteroid-sparing therapy for patients with corticosteroid-dependent nephrotic (...) , with 1-year follow-up in a single-center, tertiary care unit. A total of 176 consecutive children aged 3 to 16 years with CDNS not previously treated with corticosteroid-sparing agents were screened for eligibility. The children received either tacrolimus (along with tapering alternate-day prednisolone) for 12 months or a single course of rituximab (2 infusions of 375 mg/m2). Twelve-month relapse-free survival in the intention-to-treat population. Of the 176 children screened for eligibility, 120

EvidenceUpdates2018

23. Low back pain: no corticosteroids

Low back pain: no corticosteroids Prescrire IN ENGLISH - Spotlight ''Low back pain: no corticosteroids '', 1 September 2018 {1} {1} {1} | | > > > Low back pain: no corticosteroids Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight Low back pain: no corticosteroids There is no evidence that systemic corticosteroids have any efficacy on low (...) back pain, beyond a placebo effect. Furthermore, they expose patients to numerous adverse effects. Low back pain is common in adults. It is sometimes accompanied by pain spreading into the lower limbs (radiculalgia). In most cases, it improves spontaneously, within a few days or weeks. When low back pain persists for more than three months, it is termed chronic. In most cases, there is no identifiable cause. Several trials have compared systemic corticosteroid therapy with a placebo. Their results converge

Prescrire2018

24. Once-daily long-acting beta₂-agonists/inhaled corticosteroids combined inhalers versus inhaled long-acting muscarinic antagonists for people with chronic obstructive pulmonary disease.

Once-daily long-acting beta₂-agonists/inhaled corticosteroids combined inhalers versus inhaled long-acting muscarinic antagonists for people with chronic obstructive pulmonary disease. BACKGROUND: Three classes of inhaler medication are used to manage chronic obstructive pulmonary disease (COPD): long-acting beta₂-agonists (LABA); long-acting muscarinic antagonists (LAMA); and inhaled corticosteroids (ICS). To encourage patient adherence, two classes of medication are often combined in a single (...) medication device; it seems that once-daily dosing offers greatest convenience to patients and may markedly influence adherence. OBJECTIVES: To compare a once-daily combination of inhaled corticosteroid and long-acting beta₂-agonist inhalers (ICS/LABA) versus inhaled long-acting muscarinic antagonists alone (LAMA) for people with chronic obstructive pulmonary disease (COPD). SEARCH METHODS: We performed an electronic search of the Specialised Register of the Cochrane Airways Group (14 May 2018

Cochrane2018

25. Corticosteroids for preventing neonatal respiratory morbidity after elective caesarean section at term.

Corticosteroids for preventing neonatal respiratory morbidity after elective caesarean section at term. BACKGROUND: Infants born at term by elective caesarean section are more likely to develop respiratory morbidity than infants born vaginally. Prophylactic corticosteroids in singleton preterm pregnancies accelerate lung maturation and reduce the incidence of respiratory complications. OBJECTIVES: The objective of this review was to assess the effect of prophylactic corticosteroid (...) administration before elective caesarean section at term, as compared to usual management without corticosteroids, in reducing neonatal respiratory morbidity and admission to special care with respiratory complications. SEARCH METHODS: We searched Cochrane Pregnancy and Childbirth's Trials Register (14 June 2017), and reference lists of retrieved studies. SELECTION CRITERIA: Randomised controlled trials comparing prophylactic antenatal corticosteroid administration (betamethasone or dexamethasone

Cochrane2018

26. Corticosteroids in Sepsis: An Updated Systematic Review and Meta-Analysis

Corticosteroids in Sepsis: An Updated Systematic Review and Meta-Analysis 29979221 2018 08 16 1530-0293 46 9 2018 Sep Critical care medicine Crit. Care Med. Corticosteroids in Sepsis: An Updated Systematic Review and Meta-Analysis. 1411-1420 10.1097/CCM.0000000000003262 This systematic review and meta-analysis addresses the efficacy and safety of corticosteroids in critically ill patients with sepsis. We updated a comprehensive search of MEDLINE, EMBASE, CENTRAL, and LILACS, and unpublished (...) sources for randomized controlled trials that compared any corticosteroid to placebo or no corticosteroid in critically ill children and adults with sepsis. Reviewers conducted duplicate screening of citations, data abstraction, and, using a modified Cochrane risk of bias tool, individual study risk of bias assessment. A parallel guideline committee provided input on the design and interpretation of the systematic review, including the selection of outcomes important to patients. We assessed overall

EvidenceUpdates2018

27. Lumbar Epidural Corticosteroid Injection Reduces Subacute Pain and Improves Knee Function in the First Six Weeks After Total Knee Arthroplasty: A Double-Blinded Randomized Trial

Lumbar Epidural Corticosteroid Injection Reduces Subacute Pain and Improves Knee Function in the First Six Weeks After Total Knee Arthroplasty: A Double-Blinded Randomized Trial 29870446 2018 06 05 1535-1386 100 11 2018 Jun 06 The Journal of bone and joint surgery. American volume J Bone Joint Surg Am Lumbar Epidural Corticosteroid Injection Reduces Subacute Pain and Improves Knee Function in the First Six Weeks After Total Knee Arthroplasty: A Double-Blinded Randomized Trial. 950-957 10.2106 (...) /JBJS.17.00578 Pain control immediately following total knee arthroplasty (TKA) has been a focus for orthopaedists. However, control of subacute pain, which may persist up to 3 months, is usually not optimized. The efficacy of epidural corticosteroids in reducing pain after surgery is documented, but data on their efficacy in controlling subacute pain after TKA are lacking. Our aim was to investigate the efficacy of an epidural corticosteroid in controlling pain in the first 3 months following TKA

EvidenceUpdates2018

28. Corticosteroids

Corticosteroids Top results for corticosteroids - Trip Database or use your Google+ account Turning Research Into Practice My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box (...) and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for corticosteroids The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical

Trip Latest and Greatest2018

29. Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo-a Meta-analysis of Individual Data From Controlled Trials

Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo-a Meta-analysis of Individual Data From Controlled Trials 29738698 2018 08 13 2018 08 13 1528-0012 155 2 2018 08 Gastroenterology Gastroenterology Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo-a Meta-analysis of Individual Data From Controlled Trials. 458-468.e8 S0016 (...) -5085(18)34495-0 10.1053/j.gastro.2018.05.011 We performed a meta-analysis of individual patient data from 11 randomized controlled trials comparing corticosteroids, pentoxifylline, or their combination in patients with severe alcoholic hepatitis. We compared the effects of the treatments on survival for 28 days or 6 months, and response to treatment based on the Lille model. We searched PubMed for randomized controlled trials of pharmacologic therapy for severe alcoholic hepatitis. Our final

EvidenceUpdates2018

30. Intensified Therapy with Inhaled Corticosteroids and Long-Acting beta2-Agonists at the Onset of Upper Respiratory Tract Infection to Prevent Chronic Obstructive Pulmonary Disease Exacerbations. A Multicenter, Randomized, Double-Blind, Placebo-controlled T

Intensified Therapy with Inhaled Corticosteroids and Long-Acting beta2-Agonists at the Onset of Upper Respiratory Tract Infection to Prevent Chronic Obstructive Pulmonary Disease Exacerbations. A Multicenter, Randomized, Double-Blind, Placebo-controlled T 29266965 2018 05 01 1535-4970 197 9 2018 May 01 American journal of respiratory and critical care medicine Am. J. Respir. Crit. Care Med. Intensified Therapy with Inhaled Corticosteroids and Long-Acting β 2 -Agonists at the Onset of Upper (...) Respiratory Tract Infection to Prevent Chronic Obstructive Pulmonary Disease Exacerbations. A Multicenter, Randomized, Double-Blind, Placebo-controlled Trial. 1136-1146 10.1164/rccm.201709-1807OC The efficacy of intensified combination therapy with inhaled corticosteroids (ICS) and long-acting β 2 -agonists (LABA) at the onset of upper respiratory tract infection (URTI) symptoms in chronic obstructive pulmonary disease (COPD) is unknown. To evaluate whether intensified combination therapy with ICS/LABA

EvidenceUpdates2018

31. Transplacental versus direct fetal corticosteroid treatment for accelerating fetal lung maturation where there is a risk of preterm birth.

Transplacental versus direct fetal corticosteroid treatment for accelerating fetal lung maturation where there is a risk of preterm birth. BACKGROUND: Despite major advances in medical technology, the incidence of preterm birth remains high. The use of antenatal corticosteroid administered transplacentally, by intramuscular injection to women at risk of preterm birth, has reduced the incidence of respiratory distress syndrome and increased the survival rates of preterm infants. However (...) , this intervention also comes with its own risks and side effects. Animal studies and early studies in pregnant women at risk of preterm birth have reported the use of an alternative route of administration, by direct intramuscular injection of corticosteroid into the fetus under ultrasound guidance, in an attempt to minimise the side-effect profile. Direct fetal corticosteroid administration may have benefits over maternal administration in terms of safety and efficacy. OBJECTIVES: To assess if different routes

Cochrane2018

32. Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for acute asthma.

Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for acute asthma. BACKGROUND: Acute asthma is a common cause of presentations to acute care centres, such as the emergency department (ED), and while the majority of patients can be discharged, relapse requiring additional medical care is common. Systemic corticosteroids are a major part in the treatment of moderate to severe acute asthma; however, there is no clear evidence regarding (...) the most effective route of administration for improving outcomes in patients discharged from acute care. OBJECTIVES: To examine the effectiveness and safety of a single dose of intramuscular (IM) corticosteroids provided prior to discharge compared to a short course of oral corticosteroids in the treatment of acute asthma patients discharged from an ED or equivalent acute care setting. SEARCH METHODS: The Cochrane Airways Group conducted searches of the Cochrane Airways Group Register of Trials, most

Cochrane2018

33. Comparison of Ultrasound-Guided Local Ozone (O2-O3) Injection vs Corticosteroid Injection in the Treatment of Chronic Plantar Fasciitis: A Randomized Clinical Trial

Comparison of Ultrasound-Guided Local Ozone (O2-O3) Injection vs Corticosteroid Injection in the Treatment of Chronic Plantar Fasciitis: A Randomized Clinical Trial 29868796 2018 06 05 1526-4637 2018 May 30 Pain medicine (Malden, Mass.) Pain Med Comparison of Ultrasound-Guided Local Ozone (O2-O3) Injection vs Corticosteroid Injection in the Treatment of Chronic Plantar Fasciitis: A Randomized Clinical Trial. 10.1093/pm/pny066 Plantar fasciitis (PF) is one of the most common causes of heel pain (...) . The affected area is often close to the attachment of plantar fascia to calcaneus bone. The purpose of this study was to compare the effects of ozone (O2-O3) injection to corticosteroid injection under ultrasound guidance for the treatment of chronic PF. Randomized clinical trial. Academic University and Neuromusculoskeletal Research Center. Thirty patients with chronic PF. The patients were randomly divided into two groups receiving methylprednisolone (15 subjects) vs ozone (O2-O3; 15 subjects

EvidenceUpdates2018

34. Efficacy and safety of pulmonary application of corticosteroids in preterm infants with respiratory distress syndrome: a systematic review and meta-analysis

Efficacy and safety of pulmonary application of corticosteroids in preterm infants with respiratory distress syndrome: a systematic review and meta-analysis 29666203 2018 04 18 1468-2052 2018 Apr 17 Archives of disease in childhood. Fetal and neonatal edition Arch. Dis. Child. Fetal Neonatal Ed. Efficacy and safety of pulmonary application of corticosteroids in preterm infants with respiratory distress syndrome: a systematic review and meta-analysis. fetalneonatal-2017-314046 10.1136 (...) /archdischild-2017-314046 Systemic corticosteroids as the frontline treatment of respiratory distress syndrome (RDS) in preterm infants are associated with adverse effects on growth and neurodevelopmental outcome, but the pulmonary administration of steroids may help prevent the development of bronchopulmonary dysplasia (BPD) without these side effects. To evaluate the efficacy and safety of pulmonary application of corticosteroids in preterm infants with RDS. MEDLINE, EMBASE, Cochrane Central Register

EvidenceUpdates2018

35. Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ill Patients (Part II)

Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ill Patients (Part II) Guidelines for the Diagnosis and Management of Critical Illn... : Critical Care Medicine You may be trying to access this site from a secured browser on the server. Please enable scripts and reload this page. You currently have no recent searches Enter your Email address: Wolters Kluwer Health may email you for journal alerts and information (...) Care, Department of Medicine, McMaster University, Hamilton, ON, Canada. Dr. Stephen M. Pastores and Dr. Djillali Annane are co-chairs and co-first authors who have equally contributed to this work. A full list of the Corticosteroid Guideline Task Force of SCCM and ESICM investigators is presented in the supplementary material ( Supplemental Digital Content 3 , ). Dr. Pastores participates in the American College of Physicians: Speaker at ACP Critical Care Update Precourse, the American College of Chest

Society of Critical Care Medicine2018 Full Text: Link to full Text with Trip Pro

36. Usefulness of an Online Risk Estimator for Bronchopulmonary Dysplasia in Predicting Corticosteroid Treatment in Infants Born Preterm

Usefulness of an Online Risk Estimator for Bronchopulmonary Dysplasia in Predicting Corticosteroid Treatment in Infants Born Preterm 29551313 2018 05 26 1097-6833 197 2018 Jun The Journal of pediatrics J. Pediatr. Usefulness of an Online Risk Estimator for Bronchopulmonary Dysplasia in Predicting Corticosteroid Treatment in Infants Born Preterm. 23-28.e2 S0022-3476(18)30143-4 10.1016/j.jpeds.2018.01.065 To assess the usefulness of a bronchopulmonary dysplasia (BPD) outcome estimator developed (...) dysplasia postnatal corticosteroids prematurity risk calculator 2017 10 06 2017 12 13 2018 01 24 2018 3 20 6 0 2018 3 20 6 0 2018 3 20 6 0 ppublish 29551313 S0022-3476(18)30143-4 10.1016/j.jpeds.2018.01.065

EvidenceUpdates2018

37. Inhaled corticosteroids for bronchiectasis.

Inhaled corticosteroids for bronchiectasis. BACKGROUND: Bronchiectasis is being increasingly diagnosed and recognised as an important contributor to chronic lung disease in both adults and children in high- and low-income countries. It is characterised by irreversible dilatation of airways and is generally associated with airway inflammation and chronic bacterial infection. Medical management largely aims to reduce morbidity by controlling the symptoms, reduce exacerbation frequency, improve (...) quality of life and prevent the progression of bronchiectasis. This is an update of a review first published in 2000. OBJECTIVES: To evaluate the efficacy and safety of inhaled corticosteroids (ICS) in children and adults with stable state bronchiectasis, specifically to assess whether the use of ICS: (1) reduces the severity and frequency of acute respiratory exacerbations; or (2) affects long-term pulmonary function decline. SEARCH METHODS: We searched the Cochrane Register of Controlled Trials

Cochrane2018

38. Education plus exercise versus corticosteroid injection use versus a wait and see approach on global outcome and pain from gluteal tendinopathy: prospective, single blinded, randomised clinical trial.

Education plus exercise versus corticosteroid injection use versus a wait and see approach on global outcome and pain from gluteal tendinopathy: prospective, single blinded, randomised clinical trial. OBJECTIVE: To compare the effects of a programme of load management education plus exercise, corticosteroid injection use, and no treatment on pain and global improvement in individuals with gluteal tendinopathy. DESIGN: Prospective, three arm, single blinded, randomised clinical trial. SETTING (...) : Brisbane and Melbourne, Australia. PARTICIPANTS: Individuals aged 35-70 years, with lateral hip pain for more than three months, at least 4/10 on the pain numerical rating scale, and gluteal tendinopathy confirmed by clinical diagnosis and magnetic resonance imaging; and with no corticosteroid injection use in previous 12 months, current physiotherapy, total hip replacement, or neurological conditions. INTERVENTIONS: A physiotherapy led education and exercise programme of 14 sessions over eight weeks

BMJ2018 Full Text: Link to full Text with Trip Pro

39. A Randomized, Multicenter, Double-Blind, Parallel Pilot Study Assessing the Effect of Mechanical Adhesiolysis vs Adhesiolysis with Corticosteroid and Hyaluronidase Administration into the Epidural Space During Epiduroscopy

A Randomized, Multicenter, Double-Blind, Parallel Pilot Study Assessing the Effect of Mechanical Adhesiolysis vs Adhesiolysis with Corticosteroid and Hyaluronidase Administration into the Epidural Space During Epiduroscopy 29584916 2018 03 27 1526-4637 2018 Mar 23 Pain medicine (Malden, Mass.) Pain Med A Randomized, Multicenter, Double-Blind, Parallel Pilot Study Assessing the Effect of Mechanical Adhesiolysis vs Adhesiolysis with Corticosteroid and Hyaluronidase Administration (...) into the Epidural Space During Epiduroscopy. 10.1093/pm/pnx328 Epiduroscopy is a proven method of diagnosis and treatment for chronic radicular pain after spinal surgery, which is known as failed back surgery syndrome (FBSS). The aim of the study was to compare the efficacy of drugs (the enzyme hyaluronidase and corticosteroid DEPO-Medrol) administrated into the epidural space during epiduroscopy, performed within the ventral and ventro-lateral epidural space with a focus on releasing foraminal adhesions. Forty

EvidenceUpdates2018 Full Text: Link to full Text with Trip Pro

40. Corticosteroids for the prevention of bronchopulmonary dysplasia in preterm infants: a network meta-analysis

Corticosteroids for the prevention of bronchopulmonary dysplasia in preterm infants: a network meta-analysis 29475879 2018 02 24 1468-2052 2018 Feb 23 Archives of disease in childhood. Fetal and neonatal edition Arch. Dis. Child. Fetal Neonatal Ed. Corticosteroids for the prevention of bronchopulmonary dysplasia in preterm infants: a network meta-analysis. fetalneonatal-2017-313759 10.1136/archdischild-2017-313759 To determine the comparative efficacy and safety of corticosteroids in the (...) prevention of bronchopulmonary dysplasia (BPD) in preterm infants. We systematically searched PubMed, EMBASE and the Cochrane Library. Two reviewers independently selected randomised controlled trials (RCTs) of postnatal corticosteroids in preterm infants. A Bayesian network meta-analysis and subgroup analyses were performed. We included 47 RCTs with 6747 participants. The use of dexamethasone at either high dose or low dose decreased the risk of BPD (OR 0.29, 95% credible interval (CrI) 0.14 to 0.52

EvidenceUpdates2018