Latest & greatest articles for copd

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Top results for copd

21. COPD exacerbations

COPD exacerbations Top results for copd exacerbations - Trip Database or use your Google+ account Turning Research Into Practice My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search (...) box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for copd exacerbations The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic

Trip Latest and Greatest2018

22. COPD

COPD Top results for copd - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button (...) . An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for copd The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical

Trip Latest and Greatest2018

23. Sleep-disordered Breathing in Patients with COPD

Sleep-disordered Breathing in Patients with COPD AMERICANTHORACICSOCIETY DOCUMENTS ResearchPrioritiesinPathophysiologyforSleep-disorderedBreathing inPatientswithChronicObstructivePulmonaryDisease An Of?cial American Thoracic Society Research Statement Atul Malhotra, Alan R. Schwartz, Hartmut Schneider, Robert L. Owens, Pamela DeYoung, MeiLan K. Han, JadwigaA.Wedzicha,NadiaN.Hansel,MichelleR.Zeidler,KevinC.Wilson,andM.SafwanBadr;onbehalfoftheATS Assembly on Sleep and Respiratory Neurobiology (...) THIS OFFICIAL RESEARCH STATEMENT OF THE AMERICAN THORACIC SOCIETY WAS APPROVED DECEMBER 2017 Background:Obstructivesleepapnea(OSA)andchronic obstructivepulmonarydisease(COPD)arecommonconditions; theco-occurrenceofthesediseases,calledtheoverlapsyndrome (OVS),hasbeenassociatedwithpoorhealthoutcomes. Purpose:ThepurposeofthisOf?cialAmericanThoracicSociety ResearchStatementistodescribepathophysiology,epidemiology, outcomes,diagnosticmetrics,andtreatmentofOVS,aswellasto

American Thoracic Society2018

24. COPD Disease Education in Pulmonary Rehabilitation: A Workshop Report

COPD Disease Education in Pulmonary Rehabilitation: A Workshop Report WORKSHOPREPORT Chronic Obstructive Pulmonary Disease Education in Pulmonary Rehabilitation An Of?cial American Thoracic Society/Thoracic Society of Australia and New Zealand/Canadian Thoracic Society/British Thoracic Society Workshop Report Felicity C. Blackstock, Suzanne C. Lareau, Linda Nici, Richard ZuWallack, Jean Bourbeau, Maria Buckley, StevenJ.Durning,TanjaW.Ef?ng,EllenEgbert,RogerS.Goldstein,William Kelly,AnnemarieLee (...) Society statement on pulmonary rehabilitation (PR), educationtopromoteeffective self-management isacornerstoneof this intervention. Despite education’s stature within PR, there is currently limited evidence supporting its overall ef?cacy, and minimal evidence guiding its optimal design and delivery. This workshop was convened to focus on the current state of education in PR for patients with chronic obstructive pulmonary disease, who are the most common people referred to PR. The workshop

American Thoracic Society2018

25. Microbial and host immune factors as drivers of COPD

Microbial and host immune factors as drivers of COPD 29992131 2018 11 14 2312-0541 4 3 2018 Jul ERJ open research ERJ Open Res Microbial and host immune factors as drivers of COPD. 00015-2018 10.1183/23120541.00015-2018 Compartmentalisation of the respiratory tract microbiota in patients with different chronic obstructive pulmonary disease (COPD) severity degrees needs to be systematically investigated. In addition, it is unknown if the inflammatory and emphysematous milieux in patients (...) with COPD are associated with changes in the respiratory tract microbiota and host macrophage gene expression. We performed a cross-sectional study to compare non-COPD controls (n=10) to COPD patients (n=32) with different disease severity degrees. Samples (n=187) were obtained from different sites of the upper and lower respiratory tract. Microbiota analyses were performed by 16S ribosomal RNA gene sequencing and host gene expression analyses by quantitative real-time PCR of distinct markers

ERJ open research2018 Full Text: Link to full Text with Trip Pro

26. The Impact of Listening to Music During a High-Intensity Exercise Endurance Test in People With COPD

The Impact of Listening to Music During a High-Intensity Exercise Endurance Test in People With COPD 29253555 2018 05 07 1931-3543 153 5 2018 May Chest Chest The Impact of Listening to Music During a High-Intensity Exercise Endurance Test in People With COPD. 1134-1141 S0012-3692(17)33225-7 10.1016/j.chest.2017.12.001 In people with COPD, dyspnea is the primary symptom limiting exercise tolerance. One approach to reducing dyspnea during exercise is through music listening. A constant speed (...) endurance test reflects a high-intensity aerobic exercise training session, but whether listening to music affects endurance time is unknown. This study aimed to determine the effects of listening to music during a constant speed endurance test in COPD. Participants with COPD completed two endurance walk tests, one with and one without listening to self-selected music throughout the test. The primary outcome was the difference in endurance time between the two conditions. Heart rate, percutaneous oxygen

EvidenceUpdates2018

27. COPD

COPD Autosynthesis - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example

Trip Evidence Maps2018

28. Influenza vaccine for chronic obstructive pulmonary disease (COPD).

Influenza vaccine for chronic obstructive pulmonary disease (COPD). BACKGROUND: Influenza vaccinations are currently recommended in the care of people with COPD, but these recommendations are based largely on evidence from observational studies, with very few randomised controlled trials (RCTs) reported. Influenza infection causes excess morbidity and mortality in people with COPD, but there is also the potential for influenza vaccination to cause adverse effects, or not to be cost effective (...) . OBJECTIVES: To determine whether influenza vaccination in people with COPD reduces respiratory illness, reduces mortality, is associated with excess adverse events, and is cost effective. SEARCH METHODS: We searched the Cochrane Airways Trials Register, two clinical trials registries, and reference lists of articles. A number of drug companies we contacted also provided references. The latest search was carried out in December 2017. SELECTION CRITERIA: RCTs that compared live or inactivated virus

Cochrane2018

29. Self management of patients with mild COPD in primary care: randomised controlled trial.

Self management of patients with mild COPD in primary care: randomised controlled trial. OBJECTIVE: To evaluate the effectiveness of telephone health coaching delivered by a nurse to support self management in a primary care population with mild symptoms of chronic obstructive pulmonary disease (COPD). DESIGN: Multicentre randomised controlled trial. SETTING: 71 general practices in four areas of England. PARTICIPANTS: 577 patients with Medical Research Council dyspnoea scale scores of 1 or 2 (...) , recruited from primary care COPD registers with spirometry confirmed diagnosis. Patients were randomised to telephone health coaching (n=289) or usual care (n=288). INTERVENTIONS: Telephone health coaching intervention delivered by nurses, underpinned by Social Cognitive Theory. The coaching promoted accessing smoking cessation services, increasing physical activity, medication management, and action planning (4 sessions over 11 weeks; postal information at weeks 16 and 24). The nurses received two days

BMJ2018 Full Text: Link to full Text with Trip Pro

30. Intrinsic factors influence self-management participation in COPD: effects on self-efficacy

Intrinsic factors influence self-management participation in COPD: effects on self-efficacy 29900178 2018 11 14 2312-0541 4 2 2018 Apr ERJ open research ERJ Open Res Intrinsic factors influence self-management participation in COPD: effects on self-efficacy. 00011-2018 10.1183/23120541.00011-2018 Personal traits should be addressed before offering self-management programmes to patients with COPD http://ow.ly/DtNh30k1A15. de Boer Geertje M GM https://orcid.org/0000-0002-9615-1123 Dept

ERJ open research2018 Full Text: Link to full Text with Trip Pro

31. Beclometasone dipropionate / formoterol fumarate dihydrate / glycopyrronium (Trydonis) - COPD, Chronic Obstructive Pulmonary Disease

Beclometasone dipropionate / formoterol fumarate dihydrate / glycopyrronium (Trydonis) - COPD, Chronic Obstructive Pulmonary Disease 30 Churchill Place ? Canary Wharf ? London E14 5EU ? United Kingdom An agency of the European Union Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5520 Send a question via our website www.ema.europa.eu/contact © European Medicines Agency, 2018. Reproduction is authorised provided the source is acknowledged. 22 February 2018 EMA/155337/2018 Committee (...) 12 Assessment report EMA/155337/2018 Page 3/13 List of abbreviations ADME absorption, distribution, metabolism, and excretion ADR Adverse Drug Reaction AE adverse event AESI adverse event of special interest ALT alanine aminotransferase APSD aerodynamic particle size distribution AST aspartate aminotransferase ATS American Thoracic Society BMI body mass index BUD budesonide CAT COPD Assessment Test CDLM Capacity of Daily Living during the Morning CEC Clinical Endpoint Committee CHMP Committee

European Medicines Agency - EPARs2018

32. Core IM: Mind the Gap on Steriods in COPD

Core IM: Mind the Gap on Steriods in COPD Core IM: Mind the Gap on Steriods in COPD | Clinical Correlations Core IM: Mind the Gap on Steriods in COPD May 30, 2018 Podcast: | Subscribe: | Let’s take your breath away… with a review of the evidence for steroids in treating COPD exacerbations! How long should you treat for? Is IV better than PO? || Written and hosted by Dr. Steve Liu and Dr. Janine Knudsen || Graphic Design by Mr. Ramon Thompson Time Stamps How does GOLD (Global Initiative (...) for Chronic Obstructive Lung Disease) define a COPD exacerbation? (2:44) What outcomes do steroids actually improve in treating a COPD exacerbation? (5:08) What is the evidence behind a 5 day steroid “burst”? (7:20) Are IV steroids more powerful than PO? (9:00) Subscribe to CORE IM on any podcast app! Follow us on Facebook || Twitter || Instagram . Please give any feedback at . Show Notes A moderate to severe COPD exacerbation is defined as at least 2 of the 3 cardinal symptoms : change in baseline

Clinical Correlations2018

33. Tai Chi and Pulmonary Rehabilitation Compared for Treatment-Naive Patients With COPD: A Randomized Controlled Trial

Tai Chi and Pulmonary Rehabilitation Compared for Treatment-Naive Patients With COPD: A Randomized Controlled Trial 29625777 2018 05 07 1931-3543 153 5 2018 May Chest Chest Tai Chi and Pulmonary Rehabilitation Compared for Treatment-Naive Patients With COPD: A Randomized Controlled Trial. 1116-1124 S0012-3692(18)30313-1 10.1016/j.chest.2018.01.053 In COPD, functional status is improved by pulmonary rehabilitation (PR) but requires specific facilities. Tai Chi, which combines psychological (...) (95% CI, 1.9 to 7.0; P < .001), favoring Tai Chi. Similar trends were observed for 6-min walk distance; no change in FEV 1 was observed. Tai Chi is equivalent to PR for improving SGRQ in COPD. Twelve weeks after exercise cessation, a clinically significant difference in SGRQ emerged favoring Tai Chi. Tai Chi is an appropriate substitute for PR. ClinicalTrials.gov; No.: NCT02665130; URL: www.clinicaltrials.gov. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved. Polkey

EvidenceUpdates2018

34. Home treatment of COPD exacerbation selected by DECAF score: a non-inferiority, randomised controlled trial and economic evaluation

Home treatment of COPD exacerbation selected by DECAF score: a non-inferiority, randomised controlled trial and economic evaluation 29680821 2018 04 22 1468-3296 2018 Apr 21 Thorax Thorax Home treatment of COPD exacerbation selected by DECAF score: a non-inferiority, randomised controlled trial and economic evaluation. thoraxjnl-2017-211197 10.1136/thoraxjnl-2017-211197 Previous models of Hospital at Home (HAH) for COPD exacerbation (ECOPD) were limited by the lack of a reliable prognostic (...) Upon Tyne, UK. eng Journal Article 2018 04 21 England Thorax 0417353 0040-6376 copd exacerbations Competing interests: SCB reports grants from NIHR: Research for Patient Benefit Programme, during the conduct of the study; HTA funding, grants from Philips Respironics and Pfizer Open Air, personal fees from Pfizer and AstraZeneca, outside the submitted work. JG reports grants from NIHR Research for Patient Benefit, during the conduct of the study. CE, GJG, TH, AJS and JS have no competing interests

EvidenceUpdates2018

35. Single-inhaler triple therapy in symptomatic COPD patients: FULFIL subgroup analyses

Single-inhaler triple therapy in symptomatic COPD patients: FULFIL subgroup analyses 29750142 2018 11 14 2312-0541 4 2 2018 Apr ERJ open research ERJ Open Res Single-inhaler triple therapy in symptomatic COPD patients: FULFIL subgroup analyses. 00119-2017 10.1183/23120541.00119-2017 Triple inhaled corticosteroid (ICS)/long-acting muscarinic antagonist (LAMA)/long-acting β 2 -agonist (LABA) therapy is recommended for symptomatic patients with chronic obstructive pulmonary disease (COPD) and at (...) risk of exacerbations. However, the benefits versus side-effects of triple inhaled therapy for COPD, based on distinct patient clinical profiles, are unclear. FULFIL, a phase III, randomised, double-blind study, compared 24 weeks of once-daily fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) 100/62.5/25 µg using the Ellipta inhaler with twice-daily budesonide/formoterol (BUD/FOR) 400/12 µg using the Turbuhaler. Subgroup analyses of forced expiratory volume in 1 s (FEV 1 ), St George's

ERJ open research2018 Full Text: Link to full Text with Trip Pro

36. Inspiratory muscle training does not improve clinical outcomes in 3-week COPD rehabilitation: results from a randomised controlled trial

Inspiratory muscle training does not improve clinical outcomes in 3-week COPD rehabilitation: results from a randomised controlled trial 29371382 2018 01 26 1399-3003 51 1 2018 Jan The European respiratory journal Eur. Respir. J. Inspiratory muscle training does not improve clinical outcomes in 3-week COPD rehabilitation: results from a randomised controlled trial. 1702000 10.1183/13993003.02000-2017 The value of inspiratory muscle training (IMT) in pulmonary rehabilitation (...) in chronic obstructive pulmonary disease (COPD) is unclear. The RIMTCORE (Routine Inspiratory Muscle Training within COPD Rehabilitation) randomised controlled trial examined the effectiveness of IMT added to pulmonary rehabilitation.In total, 611 COPD patients (Global Initiative for Chronic Obstructive Lung Disease stage II-IV) received a 3-week inpatient pulmonary rehabilitation, of which 602 patients were included in the intention-to-treat analyses. The intervention group (n=300) received highly intensive IMT and the control group

EvidenceUpdates2018

37. Living with COPD: the struggle for breath and for lung volume reduction therapies

Living with COPD: the struggle for breath and for lung volume reduction therapies 29692995 2018 11 14 2312-0541 4 2 2018 Apr ERJ open research ERJ Open Res Living with COPD: the struggle for breath and for lung volume reduction therapies. 00005-2018 10.1183/23120541.00005-2018 Access to lung volume reduction for advanced emphysema http://ow.ly/Iqru30jbvbE. Mahadeva Ravi R Cambridge COPD Centre, Addenbrookes Hospital, Cambridge, UK. Zoumot Zaid Z Respiratory and Critical Care Institute

ERJ open research2018 Full Text: Link to full Text with Trip Pro

38. Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD.

Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD. Background The benefits of triple therapy for chronic obstructive pulmonary disease (COPD) with an inhaled glucocorticoid, a long-acting muscarinic antagonist (LAMA), and a long-acting β 2 -agonist (LABA), as compared with dual therapy (either inhaled glucocorticoid-LABA or LAMA-LABA), are uncertain. Methods In this randomized trial involving 10,355 patients with COPD, we compared 52 weeks of a once-daily combination (...) of fluticasone furoate (an inhaled glucocorticoid) at a dose of 100 μg, umeclidinium (a LAMA) at a dose of 62.5 μg, and vilanterol (a LABA) at a dose of 25 μg (triple therapy) with fluticasone furoate-vilanterol (at doses of 100 μg and 25 μg, respectively) and umeclidinium-vilanterol (at doses of 62.5 μg and 25 μg, respectively). Each regimen was administered in a single Ellipta inhaler. The primary outcome was the annual rate of moderate or severe COPD exacerbations during treatment. Results The rate

NEJM2018

39. Noninvasive ventilation in stable hypercapnic COPD: what is the evidence?

Noninvasive ventilation in stable hypercapnic COPD: what is the evidence? 29637078 2018 11 14 2312-0541 4 2 2018 Apr ERJ open research ERJ Open Res Noninvasive ventilation in stable hypercapnic COPD: what is the evidence? 00012-2018 10.1183/23120541.00012-2018 Long-term noninvasive ventilation (NIV) to treat chronic hypercapnic respiratory failure is still controversial in severe chronic obstructive pulmonary disease (COPD) patients. However, with the introduction of high-intensity NIV (...) , important benefits from this therapy have also been shown in COPD. In this review, the focus will be on the arguments for long-term NIV at home in patients with COPD. The rise of (high-intensity) NIV in COPD and the randomised controlled trials showing positive effects with this mode of ventilation will be discussed. Finally, the challenges that might be encountered (both in clinical practice and in research) in further optimising this therapy, monitoring and following patients, and selecting

ERJ open research2018 Full Text: Link to full Text with Trip Pro

40. Initial treatment with high-pressure oxygen reduces deaths in severe flare-ups of COPD

Initial treatment with high-pressure oxygen reduces deaths in severe flare-ups of COPD NIHR DC | Signal - Use of a facemask ventilator can reduce deaths in severe flare-ups of COPD Dissemination Centre Discover Portal NIHR DC Discover Use of a facemask ventilator can reduce deaths in severe flare-ups of COPD Published on 19 September 2017 People admitted to hospital with a severe exacerbation of chronic obstructive pulmonary disease (COPD) were 46% less likely to die if they received non (...) -invasive ventilation. Only 12% of those receiving non-invasive ventilation needed subsequent invasive ventilation via a tube, compared to 34% of those who had usual care. This review identified 17 trials of adults with a severe acute exacerbation of COPD with high carbon dioxide levels. Trials compared usual care, including steroids and antibiotics with usual care plus non-invasive ventilation, which delivers air at high pressure via a mask. Airways are forced open and respiratory muscles can rest

NIHR Dissemination Centre2018